标签： ProSpec-TNFSF8 Human

Tumor necrosis factor ligand superfamily member 8, CD30 ligand, CD30-L, CD153, TNFSF8, CD30L, CD30LG, CD30 Antigen Ligand, CD153 Antigen.

肿瘤坏死因子配体超家族成员 8、CD30 配体、CD30-L、CD153、TNFSF8、CD30L、CD30LG、CD30 抗原配体、CD153 抗原。

CD30 Ligand is a cytokine which is a member of the tumor necrosis factor ligand family. The TNFSF8 cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The employment of the TNFSF8 cytokine expressed on B cell surface has an inhibitory role in modulating Ig class switch. TNFSF8 enhances cell proliferation of some lymphoma cell lines, while inducing cell death and reducing cell proliferation of other lymphoma cell lines. The pleiotropic biological activities of the TNFSF8 cytokine on different CD30+ lymphoma cell lines has a pathophysiologic role in Hodgkin’s and some non-Hodgkin’s lymphomas.

CD30 配体是一种细胞因子，是肿瘤坏死因子配体家族的成员。 TNFSF8 细胞因子是 TNFRSF8/CD30 的配体，TNFRSF8/CD30 是细胞表面抗原，也是霍奇金淋巴瘤和相关血液恶性肿瘤的标志物。 B 细胞表面表达的 TNFSF8 细胞因子的使用在调节 Ig 类转换中具有抑制作用。 TNFSF8增强一些淋巴瘤细胞系的细胞增殖，同时诱导细胞死亡并减少其他淋巴瘤细胞系的细胞增殖。 TNFSF8 细胞因子对不同 CD30+ 淋巴瘤细胞系的多效生物学活性在霍奇金和一些非霍奇金淋巴瘤中具有病理生理作用。

Escherichia Coli.

Sterile Filtered clear solution.

TNFSF8 protein solution contains 20mM Tris-HCl buffer , 10% glycerol and 0.4M Urea.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Please avoid freeze thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
请避免冻融循环。

Greater than 80% as determined by -PAGE.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。