标签： ProSpec CYT-812

Apolipoprotein C-I, Apo-CI, ApoC-I, Apolipoprotein C1, APOC1.

Apolipoprotein C-I which expressed mainly in the liver is a part of the apolipoprotein C family. APOC1 which is usually found in plasma and responsible for the activation of esterified lechitin cholesterol takes an important part in the exchange of esterified cholesterol among lipoproteins and in removal of cholesterol from tissues. APOC1 is activated when monocytes differentiate into macrophages. APOC1 protein’s main role is to inhibit CETP by altering the electric charge of HDL molecules. APOC1 is also binds free fatty acids and reduces their intracellular esterification.

主要在肝脏中表达的载脂蛋白C-I是载脂蛋白C家族的一部分。 APOC1 通常存在于血浆中，负责激活酯化卵磷脂胆固醇，在脂蛋白之间的酯化胆固醇交换和从组织中去除胆固醇中起重要作用。 当单核细胞分化为巨噬细胞时，APOC1 被激活。 APOC1蛋白的主要作用是通过改变HDL分子的电荷来抑制CETP。 APOC1 还结合游离脂肪酸并减少它们的细胞内酯化。

APOC1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 80 amino acids and having a molecular mass of 9.0kDa. APOC1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 APOC1 Human Recombinant 是一条含有 80 个氨基酸且分子量为 9.0kDa 的单一非糖基化多肽链。 APOC1 在 N 端与 23 个氨基酸的 His 标签融合，并通过专有色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered clear solution.

APOC1 protein solution contains 20mM Tris-HCl buffer , 0.15M NaCl and 10% glycerol.

APOC1 蛋白溶液含有 20mM Tris-HCl 缓冲液、0.15M NaCl 和 10% 甘油。

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Greater than 90% as determined by -PAGE.

MGSSHHHHHH SSGLVPRGSH MGSTPDVSSA LDKLKEFGNT LEDKARELIS RIKQSELSAK MREWFSETFQ KVKEKLKIDS.

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