TNFRSF10D Human
CYT-1045
ProSpec-TNFRSF10D Human/CYT-1045 1µg
ProSpec-TNFRSF10D Human/CYT-1045 5µg
ProSpec-TNFRSF10D Human/CYT-1045 50µg
Catalogue number
CYT-1045
Synonyms
Tumor necrosis factor receptor superfamily member 10D, CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor 4, TRAIL receptor with a truncated death domain.
Introduction
TRAIL Receptor-4 Human Recombinant or TNFRSF10D, is part of the TNF-receptor superfamily. TNFRSF10D has atruncated cytoplasmic death domai , an extracellular TRAIL-binding domain and a transmembrane domain. The protein can prevent from TRAIL-mediated apoptosis on cells with TRAIL R1 and/or TRAIL R2.
TRAIL Receptor-4 Human Recombinant 或 TNFRSF10D，是 TNF 受体超家族的一部分。 TNFRSF10D 具有截短的细胞质死亡结构域、细胞外 TRAIL 结合结构域和跨膜结构域。 该蛋白质可以防止具有 TRAIL R1 和/或 TRAIL R2 的细胞发生 TRAIL 介导的细胞凋亡。
Description
TNFRSF10D produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 395 amino acids and having a molecular mass of 73.8kDa. .
TNFRSF10D is expressed with a 239 amino acid hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques.
在 Sf9 杆状病毒细胞中产生的 TNFRSF10D 是单条糖基化多肽链，包含 395 个氨基酸，分子量为 73.8kDa。 .
TNFRSF10D 在 C 末端用 239 个氨基酸的 hIgG-His 标签表达，并通过专有色谱技术进行纯化。
Source
Physical Appearance
Formulation
TNFRSF10D protein solution contains phosphate buffered saline and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 90.0% as determined by -PAGE.
Biological Activity
Measured in a neutralizing assay using Jurkat human T lymphocyte. The ED50 for this effect is less or equal to 10 ng/ml in the presence of 2ng/ml TRAIL.
Amino acid sequence
ATIPRQDEVP QQTVAPQQQR RSLKEEECPA GSHRSEYTGA CNPCTEGVDY TIASNNLPSC LLCTVCKSGQ TNKSSCTTTR DTVCQCEKGS FQDKNSPEMC RTCRTGCPRG MVKVSNCTPR SDIKCKNESA ASSTGKTPAA EETVTTILGM LASPYHVEPK SCDKTHTCPP CPAPELLGGP
SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ
QGNVFSCSVM HEALHNHYTQ KSLSLSPGKH HHHHH.