APOH Human
Apolipoprotein-H Human
PRO-552
ProSpec-APOH Human/PRO-552 100µg
ProSpec-APOH Human/PRO-552 1mg
ProSpec-APOH Human/PRO-552 5mg
Catalogue number
PRO-552
Synonyms
Beta-2-glycoprotein 1, Beta-2-glycoprotein I, Apolipoprotein H, Apo-H, B2GPI, BetaGPI, Activated protein C-binding protein, APC inhibitor, Anticardiolipin cofactor, APOH, B2G1, BG, B2GP-1, B2 Glycoprotein-I.
Beta-2-糖蛋白 1、Beta-2-糖蛋白 I、载脂蛋白 H、Apo-H、B2GPI、BetaGPI、活化蛋白 C 结合蛋白、APC 抑制剂、抗心磷脂辅因子、APOH、B2G1、BG、B2GP-1、B2 糖蛋白 -一世。
Introduction
Apolipoprotein H attaches to numerous kinds of negatively charged substances for instance heparin, phospholipids, and dextran sulfate. APOH prevents activation of the intrinsic blood coagulation cascade by attaching to phospholipids on the surface of damaged cells. APOH expressed by the liver and secreted in the plasma.
载脂蛋白 H 附着在多种带负电荷的物质上,例如肝素、磷脂和硫酸葡聚糖。 APOH 通过附着在受损细胞表面的磷脂上来防止内在凝血级联反应的激活。 APOH由肝脏表达并分泌到血浆中。
Description
Human APOH produced in Human Plasma having a molecular mass of 50kDa and pI of 5.6-6.4. It’s a major phospholipid binding protein and an important component to measure in the assessment of anti-phospholipid syndrome. APOH is also more specific than anti-cardiolipin antibodies and its presence correlates better with thrombotic risk.
人血浆中产生的人 APOH,分子量为 50kDa,pI 为 5.6-6.4。 它是一种主要的磷脂结合蛋白,也是评估抗磷脂综合征的重要成分。 APOH 也比抗心磷脂抗体更具特异性,其存在与血栓形成风险的相关性更好。
Source
Human Plasma.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
Lyophilized from 0.02M NH4HCO3.
Solubility
It is recommended to reconstitute the lyophilized APOH in phosphate buffer, pH >7.0 containing 0.15M NaCl.
Stability
Human APOH although stable at room temperature for 3 weeks, should be stored between 2-8°C.
Purity
Greater than 96.0%.
Human Virus Test
Starting material tested and found negative for HIV I & II antibodies, Hepatitis B surface antigen, and Hepatitis C antibodies.
对起始材料进行测试,发现 HIV I 和 II 抗体、乙型肝炎表面抗原和丙型肝炎抗体呈阴性。
Usage
Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec 的产品仅供实验室研究使用。 它们不得用作药物、农业或农药产品、食品添加剂或家用化学品。
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