标签： ProSpec CYT-402

Growth Differentiation Factor 11, GDF-11, Bone Morphogenetic Protein 11, BMP11.

GDF-11 belongs to the bone morphogenetic protein family and the TGF-beta superfamily. GDF-11 is a central developmental factor which controls muscular and neural development. In adults, GDF-11 encourages cardiac hypertrophy reverse by the revival of cardiomyocytes.

GDF-11 属于骨形态发生蛋白家族和 TGF-β 超家族。 GDF-11 是控制肌肉和神经发育的中枢发育因子。 在成人中，GDF-11 通过心肌细胞的恢复促进心脏肥大逆转。

GDF11 Human Recombinant produced in E.Coli is a non-glycosylated homodimer containing 2×109 amino acids and having a total molecular mass of 24.9kDa. 

在大肠杆菌中产生的 GDF11 Human Recombinant 是一种非糖基化同源二聚体，含有 2×109 个氨基酸，总分子量为 24.9kDa。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

It is recommended to reconstitute the lyophilized GDF11 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

建议在不低于 100µg/ml 的无菌 18M-cm H2O 中复溶冻干的 GDF11，然后可以进一步稀释成其他水溶液。

Lyophilized GDF11 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution GDF11 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

冻干的 GDF11 虽然在室温下可稳定保存 3 周，但应在 -18°C 以下干燥储存。 复溶后，GDF11 应在 4°C 下储存 2-7 天，以备将来在 -18°C 以下使用。
对于长期储存，建议添加载体蛋白。
请防止冻融循环。

Greater than 95.0% as determined by -PAGE.

The ED₅₀ as determined by the ability to inhibit alkaline phosphatase activity in ATDC5 cells, is 0.2-0.3ng/ml, corresponding to a specific activity of 5 x 10⁶units/mg.

通过抑制 ATDC5 细胞中碱性磷酸酶活性的能力确定的 ED50 为 0.2-0.3ng/ml，对应于 5 x 106units/mg 的比活性。

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