Catalogue number
CYT-432
Synonyms
Acrp30, AdipoQ, GBP-28, APM-1, ACDC.
Introduction
Adiponectin is adipocyte complement-related protein of 30 kDa and exclusively expressed in differentiated adipocytes. APM-1 is a member of the complement factor C1q family and consists of signal sequence, Non-homologous sequence, collagen domain and domain .
Adiponectin expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30 Mouse or gAcrp30 lowers serum glucose and free fatty acid level in mice.
Adiponectin expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30 Mouse or gAcrp30 lowers serum glucose and free fatty acid level in mice.
脂联素是 30 kDa 的脂肪细胞补体相关蛋白,仅在分化的脂肪细胞中表达。 APM-1是补体因子C1q家族的成员,由信号序列、非同源序列、胶原结构域和结构域组成。
在人类、猴子和小鼠的各种肥胖和胰岛素抵抗状态下,脂联素的表达降低。 注射 Acrp30 Mouse 或 gAcrp30 可降低小鼠的血清葡萄糖和游离脂肪酸水平。
在人类、猴子和小鼠的各种肥胖和胰岛素抵抗状态下,脂联素的表达降低。 注射 Acrp30 Mouse 或 gAcrp30 可降低小鼠的血清葡萄糖和游离脂肪酸水平。
Description
The globular domain of Adiponectin Mouse Recombinant / Acrp30 Mouse contains 138 amino acid residues from a.a. 111-247 having molecular mass of 16 kDa was over expressed in E.coli and purified by using conventional chromatography techniques.
Adiponectin Mouse Recombinant / Acrp30 Mouse 的球状结构域包含来自 a.a. 的 138 个氨基酸残基。 具有 16 kDa 分子量的 111-247 在大肠杆菌中过表达,并通过使用常规色谱技术进行纯化。
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
Acrp30 Mouse solution containing 20mM Tris-HCl pH7.5, 50mM NaCl, 5mM DTT and 10% Glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用,请在 4°C 下储存。 储存,在 -20°C 下冷冻更长时间。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 95.0% as determined by -PAGE.
Amino acid sequence
MAYMYRSAFS VGLETRVTVP NVPIRFTKIF YNQQNHYDGS TGKFYCNIPG LYYFSYHITVYMKDVKVSLF KKDKAVLFTY DQYQEKNVDQ ASGSVLLHLE VGDQVWLQVY GDGDHNGLYADNVNDSTFTG FLLYHDTN
References
Title: Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death
Publication: Experimental & translational stroke medicine 2.1 : 15.
Link: http://www.etsmjournal.com/content/2/1/15
Publication: Experimental & translational stroke medicine 2.1 : 15.
Link: http://www.etsmjournal.com/content/2/1/15
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。
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