标签： ProSpec EBI3 Macaque

IL-27B, IL27B, IL 27-B, EBI-3, Interleukin-27 beta, IL-27 subunit beta, Epstein-Barr virus-induced gene 3 protein homolog, EBI3.

EBI3 has an induced expression in B lymphocytes in reaction to Epstein-Barr virus infection. EBI3 encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form iIL-27. EBI3 drives rapid clonal expansion of naive cd4 t-cells. EBI3 strongly synergizes with IL-12 to activate IFN-gamma production of naive cd4 t-cells. EBI3 mediates its biologic effects through the cytokine receptor wsx-1/tccr.

EBI3 在对 Epstein-Barr 病毒感染作出反应的 B 淋巴细胞中具有诱导表达。 EBI3 编码一种属于造血素受体家族的分泌糖蛋白，并与 28 kDa 蛋白异二聚化形成 iIL-27。 EBI3 驱动幼稚 cd4 t 细胞的快速克隆扩增。 EBI3 与 IL-12 强烈协同作用以激活幼稚 cd4 t 细胞的 IFN-γ 产生。 EBI3 通过细胞因子受体 wsx-1/tccr 介导其生物学效应。

EBI3 Macaque Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 210 amino acids and having a molecular mass of 23.4kDa. The EBI3 is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 EBI3 Macaque Recombinant 是一条单一的、非糖基化的多肽链，包含 210 个氨基酸，分子量为 23.4kDa。 EBI3 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Lyophilized from a sterile filtered solution containing 0.1 % trifluoroacetic acid .

It is recommended to reconstitute the lyophilized EBI3 in sterile 18MΩ-cm H₂O at a concentration of 100µg/ml, which can then be further diluted to other aqueous solutions.

建议在无菌 18MΩ-cm H2O 中以 100µg/ml 的浓度重构冻干的 EBI3，然后可以将其进一步稀释成其他水溶液。

Lyophilized EBI3 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EBI3 Macaque should be stored at 4°C between 2-7 days and for future use below -18°C.

For long term storage it is recommended to add a carrier protein .

冻干的 EBI3 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。 重新配制后，EBI3 Macaque 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。

对于长期储存，建议添加载体蛋白。

Please prevent freeze-thaw cycles.

Greater than 95.0% as determined by -PAGE.

MRKGPPAALT LPRVQCRAPR YPIAVDCSWT LPPAPNSTSP VSFIATYRFG MAARGHSWPC LQQTPASTSC TIADVRLFSM APYVLNVTAV HPWGSSSSFV PFIAEHIIKP DPPEGVRLSP LAERQLQVQW EPPRSWPFPE IFSLKYWIRY KRQGAARFHQ VGPIEATSFI LRAVRPRARY CVQVAAQDLT DYGELSDWSL PATTPMSPGK.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。