标签： ProSpec CYT-615

Acrp30, AdipoQ, GBP-28, APM-1, ACDC.

gAcrp30 globular protein, exists as a result of proteolytic processing of adiponectin. Adiponectin is manufactured and secreted solely by adipocytes, and is a highly obtained plasma protein, accounting for up to 0.05% of total serum protein. Similar to Adiponectin, gAcrp30 is able of lowering hyperglycemia and reversing INS resistance. In addition, gAcrp30 is an significant protein that is involved in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids. AdipoR1 & AdipoR2 are the 2 signaling receptors for adiponectin and gAcrp30 that were recently been identified.

gAcrp30 球状蛋白是脂联素蛋白水解加工的结果。 脂联素仅由脂肪细胞制造和分泌，是一种高度获得的血浆蛋白，占血清总蛋白的0.05%。 与脂联素类似，gAcrp30 能够降低高血糖并逆转 INS 抗性。 此外，gAcrp30 是一种重要的蛋白质，它通过向肌肉发出信号以吸收和燃烧游离脂肪酸来促进脂肪减少。 AdipoR1 和 AdipoR2 是最近发现的脂联素和 gAcrp30 的 2 个信号受体。

gAcrp30 Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 145 amino acids and having a molecular mass of 16.7kDa.
The gAcrp30 is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 gAcrp30 Human Recombinant 是一种非糖基化的多肽链，含有 145 个氨基酸，分子量为 16.7kDa。
gAcrp30 通过专有的色谱技术进行纯化。

Escherichia Coli.

 

We recommended reconstituting gAcrp30 at a concentration of 0.1mg per ml with 10mM sodium phosphate & 0.5mM DTT, pH 7.5. which can then be further diluted to other aqueous solutions.

我们建议使用 10mM 磷酸钠和 0.5mM DTT，pH 7.5 以 0.1mg/ml 的浓度重构 gAcrp30。 然后可以进一步稀释成其他水溶液。

For long term, store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
Reconstituted protein can be stored at 4°C for a limited period of time two weeks.

长期保存冻干蛋白在-20°C。 重组后分装产品以避免重复的冷冻/解冻循环。
重构的蛋白质可以在 4°C 下储存两周的有限时间。

Greater than 95% as determined by -PAGE.

MKGEPGEGAY VYRSAFSVGL ETYVTIPNMP IRFTKIFYNQ QNHYDGSTGK FHCNIPGLYY FAYHITVYMK DVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEG ERNGLYADND NDSTFTGFLL YHDTN.

gAcrp30 activity is determined by its ability to inhibit the proliferation of mouse M1 cells. The expected ED₅₀ for this effect is 669ng/ml, corresponding to a specific activity of 1.5×10³units/mg.

gAcrp30 的活性取决于其抑制小鼠 M1 细胞增殖的能力。 这种效果的预期 ED50 为 669ng/ml，对应于 1.5x103units/mg 的比活性。

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Prospec 的产品仅供实验室研究使用。 它们不得用作药物、农业或农药产品、食品添加剂或家用化学品。