ProSpec-TNFRSF6B Human/CYT-799

ProSpec-TNFRSF6B Human,ProSpec CYT-799,TNFRSF6B 是肿瘤坏死因子受体超家族的成员。 TNFRSF6B 作为诱饵受体与死亡受体竞争配体结合。 除了通过中和 TL1A 诱导血管生成外,TNFRSF6B 在抑制 FasL 和 LIGHT 介导的细胞死亡和 T 细胞活化方面具有调节作用。

TNFRSF6B Human

Tumor Necrosis Factor Receptor Superfamily, Member 6b Human Recombinant
CYT-799
ProSpec-TNFRSF6B Human/CYT-799 5µg
ProSpec-TNFRSF6B Human/CYT-799 20µg
ProSpec-TNFRSF6B Human/CYT-799 1mg

Catalogue number

CYT-799

Synonyms

Tumor Necrosis Factor Receptor Superfamily, Member 6b Decoy, Decoy Receptor For Fas Ligand, Decoy Receptor 3, DCR3, M68E, M68, TR6, DJ583P15.1.1, DcR3.

Introduction

TNFRSF6B is a member of the Tumor necrosis factor receptor superfamily. TNFRSF6B performs as a decoy receptor which races against death receptors for ligand binding. TNFRSF6B has a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation in addition to inducing angiogenesis via neutralization of TL1A.
TNFRSF6B 是肿瘤坏死因子受体超家族的成员。 TNFRSF6B 作为诱饵受体与死亡受体竞争配体结合。 除了通过中和 TL1A 诱导血管生成外,TNFRSF6B 在抑制 FasL 和 LIGHT 介导的细胞死亡和 T 细胞活化方面具有调节作用。

Description

TNFRSF6B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 294 amino acids and having a molecular mass of 32.1kDa.
TNFRSF6B is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 TNFRSF6B Human Recombinant 是一条单一的、非糖基化的多肽链,包含 294 个氨基酸,分子量为 32.1kDa。
TNFRSF6B 在 N 末端与 23 个氨基酸的 His-tag 融合,并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

TNFRSF6B protein solution containing 20mM Tris-HCl buffer , 0.4M Urea and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Please avoid freeze thaw cycles.
如果整个小瓶将在 2-4 周内使用,请在 4°C 下储存。 储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
请避免冻融循环。

Purity

Greater than 85% as determined by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSVAETPTY PWRDAETGER LVCAQCPPGT FVQRPCRRDS PTTCGPCPPR HYTQFWNYLE RCRYCNVLCG EREEEARACH ATHNRACRCR TGFFAHAGFC LEHASCPPGA GVIAPGTPSQ NTQCQPCPPG TFSASSSSSE QCQPHRNCTA LGLALNVPGS SSHDTLCTSC TGFPLSTRVP GAEECERAVI DFVAFQDISI KRLQRLLQAL EAPEGWGPTP RAGRAALQLK LRRRLTELLG AQDGALLVRL LQALRVARMP GLERSVRERF LPVH.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。