ProSpec-IFN b Mouse, His/CYT-651

ProSpec-IFN b Mouse His,ProSpec CYT-651,ProSpec代理,ProSpec产品,ProSpec产品目录,ProSpec Cytokines,细胞内细菌和胞质多聚在不同的人类细胞中触发 IFN-β 反应,而不需要人类 ZBP1。

IFN b Mouse, His
IFN Beta Mouse Recombinant, His Tag
CYT-651
ProSpec-IFN b Mouse, His/CYT-651 5µg
ProSpec-IFN b Mouse, His/CYT-651 25µg
ProSpec-IFN b Mouse, His/CYT-651 1mg

Catalogue number

CYT-651

Synonyms

Leukocyte IFN, B cell IFN, Type I IFN, IFNB1, IFB, IFF, IFNB, IFN-b 1b, MGC96956.

Introduction

IFN-beta 1b has antiviral, antibacterial and anticancer activities.
Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via mechanism involving induction of the SOCS-3 protein.
Intracellular bacteria and cytosolic poly trigger IFN-beta responses in different human cells without requiring human ZBP1.

IFN-beta 1b 具有抗病毒、抗菌和抗癌活性。
甲型流感病毒不仅抑制 IFN-β 基因诱导,而且通过涉及 SOCS-3 蛋白诱导的机制抑制 I 型 IFN 信号传导。
细胞内细菌和胞质多聚在不同的人类细胞中触发 IFN-β 反应,而不需要人类 ZBP1。

Description

IFN beta Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids and having a molecular mass of 22 kDa. Mouse IFN beta is fused to 21 amino acid at N-terminus and purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 IFN beta Mouse Recombinant 是一种单一的、非糖基化的多肽链,含有 182 个氨基酸,分子量为 22 kDa。 小鼠 IFN β 在 N 末端与 21 个氨基酸融合,并通过专有色谱技术进行纯化。

Source

Escherichia Coli.

Physical Appearance

Sterile filtered colorless solution.

Formulation

The IFN-Beta contains 20mM HEPES , 0.5M NaCl, 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 95% as determined by Analysis by -PAGE.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN.

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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