标签： ProSpec-Fractalkine Mouse

Fractalkine, C-X3-C motif chemokine 1, CX3C membrane-anchored chemokine, Neurotactin, Small-inducible cytokine D1, Cx3cl1, Cx3c, Fkn, Scyd1, CX3C, ABCD-3, AB030188, AI848747, D8Bwg0439e.

Fractalkine 可溶形式对 t 细胞和单核细胞具有趋化性，但对中性粒细胞不具有趋化性。 Fractalkine 膜结合形式促进这些白细胞与内皮细胞的粘附。 Fractalkine 调节内皮的白细胞粘附和迁移过程并与 CX3CR1 结合。 Natural Human Fractalkine 是一种长蛋白，具有延伸的粘蛋白样茎和顶部的趋化因子结构域。 粘蛋白样茎允许它与细胞表面结合。 Fractalkine 基因与一些称为 CCL17 和 CCL22 的 CC 趋化因子一起位于人类第 16 号染色体上。

在大肠杆菌中产生的 Fractalkine Mouse Recombinant 是一条单一的、非糖基化的多肽链，包含 76 个氨基酸，分子量为 8.7kDa。
CX3CL1 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

It is recommended to reconstitute the lyophilized CX3CL1 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Lyophilized CX3CL1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CX3CL1 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

QHLGMTKCEI MCGKMTSRIP VALLIRYQLN QESCGKRAIV LETTQHRRFC ADPKEKWVQD AMKHLDHQAA ALTKNG.

The ED₅₀as determined by a cell proliferation assay using human peripheral blood lymphocytes is less than 0.5 µg/ml, corresponding to a specific activity of > 2000IU/mg.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.