Resistin Human Recombinant, HEK
CYT-1183
2µg
10µg
1mg
Catalogue number
CYT-1183
Synonyms
RETN,ADSF,FIZZ3,RETN1,RSTN,XCP1,resistin precursor, Adipose tissue-specific secretory factor, ADSFMGC126609, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, FIZZ3; FIZZ3MGC126603, found in inflammatory zone 3, HXCP1.
Introduction
Resistin, also known as adipose tissue-specific secretory factor is a cysteine-rich peptide derived from adipose tissue. Resistin takes part in the inflammatory response, glucose metabolism, and angiogenesis.Resistin blocks insulinstimulated uptake of glucose by adipocytes and promote glucose release by hepatocytes. As such,Resistin considered to participate in diet‑induced insulin-sensitivity. Resistin causes high levels of lowdensity lipoprotein , increasing the risk of heart disease.
抵抗素,也称为脂肪组织特异性分泌因子,是一种来源于脂肪组织的富含半胱氨酸的肽。 抵抗素参与炎症反应、葡萄糖代谢和血管生成。抵抗素阻断胰岛素刺激的脂肪细胞摄取葡萄糖并促进肝细胞释放葡萄糖。 因此,抵抗素被认为参与了饮食诱导的胰岛素敏感性。 抵抗素会导致高水平的低密度脂蛋白,增加患心脏病的风险。
Description
Resistin Human Recombinant produced in HEK293 cells is a single, glycosylated polypeptide chain containing 96 amino acids and having a molecular mass of 10.3 kDa.
Resistin is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
在 HEK293 细胞中产生的 Resistin Human Recombinant 是单条糖基化多肽链,含有 96 个氨基酸,分子量为 10.3 kDa。
抵抗素在 C 末端与 6 个氨基酸的 His 标签融合,并通过专有色谱技术进行纯化。
Source
HEK293 cells.
Physical Appearance
Formulation
Resistin protein contains 20% glycerol and 20mM Sodium citrate .
Stability
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by -PAGE.
Amino acid sequence
KTLCSMEEAI NERIQEVAGS LIFRAISSIG LECQSVTSRG DLATCPRGFA VTGCTCGSAC GSWDVRAETT CHCQCAGMDW TGARCCRVQP HHHHHH
Usage
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