PEG3-Dicarboxylic acid

PEG3-Dicarboxylic acid,PEG3-二羧酸是一种同型双功能接头,在 PEG3 分子的两侧具有两个羧酸基团。

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PEG3-Dicarboxylic acid

标签:Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
1715-1g 1 g 490.00$ in stock
1715-5g 5 g 890.00$ in stock
1715-10g 10 g 1370.00$ in stock

PEG3-Dicarboxylic acid is a homobifunctional linker with two carboxylic acid groups flanking the PEG3 molecule.

The linker is highly hydrophilic and useful for the conjugation and immobilization of proteins, peptides, and other biomolecules. The carboxy groups can be activated by carbodiimides.
PEG3-二羧酸是一种同型双功能接头,在 PEG3 分子的两侧具有两个羧酸基团。

该接头具有高度亲水性,可用于蛋白质、肽和其他生物分子的缀合和固定。 羧基可以被碳二亚胺活化。

PEG3-Dicarboxylic acid PEG3-Dicarboxylic acid PEG3-Dicarboxylic acid PEG3-Dicarboxylic acid

PEG3-Dicarboxylic acid相关产品

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

Alkyne-PEG3-COOH

Bifunctional linker with terminal alkyne function, and carboxylic acid moiety, CAS# 1415800-32-6.

具有末端炔烃功能和羧酸部分的双功能接头,CAS# 1415800-32-6。

Azide-PEG3-Amine

A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)

具有叠氮化物和胺基的双功能接头,位于 PEG3(三甘醇)的两侧

General properties

Molecular weight: 294.3
CAS number: 31127-85-2
Molecular formula: C12H22O8
IUPAC name: 3-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]propanoic acid, 4,7,10,13-tetraoxahexadecanedioic acid
Solubility: good in water and polar organic solvents
Quality control: NMR 1H
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Iodo-PEG3-Iodide

Iodo-PEG3-Iodide,PEG3 二碘化物是一种具有两个碘化物官能团的同型双功能接头,对许多亲核试剂如硫醇、胺、烷氧基阴离子等具有很强的反应性。可用于合成亲水性对称偶联物。

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Iodo-PEG3-Iodide

标签:PEG3 (triethylene glycol), Halogenides, Iodides
货号 规格 价格 货期
2098-1g 1 g 290.00$ in stock

PEG3 diiodide is a homobifunctional linker with two iodide functional groups which are very reactive against many nucleophiles like thiols, amines, alkoxy anions, etc. Can be used to synthesize hydrophilic symmetrical conjugates.

PEG3 二碘化物是一种具有两个碘化物官能团的同型双功能接头,对许多亲核试剂如硫醇、胺、烷氧基阴离子等具有很强的反应性。可用于合成亲水性对称偶联物。

Iodo-PEG3-Iodide Iodo-PEG3-Iodide Iodo-PEG3-Iodide Iodo-PEG3-Iodide

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Iodo-PEG3-Acid

A bifunctional compound containing carboxylic acid functional group, and iodide, an active halogen group.

一种含有羧酸官能团和碘化物、活性卤素基团的双官能化合物。

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

Iodo-PEG3-Azide

Iodo-PEG3-Azide is a bifunctional linker with a highly reactive alkylative halogen functional group, and an azido group for Click chemistry / Staudinger ligation.

Iodo-PEG3-Azide 是一种双功能接头,具有高反应性烷基化卤素官能团和用于 Click chemistry / Staudinger ligation 的叠氮基。

General properties

Appearance: yellow-brown oil
Molecular weight: 369.97
CAS number: 36839-55-1
Molecular formula: C6H12I2O2
IUPAC name: 1,2-bis(2-iodoethoxy)ethane
Solubility: soluble in water, polar organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

Azide-PEG3-Carboxylic acid

Azide-PEG3-Carboxylic acid,Azide-PEG3-Carboxylic acid 是一种具有末端羧基和叠氮基的双功能接头。这种分子是亲水的,适合合成水溶性结合物。

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Azide-PEG3-Carboxylic acid

标签:Azides,Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
2558-1g 1 g 265.00$ in stock
2558-5g 5 g 950.00$ in stock
Azide-PEG3-Carboxylic acid is a bifunctional linker with terminal carboxyl and azido groups.

This molecule is hydrophilic and suitable for the synthesis of water-soluble conjugates.

The azide group can enter into [3+2]-dipolar cycloaddition reactions with biomolecules containing an alkyne moiety (Click Chemistry reactions), and the carboxyl group can be activated and react with various amines.

The repertoire of the synthesized bioconjugates can be very broad; for example, different antibody-drug conjugates (ADC) can be generated using this approach. Also, the conjugation of a PEG linker to a molecule can increase its stability and solubility in water, as well as reduce the immunogenicity.

Azide-PEG3-Carboxylic acid 是一种具有末端羧基和叠氮基的双功能接头。这种分子是亲水的,适合合成水溶性结合物。

叠氮基可以与含有炔烃部分的生物分子发生[3+2]-偶极环加成反应(点击化学反应),羧基可以被活化并与各种胺反应。

合成的生物偶联物的库可以非常广泛; 例如,可以使用这种方法生成不同的抗体-药物偶联物 (ADC)。 此外,PEG 接头与分子的缀合可以增加其在水中的稳定性和溶解度,并降低免疫原性。

Azide-PEG3-Carboxylic acid Azide-PEG3-Carboxylic acid Azide-PEG3-Carboxylic acid Azide-PEG3-Carboxylic acid

Azide-PEG3-Carboxylic acid相关产品

Alkyne-PEG3-COOH

Bifunctional linker with terminal alkyne function, and carboxylic acid moiety, CAS# 1415800-32-6.

具有末端炔烃功能和羧酸部分的双功能接头,CAS# 1415800-32-6。

Azide-PEG3-OH

Azide-PEG3-OH is a bifunctional molecule with azide group, primary alcohol, and a hydrophilic linker in between.

叠氮化物-PEG3-OH 是一种双功能分子,具有叠氮基、伯醇和介于两者之间的亲水性接头。

Alkyne-PEG3-amine

Alkyne PEG3 amine is a medium length heterobifunctional linker for the conjugation.

炔烃 PEG3 胺是用于缀合的中等长度异双功能接头。

General properties

Appearance: colorless liquid
Molecular weight: 247.25
CAS number: 1056024-94-2
Molecular formula: C9H17N3O5
IUPAC name: 3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanoic acid
Solubility: good in water and most organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。

MSDS: Download
Product specifications

Azide-PEG3-Azide

Azide-PEG3-Azide,PEG3(三甘醇)二叠氮化物(1,8-diazido-3,6-dioxaoctane)是一种对称的双功能交联剂,带有两个叠氮基。

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Azide-PEG3-Azide

标签:Azides,Click chemistry,PEG3 (triethylene glycol),Cross linking reagents
货号 规格 价格 货期
207-1g 1 g 95.00$ in stock
207-5g 5 g 390.00$ in stock
207-25g 25 g please inquire in stock
PEG3 (triethylene glycol) diazide (1,8-diazido-3,6-dioxaoctane) is a symmetrical bifunctional crosslinker bearing two azide groups.
PEG3(三甘醇)二叠氮化物(1,8-diazido-3,6-dioxaoctane)是一种对称的双功能交联剂,带有两个叠氮基。

Azide-PEG3-Azide Azide-PEG3-Azide Azide-PEG3-Azide > Azide-PEG3-Azide

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Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

含有炔基和酰肼官能团的双功能试剂。 它与醛和酮反应。 然后炔基可以通过CuAAC反应与各种叠氮化物偶联。

Azide-PEG3-Amine

A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)

PEG3-Dicarboxylic acid

PEG3-Ddicarboxylic acid is a bifunctional linker carrying two carboxy groups. It contains a polyethyleneglycol-3 linker between the carboxyls.

PEG3-D二羧酸是一种带有两个羧基的双功能接头。 它在羧基之间包含一个聚乙二醇-3 接头。

General properties

Appearance: colorless/yellowish liquid
Molecular weight: 200.2
CAS number: 59559-06-7
Molecular formula: C6H12N6O2
IUPAC name: 1,8-diazido-3,6-dioxaoctane, 1,2-bis(2-azidoethoxy)ethane
Solubility: good in water and most organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。 干燥。

MSDS: Download
Product specifications

相关文献:

  1. Hull, S.M.; Lindsay, C.D.; Brunel, L.G.; Shiwarski, D.J.; Tashman, J.W.; Roth, J.G.; Myung, D.; Feinberg, A.W.; Heilshorn, S.C. 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks. Advanced Functional Materials, 2021, 31(7), 2007983. doi: 10.1002/adfm.202007983
  2. Tolentino, M.Q.; Hartmann, A.K.; Loe, D.T.; Rouge, J.L. Controlled release of small molecules and proteins from DNA-surfactant stabilized metal organic frameworks. Journal of Materials Chemistry B, 2020, 8(26), 5627–5635. doi: 10.1039/d0tb00767f

Azide-PEG3-Amine

Azide-PEG3-Amine,叠氮化物-PEG3-胺是一种双功能试剂,具有叠氮基团和位于三甘醇两侧的胺基团。 该接头可用于羧基衍生物(通过胺基的酰化)与炔烃(通过点击化学反应)的缀合。

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Azide-PEG3-Amine

标签:Azides,Amines,Click chemistry,PEG3 (triethylene glycol),Cross linking reagents
货号 规格 价格 货期
218-1g 1 g 95.00$ in stock
218-5g 5 g 280.00$ in stock
218-25g 25 g please inquire in stock
Azide-PEG3-amine is a bifunctional reagent with an azide group, and an amine group flanking triethylene glycol. This linker is useful for the conjugation of carboxylic derivatives (by acylation of the amine group) with alkynes (via a Click chemistry reaction).
叠氮化物-PEG3-胺是一种双功能试剂,具有叠氮基团和位于三甘醇两侧的胺基团。 该接头可用于羧基衍生物(通过胺基的酰化)与炔烃(通过点击化学反应)的缀合。

Azide-PEG3-Amine Azide-PEG3-Amine Azide-PEG3-Amine Azide-PEG3-Amine

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Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

PEG3-Dicarboxylic acid

PEG3-Ddicarboxylic acid is a bifunctional linker carrying two carboxy groups. It contains a polyethyleneglycol-3 linker between the carboxyls.

PEG3-D二羧酸是一种带有两个羧基的双功能接头。 它在羧基之间包含一个聚乙二醇-3 接头。

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

General properties

Appearance: colorless/yellowish oil
Molecular weight: 174.2
CAS number: 166388-57-4
Molecular formula: C6H14N4O2
IUPAC name: 1-Amino-8-azido-3,6-dioxaoctane
Solubility: good in water and most organic solvents
Quality control: NMR 1H, GCMS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。 干燥。

MSDS: Download
Product specifications

Amine-PEG3-carboxylic acid, hydrochloride

Amine-PEG3-carboxylic acid, hydrochloride,胺-PEG3-羧酸是一种含有末端羧基和氨基的双功能PEG3衍生物。 亲水性 PEG3 间隔物易溶于水。

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Amine-PEG3-carboxylic acid, hydrochloride

标签:Amines,Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
2719-1g 1 g 230.00$ in stock
Amine-PEG3-carboxylic acid is a bifunctional PEG3-derivative containing terminal carboxyl and amino groups. Hydrophilic PEG3 spacer is freely soluble in water.

The terminal amino group can react with activated esters, carbonyl compounds, and carbonic acids, e.g. in reductive amination reactions.

The carbonyl group in amine-PEG3-carboxylic acid can react with primary amino groups in the presence of activators (carbodiimides or HATU) resulting in a stable amide bond.

胺-PEG3-羧酸是一种含有末端羧基和氨基的双功能PEG3衍生物。 亲水性 PEG3 间隔物易溶于水。

末端氨基可与活化酯、羰基化合物和碳酸反应,例如 在还原胺化反应中。

胺-PEG3-羧酸中的羰基可在活化剂(碳二亚胺或 HATU)存在下与伯氨基反应,形成稳定的酰胺键。

Amine-PEG3-carboxylic acid, hydrochloride Amine-PEG3-carboxylic acid, hydrochloride Amine-PEG3-carboxylic acid, hydrochloride Amine-PEG3-carboxylic acid, hydrochloride

Amine-PEG3-carboxylic acid, hydrochloride相关产品

Alkyne-PEG3-amine

Alkyne PEG3 amine is a medium length heterobifunctional linker for the conjugation.

炔烃 PEG3 胺是用于缀合的中等长度异双功能接头。

Azide-PEG3-Carboxylic acid

Bifunctional triethylene glycol with terminal carboxyl and azido groups.

具有末端羧基和叠氮基的双官能三甘醇。

General properties

Appearance: yellowish oil
Molecular weight: 257.71
CAS number: 127457-79-8
Molecular formula: C9H20NClO5
IUPAC name: 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]propanoic acid;hydrochloride
Solubility: soluble in water
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。

MSDS: Download
Product specifications

Alkyne-PEG3-amine

Alkyne-PEG3-amine,Alkyne-PEG3-amine 是一种基于三甘醇 (PEG3) 支架的异双功能分子。 它含有胺和炔官能团。 前者可以与各种亲电试剂结合。 后者适用于铜催化点击化学和 Sonogashira 偶联。

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Alkyne-PEG3-amine

标签:Alkynes,Amines,PEG3 (triethylene glycol)
货号 规格 价格 货期
425-1g 1 g 195.00$ in stock
425-5g 5 g 580.00$ in stock
Alkyne-PEG3-amine is a heterobifunctional molecule based on triethyleneglycol (PEG3) scaffold. It contains amine and alkyne functional groups. The former can be conjugated with various electrophiles. The latter is suitable for copper catalyzed Click chemistry and Sonogashira coupling.

PEG linkers are hydrophilic linkers of choice for the conjugation of biomolecules.

Alkyne-PEG3-amine 是一种基于三甘醇 (PEG3) 支架的异双功能分子。 它含有胺和炔官能团。 前者可以与各种亲电试剂结合。 后者适用于铜催化点击化学和 Sonogashira 偶联。

PEG接头是生物分子缀合的亲水接头。

Alkyne-PEG3-amine Alkyne-PEG3-amine Alkyne-PEG3-amine Alkyne-PEG3-amine

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Alkyne-PEG3-NHS ester

Bifunctional hyrophilic linker with NHS ester and terminal alkyne functional group based on triethyleneglycol (PEG3).

基于三甘醇 (PEG3) 的具有 NHS 酯和末端炔烃官能团的双功能亲水接头。

Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.

Alkyne-PEG3-OH 是一种基于三甘醇的双功能接头,具有羟基和炔烃片段。

Alkyne-PEG4-Amine

A bifunctional linker molecule containing both terminal alkyne moiety for Click chemistry, and amine group. Contains a long hydrophilic PEG4 arm.

一种双功能连接分子,包含用于点击化学的末端炔烃部分和胺基。 包含一个长的亲水性 PEG4 臂。

General properties

Appearance: colorless/yellowish liquid
Molecular weight: 187.24
CAS number: 932741-19-0
Molecular formula: C9H17NO3
Solubility: mixable with water, good in polar organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Alkyne-PEG3-OH

Alkyne-PEG3-OH,炔烃 PEG3 OH(单炔丙基三甘醇)是一种基于双功能 PEG3 的接头,具有炔烃和 OH 基团。 它可用于将炔基添加到各种分子中,以用于随后的点击化学应用。

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Alkyne-PEG3-OH

标签:Alkynes,PEG3 (triethylene glycol)
货号 规格 价格 货期
418-1g 1 g 95.00$ in stock
418-5g 5 g 280.00$ in stock
418-25g 25 g please inquire in stock
Alkyne PEG3 OH (mono-propargyl triethylene glycol) is a bifunctional PEG3 based linker with both an alkyne and an OH group. It can be used to add alkyne groups to various molecules for subsequent Click chemistry applications.
炔烃 PEG3 OH(单炔丙基三甘醇)是一种基于双功能 PEG3 的接头,具有炔烃和 OH 基团。 它可用于将炔基添加到各种分子中,以用于随后的点击化学应用。

Alkyne-PEG3-OH Alkyne-PEG3-OH Alkyne-PEG3-OH Alkyne-PEG3-OH

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Alkyne maleimide

Maleimide reagent for the attachment of alkyne functional group to proteins, peptides, and other molecules bearing SH (thiol) groups, including cysteine residues.

用于将炔官能团连接到蛋白质、肽和其他带有 SH(硫醇)基团(包括半胱氨酸残基)的分子上的马来酰亚胺试剂。

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

Alkyne hydrazide

Bifunctional reagent containing alkyne group and hydrazide function. It reacts with aldehydes and ketones. Alkyne group can then be coupled with various azides via CuAAC reaction.

含有炔基和酰肼官能团的双功能试剂。 它与醛和酮反应。 然后炔基可以通过CuAAC反应与各种叠氮化物偶联。

General properties

Appearance: colorless to yellow oil
Molecular weight: 188.22
CAS number: 208827-90-1
Molecular formula: C9H16O4
IUPAC name: 2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethanol, 3,6,9-trioxadodecyne-11-ol-1
Solubility: good in most organic solvents and water
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。 干燥。

MSDS: Download
Product specifications

Alkyne-PEG3-COOH

Alkyne-PEG3-COOH,Alkyne-PEG3-COOH 是一种带有羧基和炔烃部分的双功能三甘醇衍生物。 前者可以用肽偶联试剂(如 PyBOP)或碳二亚胺(如 EDC)活化,与胺形成稳定的酰胺键。 炔基可以在 CuAAc 反应中与叠氮化物偶联。

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Alkyne-PEG3-COOH

标签:Alkynes,Carboxylic acids,PEG3 (triethylene glycol)
货号 规格 价格 货期
1743-1g 1 g 490.00$ in stock
1743-5g 5 g 980.00$ in stock
1743-25g 25 g please inquire in stock
Alkyne-PEG3-COOH is a bifunctional triethyleneglycol derivative bearing a carboxy group, and an alkyne moiety. The former can be activated with peptide coupling reagents like PyBOP or carbodiimides like EDC to form a stable amide linkage with amines. The alkyne group can be coupled with azides in a CuAAc reaction.

PEGs are hydrophilic linkers that are useful in the synthesis of water soluble conjugates.

Alkyne-PEG3-COOH 是一种带有羧基和炔烃部分的双功能三甘醇衍生物。 前者可以用肽偶联试剂(如 PyBOP)或碳二亚胺(如 EDC)活化,与胺形成稳定的酰胺键。 炔基可以在 CuAAc 反应中与叠氮化物偶联。

PEG是可用于合成水溶性缀合物的亲水性接头。

Alkyne-PEG3-COOH Alkyne-PEG3-COOH Alkyne-PEG3-COOH Alkyne-PEG3-COOH

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Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 is a water-soluble Cyanine5 dye alkyne for Click chemistry.

Sulfo-Cy5 是一种用于 Click 化学的水溶性 Cy5 染料炔烃。

Azide-PEG4-Amine

PEG4 amine azide (CAS# 134179-38-7) is a bifunctional linker with amine and azide functional groups. It is based on a tetraethyleneglycol core. The length of the PEG4 linker is 1.4 nm.

PEG4 amine azide (CAS# 134179-38-7) 是一种具有胺和叠氮化物官能团的双功能接头。 它基于四甘醇核心。 PEG4 接头的长度为 1.4 nm。

Cyanine5 carboxylic acid

Cyanine5 carboxylic acid, unactivated dye.

Cy5羧酸,未活化染料。

General properties

Appearance: colorless to yellow oil
Molecular weight: 246.26
CAS number: 1415800-32-6
Molecular formula: C11H18O6
IUPAC name: 3,6,9,12-tetraoxapentadecyn-15-oic acid
Solubility: good in most organic solvents and water
Quality control: NMR 1H, GC-MS (95%, as Me ester)
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

相关文献:

  1. Petrov, R.A.; Mefedova, S.R.; Yamansarov, E.Y.; Maklakova, S.Y.; Grishin, D.A.; Lopatukhina, E.V.; Burenina, O.Y.; Lopukhov, A.V.; Kovalev, S.V.; Timchenko, Y.V.; Ondar, E.E.; Ivanenkov, Y.A.; Evteev, S.A.; Vaneev, A.N.; Timoshenko, R.V.; Klyachko, N.L.; Erofeev, A.S.; Gorelkin, P.V.; Beloglazkina, E.K.; Majouga, A.G. New Small-Molecule Glycoconjugates of Docetaxel and GalNAc for Targeted Delivery to Hepatocellular Carcinoma. Molecular Pharmaceutics, 2021, 18(1), 461–468. doi: 10.1021/acs.molpharmaceut.0c00980

Iodo-PEG3-Azide

Iodo-PEG3-Azide,Iodo-PEG3-Azide 含有一个高反应性的碘化物官能团,可以烷基化各种 C-、O-、N-、S-中心和其他亲核试剂。

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Iodo-PEG3-Azide

标签:Azides, PEG3 (triethylene glycol), Halogenides, Iodides
货号 规格 价格 货期
2163-1g 1 g 290.00$ in stock
2163-5g 5 g 590.00$ in stock
2163-25g 25 g 2490.00$ in stock

Iodo-PEG3-Azide contains a highly reactive iodide functional group which can alkylate a variety of C-, O-, N-, S-centered and other nucleophiles.

Organic iodides are roughly an order of magnitude more active than bromides, and four orders of magnitude more active than chlorides in SN2 reactions. This means that the same alkylation will take 10x less time with iodide than with bromide. Therefore, this molecule helps to effect very fast alkylation.

PEG3 is a moderately long hydrophilic linker. The azide group participates in Click chemistry reactions. It is also easily reduced to an amine group.

Iodo-PEG3-Azide 含有一个高反应性的碘化物官能团,可以烷基化各种 C-、O-、N-、S-中心和其他亲核试剂。

在 SN2 反应中,有机碘化物的活性大约比溴化物高一个数量级,比氯化物高四个数量级。 这意味着使用碘化物进行相同的烷基化反应所需的时间比使用溴化物的时间少 10 倍。 因此,这种分子有助于实现非常快速的烷基化。

PEG3 是中等长度的亲水接头。 叠氮基参与点击化学反应。 它也很容易被还原为胺基。

Iodo-PEG3-Azide相关产品

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物,用于与反式环辛烯和其他应变烯烃的 TCO 连接。

PEG3-tetrazine

PEG3 tetrazine is a mono-reactive triethyleneglycol with a tetrazine group for ied-DA conjugation with strained olefins.

PEG3 四嗪是一种具有四嗪基团的单反应性三甘醇,用于与应变烯烃的 ied-DA 缀合。

Iodo-PEG3-Acid

A bifunctional compound containing carboxylic acid functional group, and iodide, an active halogen group.

一种含有羧酸官能团和碘化物、活性卤素基团的双官能化合物。

General properties

Appearance: colorless to yellow oil 无色至黄色油状物
Molecular weight: 285.08
CAS number: 1309457-01-9
Molecular formula: C6H12N3IO2
IUPAC name: 1-(2-azidoethoxy)-2-(2-iodoethoxy)ethane
Solubility: soluble in water, polar organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 干燥。

MSDS: Download
Product specifications

Chloro-PEG3-Azide

Chloro-PEG3-Azide,Chloro-PEG3-Azide 是一种异双功能接头,带有用于烷基化各种亲核基团的反应性氯化物。 由于氧的非嵌合辅助,该原子比正常的烷基氯化物更具反应性。 另一个反应基团是叠氮化物。 它可以通过点击化学结合,或还原为胺基,然后与反应性羰基化合物进行酰化。

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Chloro-PEG3-Azide

标签:Azides, PEG3 (triethylene glycol), Halogenides
货号 规格 价格 货期
2106-1g 1 g 490.00$ 21 days

Chloro-PEG3-Azide is a heterobifunctional linker bearing a reactive chloride for the alkylation of various nucleophilic groups. Due to anchimeric assistance from oxygen, this atom is more reactive than in normal alkyl chlorides. The other reactive group is azide. It can be conjugated via Click chemistry, or reduced to amine group to be later acylated with reactive carbonyl compounds.

PEG3 is a versatile hydrophilic linker for bioconjugation.

Chloro-PEG3-Azide 是一种异双功能接头,带有用于烷基化各种亲核基团的反应性氯化物。 由于氧的非嵌合辅助,该原子比正常的烷基氯化物更具反应性。 另一个反应基团是叠氮化物。 它可以通过点击化学结合,或还原为胺基,然后与反应性羰基化合物进行酰化。

PEG3 是用于生物偶联的多功能亲水接头。

Chloro-PEG3-Azide相关产品

Azide-PEG3-Amine

A bifunctional linker with azide and amine groups flanking PEG3 (triethylene glycol)

具有叠氮化物和胺基的双功能接头,位于 PEG3(三甘醇)的两侧

Iodo-PEG3-Iodide

Homobifunctional PEG3 based linker with halogen reactive groups is useful for the crosslinking of nucleophiles.

具有卤素反应基团的基于同双功能 PEG3 的接头可用于亲核试剂的交联。

Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.

Alkyne-PEG3-OH 是一种基于三甘醇的双功能接头,具有羟基和炔烃片段。

General properties

Appearance: colorless oil 无色油
Molecular weight: 193.63
Molecular formula: C6H12N3ClO2
IUPAC name: 1-(2-Azidoethoxy)-2-(2-chloroethoxy)ethane
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Biotin-PEG3-Azide

Biotin-PEG3-Azide,生物素叠氮化物是与叠氮基共价结合的生物素(维生素 H)的衍生物。 该试剂允许用生物素标记各种炔基化分子(如 DNA、寡核苷酸和蛋白质)。 与亲和素或链霉亲和素结合的生物素可用于下游亲和应用,以分离生物素化分子或它们与链霉亲和素缀合物的结合。

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Biotin-PEG3-Azide

标签:Azides, PEG3 (triethylene glycol)
货号 规格 价格 货期
C3730 10 mg 40.00$ in stock
D3730 25 mg 90.00$ in stock
E3730 50 mg 140.00$ in stock
F3730 100 mg 180.00$ in stock

Biotin azide is a derivative of biotin (vitamin H) covalently bound with azide group. This reagent allows labeling of various alkynylated molecules (such as DNA, oligonucleotides, and proteins) with biotin. Biotin binding to avidin or streptavidin can be used in downstream affinity applications for the isolation of biotinylated molecules or their binding with streptavidin conjugates.

This structure of biotin azide features long hydrophilic linker which separates biotin residue from the target molecule for efficient binding with streptavidin. Its linker (PEG) also enhances aqueous solubility to facilitate conjugation.

The azide can be conjugated with various molecules using our recommended protocol.

生物素叠氮化物是与叠氮基共价结合的生物素(维生素 H)的衍生物。 该试剂允许用生物素标记各种炔基化分子(如 DNA、寡核苷酸和蛋白质)。 与亲和素或链霉亲和素结合的生物素可用于下游亲和应用,以分离生物素化分子或它们与链霉亲和素缀合物的结合。

生物素叠氮化物的这种结构具有长的亲水性接头,可将生物素残基与靶分子分开,从而与链霉亲和素有效结合。 它的接头 (PEG) 还增强了水溶性以促进结合。

使用我们推荐的方案,叠氮化物可以与各种分子结合。

Biotin-PEG3-Azide相关产品

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

PEP azide

PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for Click-Chemistry labeling.

PEP(苯乙炔基芘),用于 Click-Chemistry 标记的多环芳烃荧光染料。

Cyanine3.5 azide

Cyanine3.5 azide for biomolecule labeling through Click Chemistry.

通过 Click Chemistry 用于生物分子标记的 Cy3.5 叠氮化物。

General properties

Appearance: colorless solid 无色固体
Molecular weight: 400.50
CAS number: 945633-30-7
Molecular formula: C16H28N6O4S
Solubility: soluble in DMF, DMSO, moderately soluble in water
Quality control: NMR 1H (95%) and 13C, TLC, functional testing
Storage conditions: Storage: 24 months after receival at -20°C. Transportation: at room temperature for up to 3 weeks.

储存:-20°C 收货后 24 个月。 运输:在室温下长达 3 周。

MSDS: Download
Product specifications

相关文献:

  1. Dettling, S.E.; Ahmadi, M.; Lin, Z.; He, L.; Matthews, M.L. Discovery of Electrophiles and Profiling of Enzyme Cofactors. Current Protocols in Chemical Biology, 2020, 12(4), e86. doi: 10.1002/cpch.86
  2. Wang, Y.; Dattmore, D.A.; Wang, W:; Pohnert, G.; Wolfram, S.; Zhang, J.; Yang, R.; Decker, E.A.; Lee, K.S.S.; Zhang, G. trans, trans-2,4-decadienal, a lipid peroxidation product, induces inflammatory responses via Hsp90- or 14–3-3ζ-dependent mechanisms. Journal of Nutritional Biochemistry, 2020, 76, 108286. doi: 10.1016/j.jnutbio.2019.108286
  3. Shen, Y.; Yang, S.; Hu, X.; Zhang, M.; Ma, X.; Wang, Z.; Hou, Y.; Bai, G. Natural product puerarin activates Akt and ameliorates glucose and lipid metabolism dysfunction in hepatic cells. Journal of Functional Foods, 2019, 55, 296–304. doi: 10.1016/j.jff.2019.02.035
  4. Wang, E.; Hunter, C.P. SID-1 Functions in Multiple Roles To Support Parental RNAi in Caenorhabditis elegans. Genetics, 2017, 207(2), 547–557. doi: 10.1534/genetics.117.300067

Azide-PEG3-OH

Azide-PEG3-OH,储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。具有伯醇官能团、叠氮基和 PEG3 亲水性接头的异双功能交联剂。

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  • Azide-PEG3-OH

Azide-PEG3-OH

标签:Azides, PEG3 (triethylene glycol),Bifunctional crosslinkers
货号 规格 价格 货期
1742-1g 1 g 90.00$ in stock

Heterobifunctional crosslinker with a primary alcohol functional group, azide group, and a PEG3 hydrophilic linker.

具有伯醇官能团、叠氮基和 PEG3 亲水性接头的异双功能交联剂。

Azide-PEG3-OH相关产品

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cyanine5 azide 是一种用 Cyanine5(一种流行的荧光染料)进行 Click Chemistry 标记的试剂。

Iodo-PEG3-Azide

Iodo-PEG3-Azide is a bifunctional linker with a highly reactive alkylative halogen functional group, and an azido group for Click chemistry / Staudinger ligation.

Iodo-PEG3-Azide 是一种双功能接头,具有高反应性烷基化卤素官能团和用于 Click chemistry / Staudinger ligation 的叠氮基。

General properties

Appearance: colorless liquid 无色液体
Molecular weight: 175.19
CAS number: 86520-52-7
Molecular formula: C6H13N3O3
IUPAC name: 2-[2-(2-azidoethoxy)ethoxy]-ethanol
Solubility: miscible with water, most organic solvents
Quality control: NMR 1H, GC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

PEG3-tetrazine

PEG3-tetrazine,储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。PEG3 四嗪是一种单反应性衍生物,可通过反电子需求 Diels-Alder 反应 (ied-DA) 与应变烯烃(例如反式环辛烯和一些环辛炔)轻松连接亲水性三甘醇片段(聚乙二醇化)。

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PEG3-tetrazine

标签:Tetrazine, Copper free Click chemistry, PEG3 (triethylene glycol)
货号 规格 价格 货期
1978-250mg 250 mg 370.00$ in stock
1978-1g 1 g 950.00$ in stock

PEG3 tetrazine is a monoreactive derivative that allows a facile attachment of hydrophilic triethyleneglycol fragment (pegylation) by inverse electron demand Diels-Alder reaction (ied-DA) with strained olefins, such as trans-cyclooctenes, and some cyclooctynes.

PEG3 四嗪是一种单反应性衍生物,可通过反电子需求 Diels-Alder 反应 (ied-DA) 与应变烯烃(例如反式环辛烯和一些环辛炔)轻松连接亲水性三甘醇片段(聚乙二醇化)。

PEG3-tetrazine相关产品

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物,用于与反式环辛烯和其他应变烯烃的 TCO 连接。

Alkyne-PEG3-OH

Alkyne-PEG3-OH is a triethyleneglycol based bifunctional linker with a hydroxyl group and an alkyne fragment.

Alkyne-PEG3-OH 是一种基于三甘醇的双功能接头,具有羟基和炔烃片段。

General properties

Appearance: purple oil 紫油
Molecular weight: 334.37
Molecular formula: C16H22N4O4
IUPAC name: 2-(2-{2-[2-(6-Phenyl-1,2,4,5-tetraazin-3-yl)ethoxy]ethoxy}ethoxy)ethanol
Solubility: good in most organic solvents (excluding hydrocarbons)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications