CTF2P Mouse
Neuropoietin Mouse Recombinant
CYT-1128
ProSpec-CTF2P Mouse/CYT-1128 50µg
ProSpec-CTF2P Mouse/CYT-1128 100µg
ProSpec-CTF2P Mouse/CYT-1128 1mg
Catalogue number
CYT-1128
Synonyms
Cardiotrophin-2, CT-2, Neuropoietin, Np, Ctf2, Gm494.
Introduction
CTF2P, aka Neuropoietinis a part of the IL-6 family of cytokines. CTF2P is the outcome of a gene duplication event involving cardiotrophin-1 and it helps to define a subfamily within the IL-6 family that includes CT-1, CLC and CTNF. CTF2P Increases the platelet count associated with splenomegaly and takes part in neuronal precursor development and maturation.
CTF2P,又名 Neuropoietinis,是 IL-6 细胞因子家族的一部分。 CTF2P 是涉及心肌营养因子-1 的基因复制事件的结果,它有助于在 IL-6 家族中定义一个亚家族,包括 CT-1、CLC 和 CTNF。 CTF2P 增加与脾肿大相关的血小板计数并参与神经元前体发育和成熟。
Description
Neuropoietin Mouse Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 182 amino acids and having a molecular mass of approximately 19.7kDa.
CTF2P is purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 Neuropoietin Mouse Recombinant 是一种非糖基化多肽链,含有 182 个氨基酸,分子量约为 19.7kDa。
CTF2P 通过专有的色谱技术进行纯化。
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris-HCl, pH 8.0, 0.5mM DTT and 500mM NaCl.
Solubility
It is recommended to reconstitute the lyophilized Neuropoietin in sterile PBS not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
建议将冻干的神经生成素在不低于 100μg/ml 的无菌 PBS 中复溶,然后可以进一步稀释成其他水溶液。
Stability
Lyophilized CTF2P although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Neuropoietin should be stored at 4°C between 2-7 days and for future use below -18°C.
冻干的 CTF2P 虽然在室温下可稳定保存 3 周,但应在 -18°C 以下干燥储存。 重构后,Neuropoietin 应在 4°C 下储存 2-7 天,以备将来在 -18°C 以下使用。
Please prevent freeze-thaw cycles.
Purity
Greater than 98.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.
Amino acid sequence
APISPSEPIG QAYSLALYMQ KNTSALLQTY LQHQGSPFSD PGFSAPELQL STLPSAAVSF KTWHAMEDAE RLSRAQGAFL ALTQHLQLVG DDQSYLNPGS PILLAQLGAA RLRAQGLLGN MAAIMTALGL PIPPEEDTLG FVPFGASAFE RKCRGYIVTR EYGHWTDRAV RDLALLKAKY SA.
Biological Activity
The ED50 as determined by a cell proliferation assay using human TF-1 cells is < 200 ng/ml, corresponding to a specific activity of > 5000 IU/mg.