AITR Human
Catalogue number
CYT-925
Synonyms
TNFRSF18, AITR, CD357, GITR, GITR-D, Tumor necrosis factor receptor superfamily member 18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, CD357, UNQ319/PRO364.
Introduction
Tumor necrosis factor receptor superfamily member 18 is a member of the tumor necrosis factor receptor superfamily. AITR is receptor for TNFSF18 and appears to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. AITR is mediates NF-kappa-B activation via the TRAF2/NIK pathway.
肿瘤坏死因子受体超家族成员18是肿瘤坏死因子受体超家族的成员。 AITR 是 TNFSF18 的受体，似乎参与活化的 T 淋巴细胞和内皮细胞之间的相互作用以及 T 细胞受体介导的细胞死亡的调节。 AITR 通过 TRAF2/NIK 通路介导 NF-kappa-B 激活。
Description
AITR Human Recombinant produced in Sf9 Baculovirus is a single, glycosylated polypeptide chain containing 145 amino acids and having a molecular mass of 15.6kDa .
AITR is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
AITR is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒中产生的 AITR 人重组体是一条单一的糖基化多肽链，包含 145 个氨基酸，分子量为 15.6kDa。
AITR 在 C 末端与 8 个氨基酸的 His 标签融合，并通过专有色谱技术进行纯化。
AITR 在 C 末端与 8 个氨基酸的 His 标签融合，并通过专有色谱技术进行纯化。
Source
Sf9, Baculovirus cells.
Physical Appearance
Sterile filtered colorless solution.
Formulation
AITR protein solution containing Phosphate Buffered Saline and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 95.0% as determined by -PAGE.
Amino acid sequence
QRPTGGPGCG PGRLLLGTGT DARCCRVHTT RCCRDYPGEE CCSEWDCMCV QPEFHCGDPC CTTCRHHPCP PGQGVQSQGK FSFGFQCIDC ASGTFSGGHE GHCKPWTDCT QFGFLTVFPG NKTHNAVCVP GSPPAEPLEH HHHHH.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 它们不得用作药物、农业或农药产品、食品添加剂或家用化学品。