标签： ProSpec-TNFSF14 Human

Tumor necrosis factor ligand superfamily member 14, CD258, Tnfsf14, Light

TNFRSF14, a member of the TNF receptor superfamily, is a type I transmembrane protein. TNFRSF14 is expressed in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. TNFRSF14 operates as a co-stimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. Additionally, TNFRSF14 encourages the proliferation of T cells, and triggers apoptosis of various tumor cells.

TNFRSF14 是 TNF 受体超家族的成员，是一种 I 型跨膜蛋白。 TNFRSF14 在外周血 T 细胞、B 细胞、单核细胞和富含淋巴细胞的各种组织中表达。 TNFRSF14 作为激活淋巴样细胞的共刺激因子和对疱疹病毒感染的威慑物起作用。 此外，TNFRSF14 促进 T 细胞的增殖，并引发各种肿瘤细胞的凋亡。

Recombinant Human LIGHT having a Mw of 43kDa was purified from E. coli.
The Recombinant Human LIGHT is fused to GST tag at its N terminal and purified by proprietary chromatographic technique.

从大肠杆菌中纯化具有 43kDa 分子量的重组人 LIGHT。
Recombinant Human LIGHT 在其 N 末端与 GST 标签融合，并通过专有色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered clear solution.

TNFSF14 solution contains 25mM Tris-Base/ 25mM K₂CO_3.

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

DGPAGSWEQL IQERRSHEVN PAAHLTGANS SLTGSGGPLL WETQLGLAFL RGLSYHDGAL VVTKAGYYYI YSKVQLGGVG CPLGLASTIT HGLYKRTPRY PEELELLVSQ QSPCGRATSS SRVWWDSSFL GGVVHLEAGE KVVVRVLDER LVRLRDGTRS YFGAFMV

Protein is >95% pure as determined by 10% PAGE .

Immunoassay.

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