标签： ProSpec BST2 Human

Bone marrow stromal cell antigen 2, CD317 antigen, BST-2, HM1.24 antigen, Tetherin,
NPC-A-7.

BST2 takes part in the growth and development of B-cells. The human cellular protein BST2 inhibits retrovirus infection by maintaining the diffusion of virus particles after budding from infected cells. BST2 was originally discovered as an inhibitor to HIV-1 infection in the absence of Vpu, but it is also known to inhibit the release of other viruses such as the Lassa and Marburg virions. In addition, BST2 has a part in B-cell activation in rheumatoid arthritis.

BST2 参与 B 细胞的生长和发育。 人类细胞蛋白 BST2 通过在受感染细胞出芽后维持病毒颗粒的扩散来抑制逆转录病毒感染。 BST2 最初被发现是在没有 Vpu 的情况下作为 HIV-1 感染的抑制剂，但也已知它可以抑制其他病毒的释放，例如 Lassa 和 Marburg 病毒粒子。 此外，BST2 在类风湿性关节炎中参与 B 细胞活化。

BST2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 133 amino acids and having a molecular mass of 14.8 kDa.
The BST2 is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 BST2 Human Recombinant 是单条非糖基化多肽链，包含 133 个氨基酸，分子量为 14.8 kDa。
BST2 在 N 末端与 21 个氨基酸的 His-Tag 融合，并通过专有色谱技术进行纯化。

Escherichia Coli.

BST2 is supplied as a sterile filtered clear solution.

BST2 protein 0.5mg/ml is supplied in 20mM Tris-HCl, pH-8, 0.1M NaCl, 1mM DTT and 20% Glycerol.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Greater than 80.0% as determined by -PAGE.

MGSSHHHHHH SSGLVPRGSH MSEACRDGLR AVMECRNVTH LLQQELTEAQ KGFQDVEAQA ATCNHTVMAL MASLDAEKAQ GQKKVEELEG EITTLNHKLQ DASAEVERLR RENQVLSVRI ADKKYYPSSQ DSS

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Prospec 的产品仅供实验室研究使用。 该产品不得用作药物、农业或农药产品、食品添加剂或家用化学品。