IFNG Human, His Active
CYT-1053
ProSpec-IFNG Human, His Active/CYT-1053 2µg
ProSpec-IFNG Human, His Active/CYT-1053 10µg
ProSpec-IFNG Human, His Active/CYT-1053 1mg
Catalogue number
CYT-1053
Synonyms
Immune Interferon, type II interferon, T cell interferon, MAF, IFNG, IFG, IFI, IFN-gamma.
Introduction
IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.
IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
由特定抗原或有丝分裂原激活的淋巴细胞产生的 IFN-γ。
IFN-γ除具有抗病毒活性外,还具有重要的免疫调节功能,是巨噬细胞的强效激活剂,对转化细胞具有抗增殖作用,并能增强I型干扰素的抗病毒和抗肿瘤作用。
Description
IFNG Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 159 amino acids and having a molecular mass of 18.4kDa. IFNG is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 IFNG Human Recombinant 是一个单一的、非糖基化的多肽链,包含 159 个氨基酸,分子量为 18.4kDa。 IFNG 在 N 末端与 21 个氨基酸的 His-tag 融合,并通过专有色谱技术进行纯化。
Source
Physical Appearance
Formulation
IFNG protein solution containing Phosphate buffered saline and 20% glycerol.
Stability
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
对于长期储存,建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 90.0% as determined by -PAGE.
Biological Activity
Measured in a cytotoxicity assay using WiDr cells. The ED50 for this effect is ≤ 5 ng/ml.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFRG.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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