Sulfo-Cyanine5.5 carboxylic acid

Sulfo-Cyanine5.5 carboxylic acid,Sulfo-Cyanine5.5(Cy5.5® 的类似物)是一种水溶性、发射远红光的荧光团。 由于四个磺基,该染料在中性pH下具有负电荷,并且具有非常高的亲水性。

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  • Sulfo-Cyanine5.5 carboxylic acid

Sulfo-Cyanine5.5 carboxylic acid

标签:Carboxylic acids, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
17390 1 mg 110.00$ in stock
27390 5 mg 290.00$ 5 days
47390 25 mg 690.00$ in stock
57390 50 mg 1190.00$ in stock
67390 100 mg 1850.00$ in stock

Sulfo-Cyanine5.5 (analog of Cy5.5®) is a water-soluble, far red emitting fluorophore. Due to four sulfo-groups, the dye possesses negative charge in neutral pH, and very high hydrophilicity.

As a cyanine dye, sulfo-Cyanine5.5 shows very low dependence of the fluorescence on pH, and very high extinction coefficient.

Sulfo-Cyanine5.5(Cy5.5® 的类似物)是一种水溶性、发射远红光的荧光团。 由于四个磺基,该染料在中性pH下具有负电荷,并且具有非常高的亲水性。

作为一种花青染料,sulfo-Cyanine5.5 的荧光对 pH 的依赖性非常低,消光系数非常高。

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 carboxylic acid

Sulfo-Cyanine5.5 carboxylic acid相关产品

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cyanine5 azide 是一种用 Cy5(一种流行的荧光染料)进行 Click Chemistry 标记的试剂。

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

水溶性 NIR 染料胺,Cy7 染料的磺化衍生物,用于通过酶促氨基转移进行修饰。

Sulfo-Cyanine7 carboxylic acid

Sulfo-Cy7 carboxylic acid is a non-reactive fluorescent dye which can be used as a NIR (near infrared) marker.

Sulfo-Cy7 羧酸是一种非反应性荧光染料,可用作 NIR(近红外)标记。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 1017.31
CAS number: 2183440-68-6 (inner salt)
Molecular formula: C40H39K3N2O14S4
Solubility: Well soluble in water, DMF, DMSO (0.39 M = 400 g/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献:

  1. So, I.-S.; Kang, J.H.; Hong, J.W.; Sung, S.; Hasan, A.F.; Sa, K.H.; Han, S.W.; Kim, I.S.; Kang, Y.M. A novel apoptosis probe, cyclic ApoPep-1, for in vivo imaging with multimodal applications in chronic inflammatory arthritis. Apoptosis, 2021, 26(3–4), 209–218. doi: 10.1007/s10495-021-01659-z
  2. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  3. Rodríguez-Hakim, M.; Anand, S.; Tajuelo, J.; Yao, Z.; Kannan, A.; Fuller, G.G. Asphaltene-induced spontaneous emulsification: Effects of interfacial co-adsorption and viscoelasticity. Journal of Rheology, 2020, 64(4), 799–816. doi: 10.1122/1.5145307
  4. Wild, A.R.; Sinnen, B.L.; Dittmer, P.J.; Kennedy, M.J.; Sather, W.A.; Dell’Acqua, M.L. Synapse-to-Nucleus Communication through NFAT Is Mediated by L-type Ca2+ Channel Ca2+ Spike Propagation to the Soma. Cell Reports, 2019, 26, 3537–3550.e4. doi: 10.1016/j.celrep.2019.03.005
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide,Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料,由于存在四个磺基,因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

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  • Dye maleimides
  • Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide

标签:Maleimides, Near infrared (NIR) imaging, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
17380 1 mg 110.00$ in stock
27380 5 mg 290.00$ in stock
47380 25 mg 690.00$ in stock
57380 50 mg 1270.00$ in stock
67380 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 dye is a water soluble far red to NIR emitting dye which is very hydrophilic due to the presence of four sulfo groups. Sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is a perfect choice for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers.

This maleimide is a thiol reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.

Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料,由于存在四个磺基,因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

这种马来酰亚胺是一种选择性标记半胱氨酸残基的硫醇活性染料。 根据我们推荐的方案,应使用适当的还原剂(例如 TCEP)还原天然蛋白质的二硫键。

Absorption and emission spectra of sulfo-Cyanine5.5

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide相关产品

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

BDP TMR maleimide

A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.

用于 TAMRA 通道的明亮硫醇活性染料。 可用于显微镜和荧光偏振测定,以及其他应用。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1024.2
Molecular weight: 1139.43
CAS number: 2183440-58-4 (potassium salt); 2183440-57-3 (inner salt)
Molecular formula: C46H45K3N4O15S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 12 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献:

  1. Ieong, K.-W.; Indrisiunaite, G.; Prabhakar, A.; Puglisi, J.D.; Ehrenberg, M. N6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors. Nucleic Acids Research, 2021, 49(5), 2684–2699. doi: 10.1093/nar/gkab033
  2. Chen, Q.; Gao, M.; Li, Z.; Xiao, Y.; Bai, X.; Boakye-Yiadom, K.O.; Xu, X.; Zhang, X.-Q. Biodegradable nanoparticles decorated with different carbohydrates for efficient macrophage-targeted gene therapy. Journal of Controlled Release, 2020, 323, 179–190. doi: 10.1016/j.jconrel.2020.03.044
  3. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0

Sulfo-Cyanine5.5 alkyne

Sulfo-Cyanine5.5 alkyne,Sulfo-Cyanine5.5 是一种远红荧光团。 它含有四个磺基,具有很强的亲水性和水溶性。 该试剂可以通过铜催化的点击化学反应与多种叠氮化物结合。

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  • Sulfo-Cyanine5.5 alkyne

Sulfo-Cyanine5.5 alkyne

标签:Alkynes, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
A73B0 1 mg 110.00$ in stock
B73B0 5 mg 290.00$ in stock
C73B0 10 mg 470.00$ in stock
D73B0 25 mg 690.00$ in stock
E73B0 50 mg 1270.00$ in stock
F73B0 100 mg 1990.00$ in stock
Sulfo-Cyanine5.5 is a far red emitting fluorophore. It contains four sulfo groups, which provide great hydrophilicity, and aqueous solubility. The reagent can be conjugated with a variety of azides by means of copper catalyzed Click chemistry reaction.
Sulfo-Cyanine5.5 是一种远红荧光团。 它含有四个磺基,具有很强的亲水性和水溶性。 该试剂可以通过铜催化的点击化学反应与多种叠氮化物结合。

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 alkyne

Sulfo-Cyanine5.5 alkyne相关产品

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃,5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

Cyanine5.5 alkyne

Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.

Cy5.5 炔烃是一种 NIR(近红外)染料叠氮化物,适用于铜催化和无铜点击化学。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 1054.36
Molecular formula: C43H42N3K3O13S4
IUPAC name: (E)-4-[(2E,4E)-5-{3,3-Dimethyl-5-[6-oxo-6-(2-propynylamino)hexyl]-10-(oxysulfonyl)-12-sulfo-5-azatricyclo[7.4.0.02,6]trideca-1,4,6,8,10,12-hexaen-4-yl}-2,4-pentadienylidene]-3,3-dimethyl-5-methyl-5-azatricyclo[7.4.0.02,6]trideca-1,6,8,10,12-pentaene-10,12-disulfonic acid tripotassium salt
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献:

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1

Sulfo-Cyanine5.5 azide,Cy5.5 叠氮化物

Sulfo-Cyanine5.5 azide,Cy5.5 叠氮化物,Sulfo-Cyanine5.5 是一种水溶性、亲水性荧光团,在光谱的远红色区域具有发射,是 Cy5.5® 的类似物。 与其他花青染料一样,sulfo-Cyanine5.5 具有出色的摩尔消光系数,从而产生明亮的荧光。

  • Products
  • Reactive dyes
  • Dye azides
  • Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide

标签:Azides, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
A7330 1 mg 110.00$ 5 days
B7330 5 mg 290.00$ in stock
C7330 10 mg 470.00$ in stock
D7330 25 mg 690.00$ in stock
E7330 50 mg 1270.00$ in stock
F7330 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 is a water-soluble, hydrophilic fluorophore which possesses emission in far red area of the spectrum, an analog of Cy5.5®. As other cyanine dyes, sulfo-Cyanine5.5 has an outstanding molar extinction coefficient which gives rise to its bright fluorescence.

The molecule contains four sulfo groups that provide hydrophilicity and negative charge to the fluorophore – this minimizes non-specific binding.

The azide group of sulfo-Cyanine5.5 azide can be conjugated with terminal alkynes in the presence of copper(I) catalyst, or with cycloalkynes in copper free strain promoted reaction.

Sulfo-Cyanine5.5 是一种水溶性、亲水性荧光团,在光谱的远红色区域具有发射,是 Cy5.5® 的类似物。 与其他花青染料一样,sulfo-Cyanine5.5 具有出色的摩尔消光系数,从而产生明亮的荧光。

该分子含有四个磺基,可为荧光团提供亲水性和负电荷 – 这最大限度地减少了非特异性结合。

磺基-Cyanine5.5 叠氮化物的叠氮基团可以在铜(I)催化剂存在下与末端炔烃共轭,或在无铜应变促进反应中与环炔烃共轭。

Sulfo-Cyanine5.5 absorption and emission spectra

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide,Cy5.5 叠氮化物相关产品

Cyanine3.5 azide

Cyanine3.5 azide for biomolecule labeling through Click Chemistry.

通过 Click Chemistry 用于生物分子标记的 Cy3.5 叠氮化物。

BDP 581/591 azide

BDP 581/591 is a relatively hydrophobic borondipyrromethene fluorophore that can be used as a probe for ROS species, or fluorescence polarization tracer. This is an azide derivative for Click chemistry.

BDP 581/591 是一种相对疏水的硼二吡咯亚甲基荧光团,可用作 ROS 物种的探针或荧光偏振示踪剂。 这是一种用于点击化学的叠氮化物衍生物。

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cyanine7.5的胺反应性NHS酯。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 984.2
Molecular weight: 1099.41
CAS number: 2382994-65-0
Molecular formula: C43H45K3N6O13S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献:

  1. Erel-Akbaba, G.; Carvalho, L.A.; Tian, T.; Zinter, M.; Akbaba, H.; Obeid, P.J.; Chiocca, E.A.; Weissleder, R.; Kantarci, A.G.; Tannous, B.A. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. ACS Nano, 2019, 13(4), 4028–4040. doi: 10.1021/acsnano.8b08177
  2. Gu, W.; Bobrin, V.A.; Chen, S.-P.R.; Wang, Z.; Schoning, J.P.; Gu, Y.; Chen, W.; Chen, M.; Jia, Z.; Monteiro, M.J. Biodistribution of PNIPAM-Coated Nanostructures Synthesized by the TDMT Method. Biomacromolecules, 2019, 20(2), 625–634. doi: 10.1021/acs.biomac.8b01196
Cy® is a trademark of GE Healthcare.