标签： ProSpec-IFNW1 Human

IFN omega-1, IFN alpha-II-1, IFNW1.

IFN-Omega 1 is a type I IFN, that can be induced by virus-infected leukocytes. Type I IFN family members, which include IFN-alpha, IFN-beta, and IFN-omega, signal through IFNAR-1/IFNAR-2 receptor complex, and wield antiviral and antiproliferative activities. IFNW1 exhibits about 75% sequence homology with IFN-a, and contains 2 conserved disulfide bonds, which are essential for full biological activity.

IFN-Omega 1 是一种 I 型 IFN，可被病毒感染的白细胞诱导。 I 型 IFN 家族成员，包括 IFN-α、IFN-β 和 IFN-omega，通过 IFNAR-1/IFNAR-2 受体复合物发出信号，并具有抗病毒和抗增殖活性。 IFNW1 与 IFN-a 具有约 75% 的序列同源性，并含有 2 个保守的二硫键，这对于完全的生物活性是必不可少的。

IFN-Omega 1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 172 amino acids and having a molecular mass of 19.9kDa.
The IFN-Omega 1 is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 IFN-Omega 1 Human Recombinant 是一种单一的、非糖基化的多肽链，含有 172 个氨基酸，分子量为 19.9kDa。
IFN-Omega 1 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

It is recommended to reconstitute the lyophilized IFNW1 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

建议在不低于 100µg/ml 的无菌 18M-cm H2O 中复溶冻干的 IFNW1，然后可以进一步稀释成其他水溶液。

Lyophilized IFNW1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFNW1 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

冻干的 IFNW1 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。 重构后，IFNW1 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Greater than 95.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

MCDLPQNHGL LSRNTLVLLH QMRRISPFLC LKDRRDFRFP QEMVKGSQLQ KAHVMSVLHE MLQQIFSLFH TERSSAAWNM TLLDQLHTGL HQQLQHLETC LLQVVGEGES AGAISSPALT LRRYFQGIRV YLKEKKYSDC AWEVVRMEIM KSLFLSTNMQ ERLRSKDRDL GSS.

The ED₅₀ was determined by a cytotoxicity assay using Human TF-1 cells is < 0.01 ng/ml, corresponding to a specific activity of > 100,000,000 units/mg.

使用人 TF-1 细胞通过细胞毒性测定确定 ED50 为 < 0.01 ng/ml，对应于 > 100,000,000 单位/mg 的比活性。

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。