NT-proBNP Human
NT-Pro-B-type Natriuretic Protein Human Recombinant
CYT-1118
ProSpec-NT-proBNP Human/CYT-1118 10µg
ProSpec-NT-proBNP Human/CYT-1118 50µg
ProSpec-NT-proBNP Human/CYT-1118 1mg
Catalogue number
CYT-1118
Synonyms
NPPB, Natriuretic Peptide Precursor B, BNP, B-type Natriuretic Peptide.
Introduction
Natriuretic Peptide Precursor B acts as a cardiac hormone with a variety of biological actions including natriuresis,vasorelaxation,diuresis and inhibition of renin and aldosterone secretion. BNP plays a key role in cardiovascular homeostasis. BNP also helps restore the body’s salt and water balance andimproves heart function.
利钠肽前体 B 作为一种心脏激素,具有多种生物作用,包括利钠、血管舒张、利尿以及抑制肾素和醛固酮的分泌。 BNP 在心血管稳态中起关键作用。 BNP 还有助于恢复身体的盐和水平衡并改善心脏功能。
Description
NT-Pro-B-type Natriuretic Protein Human Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 76 amino acid and having a molecular mass of approximately 8.5kDa.
NT-proBNP is purified by proprietary chromatographic techniques.
NT-Pro-B-type Natriuretic Protein Human Recombinant 在大肠杆菌中产生,是一种非糖基化多肽链,含有 76 个氨基酸,分子量约为 8.5kDa。
NT-proBNP 通过专有的色谱技术进行纯化。
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH 8.0 and 150mM NaCl.
从 20mM Tris-HCl、pH 8.0 和 150mM NaCl 中的 0.2μm 过滤浓缩溶液冻干。
Solubility
It is recommended to reconstitute the lyophilized NT-Pro-B-type Natriuretic Protein in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
建议将冻干的 NT-Pro-B 型利钠蛋白在不低于 100µg/ml 的无菌 18MΩ-cm H2O 中复溶,然后可以进一步稀释成其他水溶液。
Stability
Lyophilized NT-proBNP although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution NT-Pro-B-type Natriuretic Protein should be stored at 4°C between 2-7 days and for future use below -18°C.
冻干的 NT-proBNP 虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 重构后,NT-Pro-B 型利尿钠蛋白应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。
Please prevent freeze-thaw cycles.
Purity
Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.
Amino acid sequence
HPLGSPGSAS DLETSGLQEQ RNHLQGKLSE LQVEQTSLEP LQESPRPTGV WKSREVATEG IRGHRKMVLY TLRAPR.
Usage
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