标签： MIG 小鼠重组CHM-337

Small inducible cytokine B9, CXCL9, MIG, chemokine ligand 9, CMK, Humig, SCYB9, crg-10, M119.

Chemokine ligand 9 is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by MIG. CXCL9 is a T-cell chemoattractant. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.

趋化因子配体 9 是一种小细胞因子，属于 CXC 趋化因子家族，也称为 MIG 诱导的 Monokine。 CXCL9 是一种 T 细胞趋化剂。 它与另外两种称为 CXCL10 和 CXCL11 的 CXC 趋化因子密切相关，它们的基因位于人类 4 号染色体上的 CXCL9 基因附近。CXCL9、CXCL10 和 CXCL11 都通过与趋化因子受体 CXCR3 相互作用而引发其趋化功能。

MIG Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 105 amino acids and having a molecular mass of 12208 Dalton. The MIG is purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 MIG Mouse Recombinant 是单一的、非糖基化的多肽链，包含 105 个氨基酸，分子量为 12208 道尔顿。 MIG 通过专有的色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Filtered and lyophilized from a concentrated solution in 20mM PB, pH7.4 and 100mM NaCl.

It is recommended to reconstitute the lyophilized MIG in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Lyophilized MIG although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL9 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.

The sequence of the first five N-terminal amino acids was determined and was found to be, Thr-Leu-Val-Ile-Arg.

The Activity is calculated by the ability to chemoattract Human lymphocytes using a concentration of 0.1-1 ng/ml.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.