ProSpec-IL 8 Human (1-77) His,CHM-345

ProSpec-IL 8 Human (1-77) His,CHM-345,白细胞介素 8 是一种由巨噬细胞和其他细胞类型(如上皮细胞)产生的趋化因子。 它也由内皮细胞合成,内皮细胞将 IL-8 储存在它们的储存囊泡 Weibel-Palade 体中。

  • IL 8 Human , His

  • Interleukin-8 Human Recombinant , His Tag
  • CHM-345

Catalogue number

CHM-345

Synonyms

IL-8, CXCL8, Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil-activating peptide, MONAP, Emoctakin, K60, NAF, LECT, LUCT, 3-10C, LYNAP, SCYB8, TSG-1, AMCF-I, b-ENAP.

Introduction

Interleukin-8 is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. When first encountering an antigen, the primary cells to encounter it are the macrophages who phagocytose the particle. Upon processing, they release chemokines to signal other immune cells to come in to the site of inflammation. IL-8 is one such chemokine. It serves as a chemical signal that attracts neutrophils at the site of inflammation, and therefore is also known as Neutrophil Chemotactic Factor.
白细胞介素 8 是一种由巨噬细胞和其他细胞类型(如上皮细胞)产生的趋化因子。 它也由内皮细胞合成,内皮细胞将 IL-8 储存在它们的储存囊泡 Weibel-Palade 体中。 当第一次遇到抗原时,遇到它的原代细胞是吞噬颗粒的巨噬细胞。 在处理后,它们会释放趋化因子以向其他免疫细胞发出信号,使其进入炎症部位。 IL-8 就是这样一种趋化因子。 它作为一种化学信号,在炎症部位吸引中性粒细胞,因此也称为中性粒细胞趋化因子。

Description

Interleukin-8 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 77 amino acids fragment and having a total molecular mass of 13.7kDa with an amino-terminal hexahistidine tag.
The IL-8 His is purified by proprietary chromatographic techniques.
在大肠杆菌中产生的白细胞介素 8 人重组体是单一的、非糖基化的多肽链,包含 77 个氨基酸片段,总分子量为 13.7kDa,带有氨基末端六组氨酸标签。
IL-8 His 通过专有的色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered clear solution.

Formulation

IL8 His is supplied in 10mM Tris-HCl pH 8, 250mM NaCl and 50% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.

Purity

Greater than 95.0% as determined by -PAGE.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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