标签： ProSpec CYT-706

Fms-related tyrosine kinase 3 ligand, FLK2, STK1, CD135, Stem Cell Tyrosine Kinase 1, FLT3LG, Flt3.

FLT3 ligand is a receptor for the fl cytokine has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation.

FLT3 配体是 fl 细胞因子的受体，具有酪氨酸蛋白激酶活性和调节早期造血细胞增殖的生长因子。 Flt3-配体与其他脑脊液和白细胞介素协同作用以诱导生长和分化。

Flt3-Ligand Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 24-30kDa due to glycosylation. The Flt3-Ligand is purified by proprietary chromatographic techniques.

在 HEK 细胞中产生的 Flt3-Ligand Human Recombinant 是一种糖基化单体，由于糖基化，其分子量范围为 24-30kDa。 Flt3-Ligand 通过专有的色谱技术进行纯化。

HEK293 .

Sterile Filtered White lyophilized powder.

Flt3-Ligand was lyophilized from a 0.2µm filtered solution containing 1xPBS.

It is recommended to reconstitute the lyophilized Flt3-Ligand in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

建议在不低于 100µg/ml 的无菌 18MΩ-cm H2O 中复溶冻干的 Flt3-Ligand，然后可以进一步稀释成其他水溶液。

Lyophilized Flt3-Ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Flt3-Ligand should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein . Please prevent freeze-thaw cycles.

冻干的 Flt3-Ligand 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。 复溶后，Flt3-Ligand 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。 对于长期储存，建议添加载体蛋白。 请防止冻融循环。

Greater than 95.0% as determined by: Analysis by RP-HPLC. Analysis by -PAGE.

TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTAPQP.

The activity was determined by the dose- dependent stimulation of the proliferation of the human acute myeloid leukemia cell line OCI-AML5. The ED₅₀ is 0.56ng/ml.

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