标签： ProSpec BST1 Human

Bone Marrow Stromal Cell Antigen 1, ADP-Ribosyl Cyclase 2, Bone Marrow Stromal Antigen 1, Cyclic ADP-Ribose Hydrolase 2, NAD Nucleosidase, CADPr Hydrolase 2, ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2, CD157 Antigen, EC 3.2.2.6, CD157, BST-1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, ADP-ribosyl cyclase 2, Bone marrow stromal antigen 1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2.

骨髓基质细胞抗原 1、ADP-核糖基环化酶 2、骨髓基质抗原 1、环状 ADP-核糖水解酶 2、NAD 核苷酶、CADPr 水解酶 2、ADP-核糖基环化酶/环状 ADP-核糖水解酶 2、CD157 抗原、EC 3.2 .2.6、CD157、BST-1、ADP-核糖基环化酶/环状 ADP-核糖水解酶 2、ADP-核糖基环化酶 2、骨髓基质抗原 1、环状 ADP-核糖水解酶 2、cADPr 水解酶 2。

BST1 , is a GPI anchored membrane protein which is part of the CD38 family. BST1 was initially recognized as a bone marrow stromal cell molecule. BST1 is an ectoenzyme sharing more than a few features with ADP-ribosyl cyclase CD38. BST1 together with CD38, exhibit both DP-ribosyl cyclase and cyclinc ADP ribose hydrolase activities. BST1 participates in rheumatoid arthritis due to its enhanced expression in RA-derived bone marrow stromal cell lines. Moreover, BST1 is expressed by cells of the myeloid lineage and could perform as a receptor with a signal transduction capability.

BST1 是一种 GPI 锚定膜蛋白，它是 CD38 家族的一部分。 BST1 最初被认为是一种骨髓基质细胞分子。 BST1 是一种与 ADP-核糖基环化酶 CD38 共享多个特征的外酶。 BST1 与 CD38 一起表现出 DP-核糖基环化酶和 cyclinc ADP 核糖水解酶活性。 BST1 参与类风湿性关节炎，因为它在 RA 衍生的骨髓基质细胞系中表达增强。 此外，BST1 由髓系细胞表达，可以作为具有信号转导能力的受体发挥作用。

BST1 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 267 amino acids and having a molecular mass of 30.5kDa. .
BST1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

在 Sf9 杆状病毒细胞中产生的 BST1 是单条糖基化多肽链，包含 267 个氨基酸，分子量为 30.5kDa。 .
BST1 在 C 末端用 6 个氨基酸的 His 标签表达，并通过专有色谱技术进行纯化。

Sf9, Baculovirus cells.

Sterile filtered colorless solution.

BST1 protein solution contains 10% glycerol & Phosphate Buffered Saline .

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。

Greater than 95.0% as determined by -PAGE.

RWRGEGTSAH LRDIFLGRCA EYRALLSPEQ RNKNCTAIWE AFKVALDKDP CSVLPSDYDL FINLSRHSIP RDKSLFWENS HLLVNSFADN TRRFMPLSDV LYGRVADFLS WCRQKNDSGL DYQSCPTSED CENNPVDSFW KRASIQYSKD SSGVIHVMLN GSEPTGAYPI KGFFADYEIP NLQKEKITRI EIWVMHEIGG PNVESCGEGS MKVLEKRLKD MGFQYSCIND YRPVKLLQCV DHSTHPDCAL KSAAAATQRK AHHHHHH.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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