标签： ProSpec-GRO b Rat

Macrophage inflammatory protein 2-alpha, MIP2-alpha, CXCL2, Growth- regulated protein beta, Gro-beta, chemokine ligand 2, GRO2, GROb, MIP2, MIP2A, SCYB2, MGSA-b, MIP-2a, CINC-2a, MGSA beta, CINC-3.

趋化因子配体 2 是属于 CXC 趋化因子家族的一种小细胞因子，也称为巨噬细胞炎症蛋白 2-α、生长调节蛋白 β 和 Gro oncogene-2。 CXCL2 在氨基酸序列上与相关趋化因子 CXCL1 有 90% 相同。 这种趋化因子由单核细胞和巨噬细胞分泌，对多形核白细胞和造血干细胞具有趋化作用。 CXCL2 的基因位于人类 4 号染色体上的其他 CXC 趋化因子簇中。 CXCL2 通过与称为 CXCR2 的细胞表面趋化因子受体相互作用来动员细胞。

GRO-Beta Rat Recombinant also called Rat MIP-2 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 73 amino acids and having a molecular mass of 7923 Dalton.
The GRO-b is purified by proprietary chromatographic techniques.

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

It is recommended to reconstitute the lyophilized GRO-beta Rat in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Lyophilized GRO-b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL2 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein . Please prevent freeze-thaw cycles.

Greater than 99.0% as determined by -PAGE.

VVVASELRCQ CLTTLPRVDF KNIQSLTVTP PGPHCAQTEV IATLKDGHEV CLNPEAPLVQ RIVQKILNKG KAN.

The biological activity was determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml, corresponding to a specific activity of 100,000-1,000,000 units/mg.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.