Neurotrophic Receptor Tyrosine Kinase 2 Human Recombinant
CYT-1159
ProSpec-NTRK2 Human/CYT-1159 2µg
ProSpec-NTRK2 Human/CYT-1159 10µg
ProSpec-NTRK2 Human/CYT-1159 1mg
Catalogue number
CYT-1159
Synonyms
GP145-TrkB, trk-B, TRKB, NTRK2
Introduction
Neurotrophic Receptor Tyrosine Kinase 2, also referred to NTRK2, is a tyrosine-protein kinase receptor which takes part in the development & the maturation of the central and the peripheral nervous systems through regulation of neuron survival, migration, proliferation, differentiation and synapse formation & plasticity. NTRK2 acts in learning and memory by regulating both short term synaptic function and long-term potentiation. The substrates that are known for the TRK family receptors are: SHC1, PI-3 kinase and PLC-gamma-1.
神经营养受体酪氨酸激酶 2,也称为 NTRK2,是一种酪氨酸蛋白激酶受体,通过调节神经元存活、迁移、增殖、分化和突触形成,参与中枢和外周神经系统的发育和成熟。 可塑性。 NTRK2 通过调节短期突触功能和长期增强作用在学习和记忆中。 TRK 家族受体的已知底物是:SHC1、PI-3 激酶和 PLC-γ-1。
Description
NTRK2 Human produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 407 amino acids and having a molecular mass of 45.2kDa.
NTRK2 is fused to an 8 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒细胞中产生的 NTRK2 Human 是一条糖基化多肽链,包含 407 个氨基酸,分子量为 45.2kDa。
NTRK2 在 C 末端与 8 个氨基酸的 His 标签融合,并通过专有色谱技术进行纯化。
Source
Sf9, Baculovirus cells.
Physical Appearance
Formulation
The NTRK2 solution contains 10% Glycerol and Phosphate-Buffered Saline .
Stability
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 95% as determined by -PAGE.
Amino acid sequence
CPTSCKCSAS RIWCSDPSPG IVAFPRLEPN SVDPENITEI FIANQKRLEI INEDDVEAYV GLRNLTIVDS GLKFVAHKAF LKNSNLQHIN FTRNKLTSLS RKHFRHLDLS ELILVGNPFT CSCDIMWIKT LQEAKSSPDT QDLYCLNESS KNIPLANLQI PNCGLPSANL AAPNLTVEEG KSITLSCSVA GDPVPNMYWD VGNLVSKHMN ETSHTQGSLR ITNISSDDSG KQISCVAENL VGEDQDSVNL TVHFAPTITF LESPTSDHHW CIPFTVKGNP KPALQWFYNG AILNESKYIC TKIHVTNHTE YHGCLQLDNP THMNNGDYTL IAKNEYGKDE KQISAHFMGW PGIDDGANPN YPDVIYEDYG TAANDIGDTT NRSNEIPSTD VTDKTGREHL EHHHHHH
Usage
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