Sulfo-Cy5.5 NHS ester

Sulfo-Cy5.5 NHS ester,Sulfo-Cy5.5 NHS 酯是磺化远红 Cy5.5 荧光团(Cy5.5® 的类似物)的胺反应活性酯。 这是标记抗体、敏感蛋白质和其他需要在纯水环境中反应或无需大量添加有机助溶剂的试剂的首选试剂。

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  • Sulfo-Cyanine5.5 NHS ester

Sulfo-Cy5.5 NHS ester

标签:NHS esters Near infrared (NIR) imaging Microscopy Protein labeling sulfo-Cy5.5
货号 规格 价格 货期
17320 1 mg 110.00$ in stock
27320 5 mg 290.00$ in stock
47320 25 mg 690.00$ in stock
57320 50 mg 1190.00$ 5 days
67320 100 mg 1850.00$ in stock

Sulfo-Cyanine5.5 NHS ester is an amine reactive activated ester of sulfonated far red Cyanine5.5 fluorophore, an analog of Cy5.5®. This is a reagent of choice for the labeling of antibodies, sensitive proteins, and others which require reactions in purely aqueous environment, or without any significant additions of organic co-solvents.

The dye is well suitable for non-invasive in vivo NIR imaging, and for the applications requiring low fluorescent background.

Sulfo-Cy5.5 NHS 酯是磺化远红 Cy5.5 荧光团(Cy5.5® 的类似物)的胺反应活性酯。 这是标记抗体、敏感蛋白质和其他需要在纯水环境中反应或无需大量添加有机助溶剂的试剂的首选试剂。

该染料非常适用于非侵入性体内近红外成像,以及需要低荧光背景的应用。
Sulfo-Cyanine5.5 NHS ester Sulfo-Cyanine5.5 NHS ester Sulfo-Cyanine5.5 NHS ester Sulfo-Cyanine5.5 NHS ester

Absorption and emission spectra of sulfo-Cyanine5.5 fluorophore

Sulfo-Cyanine5.5 NHS ester

Sulfo-Cy5.5 NHS ester相关产品

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for Click chemistry.
Sulfo-Cyanine5 是一种用于 Click 化学的水溶性 Cyanine5 染料炔烃。

Cyanine7 azide

Near-infrared fluorescent dye for Click Chemistry.
用于点击化学的近红外荧光染料。

General properties

Appearance: dark blue solid
Mass spec M+ increment: 884.15
Molecular weight: 1114.37
CAS number: 2419286-92-1
Molecular formula: C44H42N3K3O16S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 675
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 694
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献:

  1. Liu, Q.; Tian, J.; Liu, J.; Zhu, M.; Gao, Z.; Hu, X.; Midgley, A.C.; Wu, J.; Wang, Xi.; Kong, D.; Zhuang, J.; Liu, J.; Yan, X.; Huang, X. Modular Assembly of Tumor-Penetrating and Oligomeric Nanozyme Based on Intrinsically Self-Assembling Protein Nanocages. Advanced Materials, 2021, 33(39), 2103128. doi: 10.1002/adma.202103128
  2. Lu, Z.; Zhang, Y.; Wang, Y.; Tan, G.-H.; Huang, F.-Y.; Cao, R.; He, N.; Zhang, L. A biotin-avidin-system-based virus-mimicking nanovaccine for tumor immunotherapy. Journal of Controlled Release, 2021, 332, 245–259. doi: 10.1016/j.jconrel.2021.02.029
  3. Shramova, E.; Proshkina, G.; Shipunova, V.; Ryabova, A.; Kamyshinsky, R.; Konevega, A.; Schulga, A.; Konovalova, E.; Telegin, G.; Deyev, S. Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape. Cancers, 2020, 12(10), 3014. doi: 10.3390/cancers12103014
  4. Peplau, E.; De Rose, F.; Reder, S.; Mittelhaeuser, M.; Scafetta, G.; Schwaiger, M.; Weber, W.A.; Bartolazzi, A.; Skerra, A.; D’Alessandria, C. Development of a chimeric Fab directed against human galectin-3 and validation as an immune-PET tracer for the sensitive in vivo imaging of thyroid cancer. Thyroid, 2020, 30(9), 1314–1326. doi: 10.1089/thy.2019.0670
Cy® is a trademark of GE Healthcare.

Sulfo-Cy5.5 dUTP

Sulfo-Cy5.5 dUTP,Sulfo-Cy5.5 是一种发射远红光的染料。 由于几乎没有荧光背景的生物源在其范围内发射,因此这种荧光团提供了很好的信噪比。,储存:收到后 12 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下和过度冻融循环。

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  • Sulfo-Cyanine5.5 dUTP

Sulfo-Cyanine5.5 dUTP

标签:PCR and qPCR, Triphosphates, sulfo-Cyanine5.5
货号 规格 价格 货期
2071-50nmol 50 nmol 290.00$ in stock
2071-250nmol 250 nmol 950.00$ 5 days

Sulfo-Cyanine5.5 is a far red emitting dye. Since almost no biological sources of fluorescence background emit in its range, this fluorophore provides great signal to noise ratio.

This molecule is a modified deoxyuridine triphosphate (dUTP) that is a substrate to many enzymes including simple Taq polymerase. Due to its extended amino-11-linker, this reagent provides a better alternative to aminoallyl derived triphosphates with dyes.

The QC of triphosphates includes HPLC-MS and enzymatic testing.

Sulfo-Cy5.5 是一种发射远红光的染料。 由于几乎没有荧光背景的生物源在其范围内发射,因此这种荧光团提供了很好的信噪比。

该分子是一种修饰的脱氧尿苷三磷酸 (dUTP),它是许多酶的底物,包括简单的 Taq 聚合酶。 由于其扩展的氨基 11 接头,该试剂为氨基烯丙基衍生的三磷酸盐和染料提供了更好的替代品。

三磷酸盐的 QC 包括 HPLC-MS 和酶促测试。

Absorption and emission spectra of sulfo-Cyanine5.5

Sulfo-Cyanine5.5 dUTP

Sulfo-Cy5.5 dUTP相关产品

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cy5 活化酯,用于标记蛋白质、肽和其他分子。

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cy5 azide 是一种用 Cy5(一种流行的荧光染料)进行 Click Chemistry 标记的试剂。

dsGreen for Real-Time PCR, 100×

Stock solution of dsGreen for Real-Time PCR, 100×

用于实时 PCR 的 dsGreen 储备溶液,100×

General properties

Appearance: blue solid / solution 蓝色固体/溶液
Molecular weight: 1554.97
Molecular formula: C58H63N6Li6O28P3S4
Quality control: HPLC-MS (95%), testing in enzymatic reaction
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light and excessive freeze-thaw cycles.储存:收到后 12 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下和过度冻融循环。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 DBCO,Sulfo-Cy5.5 是一种具有接近 NIR 范围的远红发射的染料。 它已在非侵入性活体成像中得到应用。 这种特殊的磺基-Cy5.5 衍生物,即 DBCO(或 ADIBO)衍生物,含有环炔烃,用于无铜共轭这种荧光团与各种有机叠氮化物。

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  • sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 DBCO

标签:Copper free Click chemistry, Cycloalkyne, sulfo-Cy5.5
货号 规格 价格 货期
173F0 1 mg 110.00$ in stock
273F0 5 mg 290.00$ in stock
473F0 25 mg 690.00$ in stock
573F0 50 mg 1270.00$ in stock
673F0 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 is a dye with far-red emission approaching NIR range. It has found application in non-invasive live-organism imaging. This particular derivative of sulfo-Cyanine5.5, the DBCO (or ADIBO) derivative, contains cycloalkyne for copper-free conjugation of this fluorophore with various organic azides.

The reaction between DBCO and azides is blazingly fast, orders of magnitude exceeding the rate of copper-catalyzed reaction between azides and terminal alkynes. It is also catalyst-free.

This reagent can be used to conjugate sulfo-Cyanine5.5 dye to a variety of azide-labeled molecules.

Sulfo-Cy5.5 是一种具有接近 NIR 范围的远红发射的染料。 它已在非侵入性活体成像中得到应用。 这种特殊的磺基-Cyanine5.5 衍生物,即 DBCO(或 ADIBO)衍生物,含有环炔烃,用于无铜共轭这种荧光团与各种有机叠氮化物。

DBCO 和叠氮化物之间的反应非常快,数量级超过了铜催化的叠氮化物和末端炔烃之间的反应速率。 它也不含催化剂。

该试剂可用于将磺基-Cyanine5.5 染料与多种叠氮化物标记的分子结合。

Absorption and emission spectra of sulfo-Cyanine5.5

sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 DBCO相关产品

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物,用于与反式环辛烯和其他应变烯烃的 TCO 连接。

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

Biotin-PEG3-Azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Biotin azide 是一种用生物素(一种众所周知的亲和探针)进行点击化学标记的试剂。

General properties

Appearance: dark blue solid
Molecular weight: 1317.69
Molecular formula: C61H59N4K3O14S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11