标签： ProSpec-Exodus 2 Human

Small inducible cytokine A21, CCL21, Beta chemokine exodus-2, 6Ckine, Secondary lymphoid-tissue chemokine, SLC, chemokine ligand 21, ECL, CKb9, TCA4, SCYA21, MGC34555.

趋化因子配体 21 是属于 CC 趋化因子家族的小细胞因子。 这种趋化因子也称为 6Ckine、exodus-2 和次级淋巴组织趋化因子。 CCL21 主要在淋巴结中表达，与其他 CC 趋化因子相比，它对淋巴细胞具有趋化性。 CCL21 的基因位于人类第 9 号染色体上。CCL21 通过与称为 CCR7 的细胞表面趋化因子受体结合来引发其作用。

Exodus-2 Human Recombinant 在大肠杆菌中产生，为单一的非糖基化多肽链，包含 111 个氨基酸，分子量为 12219 道尔顿。
CCL21 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Lyophilized from a 0.2µm filtered concentrated solution in 20mM Phosphate Buffer, pH 7.4 and 150mM NaCl.

It is recommended to reconstitute the lyophilized Exodus2 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Lyophilized Exodus-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL21 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG P.

Determined by its ability to chemoattract human total lymphocyte population using a concentration range of 10-100ng/ml.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.