标签： ProSpec CYT-1191

Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, OX-40L, CD252, Tnfsf4, Ox40l, Txgp1l, gp3, OX4, Ath-1, Ath1, CD134L, gp34, Tnlg2b, Txgp1l

肿瘤坏死因子配体超家族成员 4、OX40 配体、OX40L、OX-40L、CD252、Tnfsf4、Ox40l、Txgp1l、gp3、OX4、Ath-1、Ath1、CD134L、gp34、Tnlg2b、Txgp1l

OX40 Ligandis a part of the tumor necrosis factor receptor family. OX40L receptor is OX40 which is expressed predominantly on activated CD4+ T cells.OX40 Ligandis expressed on various antigen-presenting cells such asmacrophages, DC2sand activated Blymphocytes. Expression of OX40 is momentary following engagement of T cell receptors. The ligation of OX40-OX40L stimulates proliferation anddifferentiation of activated B cells,increases immunoglobulin secretion and is also a sourceof survival signal for T cells and enables the development of memory T cells.

OX40 配体是肿瘤坏死因子受体家族的一部分。 OX40L受体是主要在活化的CD4+ T细胞上表达的OX40。OX40配体在各种抗原呈递细胞如巨噬细胞、DC2和活化的淋巴细胞上表达。 OX40 的表达是 T 细胞受体结合后的瞬间。 OX40-OX40L的连接刺激活化B细胞的增殖和分化，增加免疫球蛋白分泌，也是T细胞生存信号的来源，使记忆T细胞发育成为可能。

OX40L Mouse produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 157 amino acids and having a molecular mass of 17.7kDa.
OX40L  is fused to a 6 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.

在 Sf9 杆状病毒细胞中产生的 OX40L 小鼠是一条糖基化多肽链，包含 157 个氨基酸，分子量为 17.7kDa。
OX40L 在 C 端与 6 个氨基酸的 His 标签融合，并通过专有色谱技术进行纯化。

Sf9, Baculovirus cells.

Sterile filtered colorless solution.

The OX40L solution contains 10% Glycerol and Phosphate-Buffered Saline .

Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。
储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Greater than 90.0% as determined by -PAGE.

Determined by its binding ability in a functional ELISA with Human TNFRSF4 .

ADPSSSPAKD PPIQRLRGAV TRCEDGQLFI SSYKNEYQTM EVQNNSVVIK CDGLYIIYLK GSFFQEVKID LHFREDHNPI SIPMLNDGRR IVFTVVASLA FKDKVYLTVN APDTLCEHLQ INDGELIVVQ LTPGYCAPEG SYHSTVNQVP LHHHHHH

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

ProSpec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。