NPPA Human
Natriuretic Peptide A Human Recombinant
CYT-1028
ProSpec-NPPA Human/CYT-1028 2µg
ProSpec-NPPA Human/CYT-1028 10µg
ProSpec-NPPA Human/CYT-1028 1mg
Catalogue number
CYT-1028
Synonyms
Natriuretic peptides A, CDD-ANF, Cardiodilatin, CDD, Cardiodilatin-related peptide, CDP, N-terminal proatrial natriuretic peptide, ANP, PND.
Introduction
Natriuretic Peptide A is a part of the natriuretic peptide family and is involved in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. NPPA is synthesized as a great precursor which releases a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. In female pregnancy, NPPA is promoting trophoblast invasion and spiral artery remodeling in uterus.
利钠肽 A 是利钠肽家族的一部分,通过调节利钠、利尿和血管舒张参与心血管稳态。 NPPA 被合成为一种伟大的前体,它从 N 端释放一种与血管活性肽、心脏扩张肽相似的肽,并从 C 端释放另一种具有利钠利尿活性的肽。 在女性妊娠期,NPPA 促进子宫内滋养层侵袭和螺旋动脉重塑。
Description
NPPA Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 106 amino acids including an 8 a.a N-terminal His tag. The total molecular mass is 11.7kDa .
在大肠杆菌中产生的 NPPA Human Recombinant 是一种单一的、非糖基化的多肽链,包含 106 个氨基酸,包括一个 8 个氨基酸的 N 端 His 标签。 总分子量为11.7kDa。
Source
Physical Appearance
Formulation
NPPA filtered and lyophilized from 0.5mg/ml in 20 mM Tris buffer, 50 mM NaCl and 5% w/v trehalosa, pH 7.5.
Solubility
It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. NPPA is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
建议加入去离子水配制约 0.5mg/ml 的工作原液,让冻干颗粒完全溶解。 NPPA 不是无菌的! 在细胞培养中使用之前,请用适当的无菌过滤器过滤产品。
Stability
Purity
Greater than 95.0% as determined by -PAGE.
Amino acid sequence
MKHHHHHHNP MYNAVSNADL MDFKNLLDHL EEKMPLEDEV VPPQVLSEPN EEAGAALSPL PEVPPWTGEV SPAQRDGGAL GRGPWDSSDR SALLKSKLRA LLTAPR.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 它们不得用作药物、农业或农药产品、食品添加剂或家用化学品。