Sulfo-Cy7.5 dicarboxylic acid

Sulfo-Cy7.5 dicarboxylic acid,Sulfo-Cy7.5 二羧酸是一种具有两个羧酸基团的双功能近红外荧光染料。

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  • Sulfo-Cyanine7.5 dicarboxylic acid

Sulfo-Cyanine7.5 dicarboxylic acid

标签:Carboxylic acids, Near infrared (NIR) imaging, sulfo-Cy7.5
货号 规格 价格 货期
1382-1mg 1 mg 110.00$ in stock
1382-5mg 5 mg 290.00$ in stock
1382-25mg 25 mg 690.00$ in stock
1382-50mg 50 mg 1270.00$ in stock
1382-100mg 100 mg 1990.00$ in stock
Sulfo-Cyanine7.5 dicarboxylic acid is a bifunctional near infrared fluorescent dye with two carboxylic acid groups.

The reagent is useful as a cross-linker that is NIR emitting. The carboxylic acid groups can be activated by carbodiimide chemistry.

Sulfo-Cy7.5 二羧酸是一种具有两个羧酸基团的双功能近红外荧光染料。

该试剂可用作发射 NIR 的交联剂。 羧酸基团可以通过碳二亚胺化学活化。

Sulfo-Cyanine7.5 dicarboxylic acid Sulfo-Cyanine7.5 dicarboxylic acid Sulfo-Cyanine7.5 dicarboxylic acid Sulfo-Cyanine7.5 dicarboxylic acid

Absorption and emission spectra of sulfo-Cyanine7.5 fluorophore

Sulfo-Cyanine7.5 dicarboxylic acid

Sulfo-Cy7.5 dicarboxylic acid相关产品

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.

Pico488 是一种染料,用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光,在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。

Cyanine5 carboxylic acid

Cyanine5 carboxylic acid, unactivated dye.

Cy5羧酸,未活化染料。

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 is a near infrared fluorophore similar to indocyanine green (ICG), but possessing higher fluorescence quantum yield. The dye is very hydrophilic and water soluble. The reagent is very useful for the labeling of biomolecules for in vivo imaging. This is an alkyne for copper catalyzed Click chemistry.

Sulfo-Cy7.5 是一种类似于吲哚菁绿 (ICG) 的近红外荧光团,但具有更高的荧光量子产率。 该染料是非常亲水和水溶性的。 该试剂对于标记用于体内成像的生物分子非常有用。 这是一种用于铜催化点击化学的炔烃。

General properties

Appearance: dark green solid
Molecular weight: 1183.51
Molecular formula: C50H53N2K3O16S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

Sulfo-Cyanine7 tetrazine

Sulfo-Cyanine7 tetrazine,Sulfo-Cy7 是一种近红外水溶性荧光团。 该衍生物含有甲基四嗪基团,可在称为 TCO 连接的反应中与环烯烃进行快速、高效且无金属的共轭。

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  • Sulfo-Cyanine7 tetrazine

Sulfo-Cyanine7 tetrazine

标签:sulfo-Cyanine7,sulfo-Cy7, Near infrared (NIR) imaging, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
153E0 1 mg 110.00$ in stock
253E0 5 mg 290.00$ in stock
453E0 25 mg 690.00$ in stock
553E0 50 mg 1270.00$ in stock
653E0 100 mg 1990.00$ in stock

Sulfo-Cyanine7 is a near infrared, water soluble fluorophore. This derivative contains methyltetrazine group for the fast, efficient, and metal free conjugation with cycloalkenes in a reaction called TCO ligation.

Sulfo-Cy7 是一种近红外水溶性荧光团。 该衍生物含有甲基四嗪基团,可在称为 TCO 连接的反应中与环烯烃进行快速、高效且无金属的共轭。

Sulfo-Cyanine7 absorption and emission spectra

Sulfo-Cyanine7 tetrazine

Sulfo-Cyanine7 tetrazine相关产品

Cyanine3 tetrazine

Tetrazine derivative of the fluorophore Cyanine3. Tetrazines react extremely quickly with strained alkenes (such as trans-cyclooctenes, cyclopropenes), and some strained alkynes.

荧光团 Cy3 的四嗪衍生物。 四嗪与应变烯烃(如反式环辛烯、环丙烯)和一些应变炔烃反应极快。

AF430 tetrazine

Tetrazine derivative of AF430 fluorescent dye suitable for in vitro cell labeling.

AF430 荧光染料的四嗪衍生物,适用于体外细胞标记。

Sulfo-Cyanine5.5 NHS ester

Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.

NHS 酯形式的水溶性磺化远红色磺基-Cyanine5.5 染料。

General properties

Appearance: dark green solid  深绿色固体
Mass spec M+ increment: 863.3
Molecular weight: 930.19
Molecular formula: C47H52N7KO7S2
Solubility: good in DMF, DMSO, water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

Sulfo-Cyanine7 amine

Sulfo-Cyanine7 amine,Cyanine7 NIR 染料的磺化、水溶性氨基衍生物。这种 NIR 染料胺可用于通过与亲电子基团的反应以及涉及氨基转移的酶促反应衍生各种靶标。

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  • Sulfo-Cyanine7 amine

Sulfo-Cyanine7 amine

标签:sulfo-Cyanine7, Amines, Near infrared (NIR) imaging
货号 规格 价格 货期
153C0 1 mg 110.00$ in stock
253C0 5 mg 290.00$ in stock
453C0 25 mg 690.00$ in stock
553C0 50 mg 1270.00$ in stock
653C0 100 mg 1990.00$ in stock

Sulfonated, water-soluble, amino derivative of Cyanine7 NIR dye.

This NIR dye amine can be used for the derivatization of various targets by the reaction with electrophilic groups, and also by enzymatical reactions involving transamination.

Cyanine7 NIR 染料的磺化、水溶性氨基衍生物。

这种 NIR 染料胺可用于通过与亲电子基团的反应以及涉及氨基转移的酶促反应衍生各种靶标。

Sulfo-Cyanine7 absorbance and emission spectra

Sulfo-Cyanine7 amine

Sulfo-Cyanine7 amine相关产品

Cyanine5 carboxylic acid

Cyanine5 carboxylic acid, unactivated dye.

Cy5羧酸,未活化染料。

ROX DBCO, 5-isomer

ROX (rhodamine X) is a bright rhodamine dye. This is a DBCO (dibenzocyclooctyne) derivative that has high reactivity against azides.

ROX(罗丹明 X)是一种明亮的罗丹明染料。 这是一种对叠氮化物具有高反应性的 DBCO(二苯并环辛炔)衍生物。

Amino-11-dUTP

Amino-11-dUTP is a triphosphate for the modification of DNA.

Amino-11-dUTP 是一种用于修饰 DNA 的三磷酸盐。

General properties

Appearance: dark green powder 深绿色粉末
Molecular weight: 807.07
CAS number: 2236573-39-8
Molecular formula: C43H58N4O7S2
Solubility: very poorly soluble in water (0.50 mM = 40 mg/L), good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

相关文献:

  1. Kim, H.; Han, J.; Park, J.-H. Cyclodextrin polymer improves atherosclerosis therapy and reduces ototoxicity. Journal of Controlled Release, 2020, 319, 77–86. doi: 10.1016/j.jconrel.2019.12.021
  2. Rippe, M.; Stefanello, T.F.; Kaplum, V.; Britta, E.A.; Garcia, F.P.; Poirot, R.; Companhoni, M.V.P.; Nakamura, C.V.; Szarpak-Jankowska, A.; Auzély-Velty, R. Heparosan as a potential alternative to hyaluronic acid for the design of biopolymer-based nanovectors for anticancer therapy. Biomaterials Science, 2019, 7, 2850–2860. doi: 10.1039/c9bm00443b
  3. Guo, X.; Zou, C.-L.; Jung, H.; Gong, Z.; Bruch, A.; Jiang, L.; Tang, H.X. Efficient Generation of a Near-visible Frequency Comb via Cherenkov-like Radiation from a Kerr Microcomb. Physical Review Applied, 2018, 10(1), 014012. doi: 10.1103/PhysRevApplied.10.014012
  4. Tabe, H.; Sukenobe, K.; Kondo, T.; Sakurai, A.; Maruo, M.; Shimauchi, A.; Hirano, M.; Uno, S.-N.; Kamiya, M.; Urano, Y.; Matsushita, M.; Fujiyoshi, S. Cryogenic Fluorescence Localization Microscopy of Spectrally Selected Individual FRET Pairs in a Water Matrix. The Journal of Physical Chemistry B, 2018, 122(27), 6906–6911. doi: 10.1021/acs.jpcb.8b03977
Cy® is a trademark of GE Healthcare.

Cyanine7.5 amine

Cyanine7.5 amine,Cy7.5 是一种 NIR 荧光染料。 该试剂含有游离氨基,可与活化的羧酸衍生物偶联使用。

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  • Cyanine7.5 amine

Cyanine7.5 amine

标签:Cyanine7.5,Cy7.5, Amines, Near infrared (NIR) imaging
货号 规格 价格 货期
160C0 1 mg 110.00$ in stock
260C0 5 mg 210.00$ in stock
360C0 10 mg 310.00$ in stock
460C0 25 mg 410.00$ in stock
560C0 50 mg 695.00$ in stock
660C0 100 mg 1190.00$ in stock
Cyanine7.5 is a NIR fluorescent dye. This reagent contains free amino group which can be used coupled with activated carboxylic acid derivatives.
Cy7.5 是一种 NIR 荧光染料。 该试剂含有游离氨基,可与活化的羧酸衍生物偶联使用。

Cy7.5 absorbance and emission spectra

Cyanine7.5 amine

Cyanine7.5 amine相关产品

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cy5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能,用于将环辛炔连接到各种分子上。

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

用于氨基生物分子标记的水溶性磺基-Cyanine3 SE 活化酯。

General properties

Appearance: dark green powder 深绿色粉末
Molecular weight: 819.99
CAS number: 2104005-17-4 (hydrichloride), 2104005-16-3 (chloride), 2104005-15-2
Molecular formula: C51H64Cl2N4O
Solubility: good in DMSO, DMF, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献:

  1. Yang, X.; Wang, Z.; Huang, H.; Ling, S.; Zhang, R.; Zhang, Y.; Chen, G.; Li, C.; Wang, Q. A Targeted Activatable NIR-IIb Nanoprobe for Highly Sensitive Detection of Ischemic Stroke in a Photothrombotic Stroke Model. Advanced Healthcare Materials, 2021, 10(5), 2001544. doi: 10.1002/adhm.202001544
  2. Bhattacharya, D.S.; Svechkarev, D.A.; Bapat, A.; Patil, P.; Hollingsworth, M.A.; Mohs, A.M. Sulfation modulates the targeting properties of hyaluronic acid to P-selectin and CD44. ACS Biomaterials Science & Engineering, 2020, 6(6), 3585–3598. doi: 10.1021/acsbiomaterials.0c00115
  3. Qi, B.; Crawford, A.J.; Wojtynek, N.E.; Talmon, G.A.; Hollingsworth, M.A.; Ly, Q.P.; Mohs, A.M. Tuned near infrared fluorescent hyaluronic acid conjugates for delivery to pancreatic cancer for intraoperative imaging. Theranostics, 2020, 10(8), 3413–3429. doi: 10.7150/thno.40688
  4. Retout, M.; Brunetti, E.; Valkenier, H.; Bruylants, G. Limits of thiol chemistry revealed by quantitative analysis of mixed layers of thiolated-PEG ligands grafted onto gold nanoparticles. Journal of Colloid and Interface Science, 2019, 557, 807–815. doi: 10.1016/j.jcis.2019.09.047
Cy® is a trademark of GE Healthcare.

Cyanine7 amine

Cyanine7 amine,具有游离胺基的近红外染料,用于与活化酯和其他反应性分子结合。Cyanine7 是一种近红外染料,是 Cy7® 的类似物,特别适用于活体生物成像和要求低背景的应用。

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  • Cyanine7 amine

Cyanine7 amine

标签:Cyanine7, Cy7, Amines, Near infrared (NIR) imaging
货号 规格 价格 货期
150C0 1 mg 110.00$ in stock
250C0 5 mg 210.00$ in stock
450C0 25 mg 410.00$ in stock
550C0 50 mg 695.00$ in stock
650C0 100 mg 1190.00$ in stock

Near infrared dye with free amine group for the conjugation with activated esters and other reactive molecules.

Cyanine7 is a near infrared dye, an analog of Cy7® which is especially suitable for live organism imaging, and demanding low-background applications.

具有游离胺基的近红外染料,用于与活化酯和其他反应性分子结合。

Cyanine7 是一种近红外染料,是 Cy7® 的类似物,特别适用于活体生物成像和要求低背景的应用。

Cy7 absorbance and emission spectra

Cyanine7 amine

Cyanine7 amine相关产品

Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Cy5 酰肼是醛和酮的活性染料。 它可用于糖部分高碘酸氧化后的糖蛋白的标记。

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AF488 azide

AF488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.

AF488 azide 是一种在绿色光谱范围内发射的荧光团。 它在铜催化的环加成反应中与炔烃反应。

Cyanine7 carboxylic acid

Non-reactive, near-infrared fluorescent dye.

非反应性近红外荧光染料。

General properties

Appearance: green powder 绿色粉末
Molecular weight: 719.87
CAS number: 1650635-41-8, 1650559-73-1 [Cl-]
Molecular formula: C43H60Cl2N4O
Solubility: soluble in water (72 mM = 51 g/L), well soluble in DMSO, DMF, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献:

  1. Ford, C.A.; Spoonmore, T.J.; Gupta, M.K.; Duvall, C.L.; Guelcher, S.A.; Cassat, J.E. Diflunisal-loaded poly(propylene sulfide) nanoparticles decrease S. aureus-mediated bone destruction during osteomyelitis. Journal of Orthopaedic Research, 2021, 39(2), 426–437. doi: 10.1002/jor.24948
  2. Shao, Z.; Flynn, R.A.; Crowe, J.L.; Zhu, Y.; Liang, J.; Jiang, W.; Aryan, F.; Aoude, P.; Bertozzi, C.R.; Estes, V.M.; Lee, B.J.; Bhagat, G.; Zha, S.; Calo, E. DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. Nature, 2020, 579, 291–296. doi: 10.1038/s41586-020-2041-2
  3. de Oliveira, J.K.; Ueda-Nakamura, T.; Corrêa, A.G.; Petrilli, R.; Lopez, R.F.V.; Nakamura, C.V.; Auzely-Velty, R. Liposome-based nanocarrier loaded with a new quinoxaline derivative for the treatment of cutaneous leishmaniasis. Materials Science and Engineering: C, 2020, 110, 110720. doi: 10.1016/j.msec.2020.110720
  4. Pola, R.; Böhmová, E.; Filipová, M.; Pechar, M.; Pankrác, J.; Větvička, D.; Olejár, T.; Kabešová, M.; Poučková, P.; Šefc, L.; Zábrodský, M.; Janoušková, O.; Bouček, J.; Etrych, T. Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors. Pharmaceutics, 2020, 12, 31. doi: 10.3390/pharmaceutics12010031
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine7.5 carboxylic acid

Sulfo-Cyanine7.5 carboxylic acid,Sulfo-Cyanine7.5 是一种水溶性的近红外荧光染料。 该染料的结构与吲哚菁绿 (ICG) 相似,但它包含一个刚性三甲炔连接剂,可增加其荧光量子产率。

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  • Sulfo-Cyanine7.5 carboxylic acid

Sulfo-Cyanine7.5 carboxylic acid

标签:Carboxylic acids, Near infrared (NIR) imaging, sulfo-Cyanine7.5, sulfo-Cy7.5,Cy7.5
货号 规格 价格 货期
16390 1 mg 110.00$ in stock
26390 5 mg 290.00$ in stock
46390 25 mg 690.00$ in stock
56390 50 mg 1270.00$ in stock
66390 100 mg 1990.00$ in stock

Sulfo-Cyanine7.5 is a water soluble, near infrared fluorescent dye. The structure of the dye is similar to indocyanine green (ICG), but it contains a rigid trimethine linker increasing its fluorescence quantum yield.

This fluorophore is useful for near infrared imaging. Sulfo-Cyanine7.5 carboxylic acid contains a free carboxy group.

Sulfo-Cyanine7.5 是一种水溶性的近红外荧光染料。 该染料的结构与吲哚菁绿 (ICG) 相似,但它包含一个刚性三甲炔连接剂,可增加其荧光量子产率。

这种荧光团可用于近红外成像。 Sulfo-Cyanine7.5 羧酸含有一个游离的羧基。

Absorption and emission spectra of sulfo-Cyanine7.5

Sulfo-Cyanine7.5 carboxylic acid

Sulfo-Cyanine7.5 carboxylic acid相关产品

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cyanine5 活化酯,用于标记蛋白质、肽和其他分子。

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.

Pico488 是一种染料,用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光,在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。

Cyanine7.5 carboxylic acid

Cyanine7.5 – unactivated NIR cyanine dye carboxylic acid.

Cyanine7.5 – 未活化的近红外花青染料羧酸。

General properties

Appearance: dark green solid 深绿色固体
Molecular weight: 1083.41
Molecular formula: C45H45K3N2O14S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

相关文献:

  1. So, I.-S.; Kang, J.H.; Hong, J.W.; Sung, S.; Hasan, A.F.; Sa, K.H.; Han, S.W.; Kim, I.S.; Kang, Y.M. A novel apoptosis probe, cyclic ApoPep-1, for in vivo imaging with multimodal applications in chronic inflammatory arthritis. Apoptosis, 2021, 26(3–4), 209–218. doi: 10.1007/s10495-021-01659-z
  2. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  3. Shi, F.; Li, M.; Wu, S.; Yang, F.; Di, W.; Pan, M.; Zhao, F.; Luo, S.; Gu, N.; Dou, J. Enhancing the Anti-Multiple Myeloma Efficiency in a Cancer Stem Cell Xenograft Model by Conjugating the ABCG2 Antibody with Microbubbles for a Targeted Delivery of Ultrasound Mediated Epirubicin. Biochemical Pharmacology, 2017, 132, 18–28. doi: 10.1016/j.bcp.2017.02.014
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine7 carboxylic acid

Sulfo-Cyanine7 carboxylic acid,Sulfo-Cyanine7 羧酸是非反应性水溶性近红外染料。

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  • Sulfo-Cyanine7 carboxylic acid

Sulfo-Cyanine7 carboxylic acid

标签:sulfo-Cyanine7, sulfo-Cy7, Carboxylic acids, Near infrared (NIR) imaging
货号 规格 价格 货期
15390 1 mg 110.00$ in stock
25390 5 mg 290.00$ in stock
45390 25 mg 690.00$ in stock
55390 50 mg 1270.00$ in stock
65390 100 mg 1990.00$ in stock

Sulfo-Cyanine7 carboxylic acid is non-reactive water soluble near infrared dye.

The reagent is useful as a fluorescent marker in NIR range when attachment to other molecules is not desired. It has high hydrophilicity and aqueous solubility, improved quantum yield in NIR range, and very high molar extinction coefficient.

This reagent contains free carboxylic acid function. Pre-activated activated ester – sulfo-Cyanine7 NHS ester is also available.

Sulfo-Cyanine7 羧酸是非反应性水溶性近红外染料。

当不需要与其他分子结合时,该试剂可用作 NIR 范围内的荧光标记。 它具有高亲水性和水溶性,在近红外范围内提高了量子产率,并且具有非常高的摩尔消光系数。

该试剂含有游离羧酸功能。 也可提供预活化的活化酯 – 磺基花青7 NHS 酯。

Sulfo-Cyanine7 absorbance and emission spectra

Sulfo-Cyanine7 carboxylic acid

Sulfo-Cyanine7 carboxylic acid相关产品

Sulfo-Cyanine7.5 azide

Sulfo-Cyanine7.5 is a very hydrophilic and water soluble dye for the near infrared region. The absorption and emission spectra of the dye are similar to indocyanine green (ICG), but sulfo-Cyanine7.5 has a much higher fluorescence quantum yield. The dye is a great choice for near infrared in vivo imaging. This is an azide for Click chemistry.

Sulfo-Cyanine7.5 是一种用于近红外区域的亲水性和水溶性染料。 该染料的吸收和发射光谱与吲哚菁绿 (ICG) 相似,但磺基-Cyanine7.5 具有更高的荧光量子产率。 该染料是近红外体内成像的绝佳选择。 这是点击化学的叠氮化物。

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.

Cy5.5 未活化的游离酸性花青染料。

Sulfo-Cyanine7 azide

Water-soluble NIR fluorescent dye azide for Click chemistry

用于点击化学的水溶性 NIR 荧光染料叠氮化物

General properties

Appearance: dark green powder 深绿色粉末
Molecular weight: 746.97
CAS number: 2104632-29-1 (inner salt); 2104632-30-4 (sodium salt)
Molecular formula: C37H43N2KO8S2
Solubility: Soluble in water, DMF, DMSO (0.10 M = 76 g/L). Practically insoluble in non-polar organic solvents.
Quality control: NMR 1H, HPLC (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

相关文献:

  1. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  2. Pfister, J.; Summer, D.; Petrik, M.; Khoylou, M.; Lichius, A.; Kaeopookum, P.; Kochinke, L.; Orasch, T.; Haas, H.; Decristoforo, C. Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores. Biomolecules, 2020, 10, 168. doi: 10.3390/biom10020168
  3. Luthman, A.S. Wide-Field fHSI with a Linescan SRDA. In: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging (Springer Thesis), 2018, 51–85. doi: 10.1007/978-3-319-98255-7_3
  4. Luthman, A.S.; Dumitru, S.; Quiros-Gonzalez, I.; Joseph, J.; Bohndiek, S.E. Fluorescence hyperspectral imaging (fHSI) using a spectrally resolved detector array. Journal of Biophotonics, 2017, 10(6–7), 840–853. doi: 10.1002/jbio.201600304
Cy® is a trademark of GE Healthcare.

Cyanine7.5 carboxylic acid

Cyanine7.5 carboxylic acid,对于偶联和标记反应,还可以考虑使用预活化的 Cyanine7.5 NHS 酯。Cyanine7.5,Cy7.5, Carboxylic acids, Near infrared (NIR) imaging

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  • Cyanine7.5 carboxylic acid

Cyanine7.5 carboxylic acid

标签:Cyanine7.5,Cy7.5, Carboxylic acids, Near infrared (NIR) imaging
货号 规格 价格 货期
16090 1 mg 110.00$ in stock
26090 5 mg 210.00$ in stock
46090 25 mg 410.00$ in stock
56090 50 mg 695.00$ in stock
66090 100 mg 1190.00$ in stock

Free unactivated Cyanine7.5 NIR dye carboxylic acid.

For coupling and labeling reactions also consider using pre-activated Cyanine7.5 NHS ester.

游离未活化的 Cyanine7.5 NIR 染料羧酸。

对于偶联和标记反应,还可以考虑使用预活化的 Cyanine7.5 NHS 酯。

Cy7.5 absorbance and emission spectra

Cyanine7.5 carboxylic acid

Cyanine7.5 carboxylic acid相关产品

Sulfo-Cyanine5 azide

Water soluble sulfo-Cyanine5 fluorescent dye azide for Click Chemistry.

用于 Click Chemistry 的水溶性磺基-Cy5 荧光染料叠氮化物。

Sulfo-Cyanine5 carboxylic acid

Water-soluble Cyanine5 carboxylic acid, non-activated fluorescent dye.

水溶性Cyanine5羧酸,非活化荧光染料。

Sulfo-Cyanine7.5 carboxylic acid

Water soluble hydrophilic near infrared fluorescent dye. Carboxylic acid form. Highly hydrophilic due to the presence of four sulfo groups.

水溶性亲水性近红外荧光染料。 羧酸形式。 由于存在四个磺基,因此具有高度亲水性。

General properties

Appearance: green powder 绿色粉末
Molecular weight: 685.34
CAS number: 1803099-44-6
Molecular formula: C45H49ClN2O2
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献:

  1. Nie, T.; He, Z.; Zhu, J.; Chen, K.; Howard, G.P.; Pacheco-Torres, J.; Minn, I.; Zhao, P.; Bhujwalla, Z.M.; Mao, H.-Q.; Liu, L.; Chen, Y. Non-invasive delivery of levodopa-loaded nanoparticles to the brain via lymphatic vasculature to enhance treatment of Parkinson’s disease. Nano Research, 2021, 14(8), 2749–2761. doi: 10.1007/s12274-020-3280-0
  2. Amar-Lewis, E.; Buaron, N.; Chintakunta, R.; Benafsha, C.; Goldbart, R.; Traitel, T.; Prasad, M.; Elkabets, M.; Kost, J. Quaternized Starch-Based Composite Nanoparticles for siRNA Delivery to Tumors. ACS Applied Nano Materials, 2021, 4(2), 2218–2229. doi: 10.1021/acsanm.1c00032
  3. DuRoss, A.N.; Landry, M.R.; Thomas, C.R.; Neufeld, M.J.; Sun, C. Fucoidan-coated nanoparticles target radiation-induced P-selectin to enhance chemoradiotherapy in murine colorectal cancer. Cancer Letters, 2021, 500, 208–219. doi: 10.1016/j.canlet.2020.11.021
  4. Landry, M.R.; DuRoss, A.N.; Neufeld, M.J.; Hahn, L.; Sahay, G.; Luxenhofer, R.; Sun, C. Low Dose Novel PARP-PI3K Inhibition via Nanoformulation Improves Colorectal Cancer Immuno-Radiotherapy. Materials Today Bio, 2020, 8, 100082. doi: 10.1016/j.mtbio.2020.100082
Cy® is a trademark of GE Healthcare.

Cyanine7 carboxylic acid

Cyanine7 carboxylic acid,游离未活化的Cy7染料羧酸。 近红外荧光染料。对于偶联和标记反应,还可以考虑使用预活化的 Cy7 NHS 酯或水溶性磺基-Cyanine7 NHS 酯。

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  • Cyanine7 carboxylic acid

Cyanine7 carboxylic acid

标签:Cyanine7,Cy7, Carboxylic acids, Near infrared (NIR) imaging
货号 规格 价格 货期
15090 1 mg 110.00$ in stock
25090 5 mg 210.00$ in stock
45090 25 mg 410.00$ in stock
55090 50 mg 695.00$ in stock
65090 100 mg 1190.00$ in stock

Free unactivated Cyanine7 dye carboxylic acid. Near-infrared fluorescent dye.

For coupling and labeling reactions also consider using pre-activated Cyanine7 NHS ester, or water-soluble sulfo-Cyanine7 NHS ester.

游离未活化的Cy7染料羧酸。 近红外荧光染料。

对于偶联和标记反应,还可以考虑使用预活化的 Cy7 NHS 酯或水溶性磺基-Cyanine7 NHS 酯。

Cyanine7 absorbance and emission spectra

Cyanine7 carboxylic acid

Cyanine7 carboxylic acid相关产品

Alkyne Phosphoramidite, 5′-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.

用于合成寡核苷酸的炔亚磷酰胺,可用于点击化学。

FAM amine, 5-isomer

Amino derivative of fluorescein, pure 5-isomer. Contains a linker arm between the aliphatic amine group, and the fluorophore. Useful for the labeling via enzymatic transamination, for the reactions with electrophilic reagents, and for reductive amination.

荧光素的氨基衍生物,纯 5-异构体。 在脂肪胺基团和荧光团之间包含一个连接臂。 可用于通过酶促氨基转移进行标记、与亲电子试剂的反应以及还原胺化。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

General properties

Appearance: green powder 绿色粉末
Molecular weight: 585.22
CAS number: 1628790-40-8 (chloride), 1628897-82-4 (without anion), 2241083-63-4 (inner salt)
Molecular formula: C37H45ClN2O2
IUPAC name: 3H-​Indolium, 2-​[2-​[3-​[2-​[1-​(5-​carboxypentyl)​-​1,​3-​dihydro-​3,​3-​dimethyl-​2H-​indol-​2-​ylidene]​ethylidene]​-​1-​cyclohexen-​1-​yl]​ethenyl]​-​1,​3,​3-​trimethyl-​, chloride
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
CF260: 0.022
CF280: 0.029

相关文献:

  1. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  2. Svenskaya, Y.I.; Genina, E.A.; Parakhonskiy, B.V.; Lengert, E.; Talnikova, E.E.; Terentyuk, G.S.; Utz, S.R.; Gorin, D.A.; Tuchin, V.V.; Sukhorukov, G. A simple non-invasive approach towards efficient transdermal drug delivery based on biodegradable particulate system. ACS Applied Materials & Interfaces, 2019, 11(19), 17270–17282. doi: 10.1021/acsami.9b04305
  3. Yang, C.; Liu, D.; Renny, A.; Kuttipillai, P.S.; Lunt, R.R. Integration of near-infrared harvesting transparent luminescent solar concentrators onto arbitrary surfaces. Journal of Luminescence, 2019, 210, 239–246. doi: 10.1016/j.jlumin.2019.02.042
  4. Luthman, A.S. Wide-Field fHSI with a Linescan SRDA. In: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging (Springer Thesis), 2018, 51–85. doi: 10.1007/978-3-319-98255-7_3
Cy® is a trademark of GE Healthcare.

Cyanine7.5 hydrazide

Cyanine7.5 hydrazide,Cy7.5 近红外 (NIR) 荧光团的羰基反应性酰肼衍生物。 这种染料具有与 ICG(吲哚菁绿)相似的光谱特性,但具有更高的荧光量子产率。 因此,这种荧光团是体内成像的理想选择。

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  • Cyanine7.5 hydrazide

Cyanine7.5 hydrazide

标签:Cyanine7.5,Cy7.5, Hydrazides, Near infrared (NIR) imaging
货号 规格 价格 货期
16070 1 mg 110.00$ in stock
26070 5 mg 210.00$ in stock
46070 25 mg 410.00$ in stock
56070 50 mg 695.00$ in stock
66070 100 mg 1190.00$ in stock

A carbonyl-reactive hydrazide derivative of Cyanine7.5 near infrared (NIR) fluorophore. This dye has similar spectral properties with ICG (indocyanine green), but has a higher quantum yield of fluorescence. Hence, this fluorophore is ideal for in vivo imaging.

This is a carbonyl-reactive dye which is particularly useful for the labeling of antibodies after periodate oxidation. It also labels other carbonyl compounds (aldehydes and ketones), for example, many saccharides.

Cy7.5 近红外 (NIR) 荧光团的羰基反应性酰肼衍生物。 这种染料具有与 ICG(吲哚菁绿)相似的光谱特性,但具有更高的荧光量子产率。 因此,这种荧光团是体内成像的理想选择。

这是一种羰基反应性染料,特别适用于高碘酸氧化后的抗体标记。 它还标记其他羰基化合物(醛和酮),例如许多糖类。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 hydrazide

Cyanine7.5 hydrazide相关产品

Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Cy5 hydrazide是醛和酮的活性染料。 它可用于糖部分高碘酸氧化后的糖蛋白的标记。

Cyanine5.5 DBCO

Cyanine5.5 is a far-red / NIR emitting dye that is useful for bioimaging studies. Cyanine5.5 DBCO is a derivative of the dye with a cycloalkyne moiety for Copper free Click chemistry.

Cy5.5 是一种远红/近红外发射染料,可用于生物成像研究。 Cy5.5 DBCO 是具有环炔部分的染料衍生物,用于无铜点击化学。

TAMRA hydrazide, 6-isomer

6-TAMRA azide is a carbonyl reactive hydrazide derivative of tetramethylrhodamine (TAMRA) fluorophore.

6-TAMRA azide 是四甲基罗丹明 (TAMRA) 荧光团的羰基反应性酰肼衍生物。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 644.4
Molecular weight: 735.82
Molecular formula: C45H52Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献:

  1. Liu, S.; Dozois, M.D.; Chang, C.N.; Ahmad, A.; Ng, D.L.T.; Hileeto, D.; Liang, H.; Reyad, M.-M.; Boyd, S.; Jones, L.W.; Gu, F.X. Prolonged Ocular Retention of Mucoadhesive Nanoparticle Eye Drop Formulation Enables Treatment of Eye Diseases Using Significantly Reduced Dosage. Molecular Pharmaceutics, 2016, 13(9), 2897–2905. doi: 10.1021/acs.molpharmaceut.6b00445
Cy® is a trademark of GE Healthcare.

Cyanine7 hydrazide

Cyanine7 hydrazide,Cy7 的酰肼衍生物,一种 NIR 荧光染料,是 Cy7® 的类似物。这种七次甲基荧光团包含一个六元环,使聚次甲基链刚性化,与母体结构相比,量子产率提高了 20%。

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  • Cyanine7 hydrazide

Cyanine7 hydrazide

标签:Cyanine7,Cy7, Hydrazides, Near infrared (NIR) imaging
货号 规格 价格 货期
15070 1 mg 110.00$ in stock
25070 5 mg 210.00$ in stock
45070 25 mg 410.00$ in stock
55070 50 mg 695.00$ in stock
65070 100 mg 1190.00$ in stock

Hydrazide derivative of Cyanine7, a NIR fluorescent dye, an analog of Cy7®.

This variety of heptamethine fluorophore contains a six-membered ring rigidizing the polymethine chain which allows to increase quantum yield by 20% compared to parent structure.

Hydrazide reacts quickly and smoothly with aldehydes and ketones yielding stable hydrazone products. This reaction is also good for the labeling of glycoproteins after periodate oxidation.

Cy7 的酰肼衍生物,一种 NIR 荧光染料,是 Cy7® 的类似物。

这种七次甲基荧光团包含一个六元环,使聚次甲基链刚性化,与母体结构相比,量子产率提高了 20%。

酰肼与醛类和酮类反应迅速而平稳,产生稳定的腙产物。 该反应也有利于高碘酸氧化后糖蛋白的标记。

Cyanine7 absorbance and emission spectra

Cyanine7 hydrazide

Cyanine7 hydrazide相关产品

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cy3羧酸。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

Cyanine5.5 maleimide

Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.

Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 544.8
Molecular weight: 635.70
CAS number: 2183440-61-9 (without anion)
Molecular formula: C37H48Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献:

  1. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
Cy® is a trademark of GE Healthcare.

sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 maleimide,sulfo-Cyanine7.5 是一种近红外荧光团,吸收和发射范围约为 800 nm。 其光谱特性允许有效利用组织 NIR 透明度窗口。 荧光团有不同的反应形式,这是一种马来酰亚胺,用于标记蛋白质和肽的 SH 基团。 磺化剂是高度亲水的。

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  • sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 maleimide

标签:Maleimides, Near infrared (NIR) imaging, sulfo-Cyanine7.5, Cy7.5
货号 规格 价格 货期
16380 1 mg 110.00$ in stock
26380 5 mg 290.00$ in stock
46380 25 mg 690.00$ in stock
56380 50 mg 1270.00$ in stock
66380 100 mg 1990.00$ in stock

sulfo-Cyanine7.5 is a near infrared fluorophore with absorption and emission ranges around 800 nm. Its spectral properties allow for the efficient leveraging of tissue NIR transparency window. The fluorophore is available as different reactive forms, this one is maleimide for the labeling of SH groups of proteins and peptides. The sulfo- version is highly hydrophilic.

Such labeled biomolecules are useful in biodistribution studies and visualization in intact organisms.

sulfo-Cyanine7.5 是一种近红外荧光团,吸收和发射范围约为 800 nm。 其光谱特性允许有效利用组织 NIR 透明度窗口。 荧光团有不同的反应形式,这是一种马来酰亚胺,用于标记蛋白质和肽的 SH 基团。 磺化剂是高度亲水的。

这种标记的生物分子可用于生物分布研究和完整生物体的可视化。

Absorption and emission spectra of sulfo-Cyanine7.5

sulfo-Cyanine7.5 maleimide

sulfo-Cyanine7.5 maleimide相关产品

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

TAMRA maleimide, 6-isomer

TAMRA is a well known xanthene dye of rhodamine series. This is a thiol reactive maleimide for the labeling of SH groups in proteins and peptides. Pure 6-isomer.

TAMRA 是众所周知的罗丹明系列呫吨染料。 这是一种硫醇反应性马来酰亚胺,用于标记蛋白质和肽中的 SH 基团。 纯 6 异构体。

Sulfo-Cyanine5 amine

Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.

磺化的 Cy5 胺衍生物,用于与亲电试剂偶联和酶促转氨标记。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1090.3
Molecular weight: 1205.52
Molecular formula: C51H51N4K3O15S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 12 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

Sulfo-Cyanine7 maleimide

Sulfo-Cyanine7 maleimide,一种带有马来酰亚胺基团的活性染料,用于标记蛋白质和其他生物分子的硫醇基团,是 Cy7® 马来酰亚胺的类似物。

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  • Sulfo-Cyanine7 maleimide

Sulfo-Cyanine7 maleimide

标签:sulfo-Cyanine7, Cy7,Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
15380 1 mg 110.00$ in stock
25380 5 mg 290.00$ in stock
45380 25 mg 690.00$ in stock
55380 50 mg 1270.00$ in stock
65380 100 mg 1990.00$ in stock

A reactive dye with a maleimide group for the labeling of thiol groups of proteins and other biomolecules, an analog of Cy7® maleimide.

Sulfo-Cyanine7 is a near infrared fluorophore which is hydrophilic and contains a rigidizing ring in its heptamethine chain that improves its photophysical properties. A great dye for various applications, including NIR imaging.

一种带有马来酰亚胺基团的活性染料,用于标记蛋白质和其他生物分子的硫醇基团,是 Cy7® 马来酰亚胺的类似物。

Sulfo-Cyanine7 是一种近红外荧光团,具有亲水性,在其七甲碱链中包含一个刚性环,可改善其光物理性质。 适用于各种应用的出色染料,包括 NIR 成像。

Sulfo-Cyanine7 maleimide absorbance and emission spectra

Sulfo-Cyanine7 maleimide

Sulfo-Cyanine7 maleimide相关产品

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯,一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

Cyanine7.5 maleimide

Cyanine7.5 maleimide is a thiol reactive near infrared dye.

Cy7.5 马来酰亚胺是一种硫醇活性近红外染料。

Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.

用于与活化酯和环氧化物偶联的花青5 胺官能化染料。

General properties

Appearance: dark green powder 深绿色粉末
Mass spec M+ increment: 868.2
Molecular weight: 869.10
CAS number: 2183440-60-8 (potassium salt), 2183440-59-5 (inner salt)
Molecular formula: C43H49KN4O9S2
IUPAC name: 1-[2-(6-{2-[(E)-2-[(E)-3-{(E)-2-[1-Methyl-3,3-dimethyl-5-(oxysulfonyl)-2-indolinylidene]ethylidene}-1-cyclohexen-1-yl]ethenyl]-3,3-dimethyl-5-(oxysulfonyl)-3H-indol-1-yl}hexanoylamino)ethyl]-1H-pyrrole-2,5-dione, potassium salt
Solubility: Good in water, DMF, DMSO. Low in non-polar organic solvents.
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

相关文献:

  1. Lee, J.; Kang, Y.K.; Oh, E.; Jeong, J.; Im, S.H.; Kim, D.K.; Lee, H.; Kim, S.-G.; Jung, K.; Chung, H.J. Nano-assembly of a Chemically Tailored Cas9 Ribonucleoprotein for In Vivo Gene Editing and Cancer Immunotherapy. Chemistry of Materials, in press. doi: 10.1021/acs.chemmater.1c02844
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide,Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料,由于存在四个磺基,因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

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  • Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide

标签:Maleimides, Near infrared (NIR) imaging, sulfo-Cyanine5.5,Cy5.5
货号 规格 价格 货期
17380 1 mg 110.00$ in stock
27380 5 mg 290.00$ in stock
47380 25 mg 690.00$ in stock
57380 50 mg 1270.00$ in stock
67380 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 dye is a water soluble far red to NIR emitting dye which is very hydrophilic due to the presence of four sulfo groups. Sulfo-Cyanine5.5 derivatives exhibit high water solubility. The dye is a perfect choice for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers.

This maleimide is a thiol reactive dye that selectively labels cysteine residues. Disulfide bonds of native proteins should be reduced with an appropriate reducing agent, such as TCEP, according to our recommended protocol.

Sulfo-Cyanine5.5 染料是一种水溶性远红至近红外发射染料,由于存在四个磺基,因此非常亲水。 Sulfo-Cyanine5.5 衍生物表现出高水溶性。 该染料是标记敏感蛋白质、纳米颗粒和高度亲水性生物聚合物的完美选择。

这种马来酰亚胺是一种选择性标记半胱氨酸残基的硫醇活性染料。 根据我们推荐的方案,应使用适当的还原剂(例如 TCEP)还原天然蛋白质的二硫键。

Absorption and emission spectra of sulfo-Cyanine5.5

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 maleimide相关产品

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cy7 NHS 酯是一种水溶性、近红外、胺反应性染料。

BDP TMR maleimide

A bright, thiol reactive dye for TAMRA channel. Useful for microscopy and fluorescence polarization assays, among other applications.

用于 TAMRA 通道的明亮硫醇活性染料。 可用于显微镜和荧光偏振测定,以及其他应用。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1024.2
Molecular weight: 1139.43
CAS number: 2183440-58-4 (potassium salt); 2183440-57-3 (inner salt)
Molecular formula: C46H45K3N4O15S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 12 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

相关文献:

  1. Ieong, K.-W.; Indrisiunaite, G.; Prabhakar, A.; Puglisi, J.D.; Ehrenberg, M. N6-Methyladenosines in mRNAs reduce the accuracy of codon reading by transfer RNAs and peptide release factors. Nucleic Acids Research, 2021, 49(5), 2684–2699. doi: 10.1093/nar/gkab033
  2. Chen, Q.; Gao, M.; Li, Z.; Xiao, Y.; Bai, X.; Boakye-Yiadom, K.O.; Xu, X.; Zhang, X.-Q. Biodegradable nanoparticles decorated with different carbohydrates for efficient macrophage-targeted gene therapy. Journal of Controlled Release, 2020, 323, 179–190. doi: 10.1016/j.jconrel.2020.03.044
  3. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0

Cyanine7.5 maleimide

Cyanine7.5 maleimide,硫醇反应性近红外染料 Cy7.5 用于标记蛋白质 SH 基团,Cy7.5® 马来酰亚胺的类似物。

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Cyanine7.5 maleimide

标签:Cyanine7.5, Cy7.5,Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
16080 1 mg 110.00$ in stock
26080 5 mg 210.00$ in stock
46080 25 mg 410.00$ 5 days
56080 50 mg 695.00$ in stock
66080 100 mg 1190.00$ in stock

Thiol-reactive, near infrared dye Cyanine7.5 for the labeling of protein SH groups, an analog of Cy7.5® maleimide.

Most proteins contain sulfhydryl groups which can be selectively labeled with maleimides. With this reagent, these proteins can be converted to near infrared (NIR) fluorescent conjugates. After it, the conjugates can be used in non-invasive live organism imaging to study distribution of the protein in tissues and organs.

硫醇反应性近红外染料 Cy7.5 用于标记蛋白质 SH 基团,Cy7.5® 马来酰亚胺的类似物。

大多数蛋白质含有巯基,可以选择性地用马来酰亚胺标记。 使用该试剂,这些蛋白质可以转化为近红外 (NIR) 荧光结合物。 之后,缀合物可用于非侵入性活体生物成像,以研究蛋白质在组织和器官中的分布。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 maleimide

Cyanine7.5 maleimide相关产品

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.

BDP 581/591 是一种硼二吡咯亚甲基荧光团,可用于荧光偏振测定、显微镜检查和两个光子实验。 该炔烃是铜催化点击化学的衍生物。

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester is a water soluble, near infrared, amine-reactive dye.

Sulfo-Cyanine7 NHS 酯是一种水溶性、近红外、胺反应性染料。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

General properties

Appearance: green powder  绿色粉末
Molecular weight: 807.46
Molecular formula: C51H55ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献:

  1. Men, Y.; Peng, S.; Yang, P.; Jiang, Q.; Zhang, Y.; Shen, B.; Dong, P.; Pang, Z.; Yang, W. Biodegradable Zwitterionic Nanogels with Long Circulation for Antitumor Drug Delivery. ACS Applied Materials & Interfaces, 2018, 10(28), 23509–23521. doi: 10.1021/acsami.8b03943
Cy® is a trademark of GE Healthcare.

Cyanine7 maleimide

Cyanine7 maleimide,近红外、巯基反应性 Cy7 染料,Cy7® 马来酰亚胺的类似物。该试剂允许将近红外 Cyanine7 染料连接到具有游离巯基的蛋白质上。 由此获得的标记蛋白质用于近红外生物成像应用。 NIR 成像系统可用于可视化标记蛋白质在组织中的分布,甚至在活生物体中。

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  • Cyanine7 maleimide

Cyanine7 maleimide

标签:Cyanine7,Cy7, Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
15080 1 mg 110.00$ in stock
25080 5 mg 210.00$ in stock
45080 25 mg 410.00$ in stock
55080 50 mg 695.00$ in stock
65080 100 mg 1190.00$ in stock

Near-infrared, sulfhydryl reactive Cyanine7 dye, an analog of Cy7® maleimide.

This reagent allows to attach near infrared Cyanine7 dye to proteins with free sulfhydryl groups. Labeled proteins thus obtained are used in NIR bioimaging applications. NIR imaging systems can be used to visualize distribution of labeled proteins in tissues even in live organism.

近红外、巯基反应性 Cy7 染料,Cy7® 马来酰亚胺的类似物。

该试剂允许将近红外 Cyanine7 染料连接到具有游离巯基的蛋白质上。 由此获得的标记蛋白质用于近红外生物成像应用。 NIR 成像系统可用于可视化标记蛋白质在组织中的分布,甚至在活生物体中。

Cyanine7 absorbance and emission spectra

Cyanine7 maleimide

Cyanine7 maleimide相关产品

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine7 tetrazine

Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.

用于 TCO 连接的含有四嗪基团的近红外 Cy7 染料衍生物。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯,一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

General properties

Appearance: green powder 绿色粉末
Molecular weight: 707.34
CAS number: 2120392-49-4 (without anion)
Molecular formula: C43H51ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献:

  1. Liu, Y.; Fens, M.H.A.M.; Lou, B.; van Kronenburg, N.C.H.; Maas-Bakker, R.F.M.; Kok, R.J.; Oliveira, S.; Hennink, W.E.; van Nostrum, C.F. π-π-Stacked Poly(ε-caprolactone)-b-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy. Pharmaceutics, 2020, 12(4), 338. doi: 10.3390/pharmaceutics12040338
  2. Liu, Y.; Scrivano, L.; Peterson, J.D.; Fens, M.H.A.M.; Beltrán Hernández, I.; Mesquita, B.; Sastre Torano, J.; Hennink, W.E.; van Nostrum, C.F.; Oliveira, S. EGFR targeted nanobody functionalized polymeric micelles loaded with mTHPC for selective photodynamic therapy. Molecular Pharmaceutics, 2020, 17(4), 1276–1292. doi: 10.1021/acs.molpharmaceut.9b01280
  3. Melgar-Asensio, I.; Kandela, I.; Aird, F.; Darjatmoko, S.R.; de Los Rios, C.; Sorenson, C.M.; Albert, D.M.; Sheibani, N.; Henkin, J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Investigative Ophthalmology & Visual Science, 2018, 59(10), 4071–4081. doi: 10.1167/iovs.18-24087
  4. Matsuoka, D.; Watanabe, H.; Shimizu, Y.; Kimura, H.; Yagi, Y.; Kawai, R.; Ono, M.; Saji, H. Structure–activity relationships of succinimidyl-Cys-C (O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2291–2301. doi: 10.1016/j.bmc.2018.03.015
Cy® is a trademark of GE Healthcare.

BDP 650/665 maleimide

BDP 650/665 maleimide,BDP 650/665 是一种用于 Cyanine5 (Cy5) 通道的明亮红色发射荧光团。 该染料具有较高的摩尔消光系数和良好的发射量子产率。 该染料具有中等疏水性,但可用于标记水环境中的生物分子,因此是 Cy5 的良好替代品。

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  • BDP 650/665 maleimide

BDP 650/665 maleimide

标签:Maleimides, Near infrared (NIR) imaging, BDP 650/665
货号 规格 价格 货期
18480 1 mg 110.00$ in stock
28480 5 mg 210.00$ in stock
48480 25 mg 410.00$ in stock
58480 50 mg 695.00$ in stock
68480 100 mg 1190.00$ in stock

Maleimide is a thiol reactive group. The compound can be used for the labeling of cysteine residues of proteins and peptides, among other SH-containing molecules.

BDP 650/665 是一种用于 Cyanine5 (Cy5) 通道的明亮红色发射荧光团。 该染料具有较高的摩尔消光系数和良好的发射量子产率。 该染料具有中等疏水性,但可用于标记水环境中的生物分子,因此是 Cy5 的良好替代品。

马来酰亚胺是硫醇反应基团。 该化合物可用于标记蛋白质和肽以及其他含 SH 分子的半胱氨酸残基。

Absorption and emission spectra of BDP 650/665

BDP 650/665 maleimide

BDP 650/665 maleimide相关产品

FAM maleimide, 6-isomer

Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.

荧光素 (FAM) 马来酰亚胺是一种衍生自异构纯 6-FAM 的硫醇活性染料。 荧光素是一种与各种荧光测量仪器兼容的明亮染料。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

BDP TR maleimide

BDP TR is a multi-purpose fluorophore with absorption and emission channels matching ROX dye. BDP TR is suitable for two photon, and fluorescence polarization studies.

BDP TR 是一种多用途荧光团,具有与 ROX 染料匹配的吸收和发射通道。 BDP TR 适用于两个光子和荧光偏振研究。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 555.2
Molecular weight: 555.34
Molecular formula: C29H24N5BF2O4
Solubility: good in DMF, DMSO, low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 649
ε, L⋅mol−1⋅cm−1: 94000
Emission maximum, nm: 667
Fluorescence quantum yield: 0.52
CF260: 0.04
CF280: 0.04

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 alkyne,Sulfo-Cyanine7.5 是一种近红外磺化花青染料,具有刚性化的三亚甲基链。 荧光团在结构上与已获准供人类使用的吲哚菁绿 (ICG) 染料非常相似。 然而,由于其刚性结构,染料具有改进的量子产率。

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  • Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 alkyne

标签:Alkynes, Near infrared (NIR) imaging, sulfo-Cyanine7.5,Cy7.5
货号 规格 价格 货期
A63B0 1 mg 110.00$ in stock
B63B0 5 mg 290.00$ in stock
C63B0 10 mg 470.00$ in stock
D63B0 25 mg 690.00$ in stock
E63B0 50 mg 1270.00$ in stock
F63B0 100 mg 1990.00$ in stock

Sulfo-Cyanine7.5 is a near infrared, sulfonated cyanine dye with rigidized trimethylene chain. The fluorophore is structurally very similar to indocyanine green (ICG) dye that has been approved for human use. However, the dye has an improved quantum yield because of its rigidized structure.

This is an alkyne derivative for copper catalyzed Click chemistry.

Sulfo-Cyanine7.5 是一种近红外磺化花青染料,具有刚性化的三亚甲基链。 荧光团在结构上与已获准供人类使用的吲哚菁绿 (ICG) 染料非常相似。 然而,由于其刚性结构,染料具有改进的量子产率。

这是一种用于铜催化点击化学的炔烃衍生物。

Absorption and emission spectra of sulfo-Cyanine7.5

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 alkyne相关产品

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃,5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

Sulfo-Cyanine7.5 NHS ester

A water soluble near infrared emitting dye for in vivo imaging applications. Sulfo-Cyanine7.5 is an analog of indocyanine green (ICG) possessing higher emission quantum yield, and containing a linker arm.

一种用于体内成像应用的水溶性近红外发射染料。 Sulfo-Cyanine7.5 是吲哚菁绿 (ICG) 的类似物,具有更高的发射量子产率,并包含一个连接臂。

sulfo-Cyanine7 dicarboxylic acid

Sulfo-Cyanine7 dicarboxylic acid is a bifunctional dye with two carboxyl groups.

Sulfo-Cyanine7 二羧酸是一种具有两个羧基的双功能染料。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 1005.2
Molecular weight: 1120.46
Molecular formula: C48H48N3K3O13S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

Cyanine7.5 alkyne

Cyanine7.5 alkyne,Cy7.5 的炔烃衍生物,一种近红外荧光团。 该炔烃适用于铜催化的点击化学。这种荧光团可用于体内成像,其光谱特性与 ICG(吲哚菁绿)相似,具有更高的荧光量子产率。

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  • Cyanine7.5 alkyne

Cyanine7.5 alkyne

标签:Cyanine7.5,Cy7.5, Alkynes, Near infrared (NIR) imaging
货号 规格 价格 货期
A60B0 1 mg 110.00$ in stock
B60B0 5 mg 210.00$ in stock
C60B0 10 mg 310.00$ in stock
D60B0 25 mg 410.00$ in stock
E60B0 50 mg 695.00$ in stock
F60B0 100 mg 1190.00$ in stock

Alkyne derivative of Cyanine7.5, a near infrared fluorophore. This alkyne is suitable for copper-catalyzed Click Chemistry.

This fluorophore is useful for in vivo imaging, its spectral properties are similar to ICG (indocyanine green) with somewhat higher fluorescence quantum yield.

Cyanine7.5 的炔烃衍生物,一种近红外荧光团。 该炔烃适用于铜催化的点击化学。

这种荧光团可用于体内成像,其光谱特性与 ICG(吲哚菁绿)相似,具有更高的荧光量子产率。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 alkyne

Cyanine7.5 alkyne相关产品

Biotin-PEG3-Azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Biotin azide 是一种用生物素(一种众所周知的亲和探针)进行点击化学标记的试剂。

Cyanine7.5 carboxylic acid

Cyanine7.5 – unactivated NIR cyanine dye carboxylic acid.

Cy7.5 – 未活化的近红外花青染料羧酸。

R6G alkyne, 6-isomer

R6G (rhodamine 6G) terminal alkyne for copper catalyzed Click chemistry reaction with azides. Pure 6-isomer of the dye.

R6G(罗丹明 6G)末端炔烃用于铜催化与叠氮化物的点击化学反应。 染料的纯 6-异构体。

General properties

Appearance: dark green powder 深绿色粉末
Mass spec M+ increment: 686.4
Molecular weight: 722.40
Molecular formula: C48H52ClN3O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献:

  1. Chan, P.S.; Xian, J.W.; Li, Q.; Chan, C.W.; Leung, S.S.Y.; To, K.K.W. Biodegradable Thermosensitive PLGA-PEG-PLGA Polymer for Non-irritating and Sustained Ophthalmic Drug Delivery. AAPS Journal, 2019, 21, 59. doi: 10.1208/s12248-019-0326-x
Cy® is a trademark of GE Healthcare.

Cyanine7 alkyne

Cyanine7 alkyne,Cyanine7 的炔烃衍生物,一种近红外荧光团,Cy7® 的类似物。 炔烃可以通过铜催化的点击化学与多种叠氮化物结合。该染料在水中的溶解度有限,但可以在添加 DMSO 或 DMF 的水性缓冲液中成功偶联。

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  • Cyanine7 alkyne

Cyanine7 alkyne

标签:Cyanine7, Cy7,Alkynes, Near infrared (NIR) imaging
货号 规格 价格 货期
A50B0 1 mg 110.00$ in stock
B50B0 5 mg 210.00$ in stock
C50B0 10 mg 310.00$ in stock
D50B0 25 mg 410.00$ in stock
E50B0 50 mg 695.00$ in stock
F50B0 100 mg 1190.00$ in stock

Alkyne derivative of Cyanine7, a near infrared fluorophore, analog of Cy7®. The alkyne can be conjugated to a variety of azides via copper-catalyzed Click chemistry.

The dye has limited solubility in water, but it can be successfully conjugated in aqueous buffers with the addition of DMSO or DMF.

Cyanine7 的炔烃衍生物,一种近红外荧光团,Cy7® 的类似物。 炔烃可以通过铜催化的点击化学与多种叠氮化物结合。

该染料在水中的溶解度有限,但可以在添加 DMSO 或 DMF 的水性缓冲液中成功偶联。

Cyanine7 absorbance and emission spectra

Cyanine7 alkyne

Cyanine7 alkyne相关产品

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cy5 azide 是一种用 Cy5(一种流行的荧光染料)进行 Click Chemistry 标记的试剂。

Cyanine7 maleimide

Cyanine7 maleimide is a sulfhydryl-reactive NIR dye.

Cy7 马来酰亚胺是一种巯基反应性 NIR 染料。

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 586.4
Molecular weight: 622.28
CAS number: 1998119-13-3 (chloride), 1954687-62-7
Molecular formula: C40H48ClN3O
Solubility: good in DMSO, DMF, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献:

  1. Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
  2. Hwang, D.; Nilchan, N.; Nanna, A.R.; Li, X.; Cameron, M.D.; Roush, W.R.; Park, H.; Rader, C. Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues. Cell Chemical Biology, 2019, 26(9), 1229–1239. doi: 10.1016/j.chembiol.2019.05.010
  3. Conibear, A.C.; Thewes, K.; Groysbeck, N.; Becker, C.F.W. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry, 2019, 7, 113. doi: 10.3389/fchem.2019.00113
  4. Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine7.5 azide,叠氮化物,Dye azides

Sulfo-Cyanine7.5 azide,叠氮化物,Dye azides,Sulfo-Cyanine7.5 是一种七甲炔花青染料,适用于光谱的近红外区域,具有很强的亲水性和水溶性。 荧光团类似于在体内使用历史悠久的 ICG(吲哚菁绿),甚至被批准用于人体血管造影。 然而,与 ICG 相比,磺基-Cyanine7.5 具有显着提高的荧光量子产率,这是由于用三亚甲基桥加强的崎岖多甲炔链。

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  • Sulfo-Cyanine7.5 azide

Sulfo-Cyanine7.5 azide

标签:Azides, Near infrared (NIR) imaging, sulfo-Cyanine7.5,Cy7.5,叠氮化物,Dye azides
货号 规格 价格 货期
A6330 1 mg 110.00$ in stock
B6330 5 mg 290.00$ in stock
C6330 10 mg 470.00$ in stock
D6330 25 mg 690.00$ in stock
E6330 50 mg 1270.00$ in stock
F6330 100 mg 1990.00$ in stock

Sulfo-Cyanine7.5 is a heptamethyne cyanine dye for the near infrared region of the spectrum, which is very hydrophilic, and water soluble. The fluorophore resembles ICG (indocyanine green) that has a long history of in vivo use, and is even approved for human angiography. However, compared to ICG, sulfo-Cyanine7.5 has a significantly improved fluorescence quantum yield due to the rugged polymethine chain reinforced with trimethylene bridge.

Sulfo-Cyanine7.5 is available as a number of reactive derivatives. This azide can be used for the easy labeling of various biomolecules by copper-catalyzed or copper free Click chemistry.

Sulfo-Cyanine7.5 是一种七甲炔花青染料,适用于光谱的近红外区域,具有很强的亲水性和水溶性。 荧光团类似于在体内使用历史悠久的 ICG(吲哚菁绿),甚至被批准用于人体血管造影。 然而,与 ICG 相比,磺基-Cyanine7.5 具有显着提高的荧光量子产率,这是由于用三亚甲基桥加强的崎岖多甲炔链。

Sulfo-Cyanine7.5 可作为许多反应性衍生物使用。 这种叠氮化物可用于通过铜催化或无铜点击化学轻松标记各种生物分子。

Absorption and emission spectra of sulfo-Cyanine7.5 fluorophore

Sulfo-Cyanine7.5 azide

Sulfo-Cyanine7.5 azide,叠氮化物,Dye azides

FAM azide, 6-isomer

FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.

FAM(荧光素)叠氮化物,6 异构体是 Click Chemistry 中常用的荧光染料叠氮化物。

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cyanine5.5 azide 是水溶性远红荧光花青染料的衍生物。 叠氮基可以通过铜催化或无铜点击化学进行缀合。 该试剂具有高水溶性和亲水性,推荐用于水环境中生物分子的标记。

Azide-PEG3-Azide

Triethylene glycol diazide (CAS# 59559-06-7) is a bifunctional crosslinker bearing two azide groups. Suitable for Click chemistry.

三甘醇二叠氮化物 (CAS# 59559-06-7) 是一种带有两个叠氮基的双功能交联剂。 适用于点击化学。

General properties

Appearance: dark colored solid  深色固体
Mass spec M+ increment: 1050.3
Molecular weight: 1165.51
Molecular formula: C48H51N6K3O13S4
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

Sulfo-Cyanine7 azide,Cy7 叠氮化物

Sulfo-Cyanine7 azide,Cy7 叠氮化物,一种用于 Click Chemistry 的水溶性 NIR 染料叠氮化物。 Sulfo-Cyanine7 是一种花青染料,是 Cy7® 的类似物,具有改进的光物理特性。这种染料是活体生物近红外成像研究的完美选择。

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  • Sulfo-Cyanine7 azide

Sulfo-Cyanine7 azide

标签:sulfo-Cyanine7, Cy7,Azides, Near infrared (NIR) imaging
货号 规格 价格 货期
A5330 1 mg 110.00$ in stock
B5330 5 mg 290.00$ in stock
C5330 10 mg 470.00$ in stock
D5330 25 mg 690.00$ in stock
E5330 50 mg 1270.00$ in stock
F5330 100 mg 1990.00$ in stock

A water-soluble NIR dye azide for Click Chemistry. Sulfo-Cyanine7 is a cyanine dye, an analog of Cy7® with improved photophysical properties.

This dye is a perfect choice for NIR imaging studies in live organisms.

一种用于 Click Chemistry 的水溶性 NIR 染料叠氮化物。 Sulfo-Cyanine7 是一种花青染料,是 Cy7® 的类似物,具有改进的光物理特性。

这种染料是活体生物近红外成像研究的完美选择。

Sulfo-Cyanine7 absorbance and emission spectra

Sulfo-Cyanine7 azide

Sulfo-Cyanine7 azide,Cy7 叠氮化物相关产品

Sulfo-Cyanine7 carboxylic acid

Sulfo-Cy7 carboxylic acid is a non-reactive fluorescent dye which can be used as a NIR (near infrared) marker.

Sulfo-Cy7 羧酸是一种非反应性荧光染料,可用作 NIR(近红外)标记。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

Cyanine7 hydrazide

Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.

羰基反应性 NIR 荧光团,用于标记醛、酮,包括经过高碘酸盐氧化的糖蛋白。

General properties

Appearance: dark green powder 深绿色粉末
Molecular weight: 829.08
Molecular formula: C40H49N6KO7S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04
Cy® is a trademark of GE Healthcare.

Cyanine7.5 azide,Cy7.5 叠氮化物

Cyanine7.5 azide,Cy7.5 叠氮化物,Cyanine7.5 是一种具有长波红外荧光的 NIR 染料。 该衍生物是 Click Chemistry 的叠氮化物。可用于构建含有 Cyanine7.5、近红外荧光染料和改进的 Cy7.5® 类似物的各种标记生物分子。 当用于体内成像时,这些缀合物可以利用 NIR 组织透明度。 这种荧光团也可用于其他荧光应用,尤其是需要低荧光背景的应用。

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  • Cyanine7.5 azide

Cyanine7.5 azide

标签:Cyanine7.5,Cy7.5, Azides, Near infrared (NIR) imaging
货号 规格 价格 货期
46030 1 mL, 10 mM in DMSO 410.00$ in stock
16030 100 uL, 10 mM/DMSO 110.00$ in stock
36030 500 uL, 10 mM/DMSO 210.00$ in stock
A6030 1 mg 110.00$ in stock
B6030 5 mg 210.00$ in stock
C6030 10 mg 310.00$ in stock
D6030 25 mg 410.00$ in stock
E6030 50 mg 695.00$ in stock
F6030 100 mg 1190.00$ in stock

Cyanine7.5 is a NIR dye with long-wave infrared fluorescence. This derivative is azide for Click Chemistry.

Can be used for the construction of various labeled biomolecules containing Cyanine7.5, near infrared fluorescent dye, and an improved analog of Cy7.5®. These conjugates can take advantage of NIR tissue transparency when used for in vivo imaging. This fluorophore is also useful for other fluorescent applications, especially requiring low fluorescent background.

Azide is available as DMSO solution, ready for general Click Chemistry labeling protocol, or in solid form for custom labeling applications.

Structure features rigid bridged polymethyne chain to increase quantum yield by 20%, allowing for brighter signal.

Cyanine7.5 是一种具有长波红外荧光的 NIR 染料。 该衍生物是 Click Chemistry 的叠氮化物。

可用于构建含有 Cyanine7.5、近红外荧光染料和改进的 Cy7.5® 类似物的各种标记生物分子。 当用于体内成像时,这些缀合物可以利用 NIR 组织透明度。 这种荧光团也可用于其他荧光应用,尤其是需要低荧光背景的应用。

叠氮化物以 DMSO 溶液的形式提供,可用于一般的 Click Chemistry 标记方案,或以固体形式用于定制标记应用。

结构具有刚性桥接聚甲炔链,可将量子产率提高 20%,从而获得更亮的信号。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 azide

Cyanine7.5 azide,Cy7.5 叠氮化物相关产品

BDP FL azide

BDP FL is a bright and photostable borondipyrromethene dye for fluorescein channel. This is a dye azide for Click Chemistry.

BDP FL 是一种用于荧光素通道的明亮且光稳定的硼二吡咯亚甲基染料。 这是一种用于 Click Chemistry 的染料叠氮化物。

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物,用于与反式环辛烯和其他应变烯烃的 TCO 连接。

Cyanine5 alkyne

Cyanine5 alkyne is an alkyne dye for Click Chemistry.

Cy5 炔烃是一种用于 Click Chemistry 的炔烃染料。

General properties

Appearance: green powder / solution 绿色粉末/溶液
Molecular weight: 767.44
CAS number: 1628790-36-2; 1628897-78-8 (without anion)
Molecular formula: C48H55ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献:

  1. Hellyer, S.D.; Aggarwal, S.; Chen, A.N.; Leach, K.; Lapinsky, D.J.; Gregory, K.J. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. ACS Chemical Neuroscience, 2020, 11(11), 1597–1609. doi: 10.1021/acschemneuro.0c00009
  2. Retout, M.; Brunetti, E.; Valkenier, H.; Bruylants, G. Limits of thiol chemistry revealed by quantitative analysis of mixed layers of thiolated-PEG ligands grafted onto gold nanoparticles. Journal of Colloid and Interface Science, 2019, 557, 807–815. doi: 10.1016/j.jcis.2019.09.047
  3. Pearce, H.A.; Qian, H.; Connell, T.U.; Huang, D.; Gottstein, C.; Donnelly, P.S.; Peter, K.; Gregorevic, P.; Hagemeyer, C.E. Site-specific glycation and chemo-enzymatic antibody sortagging for the retargeting of rAAV6 to inflamed endothelium. Molecular Therapy – Methods & Clinical Development, 2019, 14, 261–269. doi: 10.1016/j.omtm.2019.07.003
  4. Kong, J.-N.; Zhu, Z.; Itokazu, Y.; Wang, G.; Dinkins, M.B.; Zhong, L.; Lin, H.-P.; Elsherbini, A.; Leanhart, S.; Jiang, X.; Qin, H.; Zhi, W.; Spassieva, S.D.; Bieberich, E. Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. Journal of Lipid Research, 2018, 59(3), 488–506. doi: 10.1194/jlr.M081877
Cy® is a trademark of GE Healthcare.

Cy7 azide,Cy7 叠氮化物

Cy7 azide,Cy7 叠氮化物,Cyanine7 azide 是一种用于 Click Chemistry 标记的近红外荧光染料叠氮化物,是 Cy7® 叠氮化物的类似物。该产品可用于通过 Click Chemistry 将 Cy7 结合到各种炔基化生物分子中。 使用这种叠氮化物也可以对寡核苷酸进行合成后修饰。环己烷桥接的聚甲炔链允许量子产率增加 20%(与母体非桥接结构相比)。

  • Products
  • Reactive dyes
  • Dye azides
  • Cyanine7 azide

Cyanine7 azide

标签:Cyanine7,Cy7, Azides, Near infrared (NIR) imaging
货号 规格 价格 货期
15030 100 uL, 10 mM/DMSO 110.00$ in stock
35030 500 uL, 10 mM/DMSO 210.00$ in stock
45030 1 mL, 10 mM/DMSO 410.00$ in stock
A5030 1 mg 110.00$ in stock
B5030 5 mg 210.00$ in stock
C5030 10 mg 310.00$ in stock
D5030 25 mg 410.00$ in stock
E5030 50 mg 695.00$ in stock

Cyanine7 azide is a near-infrared fluorescent dye azide for Click Chemistry labeling, an analog of Cy7® azide.

This product can be used for the incorporation of Cyanine7 into various alkynylated biomolecules via Click Chemistry. Post-synthetic modification of oligonucleotides is also possible with this azide.

Cyclohexane-bridged polymethyne chain allows for 20% increase in quantum yield (compared to parent non-bridged structure).

Cyanine7 azide 是一种用于 Click Chemistry 标记的近红外荧光染料叠氮化物,是 Cy7® 叠氮化物的类似物。

该产品可用于通过 Click Chemistry 将 Cy7 结合到各种炔基化生物分子中。 使用这种叠氮化物也可以对寡核苷酸进行合成后修饰。

环己烷桥接的聚甲炔链允许量子产率增加 20%(与母体非桥接结构相比)。

Cyanine7 absorbance and emission spectra

Cyanine7 azide

Cy7 azide,Cy7 叠氮化物相关产品

Cyanine5 alkyne

Cyanine5 alkyne is an alkyne dye for Click Chemistry.

Cy5 炔烃是一种用于 Click Chemistry 的炔烃染料。

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

水溶性 NIR 染料胺,Cy7 染料的磺化衍生物,用于通过酶促氨基转移进行修饰。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

General properties

Appearance: green powder / solution
Molecular weight: 667.33
CAS number: 1557149-65-1 (chloride), 1557397-59-7
Molecular formula: C40H51ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献:

  1. Roberts, S.; Khera, E.; Choi, C.; Navaratna, T.; Grimm, J.; Thurber, G.M.; Reiner, T. Optoacoustic imaging of Glucagon-like Peptide 1 Receptor with a near-infrared exendin-4 analog. Journal of Nuclear Medicine, 2021, 62(6), 839–848. doi: 10.2967/jnumed.120.252262
  2. Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
  3. Meka, R.R.; Venkatesha, S.H.; Moudgil, K.D. Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. Journal of Controlled Release, 2018, 286, 279–288. doi: 10.1016/j.jconrel.2018.08.007
  4. Lyu, Z.; Kang, L.; Buuh, Z.Y.; Jiang, D.; McGuth, J.C.; Du, J.; Wissler, H.L.; Cai, W.; Wang, R.E. A Switchable Site-Specific Antibody Conjugate. ACS Chemical Biology, 2018, 13(4), 958–964. doi: 10.1021/acschembio.8b00107
Cy® is a trademark of GE Healthcare.

BDP 650/665 azide

BDP 650/665 azide,BDP 650/665 是一种明亮的红色发光硼二吡咯亚甲基染料,与许多仪器上的 Cy5 通道兼容。 这是 BDP 650/665 的叠氮化物衍生物。 它可以通过铜催化反应与末端炔烃结合,或通过无铜点击化学与环炔烃结合。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP 650/665 azide

BDP 650/665 azide

标签:Azides,Near infrared (NIR) imaging,BDP 650/665
货号 规格 价格 货期
18430 1 mg 110.00$ in stock
28430 5 mg 210.00$ in stock
38430 10 mg 310.00$ in stock
48430 25 mg 410.00$ in stock
58430 50 mg 695.00$ in stock
68430 100 mg please inquire in stock

BDP 650/665 is a bright red emitting borondipyrromethene dye, compatible with Cy5 channel found on many instruments. This is azide derivative of BDP 650/665. It can be conjugated with terminal alkynes via copper catalyzed reaction, or with cycloalkynes via copper-free Click chemistry.

BDP 650/665 azide can be conjugated with various terminal alkynes using copper-catalyzed Click chemistry, or with cycloalkynes using a copper-free reaction.

BDP 650/665 是一种明亮的红色发光硼二吡咯亚甲基染料,与许多仪器上的 Cy5 通道兼容。 这是 BDP 650/665 的叠氮化物衍生物。 它可以通过铜催化反应与末端炔烃结合,或通过无铜点击化学与环炔烃结合。

BDP 650/665 叠氮化物可以使用铜催化的点击化学与各种末端炔烃偶联,或使用无铜反应与环炔烃偶联。

BDP 650/665 azide

Absorption and emission spectra of BDP 650/665

BDP 650/665 azide

BDP 650/665 azide相关产品

Pyrene azide 1

Reagent for fluorescent labeling with pyrene polycyclic aromatic hydrocarbon via Click Chemistry.

通过 Click Chemistry 用芘多环芳烃进行荧光标记的试剂。

Alkyne CPG modifier 500

Solid support for the synthesis of 3′-modified oligonucleotides with alkyne group for Click Chemistry.

Cy3.5 azide

Cyanine3.5 azide for biomolecule labeling through Click Chemistry.

为 Click Chemistry 合成具有Cy3′-修饰寡核苷酸提供坚实支持。

General properties

Appearance: dark colored solid
Molecular weight: 515.32
Molecular formula: C26H24N7BF2O2
Solubility: good in DMF, DMSO, low in water
Quality control: NMR 1H, HPLC-MS (95%)
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 649
ε, L⋅mol−1⋅cm−1: 94000
Emission maximum, nm: 667
Fluorescence quantum yield: 0.52
CF260: 0.04
CF280: 0.04

Sulfo-Cy7.5 NHS ester

NHS esters,Near infrared (NIR) imaging,sulfo-Cy7.5,Protein labeling,Sulfo-Cy7.5 是一种用于近红外成像应用的近红外水溶性亲水染料。 该染料的结构和光谱类似于已被批准用于人类多年的吲哚菁绿 (ICG)。 然而,与 ICG 不同,磺基-Cy7.5 含有一个三亚甲基桥,与 ICG 相比,它增加了其量子产率,并且还具有一个连接臂,用于连接蛋白质、肽和其他分子。 该衍生物是用于修饰胺基的 NHS 酯。

  • Products
  • Reactive dyes
  • Dye NHS esters
  • Sulfo-Cyanine7.5 NHS ester

Sulfo-Cy7.5 NHS ester

标签:NHS esters Near infrared (NIR) imaging sulfo-Cyanine7.5 Protein labeling
价格
货号 规格 货期
N6320 1 rxn in stock
16320 1 mg 110.00$ in stock
26320 5 mg 290.00$ in stock
46320 25 mg 690.00$ in stock
56320 50 mg 1190.00$ in stock
66320 100 mg 1850.00$ in stock

Sulfo-Cyanine7.5 is a near infrared water soluble and hydrophilic dye for the NIR imaging applications. The structure and spectra of the dye resemble indocyanine green (ICG) that has been approved for use in humans for years. However, unlike ICG, sulfo-Cyanine7.5 contains a trimethylene bridge that increases its quantum yield compared to ICG, and also has a linker arm for its attachment to proteins, peptides, and other molecules. This derivative is an NHS ester for the modification of amine groups.

Sulfo-Cy7.5 是一种用于近红外成像应用的近红外水溶性亲水染料。 该染料的结构和光谱类似于已被批准用于人类多年的吲哚菁绿 (ICG)。 然而,与 ICG 不同,磺基-Cy7.5 含有一个三亚甲基桥,与 ICG 相比,它增加了其量子产率,并且还具有一个连接臂,用于连接蛋白质、肽和其他分子。 该衍生物是用于修饰胺基的 NHS 酯。

Sulfo-Cyanine7.5 NHS ester Sulfo-Cyanine7.5 NHS ester Sulfo-Cyanine7.5 NHS ester Sulfo-Cyanine7.5 NHS ester

Absorption and emission spectra of sulfo-Cyanine7.5

Sulfo-Cyanine7.5 NHS ester

Sulfo-Cy7.5 NHS ester相关产品

BDP FL NHS ester

Amino-reactive BDP FL, a very bright and photostable dye for fluorescein channel.

氨基反应性 BDP FL,一种非常明亮且光稳定的荧光素通道染料。

Cy3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cy3羧酸。

Sulfo-Cyanine7.5 dicarboxylic acid

Sulfo-Cy7.5 dicarboxylic acid is a bifunctional cyanine dye with two carboxylic acid (COOH) groups. The molecule can be used to construct cross conjugates containing a near infrared emitting fluorophore.

Sulfo-Cy7.5 二羧酸是一种具有两个羧酸 (COOH) 基团的双功能花青染料。 该分子可用于构建含有近红外发射荧光团的交叉偶联物。

General properties

Appearance: dark green solid
Mass spec M+ increment: 950.2
Molecular weight: 1180.47
Molecular formula: C49H48N3K3O16S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 778
ε, L⋅mol−1⋅cm−1: 222000
Emission maximum, nm: 797
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.09

相关文献:

  1. González, M.I.; González-Arjona, M.; Santos-Coquillat, A.; Vaquero, J.; Vázquez-Ogando, E.; de Molina, A.; Peinado, H.; Desco, M.; Salinas, B. Covalently Labeled Fluorescent Exosomes for In Vitro and In Vivo Applications. Biomedicines, 2021, 9, 81. doi: 10.3390/biomedicines9010081
  2. Park, B.G.; Kim, Y.J.; Min, J.H.; Cheong, T.-C.; Nam, S.H.; Cho, N.-H.; Kim, Y.K.; Lee, K.B. Assessment of Cellular Uptake Efficiency According to Multiple Inhibitors of Fe3O4-Au Core-Shell Nanoparticles: Possibility to Control Specific Endocytosis in Colorectal Cancer Cells. Nanoscale Research Letters, 2020, 15, 165. doi: 10.1186/s11671-020-03395-w
  3. Ju, Y.; Guo, H.; Yarber, F.; Edman, M.C.; Peddi, S.; Janga, S.R.; MacKay, J.A.; Hamm-Alvarez, S.F. Molecular Targeting of Immunosuppressants Using a Bi-functional Elastin-Like Polypeptide. Bioconjugate Chemistry, 2019, 30(9), 2358–2372. doi: 10.1021/acs.bioconjchem.9b00462
  4. Ruiz, A.; Bravo, D.; Duarte, A.; Adler, R.S.; Raya, J.G. Accuracy of Ultrasound-Guided versus Landmark-Guided Intra-articular Injection for Rat Knee Joints. Ultrasound in Medicine and Biology, 2019, 45(10), 2787–2796. doi: 10.1016/j.ultrasmedbio.2019.06.403

Sulfo-Cy7 NHS ester

Sulfo-Cy7 NHS ester,水溶性近红外染料 sulfo-Cy7,一种胺反应性琥珀酰亚胺酯。Sulfo-Cy7 是 Cy7® 荧光团的改进类似物,量子产率提高了 20%,光稳定性更高。 这种荧光染料对近红外成像特别有用。

  • Products
  • Reactive dyes
  • Dye NHS esters
  • Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester

标签:sulfo-Cy7 NHS esters Near infrared (NIR) imaging Protein labeling
货号 规格 价格 货期
15320 1 mg 110.00$ in stock
25320 5 mg 290.00$ in stock
45320 25 mg 690.00$ in stock
55320 50 mg 1270.00$ in stock
65320 100 mg 1990.00$ in stock

Water soluble near infrared dye sulfo-Cy7, an amine-reactive succinimide ester.

Sulfo-Cy7 is an improved analog of Cy7® fluorophore with quantum yield improved by 20%, and higher photostability. This fluorescent dye is especially useful for NIR imaging.

Near infrared fluorescent imaging takes advantage of transparency of biological tissues at particular range of wavelengths. The method is non-destructive, and allows to monitor distribution of various labeled molecules in live organisms.

Sulfo-Cyanine7 NHS ester reagent allows to prepare sulfo-Cyanine7-labeled biomolecules, such as proteins, with ease. Dye labeled molecules can be subsequently used for various research and drug design related experiments.

This reagent has high water solubility, and is especially useful for the labeling of delicate proteins, and proteins prone to denaturation. Non-sulfonated Cy7 NHS ester soluble in organic phase is also available.

水溶性近红外染料 sulfo-Cy7,一种胺反应性琥珀酰亚胺酯。

Sulfo-Cy7 是 Cy7® 荧光团的改进类似物,量子产率提高了 20%,光稳定性更高。 这种荧光染料对近红外成像特别有用。

近红外荧光成像利用特定波长范围内生物组织的透明度。 该方法是非破坏性的,可以监测活生物体中各种标记分子的分布。

Sulfo-Cyanine7 NHS 酯试剂可以轻松制备磺基-Cyanine7 标记的生物分子,例如蛋白质。 染料标记的分子随后可用于各种研究和药物设计相关实验。

该试剂具有高水溶性,特别适用于标记精细蛋白质和易于变性的蛋白质。 也可提供可溶于有机相的非磺化 Cy7 NHS 酯。

Sulfo-Cyanine7 NHS ester Sulfo-Cyanine7 NHS ester Sulfo-Cyanine7 NHS ester Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 absorbance and emission spectra

Sulfo-Cyanine7 NHS ester

Sulfo-Cyanine7 NHS ester相关产品

AF430 NHS ester

AF430 is a hydrophilic coumarin dye with the emission in green-yellow range. The NHS ester is used for the labeling of amine groups.
AF430 是一种亲水性香豆素染料,发射在黄绿色范围内。 NHS 酯用于标记胺基。

Cyanine5 alkyne

Cyanine5 alkyne is an alkyne dye for Click Chemistry.
Cy5 炔烃是一种用于 Click Chemistry 的炔烃染料。

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.
Pico488 是一种染料,用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光,在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。

General properties

Appearance: dark green powder
Molecular weight: 844.05
CAS number: 1603861-95-5 (potassium salt); 1604244-45-2 (inner salt); 477908-53-5 (N-Ethyl)
Molecular formula: C41H46N3KO10S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 240600
Emission maximum, nm: 773
Fluorescence quantum yield: 0.24
CF260: 0.04
CF280: 0.04

相关文献:

  1. do Valle Gomes, M.Z.; Masdeu, G.; Eiring, P.; Kuhlemann, A.; Sauer, M.; Åkerman, B:; Palmqvist, A.E.C. Improved biocatalytic cascade conversion of CO2 to methanol by enzymes Co-immobilized in tailored siliceous mesostructured cellular foams. Catalysis Science & Technology, 2021, 11(21), 6952–6959. doi: 10.1039/D1CY01354H
  2. Trac, N.; Chen, L.-Y.; Zhang, A.; Liao, C.-P.; Poon, C.; Wang, J.; Ando, Y.; Joo, J.; Garri, C.; Shen, K.; Kani, K.; Gross, M.E.; Chung, E.J. CCR2-targeted micelles for anti-cancer peptide delivery and immune stimulation. Journal of Controlled Release, 2021, 329, 614–623. doi: 10.1016/j.jconrel.2020.09.054
  3. González, L.F.; Acuña, E.; Arellano, G.; Morales, P.; Sotomayor, P.; Oyarzun-Ampuero, F.; Naves, R. Intranasal delivery of interferon-β-loaded nanoparticles induces control of neuroinflammation in a preclinical model of multiple sclerosis: A promising simple, effective, non-invasive, and low-cost therapy. Journal of Controlled Release, 2021, 331, 443–459. doi: 10.1016/j.jconrel.2020.11.019
  4. Shapoval, O.; Oleksa, V.; Šlouf, M.; Lobaz, V.; Trhlíková, O.; Filipová, M.; Janoušková, O.; Engstová, H.; Pankrác, J.; Modrý, A.; Herynek, V.; Ježek, P.; Šefc, L.; Horák, D. Colloidally Stable P(DMA-AGME)-Ale-Coated Gd(Tb)F3:Tb3+(Gd3+),Yb3+,Nd3+ Nanoparticles as a Multimodal Contrast Agent for Down- and Upconversion Luminescence, Magnetic. Nanomaterials, 2021, 11(1), 230. doi: 10.3390/nano11010230
Cy® is a trademark of GE Healthcare.