标签： sulfo-Cyanine5

Sulfo-Cy5 NHS ester

Sulfo-Cy5 NHS ester,sulfo-Cyanine5,NHS esters,Microscopy Protein labeling，Cy 5 琥珀酰亚胺酯 (SE)，相当于 Cy5® NHS 酯，用于在不使用任何有机助溶剂的情况下标记水相中的各种含胺分子。 因此，该产品特别适用于标记在有机共溶剂存在下会变性的蛋白质，以及低溶解度的蛋白质。

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  • Sulfo-Cyanine5 NHS ester

Sulfo-Cyanine5 NHS ester

标签：sulfo-Cyanine5 NHS esters Microscopy Protein labeling
货号 规格 价格 货期
13320 1 mg 110.00$ in stock
23320 5 mg 210.00$ in stock
43320 25 mg 410.00$ in stock
53320 50 mg 695.00$ in stock
63320 100 mg 1190.00$ in stock

Cyanine 5 succinimidyl ester (SE), an equivalent of Cy5® NHS ester, for the labeling of various amine-containing molecules in aqueous phase without use of any organic co-solvent. This product is therefore particularly useful for the labeling of proteins which denature in the presence of organic co-solvents, as well as for proteins with low solubility.

Sulfo-Cyanine 5 is an analog of Cy5®, one of the most popular fluorophores which is compatible with various equipment such as plate readers, microscopes, and imagers.

This dye is highly hydrophilic and water-soluble. A non-sulfonated analog is also available.

Can be used as a replacement for Cy5®, DyLight 649 for all applications.

Cy 5 琥珀酰亚胺酯 (SE)，相当于 Cy5® NHS 酯，用于在不使用任何有机助溶剂的情况下标记水相中的各种含胺分子。 因此，该产品特别适用于标记在有机共溶剂存在下会变性的蛋白质，以及低溶解度的蛋白质。

Sulfo-Cyanine 5 是 Cy5® 的类似物，Cy5® 是最受欢迎的荧光团之一，与读板机、显微镜和成像仪等各种设备兼容。

这种染料是高度亲水和水溶性的。 也可使用非磺化类似物。

可作为 Cy5®、DyLight 649 的替代品用于所有应用。
Sulfo-Cyanine5 NHS ester Sulfo-Cyanine5 NHS ester Sulfo-Cyanine5 NHS ester Sulfo-Cyanine5 NHS ester

Sulfo-Cyanine 5 absorbance and emission spectra

Sulfo-Cyanine5 NHS ester

Sulfo-Cy5 NHS ester相关产品

sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 is a highly hydrophilic near infrared dye for in vivo imaging. This maleimide derivative is useful for the labeling of thiol groups of proteins and peptides.
sulfo-Cyanine7.5 是一种高度亲水的近红外染料，用于体内成像。 这种马来酰亚胺衍生物可用于标记蛋白质和肽的硫醇基团。

sulfo-Cyanine5 DBCO

Water soluble cycloalkyne for copper free Click chemistry reaction with azides. A derivative of sulfo-Cyanine5 aka Cy5.
水溶性环炔烃，用于与叠氮化物的无铜点击化学反应。 磺基-Cyanine5 又名 Cy5 的衍生物。

Cyanine5.5 azide

Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.
用于 Click Chemistry 的远红/近红外荧光 Cyanine5.5 染料衍生物。

General properties

Appearance: dark blue powder
Molecular weight: 777.95
CAS number: 2230212-27-6; 146368-14-1 (N-Ethyl)
Molecular formula: C36H40N3KO10S2
Solubility: very good in water, good in DMF and DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Grohme, M.; Frank, O.; Rink, J. Preparing Planarian Cells for High-content Fluorescence Microscopy Using RNA in situ Hybridization and Immunocytochemistry. preprints.org, preprint. doi: 10.20944/preprints202111.0256.v1
  2. van Hest, J.C.; Song, S.; Mason, A.; Post, R.; de Corato, M.; Mestre, R.; Yewdall, A.; Cao, S.; van der Hofstad, R.; Sanchez, S.; Abdelmohsen, L. Engineering transient dynamics of artificial cells by stochastic distribution of enzymes. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-02c1d
  3. Lee, M.S.; Hyun, H.; Park, I.; Kim, S.; Jang, D.-H.; Kim, S.; Im, J.-K.; Kim, H.; Lee, J.H.; Kwon, T.; Kang, J.H. Quantitative fluorescence in situ hybridization (FISH) of magnetically confined bacteria enables rapid determination of early-stage human bacteremia. medRxiv, preprint. doi: 10.1101/2021.02.19.21251962
  4. Shea, K.; Koide, H.; Okishima, A.; Hoshino, Y.; Kamon, Y.; Yoshimatsu, K.; Saito, K.; Yamauchi, I.; Ariizumi, S.; Oku, N.; Asai, T.; Zhou, Y.; Xiao, T.-H.; Goda, K. Synthetic hydrogel nanoparticles for sepsis therapy. Research Square, preprint. doi: 10.21203/rs.3.rs-150516/v1

Sulfo-Cyanine5 tetrazine

Sulfo-Cyanine5 tetrazine,TCO（四嗪 – 反式环辛烯）连接是用于生物偶联的最快反应之一。 它是在四嗪和反式环辛烯或其他应变烯烃之间发生的逆电子需求[4+2] 环加成。

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  • Sulfo-Cyanine5 tetrazine

Sulfo-Cyanine5 tetrazine

标签：sulfo-Cyanine5,sulfo-Cy5, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
133E0 1 mg 110.00$ in stock
233E0 5 mg 290.00$ in stock
333E0 10 mg 460.00$ in stock
433E0 25 mg 690.00$ in stock
533E0 50 mg 1270.00$ in stock
633E0 100 mg 1990.00$ in stock

TCO (tetrazine – trans-cyclooctene) ligation is one of the fastest reactions used for bioconjugation. It is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefin.

Sulfo-Cyanine5 tetrazine is a fluorophore derivative bearing a tetrazine group for the TCO-ligation based labeling.

This reagent possesses good aqueous solubility and stability in biological environments.

TCO（四嗪 – 反式环辛烯）连接是用于生物偶联的最快反应之一。 它是在四嗪和反式环辛烯或其他应变烯烃之间发生的逆电子需求[4+2] 环加成。

Sulfo-Cyanine5 四嗪是一种带有四嗪基团的荧光团衍生物，用于基于 TCO 连接的标记。

该试剂在生物环境中具有良好的水溶性和稳定性。

Absorption and emission spectra of Sulfo-Cyanine5

Sulfo-Cyanine5 tetrazine

Sulfo-Cyanine5 tetrazine相关产品

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cy3 荧光染料的叠氮化物衍生物。

sulfo-Cyanine3 DBCO

Sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water soluble, general purpose fluorophore sulfo-Cyanine3 for Click Chemistry.

Sulfo-Cyanine3 DBCO 是用于 Click Chemistry 的水溶性通用荧光团 sulfo-Cyanine3 的环炔衍生物。

sulfo-Cyanine5.5 DBCO

Sulfo-Cyanine5.5 DBCO is a far-red, water-soluble reagent for copper-free reaction with azides.

Sulfo-Cyanine5.5 DBCO 是一种远红色的水溶性试剂，用于与叠氮化物的无铜反应。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 864.09
Molecular formula: C42H46KN7O7S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

Sulfo-Cyanine5 amine

Sulfo-Cyanine5 amine,水溶性氨基染料，用于酶促转氨标记，以及与亲电试剂的其他偶联。 Cy5 是一种流行的荧光团，可与不同的荧光测量仪器兼容。

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  • Sulfo-Cyanine5 amine

Sulfo-Cyanine5 amine

标签：sulfo-Cyanine5, Amines,Cy5
货号 规格 价格 货期
133C0 1 mg 110.00$ in stock
233C0 5 mg 290.00$ in stock
433C0 25 mg 690.00$ in stock
533C0 50 mg 1270.00$ in stock
633C0 100 mg 1990.00$ in stock

Water soluble amino dye for enzymatic transamination labeling, and other coupling with electrophiles. Cyanine5 is a popular fluorophore which is compatible with different fluorescence measuring instruments.

Sulfo-Cyanine5 derivatives possess good water solubility.

水溶性氨基染料，用于酶促转氨标记，以及与亲电试剂的其他偶联。 Cyanine5 是一种流行的荧光团，可与不同的荧光测量仪器兼容。

Sulfo-Cyanine5 衍生物具有良好的水溶性。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 amine

Sulfo-Cyanine5 amine相关产品

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

Cyanine3 DBCO

Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper free Click chemistry.

Cy3 dibenzocyclooctyne (DBCO, or ADIBO) 是一种用于无铜点击化学的环炔烃染料衍生物。

TAMRA azide, 5-isomer

TAMRA fluorescent dye azide for Click chemistry.

用于点击化学的 TAMRA 荧光染料叠氮化物。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 740.98
CAS number: 2183440-44-8
Molecular formula: C38H52N4O7S2
IUPAC name: 3H-​Indolium, 1-​[6-​[(6-​aminohexyl)​amino]​-​6-​oxohexyl]​-​2-​[5-​(1,​3-​dihydro-​1,​3,​3-​trimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene)​-​1,​3-​pentadien-​1-​yl]​-​3,​3-​dimethyl-​5-​sulfo-​, inner salt
Solubility: moderate in water, well soluble in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Schotman, M.J.G.; Peters, M.M.C.; Krijger, G.C.; van Adrichem, I.; de Roos, R.; Bemelmans, J.L.M.; Pouderoijen, M.J.; Rutten, M.G.T.A.; Neef, K.; Chamuleau, S.A.J.; Dankers, P.Y.W. In Vivo Retention Quantification of Supramolecular Hydrogels Engineered for Cardiac Delivery. Advanced Healthcare Materials, 2021, 10(10), e2001987. doi: 10.1002/adhm.202001987
  2. Bos, I.; Timmerman, M.; Sprakel, J. FRET-Based Determination of the Exchange Dynamics of Complex Coacervate Core Micelles. Macromolecules, 2021, 54(1), 398–411. doi: 10.1021/acs.macromol.0c02387
  3. Mahmoud, A.M.; Morrow, J.P.; Pizzi, D.; Azizah, A.M.; Davis, T.P.; Tabor, R.F.; Kempe, K. Tuning Cellular Interactions of Carboxylic Acid Side Chain Containing Polyacrylates: The Role of Cyanine Dye Label and Side Chain Type. Biomacromolecules, 2020, 21(8), 3007–3016. doi: 10.1021/acs.biomac.0c00244
  4. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, 2019, 2(11), 5164–5173. doi: 10.1021/acsabm.9b00811
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 carboxylic acid

Sulfo-Cyanine5 carboxylic acid,非活化磺基花青5羧酸，水溶性染料。 这种染料是高度亲水和水溶性的。 非磺化类似物可用。

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  • Sulfo-Cyanine5 carboxylic acid

Sulfo-Cyanine5 carboxylic acid

标签：sulfo-Cyanine5,sulfo-Cy5,Carboxylic acids
货号 规格 价格 货期
13390 1 mg 110.00$ in stock
23390 5 mg 210.00$ in stock
43390 25 mg 410.00$ in stock
53390 50 mg 695.00$ in stock
63390 100 mg 1190.00$ in stock

Non-activated sulfo-Cyanine5 carboxylic acid, water soluble dye. This dye is highly hydrophilic and water-soluble. Non-sulfonated analog is available.

The fluorophore is an equivalent of Cy5® carboxylic acid.

For labeling applications consider using pre-activated sulfo-Cy5 NHS ester

非活化磺基花青5羧酸，水溶性染料。 这种染料是高度亲水和水溶性的。 非磺化类似物可用。

荧光团相当于 Cy5® 羧酸。

对于标签应用，考虑使用预活化的磺基-Cy5 NHS 酯

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 carboxylic acid

Sulfo-Cyanine5 carboxylic acid相关产品

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

Cyanine7.5 carboxylic acid

Cyanine7.5 – unactivated NIR cyanine dye carboxylic acid.

Cy7.5 – 未活化的近红外花青染料羧酸。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 680,87
CAS number: 1144107-82-3 (potassium salt), 1121756-16-8 (inner salt), 2098639-31-5 (sodium salt)
Molecular formula: C32H37N2KO8S2
Solubility: Well soluble in water, DMF, DMSO (0.35 M = 240 g/L). Practically insoluble in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Sun, X.; Du, J.D.; Hawley, A.; Tan, A.; Boyd, B.J. Magnetically-stimulated transformations in the nanostructure of PEGylated phytantriol-based nanoparticles for on-demand drug release. Colloids and Surfaces B: Biointerfaces, 2021, 207, 112005. doi: 10.1016/j.colsurfb.2021.112005
  2. Novoselova, M.V.; Abakumova, T.O.; Khlebtsov, B.N.; Zatsepin, T.S.; Lazareva, E.N.; Tuchin, V.V.; Zharov, V.P.; Gorin, D.A.; Galanzha, E.I. Optical clearing for photoacoustic lympho- and angiography beyond conventional depth limit in vivo. Photoacoustics, 2020, 20, 100186. doi: 10.1016/j.pacs.2020.100186
  3. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  4. Pfister, J.; Summer, D.; Petrik, M.; Khoylou, M.; Lichius, A.; Kaeopookum, P.; Kochinke, L.; Orasch, T.; Haas, H.; Decristoforo, C. Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores. Biomolecules, 2020, 10, 168. doi: 10.3390/biom10020168
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide,水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

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  • Dye maleimides
  • Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide

标签：sulfo-Cyanine5, Cy5,Maleimides, Microscopy
货号 规格 价格 货期
13380 1 mg 110.00$ in stock
23380 5 mg 290.00$ in stock
43380 25 mg 690.00$ in stock
53380 50 mg 1270.00$ in stock
63380 100 mg 1990.00$ in stock

A water soluble, hydrophilic sulfo-Cyanine5 maleimide (Cy5® maleimide analog). We recommend this product for protein labeling, including labeling of antibodies as a perfect replacement for Cy5® maleimide. Labeled proteins can be easily separated from unreacted dye by gel filtration, spin column purification, dialysis, electrophoresis or chromatography.

An analog without sulfo groups, Cyanine5 maleimide, is also available.

水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

也可使用不含磺基的类似物 Cyanine5 马来酰亚胺。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide相关产品

TAMRA azide, 6-isomer

Pure 6-isomer of tetramethylrhodamine (TAMRA) dye, azide derivative for copper-catalyzed and copper-free Click chemistry reactions with alkynes.

纯 6 异构体的四甲基罗丹明 (TAMRA) 染料，叠氮化物衍生物，用于与炔烃的铜催化和无铜点击化学反应。

ROX NHS ester, 6- isomer

Pure isomer 6-ROX NHS ester for amine labeling.

用于胺标记的纯异构体 6-ROX NHS 酯。

Sulfo-Cyanine5 amine

Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.

磺化的 Cy5 胺衍生物，用于与亲电试剂偶联和酶促转氨标记。

General properties

Appearance: dark blue powder  深蓝色粉末
Molecular weight: 803.00
CAS number: 2242791-82-6
Molecular formula: C38H43KN4O9S2
Solubility: soluble in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-7rngq
  2. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, in press. doi: 10.1016/j.ab.2020.113895
  3. Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448–5464.e22. doi: 10.1016/j.cell.2021.09.016
  4. Hurley, C.M.; Kraut, D.A. Determination of Proteasomal Unfolding Ability. Methods in Molecular Biology, 2021, 2365, 217–244. doi: 10.1007/978-1-0716-1665-9_12
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne,用于 Click Chemistry 的具有炔基的水溶性试剂。 Sulfo-Cyanine5 是一种磺化染料，具有高亲水性和水溶性、极高的消光系数、良好的量子产率和与多种仪器的兼容性。

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  • Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne

标签：sulfo-Cyanine5, Cy5, Alkynes, Microscopy
货号 规格 价格 货期
A33B0 1 mg 110.00$ in stock
B33B0 5 mg 290.00$ in stock
C33B0 10 mg 470.00$ in stock
D33B0 25 mg 690.00$ in stock
E33B0 50 mg 1270.00$ in stock
F33B0 100 mg 1990.00$ in stock

This reagent is recommended for the conjugation with proteins, nanoparticles, and other applications where hydrophilicity is important.

用于 Click Chemistry 的具有炔基的水溶性试剂。 Sulfo-Cyanine5 是一种磺化染料，具有高亲水性和水溶性、极高的消光系数、良好的量子产率和与多种仪器的兼容性。

该试剂推荐用于与蛋白质、纳米颗粒和亲水性很重要的其他应用结合。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne

Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.

用于与活化酯和环氧化物偶联的Cy5 胺官能化染料。

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 is a near infrared fluorophore similar to indocyanine green (ICG), but possessing higher fluorescence quantum yield. The dye is very hydrophilic and water soluble. The reagent is very useful for the labeling of biomolecules for in vivo imaging. This is an alkyne for copper catalyzed Click chemistry.

Sulfo-Cy7.5 是一种类似于吲哚菁绿 (ICG) 的近红外荧光团，但具有更高的荧光量子产率。 该染料是非常亲水和水溶性的。 该试剂对于标记用于体内成像的生物分子非常有用。 这是一种用于铜催化点击化学的炔烃。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 717.94
CAS number: 1617572-09-4 (inner salt); 1617497-19-4 (sodium salt)
Molecular formula: C35H40N3KO7S2
Solubility: very high in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a “multiple gear” regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  3. Maklakova, S.Y.; Naumenko, V.A.; Chuprov, A.D.; Mazhuga, M.P.; Zyk, N.V.; Beloglazkina, E.K.; Majouga, A.G. Cellular uptake of N-acetyl-d-galactosamine-, N-acetyl-d-glucosamine- and d-mannose-containing fluorescent glycoconjugates investigated by liver intravital microscopy. Carbohydrate Research, 2020, 489, 107928. doi: 10.1016/j.carres.2020.107928
  4. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, 2019, 2(11), 5164–5173. doi: 10.1021/acsabm.9b00811
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5 azide,Cy5 叠氮化物

Sulfo-Cyanine5 azide,Cy5 叠氮化物,用于点击化学的水溶性 Cyanine5 染料叠氮化物。 具有红色荧光的明亮且光稳定的染料。 该试剂具有高水溶性。 由于高溶解度和亲水性，该染料可用于在天然、纯水性条件下标记生物分子。

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  • Sulfo-Cyanine5 azide

Sulfo-Cyanine5 azide

标签：sulfo-Cyanine5,Cy5, Azides, Microscopy
货号 规格 价格 货期
A3330 1 mg 110.00$ in stock
B3330 5 mg 290.00$ in stock
C3330 10 mg 470.00$ in stock
D3330 25 mg 690.00$ in stock
E3330 50 mg 1270.00$ in stock
F3330 100 mg 1990.00$ in stock

Water-soluble Cyanine5 dye azide for Click chemistry. Bright and photostable dye with red fluorescence. The reagent has high water solubility. Due to high solubility and hydrophilicity, the dye can be used for labeling biomolecules in native, purely aqueous conditions.

This reagent, as opposed to competing products, is supplied as an alkaline metal salt and not triethylammonium salt. Therefore, it is a powder which is easy to handle and dispense.

Sulfo-Cyanine5 is an analog of Cy5®, a very popular fluorophore, therefore this reagent is compatible to a wide range of standard fluorescent instrumentation such as imagers, plate readers, and microscopes.

用于点击化学的水溶性 Cyanine5 染料叠氮化物。 具有红色荧光的明亮且光稳定的染料。 该试剂具有高水溶性。 由于高溶解度和亲水性，该染料可用于在天然、纯水性条件下标记生物分子。

与竞争产品不同，该试剂以碱金属盐而非三乙基铵盐的形式提供。 因此，它是一种易于处理和分配的粉末。

Sulfo-Cyanine5 是 Cy5® 的类似物，Cy5® 是一种非常流行的荧光团，因此该试剂与各种标准荧光仪器兼容，例如成像仪、读板机和显微镜。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 azide

Sulfo-Cyanine5 azide,Cy5 叠氮化物相关产品

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

Sulfo-Cyanine7 maleimide

Water soluble near infrared dye maleimide for the labeling of proteins and peptides.

水溶性近红外染料马来酰亚胺，用于标记蛋白质和肽。

Alkyne Phosphoramidite, 5′-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.

用于合成寡核苷酸的炔亚磷酰胺，可用于点击化学。

General properties

Appearance: dark blue crystals 深蓝色晶体
Molecular weight: 762.98
Molecular formula: C35H43N6KO7S2
Solubility: very high in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Rueda-Alaña, E.; García-Moreno, F. Time in Neurogenesis: Conservation of the Developmental Formation of the Cerebellar Circuitry. Brain, Behavior and Evolution. doi: 10.1159/000519068
  2. Singh, A.; Jothiprakasam, T.; Raghavan, J.V.; Jhunjhunwala, S. Sterile Inflammation Alters Neutrophil Kinetics in Mice. bioRxiv, preprint. doi: 10.1101/2021.02.12.430891
  3. Toyonaga, T.; Keith, B.P.; Barrow, J.B.; Schaner, M.S.; Wolber, E.A.; Beasley, C.; Huling, J.; Wang, Y.; Allbritton, N.L.; Chaumont, N.; Sadiq, T.S.; Koruda, M.j.; Rahbar, R.; Furey, T.S.; Sethupathy, P.; Sheikh, S.Z. Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier integrity and is associated with a poor clinical outcome in Crohn’s disease. bioRxiv, preprint. doi: 10.1101/2020.02.21.960070
  4. Hinman, S.; Wang, Y.; Allbritton, N. Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models. ChemRxiv, preprint. doi: 10.26434/chemrxiv.9759605.v1
Cy® is a trademark of GE Healthcare.