标签： ProSpec-Exodus 2 Mouse

ProSpec-Exodus 2 Mouse,Exodus-2 小鼠重组CHM-371

ProSpec-Exodus 2 Mouse,Exodus-2 小鼠重组CHM-371,CCL21 的基因位于人类第 9 号染色体上。CCL21 通过与称为 CCR7 的细胞表面趋化因子受体结合来引发其作用。

  • Exodus 2 Mouse

  • Exodus-2 Mouse Recombinant
  • CHM-371

Catalogue number

CHM-371

Synonyms

Small inducible cytokine A21, CCL21, Beta chemokine exodus-2, 6Ckine, Secondary lymphoid-tissue chemokine, SLC, chemokine ligand 21, ECL, CKb9, TCA4, SCYA21, MGC34555.

Introduction

趋化因子配体 21 是属于 CC 趋化因子家族的小细胞因子。 这种趋化因子也称为 6Ckine、exodus-2 和次级淋巴组织趋化因子。 CCL21 主要在淋巴结中表达，与其他 CC 趋化因子相比，它对淋巴细胞具有趋化性。 CCL21 的基因位于人类第 9 号染色体上。CCL21 通过与称为 CCR7 的细胞表面趋化因子受体结合来引发其作用。

Description

Exodus-2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 110 amino acids and having a molecular mass of 12kDa.
The CCL21 is purified by proprietary chromatographic techniques.

Source

Escherichia Coli.

Physical Appearance

Sterile Filtered White lyophilized powder.

Formulation

Lyophilized from a concentrated solution in water containing 20mM Phosphate buffer and 0.15M NaCl pH-7.4.

Solubility

It is recommended to reconstitute the lyophilized Exodus2 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions

Stability

Lyophilized Exodus-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL21 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein . Please prevent freeze-thaw cycles.

Purity

Greater than 97.0% as determined by -PAGE & RP-HPLC.

Amino acid sequence

SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG.

Biological Activity

Determined  by its ability to chemoattract total murine T cell population using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.

Usage

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

  • Exodus 2 Human
  • Exodus-2 Mouse, Sf9

ProSpec-Exodus-2 Mouse, Sf9,Exodus-2 小鼠重组体，Sf9 CHM-043

ProSpec-Exodus-2 Mouse, Sf9,Exodus-2 小鼠重组体，Sf9 CHM-043,Exodus-2 蛋白或 CCL21 是一种细胞因子，是 CC 趋化因子亚组的一部分。 由于其半胱氨酸氨基酸的6个保守残基，该蛋白质也被命名为6Ckine和SLC。

  • Exodus-2 Mouse, Sf9

  • Exodus-2 Mouse Recombinant, Sf9
  • CHM-043

Catalogue number

CHM-043

Synonyms

Ccl21a, C-C motif chemokine 21a, 6Ckine, Beta-chemokine exodus-2, Small-inducible cytokine A21a,Thymus-derived chemotactic agent 4, TCA4, Ccl21a, Scya21, Scya21a, 6CKBAC2, 6Ckine, ALP,AW987545, CKb9, plt, Scya21b, SLC.

Introduction

Exodus-2 蛋白或 CCL21 是一种细胞因子，是 CC 趋化因子亚组的一部分。 由于其半胱氨酸氨基酸的6个保守残基，该蛋白质也被命名为6Ckine和SLC。 编码这种蛋白质的基因位于人类的第 9 号染色体上。 Exodus-2 与 CCR7 受体结合，这是一种位于细胞表面的趋化因子受体。

Description

在 Sf9 杆状病毒细胞中产生的 Exodus-2 小鼠重组体是一条含有 119 个氨基酸且分子量为 13.1kDa 的糖基化多肽链。
Exodus-2 在 C 末端与 9 个氨基酸的 His 标签融合，并通过专有色谱技术进行纯化。

Source

Sf9, Baculovirus cells.

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The  Exodus-2 solution contains  Phosphate-Buffered Saline and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Purity

Greater than 90.0% as determined by -PAGE.

Amino acid sequence

ADPSDGGGQD CCLKYSQKKI PYSIVRGYRK QEPSLGCPIP AILFSPRKHS KPELCANPEE GWVQNLMRRL DQPPAPGKQS PGCRKNRGTS KSGKKGKGSK GCKRTEQTQP SRGHHHHHH

Usage

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

  • Exodus 2 Human
  • Exodus 2 Mouse