标签： ProSpec CYT-668

Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein, EBV-induced gene 3 protein, EBI3, IL27B.

EBI3 has an induced expression in B lymphocytes in reaction to Epstein-Barr virus infection. EBI3 encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form iIL-27. EBI3 drives rapid clonal expansion of naive cd4 t-cells. EBI3 strongly synergizes with IL-12 to activate IFN-gamma production of naive cd4 t-cells. EBI3 mediates its biologic effects through the cytokine receptor wsx-1/tccr.

EBI3 在对 Epstein-Barr 病毒感染作出反应的 B 淋巴细胞中具有诱导表达。 EBI3 编码一种属于造血素受体家族的分泌糖蛋白，并与 28 kDa 蛋白异二聚化形成 iIL-27。 EBI3 驱动幼稚 cd4 t 细胞的快速克隆扩增。 EBI3 与 IL-12 强烈协同作用以激活幼稚 cd4 t 细胞的 IFN-γ 产生。 EBI3 通过细胞因子受体 wsx-1/tccr 介导其生物学效应。

EBI3 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 209 amino acids fragment having a molecular weight of 34kDa and fused with a 4.5kDa amino-terminal hexahistidine tag.
The EBI3 is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 EBI3 Human Recombinant 是一个单一的、非糖基化的多肽链，包含 209 个氨基酸片段，分子量为 34kDa，并与 4.5kDa 氨基末端六组氨酸标签融合。
EBI3 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered clear solution.

EBI3 protein is supplied in 1xPBS, 50% glycerol.

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
Please avoid freeze thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。
储存，在 -20°C 下冷冻更长时间。
请避免冻融循环。

Greater than 95.0% as determined by -PAGE.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。