TNFRSF21 Human
CYT-1073
ProSpec-TNFRSF21 Human/CYT-1073 2µg
ProSpec-TNFRSF21 Human/CYT-1073 10µg
ProSpec-TNFRSF21 Human/CYT-1073 1mg
Catalogue number
CYT-1073
Synonyms
Tumor necrosis factor receptor superfamily member 21, BM-018, CD358, DR6, Death receptor 6.
Introduction
Tumor necrosis factor receptor superfamily member 21 or TNFRSF21, is a protein that located in the cell membrane from the TNF receptor superfamily. By activating the NF-kappaB pathway, TNFRSF21 promotes cell apoptosis. The degeneration of cells caused by activating caspase 3 and caspase 6, the TNFRSF21 binds to the N-terminal APP in neuronal cell bodies and axons which leads to apoptosis. TNFRSF21 takes part in signaling cascades activated by stimulation of T-cell receptor.
肿瘤坏死因子受体超家族成员 21 或 TNFRSF21，是一种位于 TNF 受体超家族细胞膜中的蛋白质。 通过激活 NF-kappaB 通路，TNFRSF21 促进细胞凋亡。 由激活 caspase 3 和 caspase 6 引起的细胞变性，TNFRSF21 与神经元细胞体和轴突中的 N 端 APP 结合，导致细胞凋亡。 TNFRSF21 参与由 T 细胞受体刺激激活的信号级联。
Description
TNFRSF21 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 547 amino acids and having a molecular mass of 60.4kDa. .
TNFRSF21 is expressed with a 239 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒细胞中产生的 TNFRSF21 是单条糖基化多肽链，含有 547 个氨基酸，分子量为 60.4kDa。 .
TNFRSF21 在 C 末端用 239 个氨基酸 His 标签表达，并通过专有色谱技术进行纯化。
Source
Sf9, Baculovirus cells.
Physical Appearance
Sterile filtered colorless solution.
Formulation
TNFRSF21 protein solution contains phosphate buffered saline ,10% glycerol and 0.1 mM PMSF.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks.
Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。
储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
Avoid multiple freeze-thaw cycles.
Purity
Greater than 85.0% as determined by -PAGE.
Amino acid sequence
QPEQKASNLI GTYRHVDRAT GQVLTCDKCP AGTYVSEHCT NTSLRVCSSC PVGTFTRHEN GIEKCHDCSQ PCPWPMIEKL PCAALTDREC TCPPGMFQSN ATCAPHTVCP VGWGVRKKGT ETEDVRCKQC ARGTFSDVPS SVMKCKAYTD CLSQNLVVIK PGTKETDNVC GTLPSFSSST SPSPGTAIFP RPEHMETHEV PSSTYVPKGM NSTESNSSAS VRPKVLSSIQ EGTVPDNTSS ARGKEDVNKT LPNLQVVNHQ QGPHHRHILK LLPSMEATGG EKSSTPIKGP KRGHPRQNLH KHFDINEHLE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG KHHHHHH.