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GRO-g/CINC-2b Rat
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GRO-gamma, CINC-2 beta Rat Recombinant
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CHM-273
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Catalogue number
CHM-273
Synonyms
Macrophage inflammatory protein 2-beta, MIP2-beta, CXCL3, Growth-regulated protein gamma, GRO-gamma, GRO-gamma , GRO3, GROg, MIP2B, SCYB3, MIP-2b, CINC-2b, MGSA gamma.
Introduction
Chemokine ligand 3 is a small cytokine belonging to the CXC chemokine family that is also known as GRO3 oncogene , GRO protein gamma and macrophage inflammatory protein-2-beta . CXCL3 controls migration and adhesion of monocytes and mediates it effects on its target cell by interacting with a cell surface chemokine receptor called CXCR2. The gene for CXCL3 is located on chromosome 4 in a cluster of other CXC chemokines.
趋化因子配体 3 是属于 CXC 趋化因子家族的小细胞因子,也称为 GRO3 癌基因、GRO 蛋白 γ 和巨噬细胞炎症蛋白-2-β。 CXCL3 控制单核细胞的迁移和粘附,并通过与称为 CXCR2 的细胞表面趋化因子受体相互作用介导其对靶细胞的影响。 CXCL3 基因位于其他 CXC 趋化因子簇中的 4 号染色体上。
Description
GRO-g Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 68 amino acids and having a total molecular mass of 7.8kDa.
GRO-g is purified by proprietary chromatographic techniques.
GRO-g is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
Lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.
Solubility
It is recommended to reconstitute the lyophilized GRO-g in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability
Lyophilized GRO-g although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GRO-g should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.
冻干的 GRO-g 虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 复溶后,GRO-g 应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。
对于长期储存,建议添加载体蛋白。
请防止冻融循环。
对于长期储存,建议添加载体蛋白。
请防止冻融循环。
Purity
Greater than 97.0% as determined by
Analysis by RP-HPLC.
Analysis by -PAGE.
Analysis by RP-HPLC.
Analysis by -PAGE.
Amino acid sequence
RELRCQCLKT LPRVDFENIQ SLTVTPPGPH CTQTEVIATL KDGQEVCLNP QAPRLQKIIQ KLLKSPSL.
Biological Activity
Determined by its ability to chemoattract human CXCR2 transfected 293 cells using a concentration range of 10-100ng/ml.
Usage
Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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