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MIG Bovine
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MIG Bovine Recombinant
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CHM-041
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Catalogue number
CHM-041
Synonyms
Small inducible cytokine B9, CXCL9, Gamma INF-induced monokine, MIG, chemokine ligand 9, CMK, Humig, SCYB9, crg-10, monokine induced by gamma-INF.
Introduction
Chemokine ligand 9 is a small cytokine belongs to the CXC chemokine family that is also known as Monokine induced by gamma INF . CXCL9 is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.
趋化因子配体 9 是一种小细胞因子,属于 CXC 趋化因子家族,也称为由 γ INF 诱导的 Monokine。 CXCL9 与另外两种称为 CXCL10 和 CXCL11 的 CXC 趋化因子密切相关,它们的基因位于人类 4 号染色体上的 CXCL9 基因附近。CXCL9、CXCL10 和 CXCL11 都通过与趋化因子受体 CXCR3 相互作用而引发其趋化功能。
Description
MIG BovineRecombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 104 amino acids and having a molecular mass of approximately 18.0kDa.
MIG is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB and 500mM NaCl, pH 7.0.
Solubility
It is recommended to reconstitute the lyophilized MIG in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability
Lyophilized MIG although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution MIG should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.
Purity
Greater than 96.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.
Amino acid sequence
VPAIRNGRCS CINTSQGMIH PKSLKDLKQF APSPSCEKTE IIATMKNGNE ACLNPDLPEV KELIKEWEKQ VNQKKKQRKG KKYKKTKKVP KVKRSQRPSQ KKTT.
Biological Activity
The biological activity determined by a chemotaxis bioassay using human lymphocytes is 0.1-1.0 ng/ml.
Usage
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