标签： ProSpec ANGPTL4 Human

ANGPTL4, NL2, ARP4, FIAF, PGAR, HFARP, pp1158, ANGPTL2, Fasting- Induced Adipose Factor, Hepatic Fibrinogen/Angiopoietin-Related Protein, PPARG Angiopoietin-Related Protein.

ANGPTL4、NL2、ARP4、FIAF、PGAR、HFARP、pp1158、ANGPTL2、空腹诱导脂肪因子、肝纤维蛋白原/血管生成素相关蛋白、PPARG 血管生成素相关蛋白。

FIAF a.k.a ANGPTL4 or PGAR or HFARP is an adipocytokine up-regulated by fasting, by peroxisome proliferator-activated receptor agonists, and by hypoxia. ANGPTL4 is found in human and mouse blood plasma both as a native protein and in a truncated form. In human white adipose tissue and SGBS adipocytes, only the native form of ANGPTL4 could be detected, whereas in mice the differentiation of mouse 3T3-L1 adipocytes is associated with the production of truncated ANGPTL4. However, the truncated ANGPTL4 is produced by human liver. In human blood plasma FIAF is mainly presented in a truncated form , whose levels treatment increases . There is an inter individual variation in ANGPTL4 levels of both the truncated and the native form, however those levels were not influenced by prolonged semistarvation and are not associated with body mass index.

FIAF a.k.a ANGPTL4 或 PGAR 或 HFARP 是一种通过禁食、过氧化物酶体增殖物激活受体激动剂和缺氧上调的脂肪细胞因子。 ANGPTL4 以天然蛋白质和截短形式存在于人和小鼠血浆中。 在人类白色脂肪组织和 SGBS 脂肪细胞中，只能检测到天然形式的 ANGPTL4，而在小鼠中，小鼠 3T3-L1 脂肪细胞的分化与截短 ANGPTL4 的产生有关。 然而，截短的 ANGPTL4 是由人肝脏产生的。 在人血浆中，FIAF 主要以截短形式呈现，其水平治疗增加。 截断和天然形式的 ANGPTL4 水平存在个体间差异，但这些水平不受长期半饥饿的影响，并且与体重指数无关。

The ANGPTL4 Human Recombinant is manufactured with N-terminal fusion of His Tag.
The Angiopoietin-like Protein 4 His -Tagged Fusion Protein is 25 kDa protein containing 204 amino acid residues of the Angiopoietin-like Protein 4 and 16 additional amino acid residues – His Tag .

ANGPTL4 Human Recombinant 是用 His 标签的 N 端融合制造的。
血管生成素样蛋白 4 His-Tagged 融合蛋白是 25 kDa 的蛋白质，含有血管生成素样蛋白 4 的 204 个氨基酸残基和 16 个额外的氨基酸残基 – His Tag。

Escherichia Coli.

Greater than 95% as determined by -PAGE.

Filtered White lyophilized powder.

Filtered and lyophilized from 0.5 mg/ml in 0.05M Acetate buffer pH-4.

Add 0.1M Acetate buffer pH4 and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10μg/ml. In higher concentrations the solubility of this antigen is limited.

加入 0.1M 醋酸缓冲液 pH4，让冻干颗粒完全溶解。 为了转化为更高的 pH 值，我们建议使用相关缓冲液将其充分稀释至 10μg/ml 的浓度。 在较高浓度下，该抗原的溶解度是有限的。

Store lyophilized Angiopoietin-like Protein 4 Human recombinant at -20°C. Aliquot the ANGPTL4 after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted ANGPTL4 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.

将冻干的血管生成素样蛋白 4 人重组体储存在 -20°C。 重组后分装 ANGPTL4，以避免重复冷冻/解冻循环。 重构的 ANGPTL4 可以在 4°C 下储存一段有限的时间； 在 4°C 下两周后它没有显示任何变化。

MRGSHHHHHH GMASHMGPVQ SKSPRFASWD EMNVLAHGLL QLGQGLREHA ERTRSQLSAL ERRLSACGSA CQGTEGSTDL PLAPESRVDP EVLHSLQTQL KAQNSRIQQL FHKVAQQQRH LEKQHLRIQH LQSQFGLLDH KHLDHEVAKP ARRKRLPEMA QPVDPAHNVS RLHRLPRDCQ ELFQVGERQS GLFEIQPQGS PPFLVNCKMT SDGGWTVIQR.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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