标签： Microscopy

BDP 630/650 X NHS ester

BDP 630/650 X NHS ester,BDP 630/650 是一种硼二吡咯亚甲基荧光团，具有高摩尔消光系数、出色的量子产率和相对较长的激发态寿命。 因此，这种荧光团可用于荧光偏振测定，以检测分子之间的结合。

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  • BDP 630/650 X NHS ester

BDP 630/650 X NHS ester

标签：NHS esters Fluorescence polarization Microscopy BDP 630/650 Protein labeling
货号 规格 价格 货期
15420 1 mg 110.00$ in stock
25420 5 mg 210.00$ in stock
45420 25 mg 410.00$ in stock
55420 50 mg 695.00$ in stock
65420 100 mg 1190.00$ in stock

BDP 630/650 is a borondipyrromethene fluorophore that has a high molar extinction coefficient, excellent quantum yield, and a relatively long lifetime of the excited state. Due to it, this fluorophore is useful for fluorescence polarization assays that allow to detect binding between molecules.

This is an amine reactive NHS ester. It contains an aminohexanoyl linker between the fluorophore and the reactive group.

BDP 630/650 是一种硼二吡咯亚甲基荧光团，具有高摩尔消光系数、出色的量子产率和相对较长的激发态寿命。 因此，这种荧光团可用于荧光偏振测定，以检测分子之间的结合。

这是一种胺反应性 NHS 酯。 它在荧光团和反应基团之间包含一个氨基己酰基接头。

BDP 630/650 X NHS ester BDP 630/650 X NHS ester BDP 630/650 X NHS ester BDP 630/650 X NHS ester

Absorption and emission spectra of BDP 630/650

BDP 630/650 X NHS ester

BDP 630/650 X NHS ester相关产品

BDP TR X NHS ester

BDP TR X NHS ester is a derivative of BDP TR containing a long linker based on aminohexanoic acid (C6). The dye has absorption and emission close to ROX. The NHS ester function can be used for the conjugation with proteins and peptides.

BDP TR X NHS 酯是 BDP TR 的衍生物，含有一个基于氨基己酸 (C6) 的长接头。 该染料具有接近ROX的吸收和发射。 NHS 酯功能可用于与蛋白质和肽的结合。

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪（甲基四嗪）用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

dsGreen for Real-Time PCR, 100×

Stock solution of dsGreen for Real-Time PCR, 100×

用于实时 PCR 的 dsGreen 储备溶液，100×

General properties

Appearance: dark colored solid
Mass spec M+ increment: 545.2
Molecular weight: 660.5
CAS number: 2213445-35-1; 380367-48-6
Molecular formula: C33H31N4BF2O6S
IUPAC name: Succinimidyl-6-[2-(p-{(E)-2-[4,4-difluoro-5-(2-thienyl)-3a,4a-diaza-4-bora-s-indacen-3-yl]ethenyl}phenoxy)acetylamino]hexanoate
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

相关文献：

  1. Grätz, L.; Tropmann, K.; Bresinsky, M.; Müller, C.; Bernhardt, G.; Pockes, S. NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports, 2020, 10, 13288. doi: 10.1038/s41598-020-70332-3
  2. Gruber, C.G.; Pegoli, A.; Müller, C.; Grätz, L.; She, X.; Keller, M. Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity. RSC Medicinal Chemistry, 2020, 11(7), 823–832. doi: 10.1039/D0MD00137F
  3. Zhong, X.; Shtukenberg, A.G.; Liu, M.; Olson, I.A.; Weck, M.; Ward, M.D.; Kahr, B. Dislocation Generation by Microparticle Inclusions. Crystal Growth & Design, 2019, 19(11), 6649–6655. doi: 10.1021/acs.cgd.9b01041

BDP 630/650 X NHS ester

BDP 576/589 NHS ester

BDP 576/589 NHS ester,BDP 576/589（BODIPY™ 576/589 类似物）是一种硼二吡咯亚甲基染料。 这种疏水染料具有高量子产率和长激发态寿命（约 5 纳秒）。 它可用于测量荧光寿命和荧光偏振以及双光子激光扫描显微镜。

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  • BDP 576/589 NHS ester

BDP 576/589 NHS ester

标签：NHS esters Fluorescence polarization Microscopy BDP 576/589
Cat. # Quantity Price Lead time
1G420 1 mg 110.00$ in stock
2G420 5 mg 210.00$ in stock
4G420 25 mg 410.00$ in stock
5G420 50 mg 695.00$ in stock
6G420 100 mg 1190.00$ 7 days

BDP 576/589 (a BODIPY™ 576/589 analog) is a boron dipyrromethene dye. This hydrophobic dye has high quantum yield and long excited-state lifetime (about 5 nanoseconds). It can be used for measuring fluorescence lifetime and fluorescence polarization and in two-photon laser scanning microscopy.

This reagent is an activated N-hydroxysuccinimide ester of the dye with reactivity to primary and secondary amino groups.

BDP 576/589（BODIPY™ 576/589 类似物）是一种硼二吡咯亚甲基染料。 这种疏水染料具有高量子产率和长激发态寿命（约 5 纳秒）。 它可用于测量荧光寿命和荧光偏振以及双光子激光扫描显微镜。

该试剂是染料的活化 N-羟基琥珀酰亚胺酯，对伯氨基和仲氨基具有反应性。

BDP 576/589 NHS ester BDP 576/589 NHS ester BDP 576/589 NHS ester BDP 576/589 NHS ester

BDP 576/589 NHS ester相关产品

BDP TR X NHS ester

BDP TR X NHS ester is a derivative of BDP TR containing a long linker based on aminohexanoic acid (C6). The dye has absorption and emission close to ROX. The NHS ester function can be used for the conjugation with proteins and peptides.
BDP TR X NHS 酯是 BDP TR 的衍生物，含有一个基于氨基己酸 (C6) 的长接头。 该染料具有接近ROX的吸收和发射。 NHS 酯功能可用于与蛋白质和肽的结合。

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.
香豆素 343 是一种蓝色发射染料，可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性，以及染料和官能团之间的空间分离。

FAM amine, 5-isomer

Amino derivative of fluorescein, pure 5-isomer. Contains a linker arm between the aliphatic amine group, and the fluorophore. Useful for the labeling via enzymatic transamination, for the reactions with electrophilic reagents, and for reductive amination.
荧光素的氨基衍生物，纯 5-异构体。 在脂肪胺基团和荧光团之间包含一个连接臂。 可用于通过酶促氨基转移进行标记、与亲电子试剂的反应以及还原胺化。

General properties

Appearance: dark colored crystals
Mass spec M+ increment: 328.1
Molecular weight: 426.18
CAS number: 201998-61-0
Molecular formula: C20H17N4BF2O4
Solubility: soluble in polar organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 580
ε, L⋅mol−1⋅cm−1: 98000
Emission maximum, nm: 592
Fluorescence quantum yield: 0.13

AF568 NHS ester/AF568 NHS 酯

AF568 NHS ester/AF568 NHS 酯,AF568是一种合成荧光团。AF568的激发峰位于572 nm，发射峰位于598 nm。AF568 NHS ester,AF568,lumiprobe代理,lumiprobe产品

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  • AF568 NHS ester

AF568 NHS ester

标签:
货号 规格 价格 货期
14820 1 mg 110.00$ in stock
24820 5 mg 290.00$ in stock
44820 25 mg 690.00$ in stock
54820 50 mg 1270.00$ in stock
64820 100 mg 1990.00$ in stock

AF568 is a synthetic fluorophore. The excitation peak of AF568 lies at 572 nm and its emission peak is at 598 nm. It can be excited using a 561 nm laser. AF568 is spectrally similar to  TF4 (Tide Fluor™ 4), and sulfo-Cyanine3.5 dyes.
AF568是一种合成荧光团。AF568的激发峰位于572 nm，发射峰位于598 nm。它可以用561纳米激光激发。AF568在光谱上与TF4（Tide Fluor）相似™4）和磺基氰3.5种染料。

As AF568 NHS Ester can be conjugated with proteins and peptides, it is recommended for stable signal generation in imaging, including Western Blotting, fluorescence microscopy, and flow cytometry.
由于AF568 NHS酯可以与蛋白质和肽结合，因此建议在成像中产生稳定的信号，包括免疫印迹、荧光显微镜和流式细胞术。

AF568 NHS ester AF568 NHS ester AF568 NHS ester AF568 NHS ester

Absorption and emission spectra of AF568

AF568 NHS ester

AF568 NHS ester相关产品

BDP 581/591 NHS ester

NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.
BDP 581/591硼二吡咯烷荧光团的NHS酯衍生物，用于标记蛋白质、肽和其他生物分子。该染料可用于荧光偏振和双光子实验，并可作为活性氧探针。

AF430 azide

Azide derivative of AF430 for labeling and detection of alkyne-containing biomolecules via Click chemistry reaction

AF430 NHS ester

AF430 is a hydrophilic coumarin dye with the emission in green-yellow range. The NHS ester is used for the labeling of amine groups.

General properties

Appearance: dark colored solid
Mass spec M+ increment: 676.1
Molecular weight: 994.18
Molecular formula: C49H63N5O13S2
Solubility: good in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 572
ε, L⋅mol−1⋅cm−1: 94238
Emission maximum, nm: 598
Fluorescence quantum yield: 0.912
CF260: 0.4
CF280: 0.32
Tide Fluor™ is a trademark of AAT Bioquest.

AF488 NHS ester/AF488 NHS 酯

AF488 NHS ester/AF488 NHS 酯,AF488 NHS ester,AF488是一种明亮且耐光的染料。由于其高亲水性，这是敏感蛋白质和抗体标记的首选染料。lumiprobe代理,lumiprobe产品

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  • AF488 NHS ester

AF488 NHS ester

标签: ,,
货号 规格 价格 货期
11820 1 mg 110.00$ in stock
21820 5 mg 290.00$ in stock
41820 25 mg 690.00$ in stock
51820 50 mg 1270.00$ in stock
61820 100 mg 1990.00$ in stock

AF488 is a bright and photostable dye. Due to its high hydrophilicity, this is a dye of choice for the labeling of sensitive proteins and antibodies. The dye is useful for many demanding applications, including microscopy.

AF488是一种明亮且耐光的染料。由于其高亲水性，这是敏感蛋白质和抗体标记的首选染料。这种染料适用于许多苛刻的应用，包括显微镜。

From the chemical standpoint, AF488 is a sulfonated rhodamine dye Rhodamine 110 (R110). Like other rhodamines, it is available as 5- and 6-isomers, which have almost identical photophysical properties.

从化学角度来看，AF488是磺化罗丹明染料罗丹明110（R110）。与其他罗丹明类似，它可以作为5-和6-异构体，具有几乎相同的光物理性质。

The isomers need to be separated though – otherwise, use of mixed isomer dye can lead to doubled peaks during HPLC or electrophoresis separations of the labeled products. This product is an isomerically pure 5-AF488.

但是，异构体需要分离——否则，使用混合异构体染料可能会在标记产品的HPLC或电泳分离过程中导致双峰。本品为同分异构体纯5-AF488。

This NHS ester is an amine reactive dye, it can label amine groups in proteins, peptides, amino-modified oligos, and other target molecules.

这种NHS酯是一种胺活性染料，它可以标记蛋白质、肽、氨基修饰低聚物和其他目标分子中的胺基。

AF488 NHS ester AF488 NHS ester AF488 NHS ester AF488 NHS ester

Absorption and emission spectra of AF488

AF488 NHS ester

AF488 NHS ester 相关产品

DMF (dimethylformamide), labeling grade

Dry high purity amine free solvent for NHS ester labeling.
干燥高纯度无胺溶剂，用于NHS酯标记。

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.
胺反应性菁5活化酯，用于标记蛋白质、肽和其他分子。

Cyanine5.5 DBCO

Cyanine5.5 is a far-red / NIR emitting dye that is useful for bioimaging studies. Cyanine5.5 DBCO is a derivative of the dye with a cycloalkyne moiety for Copper free Click chemistry.
氰基5。5是一种远红色/近红外发光染料，可用于生物成像研究。氰基5。5 DBCO是该染料的衍生物，具有无铜点击化学的环炔部分。

General properties

Appearance: dark orange solid
Molecular weight: 732.74
Molecular formula: C31H32N4O13S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (80+%, balance mostly carboxylic acid)
Storage conditions: Storage: 12 months after receipt at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 495
ε, L⋅mol−1⋅cm−1: 71800
Emission maximum, nm: 519
Fluorescence quantum yield: 0.91
CF260: 0.16
CF280: 0.10

H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate)

H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate),H2DCFDA（2′,7′-二氯二氢荧光素二乙酸酯）是一种常用试剂，用于研究活细胞中活性氧的产生。

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  • H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate)

H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate)

标签：FAM (Fluorescein),Microscopy
货号 规格 价格 货期
2247-10mg 10 mg – 10 days
2247-100mg 100 mg 110.00$ in stock
2247-250mg 250 mg 190.00$ in stock

H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate) is a common reagent used for investigating the production of reactive oxygen species in living cells.

H2DCFDA is a non-fluorescent fluorescein derivative (its reduced acetylated form). The reagent begins to emit fluorescence only after cleavage of acetyl groups and the reagent’s oxidation in the cell while converting to 2’,7’-dichlorofluorescein. This is a bright green-fluorescent dye (absorption maximum 511 nm, fluorescence maximum 533 nm). This reagent can be used for assays in living cells and is not compatible with sample fixation.

Acetyl groups in H2DCFDA increase its lipophilicity and improve its cell membrane permeability. Once got into the cell, the dye is deacetylated by cell esterases, thus becoming charged and better fixed inside the cell. Oxidation with reactive oxygen forms results in the formation of a fluorescent product (2’,7’-dichlorofluorescein) and can be detected using various methods, for example with a flow cytometer, plate reader, or fluorescent microscope.

H2DCFDA（2′,7′-二氯二氢荧光素二乙酸酯）是一种常用试剂，用于研究活细胞中活性氧的产生。

H2DCFDA 是一种非荧光荧光素衍生物（其还原乙酰化形式）。该试剂仅在乙酰基裂解和试剂在细胞中氧化并转化为 2′,7′-二氯荧光素后才开始发射荧光。这是一种亮绿色荧光染料（最大吸收 511 nm，最大荧光 533 nm）。该试剂可用于活细胞检测，与样品固定不兼容。

H2DCFDA 中的乙酰基会增加其亲脂性并改善其细胞膜通透性。一旦进入细胞，染料就会被细胞酯酶脱乙酰化，从而带电并更好地固定在细胞内。用活性氧形式氧化会形成荧光产物（2′,7′-二氯荧光素），可以使用各种方法检测，例如使用流式细胞仪、读板器或荧光显微镜。

Recommendations for using the reagent使用试剂的建议：:

  • Use a freshly prepared solution of the reagent (the working solution is not intended for long-term storage because of gradual reagent oxidation).
  • Select an optimal working concentration of the reagent and incubation time required for reagent deacetylation and oxidation for the specific cell line and assay conditions. If there are no protocols recommended for the specific cell line, start with a concentration from 1 to 10 µM and incubation for 30 min.
  • Do not incubate the dye with the cells in the presence of serum because it contains enzymes that cleave H2DCFDA.
  • 使用新配制的试剂溶液（工作溶液不适合长期储存，因为试剂会逐渐氧化）。
    针对特定细胞系和测定条件，选择试剂脱乙酰和氧化所需的最佳试剂工作浓度和孵育时间。 如果没有针对特定细胞系推荐的方案，请从 1 到 10 µM 的浓度开始并孵育 30 分钟。
    不要在存在血清的情况下将染料与细胞一起孵育，因为它含有切割 H2DCFDA 的酶。

H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate) H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate) H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate) H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate)

H2DCFDA absorbance and emission spectra

H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate)

H2DCFDA (2′,7′-dichlorodihydrofluorescein diacetate)相关产品

Cyanine5 NHS ester

Amine-reactive Cyanine5 activated ester for the labeling of proteins, peptides, and other molecules.

胺反应性 Cy5 活化酯，用于标记蛋白质、肽和其他分子。

Cyanine5 DBCO

Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper free Click chemistry.

用于无铜点击化学的具有二苯并环辛炔 (DBCO) 官能团的 Cy5 染料。

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cy7.5的胺反应性NHS酯。

General properties

Appearance: colorless solid
Molecular weight: 487.29
CAS number: 4091-99-0
Molecular formula: C24H16Cl2O7
IUPAC name: 2-(3,6-diacetyloxy-2,7-dichloro-9H-xanthen-9-yl)benzoic acid
Solubility: good in DMSO, ethanol, and DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: 12 months from delivery at −20°C protected from light. Transportation: Up to 3 weeks at room temperature. Protect from moisture. Avoid storage unprotected from light and unnecessary freeze-thaw cycles of the stock solution. If the reagent is used several times, it is strongly recommended to store it in an atmosphere of dry argon or nitrogen.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 511
ε, L⋅mol−1⋅cm−1: 118626
Emission maximum, nm: 533
CF260: 0.17
CF280: 0.14

AF430 tetrazine

AF430 tetrazine,AF430 是一种荧光染料。 AF430 在 430 nm 处具有最大激发，在 542 nm 处具有最大发射。 AF430 是为数不多的在 400 nm 和 450 nm 之间吸收的染料之一。 AF430 荧光在广泛的 pH 值范围内具有光稳定性和 pH 不敏感性。

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  • AF430 tetrazine

AF430 tetrazine

标签：Tetrazine, Microscopy, AF430
货号 规格 价格 货期
108E0 1 mg 110.00$ in stock
208E0 5 mg 290.00$ in stock
308E0 10 mg 460.00$ in stock
408E0 25 mg 690.00$ in stock
508E0 50 mg 1270.00$ in stock
608E0 100 mg 1990.00$ in stock

AF430 is a fluorescent dye. AF430 has an excitation maximum at 430 nm and an emission maximum at 542 nm. AF430 is one of the few dyes that absorb between 400 nm and 450 nm. AF430 fluorescence is photostable and pH-insensitive in a broad range of pH values.

Tetrazine residue participates in the fast copper-free click reaction that is well suited to non-toxic in vitro cell labeling and low-concentration applications.

AF430 是一种荧光染料。 AF430 在 430 nm 处具有最大激发，在 542 nm 处具有最大发射。 AF430 是为数不多的在 400 nm 和 450 nm 之间吸收的染料之一。 AF430 荧光在广泛的 pH 值范围内具有光稳定性和 pH 不敏感性。

四嗪残基参与快速无铜点击反应，非常适合无毒的体外细胞标记和低浓度应用。

Absorption and emission spectra of AF430

AF430 tetrazine

AF430 tetrazine相关产品

Cyanine5 tetrazine

Cyanine5 is a universal red emitting dye with a very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.

Cy5 是一种通用的红色发光染料，具有非常高的消光系数和良好的量子产率。 这种四嗪衍生物与反式环辛烯和环丙烯反应非常迅速，形成稳定的共轭物。

AmdU (5-azidomethyl-2′-deoxyuridine)

Azidomethyldeoxyuridine (AmdU) is an azide containing nucleoside that is incorporated into nascent DNA by cellular polymerases. The azide groups attached to DNA this way can be subsequently modified with alkynes or cycloalkynes via copper-catalyzed or strain promoted Click chemistry.

叠氮甲基脱氧尿苷 (AmdU) 是一种含有核苷的叠氮化物，可通过细胞聚合酶整合到新生 DNA 中。 以这种方式连接到 DNA 上的叠氮基可以随后通过铜催化或应变促进的点击化学被炔烃或环炔烃修饰。

BDP FL tetrazine

BDP FL tetrazine (methyltetrazine) is a reactive dye for the inverse electron demand Diels-Alder (ied-DA) reaction with trans-cyclooctenes, cyclopropenes, and other strained cycloolefines. BDP FL is a bright and photostable dye for the 488 nm fluorescein (FAM) channel.

BDP FL 四嗪（甲基四嗪）是一种活性染料，用于与反式环辛烯、环丙烯和其他应变环烯烃进行逆电子需求 Diels-Alder (ied-DA) 反应。 BDP FL 是一种用于 488 nm 荧光素 (FAM) 通道的明亮且光稳定的染料。

General properties

Appearance: dark orange solid 深橙色固体
Mass spec M+ increment: 658.2
Molecular weight: 724.79
Molecular formula: C32H32N6F3KO6S
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 430
ε, L⋅mol−1⋅cm−1: 15955
Emission maximum, nm: 542
Fluorescence quantum yield: 0.23
CF260: 0.06
CF280: 0.06

BDP TMR amine

BDP TMR amine,BDP TMR 是 TAMRA 通道的染料。 然而，与原始 TAMRA 不同，它具有非常好的量子产率，因此具有高亮度。

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BDP TMR amine

标签：Amines, Fluorescence polarization, Microscopy, BDP TMR
货号 规格 价格 货期
124C0 1 mg 110.00$ in stock
224C0 5 mg 210.00$ in stock
424C0 25 mg 410.00$ in stock
524C0 50 mg 695.00$ in stock
624C0 100 mg 1190.00$ in stock

BDP TMR is a dye for TAMRA channel. Unlike original TAMRA, it however possesses very good quantum yield, and therefore high brightness.

This derivative contains a primary amine group that can be conjugated with various electrophiles. It can also participate in enzymatic transamination reaction.

BDP TMR 是 TAMRA 通道的染料。 然而，与原始 TAMRA 不同，它具有非常好的量子产率，因此具有高亮度。

该衍生物含有一个伯胺基团，可以与各种亲电子试剂共轭。 还可参与酶促转氨反应。

Absorption and emission spectra of BODIPY TMR

BDP TMR amine

BDP TMR amine相关产品

BDP 581/591 amine

BDP 581/591 fluorophore derivative with free amine group for the conjugation with electrophilic reagents, and enzymatic transamination.

BDP 581/591 具有游离胺基团的荧光团衍生物，用于与亲电试剂偶联和酶促转氨。

Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cyanine5.5 是一种远红/近红外荧光团，具有高亲水性和水溶性。 由于出色的摩尔消光系数，该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cyanine3 染料 NHS 酯。

General properties

Appearance: violet solid 紫罗兰色固体
Molecular weight: 532.86
CAS number: 2183473-08-5 (free base)
Molecular formula: C27H36BClF2N4O2
IUPAC name: 1,3-dimethyl-2(6-aminohexylaminocarbonyl)-4,4-difluoro-5-(4-methoxyphenyl)borondipyrromethene
Solubility: good in alcohols, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16

BDP 564/570 carboxylic acid

BDP 564/570 carboxylic acid,BDP 564/570 是一种荧光团，在光谱的橙色部分发射。 染料非常疏水。 它可用于标记脂质、寡核苷酸、肽和许多其他大分子和小分子。

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  • BDP 564/570 carboxylic acid

BDP 564/570 carboxylic acid

标签：Carboxylic acids, Microscopy, BDP 564/570
货号 规格 价格 货期
1H490 1 mg 110.00$ in stock
2H490 5 mg 210.00$ in stock
4H490 25 mg 410.00$ in stock
5H490 50 mg 695.00$ in stock
6H490 100 mg 1190.00$ in stock

BDP 564/570 is a fluorophore with the emission in orange part of the spectrum. The dye is pretty hydrophobic. It can be used for the labeling of lipids, oligonucleotides, peptides, and many other large and small molecules.

Free carboxylic acid can be used in peptide synthesis as an N-terminal monomer. An NHS ester, with a pre-activated carboxy group, is also available.

BDP 564/570 是一种荧光团，在光谱的橙色部分发射。 染料非常疏水。 它可用于标记脂质、寡核苷酸、肽和许多其他大分子和小分子。

游离羧酸可作为 N 端单体用于肽合成。 也可提供具有预活化羧基的 NHS 酯。

Absorption and emission spectra of BDP 564/570

BDP 564/570 carboxylic acid

BDP 564/570 carboxylic acid相关产品

BDP FL carboxylic acid

Borondipyrromethene dye for fluorescein (FAM) channel, free unactivated carboxylic acid useful as a negative control, and for the calibration.

用于荧光素 (FAM) 通道的硼二吡咯亚甲基染料、可用作阴性对照的游离未活化羧酸以及用于校准。

BDP 564/570 NHS ester

Lypohilic borodipyrromethene dye with orange emission for the labeling of primary and secondary amine groups.

具有橙色发射的亲液性硼二吡咯亚甲基染料，用于标记伯胺和仲胺基团。

General properties

Appearance: dark colored solid 深色固体
Molecular weight: 366.17
CAS number: 150173-89-0
Molecular formula: C20H17N2BF2O2
Solubility: good in DMF, DMSO, chlorinated organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 565
ε, L⋅mol−1⋅cm−1: 110000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.74
CF260: 0.01
CF280: 0.03

Sulfo-Cyanine3 hydrazide

Sulfo-Cyanine3 hydrazide,Sulfo-Cy3 是 Cy3 染料的硫酸化衍生物，由于其结构中有两个带负电荷的磺基，因此可很好地溶于水。根据其光谱特性，这种橙黄色荧光染料是 Cy™3 的类似物。

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  • Sulfo-Cyanine3 hydrazide

Sulfo-Cyanine3 hydrazide

标签：Hydrazides, Microscopy, sulfo-Cyanine3,Cy3
货号 规格 价格 货期
11370 1 mg 110.00$ in stock
21370 5 mg 290.00$ in stock
41370 25 mg 690.00$ in stock
51370 50 mg 1270.00$ in stock
61370 100 mg 1990.00$ in stock

Sulfo-Cyanine3 is a sulfated derivative of Cyanine3 dye, well soluble in water because of two negatively charged sulfo groups in its structure. By its spectral characteristics, this yellow-orange fluorescent dye is an analog of Cy™3.

Hydrazides efficiently react with aldehydes and ketones resulting in hydrazones, so this compound can be used for conjugation with carbonyl derivatives of biomolecules.

The reaction runs in aqueous conditions, which is important when working with antibodies and proteins. Cys-diol groups in sugars in glycosylated proteins and antibodies can be oxidized into dialdehydes, and cysteine in proteins can be converted with enzymes to formyl glycerol (i. e. reactive groups for conjugation with Sulfo-Cyanine3 hydrazide). Carboxyl groups of aspartic and glutamic acids in proteins and peptides can be also conjugated with Sulfo-Cyanine3 hydrazide in the presence of activating agents: carbodiimide (EDAC) or methyl morpholine (DMTMM) derivatives.

Sulfo-Cy3 是 Cy3 染料的硫酸化衍生物，由于其结构中有两个带负电荷的磺基，因此可很好地溶于水。根据其光谱特性，这种橙黄色荧光染料是 Cy™3 的类似物。

酰肼有效地与醛和酮反应生成腙，因此该化合物可用于与生物分子的羰基衍生物缀合。

反应在水性条件下进行，这在处理抗体和蛋白质时很重要。糖基化蛋白质和抗体中的糖中的 Cys-二醇基团可被氧化成二醛，蛋白质中的半胱氨酸可被酶转化为甲酰基甘油（即与磺基花青 3 酰肼结合的反应基团）。蛋白质和肽中的天冬氨酸和谷氨酸的羧基也可以在活化剂存在的情况下与磺基花青 3 酰肼结合：碳二亚胺 (EDAC) 或甲基吗啉 (DMTMM) 衍生物。

Absorption and emission spectra of sulfo-Cyanine3

Sulfo-Cyanine3 hydrazide

Sulfo-Cyanine3 hydrazide相关产品

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

用于氨基生物分子标记的水溶性磺基-Cy3 SE 活化酯。

Cyanine3 hydrazide

Cyanine3 hydrazide is a carbonyl-reactive dye for Cy3 channel.

Cy3 hydrazide 是 Cy3 通道的羰基反应性染料。

General properties

Appearance: dark red solid 暗红色固体
Molecular weight: 630.78
CAS number: 2144762-62-7
Molecular formula: C30H38N4O7S2
IUPAC name: 3H-​Indolium, 2-​[3-​[1-​(6-​hydrazinyl-​6-​oxohexyl)​-​1,​3-​dihydro-​3,​3-​dimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene]​-​1-​propen-​1-​yl]​-​1,​3,​3-​trimethyl-​5-​sulfo-​, inner salt
Solubility: soluble in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (90%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06
Cy™ is a registered trademark of Cytiva in some countries.

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide,Cy5.5 hydrazide 是一种羰基反应性近红外染料。酰肼与醛和酮等羰基化合物快速反应，形成稳定的腙。该反应可用于制备标记的偶联物。

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Cyanine5.5 hydrazide

标签：Cyanine5.5, Cy5.5,Hydrazides, Microscopy
货号 规格 价格 货期
17070 1 mg 110.00$ in stock
27070 5 mg 210.00$ in stock
47070 25 mg 410.00$ in stock
57070 50 mg 695.00$ in stock
67070 100 mg 1190.00$ in stock

Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.

Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies.

Cyanine5.5 is a near infrared fluorophore, an analog of Cy5.5®. It is particularly suitable for the applications which require low fluorescence background. The absorption and emission wavelength of the dye exhibit significant tissue penetration, so Cyanine5.5 is suitable for in vivo NIR imaging applications.

Cy5.5 hydrazide 是一种羰基反应性近红外染料。酰肼与醛和酮等羰基化合物快速反应，形成稳定的腙。该反应可用于制备标记的偶联物。

生物分子中的羰基可以在氧化应激或蛋白质脱氨基后自发形成。或者，醛基可以通过糖蛋白（例如抗体）的糖残基的高碘酸氧化特异性地产生。抗体可被高碘酸钠氧化，并用Cyanine5.5酰肼标记，形成Cyanine5.5标记的抗体。由于抗体中的糖残基远离可变的表位结合位点，因此该方法特别适用于标记抗体。

Cy5.5 是一种近红外荧光团，是 Cy5.5® 的类似物。它特别适用于需要低荧光背景的应用。染料的吸收和发射波长表现出显着的组织穿透性，因此 Cy5.5 适用于体内近红外成像应用。

Cyanine5.5 absorbance and emission spectra

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide相关产品

Cyanine7 azide

Near-infrared fluorescent dye for Click Chemistry.

用于点击化学的近红外荧光染料。

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FAM azide, 5-isomer

FAM (fluorescein) azide for Click chemistry, pure 5-isomer.

用于点击化学的 FAM（荧光素）叠氮化物，纯 5 异构体。

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Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cy5.5 是一种远红/近红外荧光团，具有高亲水性和水溶性。 由于出色的摩尔消光系数，该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

Cyanine5.5 hydrazide Add this product to your cart and
get free express delivery

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 669.73
Molecular formula: C40H46Cl2N4O
Solubility: practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  2. Zhao, Y.; Wang, Y.; Ran, F.; Cui, Y.; Liu, C.; Zhao, Q.; Gao, Y.; Wang, D.; Wang, S. A comparison between sphere and rod nanoparticles regarding their in vivo biological behavior and pharmacokinetics. Scientific Reports, 2017, 7, 4131. doi: 10.1038/s41598-017-03834-2
Cy® is a trademark of GE Healthcare.

Cyanine5 hydrazide

Cyanine5 hydrazide,Cy5 hydrazide 是一种用于标记醛和酮的活性染料，是 Cy5® 酰肼的类似物。这种染料可以与生物分子中遇到的各种羰基进行平稳且几乎定量的反应。 例子是经受氧化应激的蛋白质、通过高碘酸氧化预活化的糖基化蛋白质（包括抗体）和具有醛部分的寡核苷酸。

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  • Cyanine5 hydrazide

Cyanine5 hydrazide

标签: Cyanine5, Cy5,Hydrazides, Microscopy
货号 规格 价格 货期
13070 1 mg 110.00$ in stock
23070 5 mg 210.00$ in stock
43070 25 mg 410.00$ in stock
53070 50 mg 695.00$ in stock
63070 100 mg 1190.00$ in stock

Cyanine5 hydrazide is a reactive dye for the labeling of aldehydes and ketones, an analog of Cy5® hydrazide.

This dye reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. Examples are proteins subjected to oxidative stress, glycosylated proteins pre-activated by periodate oxidation (including antobodies), and oligonucleotides with aldehyde moieties.

Cyanine5 hydrazide replaces carbonyl-reactive Cy5®, DyLight 649 dyes.

Cy5 hydrazide 是一种用于标记醛和酮的活性染料，是 Cy5® 酰肼的类似物。

这种染料可以与生物分子中遇到的各种羰基进行平稳且几乎定量的反应。 例子是经受氧化应激的蛋白质、通过高碘酸氧化预活化的糖基化蛋白质（包括抗体）和具有醛部分的寡核苷酸。

Cyanine5 酰肼替代羰基反应性 Cy5®、DyLight 649 染料。

Cy5 absorbance and emission spectra

Cyanine5 hydrazide

Cyanine5 hydrazide相关产品

ROX reference dye for qPCR

ROX is a passive reference dye for qPCR amplification. The dye can be used to normalize fluorescence intensity of reporter dye in qPCR.

ROX 是用于 qPCR 扩增的被动参考染料。 该染料可用于标准化 qPCR 中报告染料的荧光强度。

FAM DBCO, 6-isomer

Cyclooctyne derivative of fluorescein (FAM) for copper free Click chemistry reaction with azides. Contains pure 6-isomer of fluorescein.

荧光素 (FAM) 的环辛炔衍生物，用于与叠氮化物的无铜点击化学反应。 含有纯6-异构体的荧光素。

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cy5 azide 是一种用 Cyanine5（一种流行的荧光染料）进行 Click Chemistry 标记的试剂。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 569.61
CAS number: 1427705-31-4
Molecular formula: C32H42Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
  2. Imlimthan, S.; Correia, A.; Figueiredo, P.; Lintinen, K.; Balasubramanian, V.; Airaksinen, A.J.; Kostiainen, M.A.; Santos, H.A.; Sarparanta, M. Systematic In Vitro Biocompatibility Studies of Multimodal Cellulose Nanocrystal and Lignin Nanoparticles. Journal of Biomedical Materials Research. Part A, 2020, 108(3), 770–783. doi: 10.1002/jbm.a.36856
  3. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0
  4. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546
Cy® is a trademark of Cytiva.

Cyanine3 hydrazide

Cyanine3 hydrazide,Cy3 hydrazide 是一种羰基活性染料，是 Cy3® 酰肼的类似物。

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  • Cyanine3 hydrazide

Cyanine3 hydrazide

标签：Cyanine3,Cy3, Hydrazides, Microscopy
货号 规格 价格 货期
11070 1 mg 110.00$ in stock
21070 5 mg 210.00$ in stock
41070 25 mg 410.00$ in stock
51070 50 mg 695.00$ in stock
61070 100 mg 1190.00$ in stock

Cyanine3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide.

This reagent allows to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone oxidative stress or deamination, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.

Cyanine3 hydrazide 是一种羰基活性染料，是 Cy3® 酰肼的类似物。

该试剂可以标记各种含羰基分子，例如高碘酸氧化后的抗体和其他糖蛋白、经历氧化应激或脱氨基作用的蛋白质或还原糖。 Cyanine3 与许多荧光仪器兼容。

Cyanine3 absorbance and emission spectra

Cyanine3 hydrazide

Cyanine3 hydrazide相关产品

BDP TR hydrazide

BDP TR hydrazide for the labeling of carbonyl compounds with BDP TR, a borondipyrromethene matching ROX channel.

BDP TR 酰肼，用于用 BDP TR 标记羰基化合物，BDP TR 是一种匹配 ROX 通道的硼二吡咯亚甲基。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cy3 荧光染料的叠氮化物衍生物。

General properties

Appearance: red powder 红色粉末
Molecular weight: 543.57
Molecular formula: C30H40Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H and HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Zhao, Meng and Börner, Richard and Sigel, Roland K. O. and Freisinger, Eva. Site-Specific Dual-Color Labeling of Long RNAs. Methods in Molecular Biology, 2020, 2106, 253–270. doi: 10.1007/978-1-0716-0231-7_16
  2. Zhang, J.; Chetnani, B.; Cormack, E.D.; Alonso, D.; Liu, W.; Mondragon, A.; Fei, J. Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand. eLife, 2018, 7, e39518. doi: 10.7554/eLife.39518
  3. Cui, Z.; Wu, Y.; Mureev, S.; Alexandrov, K. Oligonucleotide-mediated tRNA sequestration enables one-pot sense codon reassignment in vitro. Nucleic Acids Research, 2018, 46(12), 6387–6400. doi: 10.1093/nar/gky365
  4. Porciani, D.; Cardwell, L.N.; Tawiah, K.d.; Alam, K.K.; Lange, M.J.; Daniels, M.A.; Burke, D.H. Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Nature Communications, 2018, 9(1), 2283. doi: 10.1038/s41467-018-04691-x
Cy® is a trademark of GE Healthcare.

BDP FL hydrazide

BDP FL hydrazide，BDPFL 是一种用于 FAM 通道的明亮且光稳定的染料。 它具有很好的光稳定性，量子产率接近统一。 这种染料非常适合显微镜和荧光偏振测定。

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  • Reactive dyes
  • Dye hydrazides
  • BDP FL hydrazide

BDP FL hydrazide

标签：BDP FL, Hydrazides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
11470 1 mg 110.00$ in stock
21470 5 mg 210.00$ in stock
41470 25 mg 410.00$ in stock
51470 50 mg 695.00$ in stock
61470 100 mg 1190.00$ in stock
BDPFL is a bright and photostable dye for FAM channel. It possesses great photostability, quantum yield approaching unity. This dye is well-suited for microscopy and fluorescence polarization assays.

Hydrazide group provides easy conjugation with carbonyl compounds (aldehydes, and ketones).

BDPFL 是一种用于 FAM 通道的明亮且光稳定的染料。 它具有很好的光稳定性，量子产率接近统一。 这种染料非常适合显微镜和荧光偏振测定。

酰肼基团易于与羰基化合物（醛和酮）结合。

Absorption and emission spectra of BDP FL

BDP FL hydrazide

BDP FL hydrazide相关产品

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

General properties

Appearance: brown to orange solid 棕色至橙色固体
Molecular weight: 342.58
CAS number: 2183473-45-0
Molecular formula: C14H18BClF2N4O
Solubility: poorly soluble in water (20.2 mM = 6.94 g/L), soluble in polar (DMSO, DMF) organic solvents, methanol, moderately soluble in acetonitrile, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receipt at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Roloff, A.; Nirmalananthan-Budau, N.; Rühle, B.; Borcherding, H.; Thiele, T.; Schedler, U.; Resch-Genger, U. Quantification of Aldehydes on Polymeric Microbead Surfaces via Catch and Release of Reporter Chromophores. Analytical Chemistry, 2019, 91(14), 8827–8834. doi: 10.1021/acs.analchem.8b05515
  2. Liu, R.; Vairaprakash, P.; Lindsey, J.S. Self-assembly with fluorescence readout in a free base dipyrrin–polymer triggered by metal ion binding in aqueous solution. New Journal of Chemistry, 2019, 43(24), 9711–9724. doi: 10.1039/c9nj01787a

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide,水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

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  • Reactive dyes
  • Dye maleimides
  • Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide

标签：sulfo-Cyanine5, Cy5,Maleimides, Microscopy
货号 规格 价格 货期
13380 1 mg 110.00$ in stock
23380 5 mg 290.00$ in stock
43380 25 mg 690.00$ in stock
53380 50 mg 1270.00$ in stock
63380 100 mg 1990.00$ in stock

A water soluble, hydrophilic sulfo-Cyanine5 maleimide (Cy5® maleimide analog). We recommend this product for protein labeling, including labeling of antibodies as a perfect replacement for Cy5® maleimide. Labeled proteins can be easily separated from unreacted dye by gel filtration, spin column purification, dialysis, electrophoresis or chromatography.

An analog without sulfo groups, Cyanine5 maleimide, is also available.

水溶性、亲水性磺基-Cyanine5 马来酰亚胺（Cy5® 马来酰亚胺类似物）。 我们推荐该产品用于蛋白质标记，包括标记抗体作为 Cy5® 马来酰亚胺的完美替代品。 通过凝胶过滤、旋转柱纯化、透析、电泳或色谱法，可以很容易地将标记的蛋白质与未反应的染料分离。

也可使用不含磺基的类似物 Cyanine5 马来酰亚胺。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 maleimide

Sulfo-Cyanine5 maleimide相关产品

TAMRA azide, 6-isomer

Pure 6-isomer of tetramethylrhodamine (TAMRA) dye, azide derivative for copper-catalyzed and copper-free Click chemistry reactions with alkynes.

纯 6 异构体的四甲基罗丹明 (TAMRA) 染料，叠氮化物衍生物，用于与炔烃的铜催化和无铜点击化学反应。

ROX NHS ester, 6- isomer

Pure isomer 6-ROX NHS ester for amine labeling.

用于胺标记的纯异构体 6-ROX NHS 酯。

Sulfo-Cyanine5 amine

Sulfonated Cyanine5 amine derivative, for the conjugation with electrophiles, and enzymatic transamination labeling.

磺化的 Cy5 胺衍生物，用于与亲电试剂偶联和酶促转氨标记。

General properties

Appearance: dark blue powder  深蓝色粉末
Molecular weight: 803.00
CAS number: 2242791-82-6
Molecular formula: C38H43KN4O9S2
Solubility: soluble in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Ast, J.; Novak, A.N.; Podewin, T.; Fine, N.H.F.; Jones, B.; Tomas, A.; Birke, R.; Roßmann, K.; Mathes, B:; Eichhorst, J.; Lehmann, M.; Linnemann, A.K.; Hodson, D.J.; Broichhagen, J. An expanded LUXendin color palette for GLP1R detection and visualization in vitro and in vivo. ChemRxiv, preprint. doi: 10.33774/chemrxiv-2021-7rngq
  2. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, in press. doi: 10.1016/j.ab.2020.113895
  3. Bauer, B.W.; Davidson, I.F.; Canena, D.; Wutz, G.; Tang, W.; Litos, G.; Horn, S.; Hinterdorfer, P.; Peters, J.-M. Cohesin mediates DNA loop extrusion by a “swing and clamp” mechanism. Cell, 2021, 184(21), 5448–5464.e22. doi: 10.1016/j.cell.2021.09.016
  4. Hurley, C.M.; Kraut, D.A. Determination of Proteasomal Unfolding Ability. Methods in Molecular Biology, 2021, 2365, 217–244. doi: 10.1007/978-1-0716-1665-9_12
Cy® is a trademark of GE Healthcare.

FAM maleimide, 6-isomer

FAM maleimide, 6-isomer,FAM（荧光素）是一种明亮的荧光团，可与各种荧光检测仪器兼容。 FAM 是一种通用染料，可用于显微镜检查、qPCR 和许多其他方法以及基于 FRET 和荧光偏振的结合测定。

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  • Dye maleimides
  • FAM maleimide, 6-isomer

FAM maleimide, 6-isomer

标签：FAM (Fluorescein), Maleimides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
24180 5 mg – in stock
44180 25 mg 160.00$ in stock
54180 50 mg 270.00$ in stock
64180 100 mg 420.00$ in stock

FAM (fluorescein) is a bright fluorophore which is compatible with various fluorescence detection instruments. FAM is a universal dye that is useful for microscopy, qPCR and many other methods as well as for FRET-based and fluorescence polarization based binding assays.

FAM maleimide is a thiol reactive dye for the labeling of proteins, peptides, and other thiolated molecules.

FAM（荧光素）是一种明亮的荧光团，可与各种荧光检测仪器兼容。 FAM 是一种通用染料，可用于显微镜检查、qPCR 和许多其他方法以及基于 FRET 和荧光偏振的结合测定。

FAM 马来酰亚胺是一种硫醇活性染料，用于标记蛋白质、肽和其他硫醇化分子。

Fluorescein (FAM) absorbance and emission spectra

FAM maleimide, 6-isomer

FAM maleimide, 6-isomer相关产品

BDP FL amine

Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.

BDP FL 染料的氨基衍生物，用于 FAM（荧光素）488 nm 通道的硼二吡咯亚甲基染料。

Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Cy5 hydrazide是醛和酮的活性染料。 它可用于糖部分高碘酸氧化后的糖蛋白的标记。

Cyanine5.5 alkyne

Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.

Cy5.5 炔烃是一种 NIR（近红外）染料叠氮化物，适用于铜催化和无铜点击化学。

General properties

Appearance: yellow solid 黄色固体
Mass spec M+ increment: 498.4
Molecular weight: 498.44
Molecular formula: C27H18N2O8
Solubility: good in DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献:

  1. Woodford, M.R.; Baker-Williams, A.J.; Sager, R.A.; Backe, S.J.; Blanden, A.R.; Hashmi, F.; Kancherla, P.; Gori, A.; Loiselle, D.R.; Castelli, M.; Serapian, S.A.; Colombo, G.; Haystead, T.A.; Jensen, S.M.; Stetler-Stevenson, W.G.; Loh, S.N.; Schmidt, L.S.; Linehan, W.M.; Bah, A.; Bourboulia, D.; Bratslavsky, G.; Mollapour, M. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect. Nature Structural & Molecular Biology, 2021, 28(8), 662–670. doi: 10.1038/s41594-021-00633-2
  2. Nojoumi, S.; Ma, Y.; Schwagerus, S.; Hackenberger, C.P.R.; Budisa, N. In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation. International Journal of Molecular Sciences, 2019, 20(9), 2299. doi: 10.3390/ijms20092299
  3. Sauer, F.; Klemm, T.; Kollampally, R.B.; Tessmer, I.; Nair, R.K.; Popov, N.; Kisker, C. Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Molecular Cell, 2019, 74(3), 421–435.e10. doi: 10.1016/j.molcel.2019.02.029
  4. Yu, C.; Tang, J.; Loredo, A.; Chen, Y.; Jung, S.Y.; Jain, A.; Gordon, A.; Xiao, H. Proximity-Induced Site-Specific Antibody Conjugation. Bioconjugate Chemistry, 2018, 29(11), 3522–3526. doi: 10.1021/acs.bioconjchem.8b00680

Cyanine5.5 maleimide

Cyanine5.5 maleimide,Cyanine5.5 马来酰亚胺是一种硫醇活性染料，能够选择性标记蛋白质中的巯基，它是 Cy5.5® 马来酰亚胺的类似物。

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  • Reactive dyes
  • Dye maleimides
  • Cyanine5.5 maleimide

Cyanine5.5 maleimide

标签：Cyanine5.5, Cy5.5,Maleimides, Microscopy
货号 规格 价格 货期
17080 1 mg 110.00$ 5 days
27080 5 mg 210.00$ in stock
47080 25 mg 410.00$ in stock
57080 50 mg 695.00$ in stock
67080 100 mg 1190.00$ in stock

Cyanine5.5 maleimide is a thiol reactive dye which is capable of selective labeling of sulfhydryl groups in proteins, an analog of Cy5.5® maleimide.

Near infrared emission of Cyanine5.5 makes this dye suitable for bioimaging applications.

Cyanine5.5 can replace Cy5.5® and DyLight 680.

Cyanine5.5 马来酰亚胺是一种硫醇活性染料，能够选择性标记蛋白质中的巯基，它是 Cy5.5® 马来酰亚胺的类似物。

Cyanine5.5 的近红外发射使这种染料适用于生物成像应用。

Cyanine5.5 可以替代 Cy5.5® 和 DyLight 680。

Cy5.5 absorbance and emission spectra

Cyanine5.5 maleimide

Cyanine5.5 maleimide相关产品

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cyanine5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

Cyanine5.5 maleimide Add this product to your cart and
get free express delivery

Cyanine7.5 azide

Long-wavelength NIR fluorescent dye azide for Click chemistry.

用于点击化学的长波长 NIR 荧光染料叠氮化物。

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cy5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 741.36
CAS number: 1593644-50-8
Molecular formula: C46H49ClN4O3
IUPAC name: 1H-​Benz[e]​indolium, 2-​[5-​[3-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​1,​1-​dimethyl-​2H-​benz[e]​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​1,​3-​trimethyl-
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Galstyan, A.; Chiechi, A.; Korman, A.J.; Sun, T.; Isreal, L.L.; Braubach, O.; Patil, R.; Shatalova, E.; Ljubimov, V.A.; Markman, J.; Grodzinski, Z.; Black, K.L.; Penichet, M.L.; Holler, E.; Ljubimov, A.V.; Ding, H.; Ljubimova, J.Y. Nano immunoconjugates crossing blood-brain barrier activate local brain tumor immune system for glioma treatment. bioRxiv, preprint. doi: 10.1101/466508
  2. Özcan, A.; Krajeski, R.; Ioannidi, E.; Lee, B.; Gardner, A.; Makarova, K.S.; Koonin, E.V.; Abudayyeh, O.O.; Gootenberg, J.S. Programmable RNA targeting with the single-protein CRISPR effector Cas7-11. Nature, 2021, 597(7878), 720–725. doi: 10.1038/s41586-021-03886-5
  3. Gardinier, T.C.; Turker, M.Z.; Hinckley, J.A.; Katt, W.P.; DomNwachukwu, N.; Woodruff, F.; Hersh, J.; Wang, J.; Cerione, R.A.; Wiesner, U.B. Controlling Surface Chemical Heterogeneities of Ultrasmall Fluorescent Core–Shell Silica Nanoparticles as Revealed by High-Performance Liquid Chromatography. The Journal of Physical Chemistry C, 2019, 123(37), 23246–23254. doi: 10.1021/acs.jpcc.9b06905
  4. Chen, C.; Corry, B.; Huang, L.; Hildebrandt, N. FRET-modulated multi-hybrid nanoparticles for brightness-equalized single-wavelength barcoding. Journal of the American Chemical Society, 2019, 141(28), 11123–11141. doi: 10.1021/jacs.9b03383

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Cy® is a trademark of Cytiva.

Cyanine5 maleimide

Cyanine5 maleimide,Cyanine5 是 Cy5® 的类似物，Cy5® 是一种常见的荧光团，与显微镜、成像仪和荧光阅读器等各种仪器兼容。

  • Products
  • Reactive dyes
  • Dye maleimides
  • Cyanine5 maleimide

Cyanine5 maleimide

标签：Cyanine5,Cy5, Maleimides, Microscopy
货号 规格 价格 货期
13080 1 mg 110.00$ in stock
23080 5 mg 210.00$ in stock
43080 25 mg 410.00$ in stock
53080 50 mg 695.00$ in stock
63080 100 mg 1190.00$ in stock

Cyanine5 maleimide is a mono-reactive dye which selectively couples with thiol groups (for example, with cysteines in peptides and proteins) to give labeled conjugates.

Cyanine5 is an analog of Cy5®, a common fluorophore which is compatible with various instrumentation like microscopes, imagers, and fluorescence readers.

For the labeling of antibodies and sensitive proteins we recommend to use the water soluble sulfo-Cyanine5 maleimide.

Cy5 马来酰亚胺是一种单反应性染料，可选择性地与硫醇基团（例如，与肽和蛋白质中的半胱氨酸）偶联，形成标记的偶联物。

Cyanine5 是 Cy5® 的类似物，Cy5® 是一种常见的荧光团，与显微镜、成像仪和荧光阅读器等各种仪器兼容。

对于抗体和敏感蛋白的标记，我们建议使用水溶性磺基-Cyanine5 马来酰亚胺。

Cy5 excitation and emission spectra

Cyanine5 maleimide

Cyanine5 maleimide相关产品

FAM hydrazide, 5-isomer

FAM hydrazide is a carbonyl reactive fluorescein derivative. Pure 5-isomer. Can label oxidized proteins, saccharides, and many small molecules with carbonyl groups.

FAM 酰肼是一种羰基反应性荧光素衍生物。 纯5-异构体。 可以用羰基标记氧化的蛋白质、糖类和许多小分子。

Cyanine5 maleimide Add this product to your cart and
get free express delivery

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cyanine5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 605.8
CAS number: 1437872-46-2 (without anion)
Molecular formula: C38H45N4O3
IUPAC name: 3H-​Indolium, 2-​[5-​[1-​[6-​[[2-​(2,​5-​dihydro-​2,​5-​dioxo-​1H-​pyrrol-​1-​yl)​ethyl]​amino]​-​6-​oxohexyl]​-​1,​3-​dihydro-​3,​3-​dimethyl-​2H-​indol-​2-​ylidene]​-​1,​3-​pentadien-​1-​yl]​-​1,​3,​3-​trimethyl-
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (31 uM, 23 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Pishesha, N.; Harmand, T.; Smeding, L.; Ma, W.; Ludwig, L.; Janssen, R.; Islam, A.; Xie, Y.; Fang, T.; McCaul, N.; Pinney, W.; Sugito, H.; Ploegh, H. Single domain antibody-antigen adducts that target Class II MHC induce antigen-specific tolerance. Research Square, preprint. doi: 10.21203/rs.3.rs-192181/v1
  2. Delvaux, N.A.; Mathew, B.; Rice, K.G. Fluorescent Labeling of Plasmid DNA for Gene Delivery: Implications of Dye Hydrophobicity on Labeling Efficiencies and Nanoparticle Size. Analytical Biochemistry, in press. doi: 10.1016/j.ab.2020.113895
  3. Yang, M.; Zhang, L.; Sun, R.; Zhong, W.; Yang, Y.; Chen, C. Streptococcus pyogenes Cas9 displays biased one-dimensional diffusion on dsDNA to search for a target. bioRxiv, preprint. doi: 10.1101/754564
  4. Ast, J.; Arvaniti, A.; Fine, N.H.F.; Nasteska, D.; Ashford, F.B.; Stamataki, Z.M Koszegi, Z.; Bacon, A.; Trapp, S.; Jones, B.J.; Hastoy, B.; Tomas, A.; Reissaus, C.; Linnemann, A.K.; D’Este, E.; Calebiro, D.; Johnsson, K.; Podewin, T.; Broichhagen, J.; Hodson, D.J. LUXendins reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics. bioRxiv, preprint. doi: 10.1101/557132
Cy® is a trademark of GE Healthcare.

Cyanine3 maleimide

Cyanine3 maleimide,硫醇单反应性 Cyanine3 染料。 该试剂可用于将 Cy3 荧光团（Cy3® 的类似物）连接到含有半胱氨酸残基的蛋白质和肽以及其他硫醇化分子（例如含硫醇的寡核苷酸）上。

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  • Cyanine3 maleimide

Cyanine3 maleimide

标签：Cyanine3, Cy3,Maleimides, Microscopy
货号 规格 价格 货期
11080 1 mg 110.00$ in stock
21080 5 mg 210.00$ in stock
41080 25 mg 410.00$ in stock
51080 50 mg 695.00$ in stock
61080 100 mg 1190.00$ in stock

Thiol mono-reactive Cyanine3 dye. This reagent can be used to attach Cyanine3 fluorophore (an analog of Cy3®) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides).

Cystines should be reduced with TCEP (tris-carboxyethylphosphine) or other appropriate reductant prior to the labeling.

Labeling with Cyanine3 maleimide is selective, and efficient.

We recommend using water-soluble Sulfo-Cyanine3 maleimide for the labeling of antibodies and other sensitive proteins.

硫醇单反应性 Cyanine3 染料。 该试剂可用于将 Cyanine3 荧光团（Cy3® 的类似物）连接到含有半胱氨酸残基的蛋白质和肽以及其他硫醇化分子（例如含硫醇的寡核苷酸）上。

标记前应使用 TCEP（三羧乙基膦）或其他合适的还原剂还原胱氨酸。

用 Cyanine3 马来酰亚胺标记具有选择性且有效。

我们建议使用水溶性 Sulfo-Cyanine3 马来酰亚胺标记抗体和其他敏感蛋白。

Cy3 absorbance and emission spectra

Cyanine3 maleimide

Cyanine3 maleimide相关产品

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

Sulfo-Cyanine3 carboxylic acid

Sulfo-Cyanine3 free unactivated monofunctional carboxylic acid, water-soluble dye.

Sulfo-Cyanine3 不含未活化的单官能羧酸，水溶性染料。

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cy3羧酸。

General properties

Appearance: red powder  红色粉末
Molecular weight: 666.56
Molecular formula: C36H43N4O3BF4
Solubility: well soluble in DMSO (0.50 M = 330 g/L), in DMF, dichloromethane, very poorly soluble in water (0.57 mM = 420 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Yang, M.; Zhang, L.; Sun, R.; Zhong, W.; Yang, Y.; Chen, C. Streptococcus pyogenes Cas9 displays biased one-dimensional diffusion on dsDNA to search for a target. bioRxiv, preprint. doi: 10.1101/754564
  2. Budiardjo, S.J.; Deay, J.J.; Calkins, A.L.; Wimalasena, V.K.; Montezano, D.; Biteen, J.S.; Slusky, J.S.G. Colicin E1 Fragments Potentiate Antibiotics by Plugging TolC. bioRxiv, preprint. doi: 10.1101/692251
  3. Mohale, M.; Gundampati, R.K.; Thallapuranam, S.; Heyes, C.D. Site-specific labeling and functional efficiencies of human fibroblast growth Factor-1 with a range of fluorescent dyes in the flexible N-Terminal region and a rigid β-turn region. Analytical Biochemistry, 2022, 640, 114524. doi: 10.1016/j.ab.2021.114524
  4. Bagert, J.D.; Mitchener, M.M.; Patriotis, A.L.; Dul, B.E.; Wojcik, F.; Nacev, B.A.; Feng, L.; Allis, C.D.; Muir, T.W. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nature Chemical Biology, 2021, 17(4), 403–411. doi: 10.1038/s41589-021-00738-1
Cy® is a trademark of GE Healthcare.

BDP TMR maleimide

BDP TMR maleimide,BDP TMR 是用于 TAMRA 通道的明亮硼二吡咯亚甲基荧光团。 这种马来酰亚胺衍生物适合与硫醇基团结合，例如 在蛋白质侧链中。

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  • BDP TMR maleimide

BDP TMR maleimide

标签：Maleimides, Fluorescence polarization, Microscopy, BDP TMR
货号 规格 价格 货期
12480 1 mg 110.00$ in stock
22480 5 mg 210.00$ in stock
42480 25 mg 410.00$ in stock
52480 50 mg 695.00$ in stock
62480 100 mg 1190.00$ in stock

BDP TMR is a bright borondipyrromethene fluorophore for the TAMRA channel. This maleimide derivative is suitable for conjuction with thiol groups as e.g. in protein side chains.

BDP TMR 是用于 TAMRA 通道的明亮硼二吡咯亚甲基荧光团。 这种马来酰亚胺衍生物适合与硫醇基团结合，例如 在蛋白质侧链中。

Absorption and emission spectra of BDP TMR

BDP TMR maleimide

BDP TMR maleimide相关产品

BDP FL hydrazide

Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.

用于 FAM 通道的明亮且光稳定的羰基活性硼二吡咯亚甲基染料。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

BDP TR NHS ester

BDP TR is a borondipyrromethene dye. A bright and photostable fluorophore with high quantum yield.

BDP TR 是一种硼二吡咯亚甲基染料。 具有高量子产率的明亮且光稳定的荧光团。

General properties

Appearance: purple powder  紫色粉末
Mass spec M+ increment: 520.2
Molecular weight: 520.34
CAS number: 2183473-34-7
Molecular formula: C27H27BF2N4O4
IUPAC name: 2-(2-(N-maleimidoethylaminocarbonylethyl))-1,3-dimethyl-5-(4-methoxyphenyl)-4,4-difluoroborondipyrromethene
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16

相关文献：

  1. Gusev, I.D.; Firsov, A.M.; Chertkova, R.V.; Kotova, E.A.; Dolgikh, D.A.; Kirpichnikov, M.P.; Antonenko, Y.N. Study of Interaction of Fluorescent Cytochrome C with Liposomes, Mitochondria, and Mitoplasts by Fluorescence Correlation Spectroscopy. Russian Journal of Bioorganic Chemistry, 2020, 46(6), 1162–1171. doi: 10.1134/S1068162020060084

BDP FL maleimide

BDP FL maleimide,硫醇活性 BDP FL 马来酰亚胺是一种用于蛋白质标记的活性染料，其结构与 BODIPY® FL 马来酰亚胺相同。

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  • BDP FL maleimide

BDP FL maleimide

标签：BDP FL, Maleimides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
11480 1 mg 110.00$ in stock
21480 5 mg 210.00$ in stock
41480 25 mg 410.00$ in stock
51480 50 mg 695.00$ in stock
61480 100 mg 1190.00$ in stock

Thiol reactive BDP FL maleimide is a reactive dye for protein labeling, which has identical structure with BODIPY® FL maleimide.

BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar to fluorescein (FAM). However, this dye exhibits very high photostability. It is non-charged, and has low molecular weight. Its brightness is similar to fluorescein, R110 and xanthene dye derivatives.

This fluorophore is ideal for fluorescent microscopy and many other applications. The fluorophore can substitute fluorescein for almost any application, and it is compatible with any FAM-capable fluorescent instrumentation.

硫醇活性 BDP FL 马来酰亚胺是一种用于蛋白质标记的活性染料，其结构与 BODIPY® FL 马来酰亚胺相同。

BDP FL 是一种硼二吡咯亚甲基染料，其吸收光谱和荧光光谱与荧光素 (FAM) 相似。 然而，这种染料表现出非常高的光稳定性。 它是不带电的，并且具有低分子量。 其亮度类似于荧光素、R110 和呫吨染料衍生物。

这种荧光团是荧光显微镜和许多其他应用的理想选择。 荧光团几乎可以在任何应用中替代荧光素，并且与任何支持 FAM 的荧光仪器兼容。

Absorption and emission spectra of BDP FL

BDP FL maleimide

BDP FL maleimide相关产品

Cyanine5.5 maleimide

Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.

Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

EDC, coupling grade

Water soluble carbodiimide for the coupling of carboxylic acids with amines.

用于羧酸与胺偶联的水溶性碳二亚胺。

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

General properties

Appearance: orange solid  橙色固体
Mass spec M+ increment: 414.1
Molecular weight: 414.21
CAS number: 773859-49-7
Molecular formula: C20H21BF2N4O3
Solubility: Good in organic solvents (DMF, DMSO), limited in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Koch, S.; Seinen, A.-B.; Kamel, M.; Kuckla, D.; Monzel, C.; Kedrov, A.; Driessen, A.J.M. Single-molecule analysis of dynamics and interactions: of the SecYEG translocon. FEBS Journal, 2021, 288(7), 2203–2221. doi: 10.1111/febs.15596
  2. São Pedro, M.N.; Azevedo, A.M.; Aires-Barros, M.R.; Soares, R.R.G. Minimizing the influence of fluorescent tags on IgG partition in PEG-salt aqueous two-phase systems for rapid screening applications. Biotechnology Journal, 2019, 14(8), 1800640. doi: 10.1002/biot.201800640
  3. Doh, J.K.; White, J.D.; Zane, H.K.; Chang, Y.H.; López, C.S.; Enns, C.A.; Beatty, K.E. VIPER is a genetically encoded peptide tag for fluorescence and electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 2018, 115, 12961–12966. doi: 10.1073/pnas.1808626115
  4. Buecheler, J.W.; Winzer, M.; Tonillo, J.; Weber, C.A.; Gieseler, H. Impact of Payload Hydrophobicity on Stability of Antibody-Drug-Conjugates. Molecular Pharmaceutics, 2018, 15(7), 2656–2664. doi: 10.1021/acs.molpharmaceut.8b00177
BODIPY® is a trademark of Life Technologies.

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne,用于 Click Chemistry 的具有炔基的水溶性试剂。 Sulfo-Cyanine5 是一种磺化染料，具有高亲水性和水溶性、极高的消光系数、良好的量子产率和与多种仪器的兼容性。

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  • Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne

标签：sulfo-Cyanine5, Cy5, Alkynes, Microscopy
货号 规格 价格 货期
A33B0 1 mg 110.00$ in stock
B33B0 5 mg 290.00$ in stock
C33B0 10 mg 470.00$ in stock
D33B0 25 mg 690.00$ in stock
E33B0 50 mg 1270.00$ in stock
F33B0 100 mg 1990.00$ in stock

This reagent is recommended for the conjugation with proteins, nanoparticles, and other applications where hydrophilicity is important.

用于 Click Chemistry 的具有炔基的水溶性试剂。 Sulfo-Cyanine5 是一种磺化染料，具有高亲水性和水溶性、极高的消光系数、良好的量子产率和与多种仪器的兼容性。

该试剂推荐用于与蛋白质、纳米颗粒和亲水性很重要的其他应用结合。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 alkyne

Sulfo-Cyanine5 alkyne

Cyanine5 amine

Cyanine5 amine functionalized dye for the coupling with activated esters and epoxides.

用于与活化酯和环氧化物偶联的Cy5 胺官能化染料。

Sulfo-Cyanine7.5 alkyne

Sulfo-Cyanine7.5 is a near infrared fluorophore similar to indocyanine green (ICG), but possessing higher fluorescence quantum yield. The dye is very hydrophilic and water soluble. The reagent is very useful for the labeling of biomolecules for in vivo imaging. This is an alkyne for copper catalyzed Click chemistry.

Sulfo-Cy7.5 是一种类似于吲哚菁绿 (ICG) 的近红外荧光团，但具有更高的荧光量子产率。 该染料是非常亲水和水溶性的。 该试剂对于标记用于体内成像的生物分子非常有用。 这是一种用于铜催化点击化学的炔烃。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

General properties

Appearance: dark blue solid 深蓝色固体
Molecular weight: 717.94
CAS number: 1617572-09-4 (inner salt); 1617497-19-4 (sodium salt)
Molecular formula: C35H40N3KO7S2
Solubility: very high in water, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95+%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a “multiple gear” regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  3. Maklakova, S.Y.; Naumenko, V.A.; Chuprov, A.D.; Mazhuga, M.P.; Zyk, N.V.; Beloglazkina, E.K.; Majouga, A.G. Cellular uptake of N-acetyl-d-galactosamine-, N-acetyl-d-glucosamine- and d-mannose-containing fluorescent glycoconjugates investigated by liver intravital microscopy. Carbohydrate Research, 2020, 489, 107928. doi: 10.1016/j.carres.2020.107928
  4. Zhou, L.; Wu, Y.; Luo, Y.; Li, H.; Meng, X.; Liu, Cl; Xiang, J.; Zhang, P.; Gong, P.; Cai, L. Mitochondria-localized Self-reporting Small Molecule Decorated Theranostic Agents for Cancer-organelle Transporting and Imaging. ACS Applied Bio Materials, 2019, 2(11), 5164–5173. doi: 10.1021/acsabm.9b00811
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine3 alkyne

Sulfo-Cyanine3 alkyne,用于铜催化 Click Chemistry 的水溶性炔烃染料，是 Cy3® 炔烃的类似物。Sulfo-Cyanine3 是一种荧光团，与各种荧光扫描仪、成像仪、显微镜和其他仪器兼容。 它是一种明亮且光稳定的染料，在凝胶中也很容易通过肉眼检测到少量（<1 nmol）。

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  • Sulfo-Cyanine3 alkyne

Sulfo-Cyanine3 alkyne

标签：Alkynes, Microscopy, sulfo-Cyanine3,Cy3.5
货号 规格 价格 货期
A13B0 1 mg 110.00$ in stock 货号 规格 价格 货期
B13B0 5 mg 290.00$ in stock
C13B0 10 mg 470.00$ in stock
D13B0 25 mg 690.00$ in stock
E13B0 50 mg 1270.00$ in stock
F13B0 100 mg 1990.00$ in stock

A water soluble alkyne dye for copper catalyzed Click Chemistry, an analog of Cy3® alkyne.

Sulfo-Cyanine3 is a fluorophore which is compatible with a wide range of fluorescent scanners, imagers, microscopes, and other instrumentation. It is a bright and photostable dye, which is also easily detected in gels by naked eye in low amounts (<1 nmol).

用于铜催化 Click Chemistry 的水溶性炔烃染料，是 Cy3® 炔烃的类似物。

Sulfo-Cyanine3 是一种荧光团，与各种荧光扫描仪、成像仪、显微镜和其他仪器兼容。 它是一种明亮且光稳定的染料，在凝胶中也很容易通过肉眼检测到少量（<1 nmol）。

Absorbance and emission spectra of Sulfo-Cyanine3 dye

Sulfo-Cyanine3 alkyne

Sulfo-Cyanine3 alkyne相关产品

THPTA ligand

THPTA is a water soluble ligand for Cu(I) catalyzed Click chemistry. The ligand stabilizes copper in its Cu(I) oxidation state. Due to high aqueous solubility, reactions with this ligand do not require an organic co-solvent.

THPTA 是一种用于 Cu(I) 催化点击化学的水溶性配体。 配体将铜稳定在其 Cu(I) 氧化态。 由于高水溶性，与该配体的反应不需要有机助溶剂。

Sulfo-Cyanine3 tetrazine

Water soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.

水溶性磺基-Cy3 染料四嗪衍生物，用于用反式环辛烯进行 TCO 连接标记。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5&reg; channel.

用于 Cy5&reg; 的硫醇活性水溶性花青染料 渠道。

General properties

Appearance: dark red powder 暗红色粉末
Mass spec M+ increment: 653.2
Molecular weight: 691.90
CAS number: 2055138-87-7 (inner salt); 2055138-88-8 (sodium salt)
Molecular formula: C33H38KN3O7S2
Solubility: soluble in water (0.57 M = 40 g/L), DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

相关文献:

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a “multiple gear” regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  3. Tugel, U.; Casas, M.G.; Wiltschi, B. Site-Specific Incorporation of Non-canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli. Peptide and Protein Engineering (Springer Protocols Handbooks), 2020, 267–281. doi: 10.1007/978-1-0716-0720-6_14
  4. Sokolova, V.; Nzou, G.; van der Meer, S.B.; Ruks, T.; Heggen, M.; Loza, K.; Hagemann, N.; Murke, F.; Giebel, B.; Hermann, D.M.; Atala, A.J.; Epple, M. Ultrasmall gold nanoparticles (2 nm) can penetrate and enter cell nuclei in an in vitro 3D brain spheroid model. Acta Biomaterialia, 2020, 111, 349–362. doi: 10.1016/j.actbio.2020.04.023
Cy® is a trademark of GE Healthcare.

FAM alkyne, 6-isomer

FAM alkyne, 6-isomer,用于 Click Chemistry 的 FAM（荧光素）荧光团的炔烃衍生物。 纯 (97+%) 单一 6 异构体。荧光素是一种明亮的荧光团，与许多不同的荧光仪器兼容。

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  • FAM alkyne, 6-isomer

FAM alkyne, 6-isomer

标签：FAM (Fluorescein), Alkynes, Fluorescence polarization, Microscopy
货号 规格 价格 货期
A51B0 1 mg 80.00$ in stock
B51B0 5 mg 100.00$ in stock
C51B0 10 mg 150.00$ in stock
D51B0 25 mg 295.00$ in stock
E51B0 50 mg 450.00$ in stock
F51B0 100 mg 780.00$ in stock

Alkyne derivative of FAM (fluorescein) fluorophore for Click Chemistry. Pure (97+%) single 6-isomer.

Fluorescein is a bright fluorophore which is compatible with a number of different fluorescent instruments.

用于 Click Chemistry 的 FAM（荧光素）荧光团的炔烃衍生物。 纯 (97+%) 单一 6 异构体。

荧光素是一种明亮的荧光团，与许多不同的荧光仪器兼容。

FAM absorbance and emission spectra

FAM alkyne, 6-isomer

FAM alkyne, 6-isomer相关产品

Sulfo-Cyanine3 alkyne

A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.

一种用于铜催化点击化学的水溶性染料炔烃。 荧光团 Sulfo-Cyanine3 是一种用于 Cy3® 通道的明亮且光稳定的染料。

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

TAMRA azide, 5-isomer

TAMRA fluorescent dye azide for Click chemistry.

用于点击化学的 TAMRA 荧光染料叠氮化物。

General properties

Appearance: yellow solid 黄色固体
Molecular weight: 413.38
CAS number: 478801-49-9
Molecular formula: C25H15O6N
Solubility: good in aqueous buffers (pH > 8), alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 490
ε, L⋅mol−1⋅cm−1: 80000
Emission maximum, nm: 513
Fluorescence quantum yield: 0.93
CF260: 0.20
CF280: 0.17

相关文献：

  1. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  2. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi: 10.1038/ncomms13088

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer,用于铜催化点击化学的 FAM（荧光素）炔烃，高纯度 (97+%) 5-异构体。 该化合物具有显着的水溶性。

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  • FAM alkyne, 5-isomer

FAM alkyne, 5-isomer

标签：FAM (Fluorescein), Alkynes, Fluorescence polarization, Microscopy
货号 规格 价格 货期
A41B0 1 mg 80.00$ in stock
B41B0 5 mg 100.00$ in stock
C41B0 10 mg 150.00$ in stock
D41B0 25 mg 295.00$ in stock
E41B0 50 mg 450.00$ in stock
F41B0 100 mg 780.00$ in stock

FAM (fluorescein) alkyne for copper-catalyzed Click chemistry, high purity (97+%) 5-isomer. The compound possesses significant aqueous solubility.

用于铜催化点击化学的 FAM（荧光素）炔烃，高纯度 (97+%) 5-异构体。 该化合物具有显着的水溶性。

FAM absorbance and emission spectra

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

用于氨基生物分子标记的水溶性磺基-Cy3 SE 活化酯。

BDP 630/650 maleimide

BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.

BDP 630/650 马来酰亚胺是一种硫醇反应性、基于硼二吡咯亚甲基的染料，经过调整以匹配 Cyanine5 荧光团的远红通道。

Sulfo-Cyanine3 maleimide

Water soluble thiol-reactive derivative of Sulfo-Cyanine3, a Cy3 analog.

Sulfo-Cyanine3 的水溶性硫醇反应性衍生物，一种 Cy3 类似物。

General properties

Appearance: yellow solid 黄色固体
Molecular weight: 413.38
CAS number: 510758-19-7
Molecular formula: C25H15O6N
Solubility: good in aqueous buffers (pH > 8), alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 490
ε, L⋅mol−1⋅cm−1: 80000
Emission maximum, nm: 513
Fluorescence quantum yield: 0.93
CF260: 0.20
CF280: 0.17

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Kamzabek, D.; Le Dé, B.; Coche-Guérente, L.; Miomandre, F.; Dubacheva, G.V. Thermoresponsive Fluorescence Switches Based on Au@pNIPAM Nanoparticles. Langmuir, 2021, 37(37), 10971–10978. doi: 10.1021/acs.langmuir.1c01397
  3. Sokolova, V.; Mekky, G.; van der Meer, S.B.; Seeds, M.C.; Atala, A.J.; Epple, M. Transport of ultrasmall gold nanoparticles (2 nm) across the blood-brain barrier in a six-cell brain spheroid model. Scientific Reports, 2020, 10, 18033. doi: 10.1038/s41598-020-75125-2
  4. Warminski, M.; Kowalska, J.; Jemielity, J. Solid-Phase Synthesis of RNA 5′-Azides and Their Application for Labeling, Ligation, and Cyclization Via Click Chemistry. Current Protocols in Nucleic Acid Chemistry, 2020, 82(1), e112. doi: 10.1002/cpnc.112

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Cyanine5.5 alkyne

Cyanine5.5 alkyne,Cyanine5.5 alkyne,用于点击化学标记的远红/近红外染料炔烃。 Cyanine5.5 是 Cy5.5® 的类似物，Cy5.5® 是一种流行的荧光团，已广泛用于各种应用，包括完整的生物体成像。 该试剂可以在温和的铜催化点击化学条件下与叠氮基结合。

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  • Cyanine5.5 alkyne

Cyanine5.5 alkyne

标签：Cyanine5.5, Cy5.5,Alkynes, Microscopy
货号 规格 价格 货期
A70B0 1 mg 110.00$ in stock
B70B0 5 mg 210.00$ in stock
C70B0 10 mg 310.00$ in stock
D70B0 25 mg 410.00$ in stock
E70B0 50 mg 695.00$ in stock
F70B0 100 mg 1190.00$ in stock

Far red / near infrared dye alkyne for Click Chemistry labeling. Cyanine5.5 is an analog of Cy5.5®, a popular fluorophore which has been widely used for various applications including intact organism imaging. This reagent can be conjugated with azido groups under mild copper catalyzed Click Chemistry conditions.

This reagent is soluble in organic solvents, but mixtures of water with small percent of DMSO can be used for efficient conjugation. Cyanine5.5 alkyne can also be used for the labeling of small molecules with this far red/NIR dye.

用于点击化学标记的远红/近红外染料炔烃。 Cyanine5.5 是 Cy5.5® 的类似物，Cy5.5® 是一种流行的荧光团，已广泛用于各种应用，包括完整的生物体成像。 该试剂可以在温和的铜催化点击化学条件下与叠氮基结合。

该试剂可溶于有机溶剂，但水与少量 DMSO 的混合物可用于有效结合。 Cy5.5 炔烃也可用于用这种远红/NIR 染料标记小分子。

Cyanine5.5 absorbance and emission spectra

Cyanine5.5 alkyne

Cyanine5.5 alkyne相关产品

Cyanine7.5 alkyne

Reactive near infrared (NIR) dye for Click Chemistry containing a terminal alkyne group.

用于 Click Chemistry 的反应性近红外 (NIR) 染料，含有末端炔基。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

sulfo-Cyanine5.5 DBCO

Sulfo-Cyanine5.5 DBCO is a far-red, water-soluble reagent for copper-free reaction with azides.

Sulfo-Cy5.5 DBCO 是一种远红色的水溶性试剂，用于与叠氮化物的无铜反应。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 656.30
CAS number: 1628790-37-3
Molecular formula: C43H46ClN3O
Solubility: good in organic solvents (DMF, DMSO, acetonitrile, DCM, alcohols), practically insoluble in water (5.2 uM, 3.7 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Mickuté, M.; Nainyté, M.; Vasiliauskaité, L.; Plotnikova, A.; Masevičius, V.; Klimašauskas, S.; Vilkaitis, G. Animal Hen1 2′-O-methyltransferases as tools for 3′-terminal functionalization and labelling of single-stranded RNAs. Nucleic Acids Research, 2018, 46(17), e104. doi: 10.1093/nar/gky514
  2. Yuan, H.; Wilks, M.Q.; Fakhri, G.E.; Normandin, M.D.; Kaittanis, C.; Josephson, L. Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials. PLoS One, 2017, 12(2), e0172722. doi: 10.1371/journal.pone.0172722
  3. Duan, Z.; Zhang, Y.; Zhu, H.; Sun, L.; Cai, H.; Li, B.; Gong, Q.; Gu, Z.; Luo, K. Stimuli-Sensitive Biodegradable and Amphiphilic Block Copolymer-Gemcitabine Conjugates Self-assemble Into a Nanoscale Vehicle for Cancer Therapy. ACS Applied Materials & Interfaces, 2017, 9(4), 3474–3486. doi: 10.1021/acsami.6b15232
  4. Shi, Y.; van der Meel, R.; Theek, B.; Oude Blenke, E.; Pieters, E.H.E.; Fens, M.H.A.M.; Ehling, J.; Schiffelers, R.M.; Storm, G.; van Nostrum, C.F.; Lammers, T.; Hennink, W.E. Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π–Π Stacking Stabilized Polymeric Micelles. ACS Nano, 2015, 9(4), 3740–3752. doi: 10.1021/acsnano.5b00929
Cy® is a trademark of GE Healthcare.

Cyanine5 alkyne,Cy5炔烃

Cyanine5 alkyne,Cyanine5 炔烃用于 Click Chemistry，是 Cy5® 炔烃的类似物。 使用该产品，颜色深且光稳定的 Cyanine5 荧光团可以通过与叠氮化物的 Click Chemistry 反应连接到各种分子上。

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  • Cyanine5 alkyne

Cyanine5 alkyne

标签：Cyanine5,Cy5, Alkynes, Microscopy
货号 规格 价格 货期
A30B0 1 mg 110.00$ in stock
B30B0 5 mg 210.00$ in stock
C30B0 10 mg 310.00$ in stock
D30B0 25 mg 410.00$ in stock
E30B0 50 mg 695.00$ in stock
F30B0 100 mg 1190.00$ in stock

Cyanine5 alkyne for Click Chemistry, an analog of Cy5® alkyne. With this product, deeply colored, and photostable Cyanine5 fluorophore can be attached to various molecules via Click Chemistry reaction with azides.

This alkyne is non-water soluble, but it can be dissolved in DMF or DMSO prior to reaction, and added to aqueous reaction mixture. With our labeling protocol, the labeling reaction is very efficient, and high-yielding.

Various substrates bearing azides can be used for the labeling, including azido-labeled biomolecules, polymers, and solid surfaces.

Cyanine5 炔烃用于 Click Chemistry，是 Cy5® 炔烃的类似物。 使用该产品，颜色深且光稳定的 Cyanine5 荧光团可以通过与叠氮化物的 Click Chemistry 反应连接到各种分子上。

这种炔烃不溶于水，但它可以在反应前溶解在 DMF 或 DMSO 中，然后加入到含水反应混合物中。 使用我们的标记方案，标记反应非常有效且产量高。

带有叠氮化物的各种基材可用于标记，包括叠氮标记的生物分子、聚合物和固体表面。

Cyanine5 absorbance and emission spectra

Cyanine5 alkyne

Cyanine5 alkyne

Sulfo-Cyanine3 alkyne

A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.

一种用于铜催化点击化学的水溶性染料炔烃。 荧光团 Sulfo-Cyanine3 是一种用于 Cy3® 通道的明亮且光稳定的染料。

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.

Pico488 是一种染料，用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光，在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。

Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

抗坏血酸用于还原 Cu(II)-TBTA 配合物。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 556.18
CAS number: 1223357-57-0
Molecular formula: C35H42ClN3O
Solubility: good in dichloromethane, DMF, DMSO, alcohols, very poorly soluble in water (200 mg/L = 0.4 mM)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Liu, M.; Apriceno, A.; Sipin, M.; Scarpa, E.; Rodriguez-Arco, L.; Poma, A.; Marchello, G.; Battaglia, G.; Angioletti-Uberti, S. Combinatorial entropy behaviour leads to range selective binding in ligand-receptor interactions. Nature Communications, 2020, 11, 4836. doi: 10.1038/s41467-020-18603-5
  2. Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
  3. Monteiro, P.F.; Gulfam, M.; Monteiro, C.J.; Travanut, A.; Abelha, T.F.; Pearce, A.K.; Jerôme, C.; Grabowska, A.M.; Clarke, P.A.; Collins, H.M.; Heery, D.M.; Gershkovich, P.; Alexander, C. Synthesis of micellar-like terpolymer nanoparticles with reductively-cleavable cross-links and evaluation of efficacy in 2D and 3D models of triple negative breast cancer. Journal of Controlled Release, 2020, 323, 549–564. doi: 10.1016/j.jconrel.2020.04.049
  4. Zivanovic, J.; Kouroussis, E.; Kohl, J.B.; Adhikari, B.; Bursac, B.; Schott-Roux, S.; Petrovic, D.; Miljkovic, J.L.; Thomas-Lopez, D.; Jung, Y.; Miler, M.; Mitchell, S.; Milosevic, V.; Gomes, J.E.; Benhar, M.; Gonzales-Zorn, B.; Ivanovic-Burmazovic, I.; Torregrossa, R:; Mitchell, J.R.; Whiteman, M.; Schwarz, G.; Snyder, S.H.; Paul, B.D.; Carroll, K.S.; Filipovic, M.R. Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration. Cell Metabolism, 2019, 30(6), 1152–1170.e13. doi: 10.1016/j.cmet.2019.10.007
Cy® is a trademark of GE Healthcare.

Cyanine3 alkyne,Cy3炔烃

Cyanine3 alkyne,Cy3 炔烃是一种可用于 Click Chemistry 反应的荧光团。使用该试剂，明亮且光稳定的 Cyanine3 报告基因（Cy3® 的类似物）可以连接到几乎任何带有叠氮基的分子上。这种炔烃是非水溶性的。 然而，当与有机共溶剂（DMSO 或 DMF）一起使用时，这种染料可以有效地附着在水溶性分子上，例如蛋白质或肽

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  • Cyanine3 alkyne

Cyanine3 alkyne

标签：Cyanine3, Cy3,Alkynes, Microscopy
货号 规格 价格 货期
A10B0 1 mg 110.00$ in stock
B10B0 5 mg 210.00$ in stock
C10B0 10 mg 310.00$ in stock
D10B0 25 mg 410.00$ in stock
E10B0 50 mg 695.00$ in stock
F10B0 100 mg 1190.00$ in stock

Cyanine3 alkyne is a fluorophore ready for the use in Click Chemistry reaction.

With this reagent, bright and photostable Cyanine3 reporter, an analog of Cy3®, can be attached to nearly any molecule bearing azide group.

This alkyne is non water-soluble. However, when used with organic co-solvent (DMSO or DMF), this dye can be efficiently attached to water-soluble molecules such as proteins, or peptides.

Cy3 炔烃是一种可用于 Click Chemistry 反应的荧光团。

使用该试剂，明亮且光稳定的 Cyanine3 报告基因（Cy3® 的类似物）可以连接到几乎任何带有叠氮基的分子上。

这种炔烃是非水溶性的。 然而，当与有机共溶剂（DMSO 或 DMF）一起使用时，这种染料可以有效地附着在水溶性分子上，例如蛋白质或肽。

Cyanine3 absorbance and emission spectra

Cyanine3 alkyne

Cyanine3 alkyne相关产品

BDP 558/568 alkyne

BDP 558/568 is a borondipyrromethene dye for Cyanine3 channel. This is a terminal alkyne derivative.

BDP 558/568 是一种用于 Cy3 通道的硼二吡咯亚甲基染料。 这是一种末端炔烃衍生物。

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

水溶性 NIR 染料胺，Cy7 染料的磺化衍生物，用于通过酶促氨基转移进行修饰。

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cyanine3羧酸。

General properties

Appearance: red powder 红色粉末
Molecular weight: 530.14
Molecular formula: C33H40ClN3O
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), , practically insoluble in water (50 mg/L = 80 uM)
Quality control: NMR 1H (95%), HPLC-MS
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Navarro, L.A.; French, D.L.; Zauscher, S. Synthesis of Modular Brush Polymer-Protein Hybrids using Diazotransfer and Copper Click Chemistry. Bioconjugate Chemistry, 2018, 29(8), 2594–2605. doi: 10.1021/acs.bioconjchem.8b00309
  3. Sacoman, J.L.; Dagda, R.Y.; Burnham-Marusich, A.R.; Dagda, R.K.; Berninsone, P.M. Mitochondrial O-GlcNAc transferase (mOGT) regulates mitochondrial structure, function and survival in HeLa cells. Journal of Biological Chemistry, 2017, 292(11), 4499–4518. doi: 10.1074/jbc.M116.726752
  4. Ponomarenko, A.I.; Brylev, V.A.; Sapozhnikova, K.A.; Ustinov, A.V.; Prokhorenko, I.A.; Zatsepin, T.S.; Korshun, V.A. Tetrahedral DNA conjugates from pentaerythritol-based polyazides. Tetrahedron, 2016, 72(19), 2386–2391. doi: 10.1016/j.tet.2016.03.051
Cy2® is a trademark of GE Healthcare.

BDP TMR alkyne,BDP TMR 炔烃

BDP TMR alkyne,BDP TMR 炔烃,BDP TMR 是 TAMRA 通道的荧光团。 由于高量子产率，它比 TAMRA 亮得多。 这种炔烃染料可以通过铜催化的点击化学反应与叠氮化物结合。

  • Products
  • Reactive dyes
  • Dye alkynes
  • BDP TMR alkyne

BDP TMR alkyne

标签：Alkynes, Fluorescence polarization, Microscopy, 显微镜,BDP TMR
货号 规格 价格 货期
A24B0 1 mg 110.00$ in stock
B24B0 5 mg 210.00$ in stock
C24B0 10 mg 310.00$ in stock
D24B0 25 mg 410.00$ in stock
E24B0 50 mg 695.00$ in stock
F24B0 100 mg 1190.00$ 5 days

BDP TMR is a fluorophore for TAMRA channel. Due to high quantum yield, it is much brighter than TAMRA. This alkyne dye can be conjugated with azides by copper-catalyzed Click Chemistry reaction.

BDP TMR 是 TAMRA 通道的荧光团。 由于高量子产率，它比 TAMRA 亮得多。 这种炔烃染料可以通过铜催化的点击化学反应与叠氮化物结合。

Absorption and emission spectra of BODIPY TMR

BDP TMR alkyne

BDP TMR alkyne,BDP TMR 炔烃

FAM alkyne, 6-isomer

Fluorescein dye alkyne for Click Chemistry, pure 6-isomer.

用于 Click Chemistry 的荧光素染料炔烃，纯 6 异构体。

BDP TMR azide

Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.

具有叠氮基的硼二吡咯亚甲基染料。 光谱特性类似于 TAMRA 染料。 由于荧光寿命长，BDP TMR 特别适用于荧光偏振测量。

BDP 650/665 alkyne

BDP 650/665 alkyne is a red emitting BODIPY dye derivative carrying a terminal alkyne group for a copper catalyzed conjugation with azides. Absorption and emission spectra of BDP 650/665 are designed to fit Cy5 channel of various instruments.

BDP 650/665 炔烃是一种发红光的 BODIPY 染料衍生物，带有一个末端炔烃基团，用于铜催化与叠氮化物的共轭。 BDP 650/665 的吸收和发射光谱旨在适应各种仪器的 Cy5 通道。

General properties

Appearance: green-black crystals 绿黑色晶体
Mass spec M+ increment: 435.19
Molecular weight: 435.28
Molecular formula: C24H24BF2N3O2
Solubility: good in chlorinated organic solvents, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16
BODIPY® is a trademark of Life Technologies.

BDP FL alkyne,BDP FL 炔烃

BDP FL alkyne,BDP FL 炔烃,BDP FL 的炔烃衍生物，BODIPY® FL 炔烃的类似物。 BDP FL 是一种硼二吡咯亚甲基染料，一种明亮且光稳定的荧光团，在荧光素 (FAM) 通道中发射。 与 FAM 不同，BDP FL 非常耐光。 它的亮度类似于荧光素。

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  • Reactive dyes
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  • BDP FL alkyne

BDP FL alkyne

标签：BDP FL, Alkynes, Fluorescence polarization, Microscopy,Dye alkynes,炔烃
货号 规格 价格 货期
A14B0 1 mg 110.00$ in stock
B14B0 5 mg 210.00$ in stock
C14B0 10 mg 310.00$ in stock
D14B0 25 mg 410.00$ in stock
E14B0 50 mg 695.00$ in stock
F14B0 100 mg 1190.00$ in stock

Alkyne derivative of BDP FL, an analog of BODIPY® FL alkyne. BDP FL is a borondipyrromethene dye, a bright and photostable fluorophore which emits in fluorescein (FAM) channel. Unlike FAM, BDP FL is very photostable. Its brightness is similar to fluorescein.

This alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.

BDP FL 的炔烃衍生物，BODIPY® FL 炔烃的类似物。 BDP FL 是一种硼二吡咯亚甲基染料，一种明亮且光稳定的荧光团，在荧光素 (FAM) 通道中发射。 与 FAM 不同，BDP FL 非常耐光。 它的亮度类似于荧光素。

这种炔烃可以通过铜催化的点击化学与许多含叠氮化物的分子结合。

BDP FL absorption and emission spectra

BDP FL alkyne

BDP FL alkyne,BDP FL 炔烃相关产品

Cyanine3 alkyne

Cyanine3 alkyne is a fluorescent dye alkyne for Click Chemistry.

Cy3 炔烃是一种用于 Click Chemistry 的荧光染料炔烃。

3-Ethynyl perylene

Alkyne derivative of ultra-bright and photostable perylene fluorophore.

超亮和光稳定苝荧光团的炔烃衍生物。

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cyanine3 荧光染料的叠氮化物衍生物。

General properties

Appearance: orange solid 橙色固体
Mass spec M+ increment: 329.1
Molecular weight: 329.15
CAS number: 302795-84-2, 2006345-30-6
Molecular formula: C17H18BF2N3O
IUPAC name:
Solubility: Good in organic solvents (DMF, DMSO, dichlromethane), limited in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Charoen-Rajapark, P.; Clarke, D.R. Confocal microscopy observations of electrical pre-breakdown of bi-layer elastomer dielectrics. Extreme Mechanics Letters, 2021, 49, 101473. doi: 10.1016/j.eml.2021.101473
  2. Abukar, T.; Rahmani, S.; Thompson, N.K.; Antonescu, C.N.; Wakarchuk, W.W. Development of BODIPY labelled sialic acids as sialyltransferase substrates for direct detection of terminal galactose on N- and O-linked glycans. Carbohydrate Research, 2021, 500, 108249. doi: 10.1016/j.carres.2021.108249
  3. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  4. Du, T.; Buenbrazo, N.; Kell, L.; Rahmani, S.; Sim, L.; Withers, S.G.; DeFrees, S.; Wakarchuk, W.;. A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans. Cell Chemical Biology, 2019, 26(2), 203–212.e5. doi: 10.1016/j.chembiol.2018.10.017
BODIPY® is a trademark of Life Technologies

BDP 630/650 alkyne,BDP 630/650 炔烃

BDP 630/650 alkyne,BDP 630/650 炔烃,BDP 630/650 是一种与 Cy5 通道匹配的红色荧光团。 该染料可用于荧光偏振测定。 它也非常耐光。

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  • BDP 630/650 alkyne

BDP 630/650 alkyne

标签：Fluorescence polarization, Microscopy, BDP 630/650,炔烃
货号 规格 价格 货期
A54B0 1 mg 110.00$ in stock
B54B0 5 mg 210.00$ in stock
C54B0 10 mg 310.00$ in stock
D54B0 25 mg 410.00$ in stock
E54B0 50 mg 695.00$ in stock
F54B0 100 mg 1190.00$ in stock

BDP 630/650 is a red emitting fluorophore matching the Cyanine5 channel. The dye is useful for fluorescence polarization assays. It is also remarkably photostable.

The terminal alkyne group can be conjugated with various azides by copper catalyzed Click chemistry.

BDP 630/650 是一种与 Cy5 通道匹配的红色荧光团。 该染料可用于荧光偏振测定。 它也非常耐光。

末端炔基可以通过铜催化的点击化学与各种叠氮化物缀合。

Absorption and emission spectra of BDP 630/650

BDP 630/650 alkyne

BDP 630/650 alkyne,BDP 630/650 炔烃相关产品

BDP TMR azide

Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.

具有叠氮基的硼二吡咯亚甲基染料。 光谱特性类似于 TAMRA 染料。 由于荧光寿命长，BDP TMR 特别适用于荧光偏振测量。

Sulfo-Cyanine3 tetrazine

Water soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.

水溶性磺基-Cy3 染料四嗪衍生物，用于用反式环辛烯进行 TCO 连接标记。

EdU (5-ethynyl-2′-deoxyuridine)

EdU is a nucleoside which is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by Click chemistry reaction with fluorescent dye azides to reveal cell proliferation.

EdU 是一种核苷，可通过细胞酶掺入复制的 DNA 中。 之后，细胞中所含的 DNA 可以通过与荧光染料叠氮化物的 Click 化学反应进行显色，以揭示细胞增殖情况。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 487.1
Molecular weight: 487.33
CAS number: 2006345-38-4
Molecular formula: C26H20N3BF2O2S
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

AF568 alkyne, 5-isomer,炔烃,Dye alkynes

AF568 alkyne, 5-isomer,炔烃,Dye alkynes,AF568 炔烃衍生物是一种有效的标记工具。 它很容易在 ROX 通道中检测到，在不同的生物样品中具有高信噪比。 此外，AF568 炔烃是水溶性的，对 pH 4 和 pH 10 之间的 pH 变化不敏感。温和的反应条件适用于大多数生物分子、细胞和组织。

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  • AF568 alkyne, 5-isomer

AF568 alkyne, 5-isomer

标签：Alkynes, Microscopy, AF568,炔烃,Dye alkynes
货号 规格 价格 货期
A48B0 1 mg 110.00$ in stock
B48B0 5 mg 290.00$ in stock
C48B0 10 mg 470.00$ in stock
D48B0 25 mg 690.00$ in stock
E48B0 50 mg 1270.00$ in stock
F48B0 100 mg 1990.00$ in stock

The excitation maximum of AF568 lies at 572 nm and its emission maximum is at 598 nm. AF568 has excellent photochemical stability and brightness.

AF568 alkyne derivate is an effective tool for labeling purposes. It is easily detected in the ROX channel with a high signal-to-noise ratio in different biological samples. Besides, AF568 alkyne is water soluble and insensitive to pH changes between pH 4 and pH 10. Mild reaction conditions are suitable for most biomolecules, cells, and tissues.

Bioconjugation with AF568 alkyne presents a powerful technique for the production of fluorescently labeled biomolecules. AF568 alkyne is recommended for visualization procedures, including fluorescence microscopy, flow cytometry, and other applications where label brightness and photostability are required.

AF568 的最大激发位于 572 nm，其发射最大位于 598 nm。 AF568 具有优异的光化学稳定性和亮度。

AF568 炔烃衍生物是一种有效的标记工具。 它很容易在 ROX 通道中检测到，在不同的生物样品中具有高信噪比。 此外，AF568 炔烃是水溶性的，对 pH 4 和 pH 10 之间的 pH 变化不敏感。温和的反应条件适用于大多数生物分子、细胞和组织。

与 AF568 炔烃的生物共轭为生产荧光标记的生物分子提供了一种强大的技术。 AF568 炔烃推荐用于可视化程序，包括荧光显微镜、流式细胞术和其他需要标签亮度和光稳定性的应用。

Absorption and emission spectra of AF568

AF568 alkyne, 5-isomer

AF568 alkyne, 5-isomer,炔烃,Dye alkynes相关产品

AF430 tetrazine

Tetrazine derivative of AF430 fluorescent dye suitable for in vitro cell labeling.

AF430 荧光染料的四嗪衍生物，适用于体外细胞标记。

AF568 NHS ester

AF568 derivative for labeling proteins and other high- and low-molecular weight ligands with free amines.

AF568 衍生物，用于用游离胺标记蛋白质和其他高分子量和低分子量配体。

AF488 azide

AF488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.

AF488 azide 是一种在绿色光谱范围内发射的荧光团。 它在铜催化的环加成反应中与炔烃反应。

General properties

Appearance: violet powder 紫罗兰粉
Mass spec M+ increment: 731.2
Molecular weight: 807.97
Molecular formula: C36H31N3K2O10S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 572
ε, L⋅mol−1⋅cm−1: 94238
Emission maximum, nm: 598
Fluorescence quantum yield: 0.912
CF260: 0.4
CF280: 0.32

Sulfo-Cyanine5 azide,Cy5 叠氮化物

Sulfo-Cyanine5 azide,Cy5 叠氮化物,用于点击化学的水溶性 Cyanine5 染料叠氮化物。 具有红色荧光的明亮且光稳定的染料。 该试剂具有高水溶性。 由于高溶解度和亲水性，该染料可用于在天然、纯水性条件下标记生物分子。

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  • Sulfo-Cyanine5 azide

Sulfo-Cyanine5 azide

标签：sulfo-Cyanine5,Cy5, Azides, Microscopy
货号 规格 价格 货期
A3330 1 mg 110.00$ in stock
B3330 5 mg 290.00$ in stock
C3330 10 mg 470.00$ in stock
D3330 25 mg 690.00$ in stock
E3330 50 mg 1270.00$ in stock
F3330 100 mg 1990.00$ in stock

Water-soluble Cyanine5 dye azide for Click chemistry. Bright and photostable dye with red fluorescence. The reagent has high water solubility. Due to high solubility and hydrophilicity, the dye can be used for labeling biomolecules in native, purely aqueous conditions.

This reagent, as opposed to competing products, is supplied as an alkaline metal salt and not triethylammonium salt. Therefore, it is a powder which is easy to handle and dispense.

Sulfo-Cyanine5 is an analog of Cy5®, a very popular fluorophore, therefore this reagent is compatible to a wide range of standard fluorescent instrumentation such as imagers, plate readers, and microscopes.

用于点击化学的水溶性 Cyanine5 染料叠氮化物。 具有红色荧光的明亮且光稳定的染料。 该试剂具有高水溶性。 由于高溶解度和亲水性，该染料可用于在天然、纯水性条件下标记生物分子。

与竞争产品不同，该试剂以碱金属盐而非三乙基铵盐的形式提供。 因此，它是一种易于处理和分配的粉末。

Sulfo-Cyanine5 是 Cy5® 的类似物，Cy5® 是一种非常流行的荧光团，因此该试剂与各种标准荧光仪器兼容，例如成像仪、读板机和显微镜。

Sulfo-Cyanine5 absorbance and emission spectra

Sulfo-Cyanine5 azide

Sulfo-Cyanine5 azide,Cy5 叠氮化物相关产品

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

Sulfo-Cyanine7 maleimide

Water soluble near infrared dye maleimide for the labeling of proteins and peptides.

水溶性近红外染料马来酰亚胺，用于标记蛋白质和肽。

Alkyne Phosphoramidite, 5′-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.

用于合成寡核苷酸的炔亚磷酰胺，可用于点击化学。

General properties

Appearance: dark blue crystals 深蓝色晶体
Molecular weight: 762.98
Molecular formula: C35H43N6KO7S2
Solubility: very high in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关文献：

  1. Rueda-Alaña, E.; García-Moreno, F. Time in Neurogenesis: Conservation of the Developmental Formation of the Cerebellar Circuitry. Brain, Behavior and Evolution. doi: 10.1159/000519068
  2. Singh, A.; Jothiprakasam, T.; Raghavan, J.V.; Jhunjhunwala, S. Sterile Inflammation Alters Neutrophil Kinetics in Mice. bioRxiv, preprint. doi: 10.1101/2021.02.12.430891
  3. Toyonaga, T.; Keith, B.P.; Barrow, J.B.; Schaner, M.S.; Wolber, E.A.; Beasley, C.; Huling, J.; Wang, Y.; Allbritton, N.L.; Chaumont, N.; Sadiq, T.S.; Koruda, M.j.; Rahbar, R.; Furey, T.S.; Sethupathy, P.; Sheikh, S.Z. Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier integrity and is associated with a poor clinical outcome in Crohn’s disease. bioRxiv, preprint. doi: 10.1101/2020.02.21.960070
  4. Hinman, S.; Wang, Y.; Allbritton, N. Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models. ChemRxiv, preprint. doi: 10.26434/chemrxiv.9759605.v1
Cy® is a trademark of GE Healthcare.

Sulfo-Cyanine3 azide

Sulfo-Cyanine3 azide,Sulfo-Cyanine3 azide 是一种用于 Click Chemistry 的水溶性染料叠氮化物。 染料的吸光度和发射与 Cy3® 荧光团相同。

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  • Sulfo-Cyanine3 azide

Sulfo-Cyanine3 azide

标签：Azides, Microscopy, sulfo-Cyanine3,Cy3
货号 规格 价格 货期
A1330 1 mg 110.00$ in stock
B1330 5 mg 290.00$ in stock
C1330 10 mg 470.00$ in stock
D1330 25 mg 690.00$ in stock
E1330 50 mg 1270.00$ in stock
F1330 100 mg 1990.00$ in stock

Sulfo-Cyanine3 azide is a water-soluble dye azide for Click Chemistry. Absorbance and emission of the dye are identical to Cy3® fluorophore.

Brightness and photostability of fluorophore, together with high water solubility, makes this reagent an ideal choice for Click chemistry labeling of various molecules in aqueous phase.

Click reaction can be carried out in pure water without need to use organic co-solvent. The reagent is designed for the labeling of sensitive molecules such as proteins, and even intact biological objects.

Sulfo-Cyanine3 azide 是一种用于 Click Chemistry 的水溶性染料叠氮化物。 染料的吸光度和发射与 Cy3® 荧光团相同。

荧光团的亮度和光稳定性以及高水溶性使该试剂成为水相中各种分子的点击化学标记的理想选择。

点击反应可在纯水中进行，无需使用有机助溶剂。 该试剂设计用于标记蛋白质等敏感分子，甚至是完整的生物对象。

Sulfo-Cyanine3 absorbance and emission spectra

Sulfo-Cyanine3 azide

Sulfo-Cyanine3 azide相关产品

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

Pico488 dsDNA quantification reagent, 200x solution in DMSO

Pico488 is a dye for precise fluorescence based quantification of dsDNA in the presence of RNA, ssDNA, and other impurities. The dye exhibits bright fluorescence in the fluorescein channel, which provides a linear response to DNA concentration within the range of low pg/mL to high ng/mL.

Pico488 是一种染料，用于在存在 RNA、ssDNA 和其他杂质的情况下对 dsDNA 进行基于荧光的精确定量。 该染料在荧光素通道中显示出明亮的荧光，在低 pg/mL 至高 ng/mL 范围内对 DNA 浓度提供线性响应。

Cyanine3 maleimide

Cyanine3 maleimide is a thiol mono reactive dye.

Cy3 马来酰亚胺是一种硫醇单活性染料。

General properties

Appearance: dark red crystals 暗红色晶体
Molecular weight: 736.94
CAS number: 2055138-89-9 (sodium salt), 1658416-54-6
Molecular formula: C33H41N6KO7S2
Solubility: soluble in water (0.62 M = 46 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

相关文献：

  1. Wells, C.I.; Al-Ali, H.; Andrews, D.M.; Asquith, C.R.M.; Axtman, A.D.; Chung, M.; Dikic, I.; Ebner, D.; Elkins, J.M.; Ettmayer, P.; Fischer, C.; Frederiksen, M.; Gray, N.S.; Hatch, S.; Knapp, S.; Lee, S.; Lücking, U.; Michaelides, M.; Mills, C.E.; Müller, S.; Owen, D.; Picado, A.; Ramadan, K.; Saikatendu, K.S.; Schröder, M.; Stolz, A.; Tellechea, M.; Treiber, D.K.; Turunen, B.J.; Vilar, S.; Wang, J.; Zuercher, W.J.; Willson, T.M.; Drewry, D.H. The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification. bioRxiv, preprint. doi: 10.1101/2019.12.22.886523
  2. Li, D.; Taylor, D.H.; van Wolfswinkel, J.C. PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation. Cell Reports, 2021, 37(1), 109776. doi: 10.1016/j.celrep.2021.109776
  3. Wang, J.; Li, T.; Wang, J.-L.; Xu, Z.; Meng, W.; Wu, Q.-F. Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Reports, 2020, 33(11), 108495. doi: 10.1016/j.celrep.2020.108495
  4. Zahnreich, S.; Weber, B.; Rösch, G.; Schindler, D.; Schmidberger, H. Compromised repair of radiation-induced DNA double-strand breaks in Fanconi anemia fibroblasts in G2. DNA Repair, 2020, 96, 102992. doi: 10.1016/j.dnarep.2020.102992
Cy® is a trademark of GE Healthcare.

ROX azide, 5- isomer,ROX 叠氮化物

ROX azide, 5- isomer,ROX 叠氮化物,ROX (rhodamine-X) 叠氮化物、固体材料和 10 mM DMSO 溶液，Click Chemistry 的标记试剂。 ROX 是一种发红光的罗丹明染料，具有高亮度和荧光量子产率。

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  • ROX azide, 5- isomer

ROX azide, 5- isomer

标签：ROX (Rhodamine X Rhodamine 101), Azides, Microscopy
货号 规格 价格 货期
11230 100 uL, 10 mM/DMSO 110.00$ in stock
31230 500 uL, 10 mM/DMSO 210.00$ in stock
41230 1 mL, 10 mM/DMSO 410.00$ in stock
A1230 1 mg 110.00$ in stock
B1230 5 mg 210.00$ in stock
C1230 10 mg 310.00$ in stock
D1230 25 mg 410.00$ in stock
E1230 50 mg 695.00$ in stock

ROX (rhodamine-X) azide, solid material, and 10 mM solution in DMSO, labeling reagent for Click Chemistry. ROX is a red-emitting rhodamine dye possessing high brightness and fluorescence quantum yield.

ROX (rhodamine-X) 叠氮化物、固体材料和 10 mM DMSO 溶液，Click Chemistry 的标记试剂。 ROX 是一种发红光的罗丹明染料，具有高亮度和荧光量子产率。

Pure 5-isomer.

Absorption and emission spectra of ROX dye

ROX azide, 5- isomer

ROX azide, 5- isomer,ROX 叠氮化物相关产品

Cyanine7 azide

Near-infrared fluorescent dye for Click Chemistry.

用于点击化学的近红外荧光染料。

ROX azide, 5- isomer Add this product to your cart and
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ROX NHS ester, 5-isomer

Activated NHS ester of ROX (rhodamine X or rhodamine 101), pure 5-isomer, for the labeling of amine groups of biomolecules.

ROX 的活化 NHS 酯（罗丹明 X 或罗丹明 101），纯 5-异构体，用于标记生物分子的胺基。

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃，5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

General properties

Appearance: dark crimson powder / red solution
Molecular weight: 616.71
CAS number: 2628213-67-0
Molecular formula: C36H36N6O4
Solubility: good in polar organic solvents (DMF, DMSO, alcohols), low in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 570
ε, L⋅mol−1⋅cm−1: 93000
Emission maximum, nm: 591
Fluorescence quantum yield: 1.0

相关文献：

  1. Feltes, M.; Moores, S.; Gale, S.E.; Krishnan, K.; Mydock-McGrane, L.; Covey, D.F.; Ory, D.S.; Schaffer, J.E. Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking. Journal of Lipid Research, 2019, 60(3), 707–716. doi: 10.1194/jlr.D091470
  2. Verardi, R.; Kim, J.-S.; Ghirlando, R.; Banerjee, A. Structural Basis for Substrate Recognition by the Ankyrin Repeat Domain of Human DHHC17 Palmitoyltransferase. Structure, 2017, 25(9), 1337–1347. doi: 10.1016/j.str.2017.06.018
  3. Bak, D.W.; Pizzagalli, M.D.; Weerapana, E. Identifying Functional Cysteine Residues in the Mitochondria. ACS Chemical Biology, 2017, 12(4), 947–957. doi: 10.1021/acschembio.6b01074
  4. Nåbo, L.J.; Madsen, C.S.; Jensen, K.J.; Kongsted, J.; Astakhova, K. Ultramild Protein-Mediated Click Chemistry Creates Efficient Oligonucleotide Probes for Targeting and Detecting Nucleic Acids. ChemBioChem, 2015, 16(8), 1163–1167. doi: 10.1002/cbic.201500145

FAM azide, 6-isomer,FAM 叠氮化物,6-isomer

FAM azide, 6-isomer,FAM 叠氮化物,6-isomer,FAM（荧光素）叠氮化物。 固体和 10 mM DMSO 溶液，用于点击化学的标记试剂。

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  • FAM azide, 6-isomer

FAM azide, 6-isomer

标签：FAM (Fluorescein), Azides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
15130 100 uL, 10 mM/DMSO 80.00$ in stock
35130 500 uL, 10 mM/DMSO 100.00$ in stock
45130 1 mL, 10 mM/DMSO 150.00$ in stock
A5130 1 mg 80.00$ in stock
B5130 5 mg 100.00$ in stock
C5130 10 mg 150.00$ in stock
D5130 25 mg 295.00$ 5 days
E5130 50 mg 450.00$ in stock
F5130 100 mg 780.00$ in stock

FAM (fluorescein) azide. solid and 10 mM solution in DMSO, labeling reagent for Click chemistry.

Pure 6-isomer.

Can replace DyLight 488.

FAM（荧光素）叠氮化物。 固体和 10 mM DMSO 溶液，用于点击化学的标记试剂。

纯 6 异构体。

可替代 DyLight 488。

FAM azide, 6-isomer,FAM 叠氮化物,6-isomer相关产品

Alkyne NHS ester (hexynoic acid NHS ester)

Alkyne NHS ester for the labeling of biomolecules with alkyne group for Copper catalyzed Click chemistry.

炔烃 NHS 酯，用于标记具有炔烃基团的生物分子，用于铜催化的点击化学。

ROX reference dye for qPCR

ROX is a passive reference dye for qPCR amplification. The dye can be used to normalize fluorescence intensity of reporter dye in qPCR.

ROX 是用于 qPCR 扩增的被动参考染料。 该染料可用于标准化 qPCR 中报告染料的荧光强度。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

General properties

Appearance: yellowish crystals 淡黄色晶体
Molecular weight: 458.42
CAS number: 1386385-76-7
Molecular formula: C24H18N4O6
Solubility: soluble in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献：

  1. Haider, N.; Dutt, P.; van de Kooij, B.; Yaffe, M.B.; Stambolic, V. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. bioRxiv, preprint. doi: 10.1101/516971
  2. Lee, R.; Erstling, J.A.; Hinckley, J.A.; Chapman, D.V.; Wiesner, U.B. Addressing Particle Compositional Heterogeneities in Super-Resolution-Enhanced Live-Cell Ratiometric pH Sensing with Ultrasmall Fluorescent Core–Shell Aluminosilicate Nanoparticles. Advanced Functional Materials, 2021, 31(45), 2106144. doi: 10.1002/adfm.202106144
  3. Ramey-Ward, A.N.; Su, H.; Salaita, K. Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis. ACS Applied Materials & Interfaces, 2020, 12(32), 35903–35917. doi: 10.1021/acsami.0c08871
  4. Reed, S.A.; Brzovic, D.A.; Takasaki, S.S.; Boyko, K.V.; Antos, J.M. Efficient Sortase-Mediated Ligation Using a Common C-Terminal Fusion Tag. Bioconjugate Chemistry, 2020, 31(5), 1463–1473. doi: 10.1021/acs.bioconjchem.0c00156

FAM azide, 5-isomer,FAM 叠氮化物，5-isomer

FAM azide, 5-isomer,FAM 叠氮化物，5-isomer,FAM 叠氮化物既可作为固体化合物使用，也可作为 10 mM DMSO 溶液提供，可用于我们推荐的标记方案。 本品为纯5-异构体。 FAM 是 DyLight 488 的替代品。

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  • FAM azide, 5-isomer

FAM azide, 5-isomer

标签：FAM (Fluorescein), Azides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
14130 100 uL, 10 mM/DMSO 80.00$ in stock
34130 500 uL, 10 mM/DMSO 100.00$ in stock
44130 1 mL, 10 mM/DMSO 150.00$ in stock
A4130 1 mg 80.00$ in stock
B4130 5 mg 100.00$ in stock
C4130 10 mg 150.00$ in stock
D4130 25 mg 295.00$ in stock
E4130 50 mg 450.00$ in stock
F4130 100 mg 780.00$ in stock

FAM azide for Click chemistry labeling. FAM remains one of the most popular fluorescent labels for various applications. Most instruments capable of fluorescence detection, ranging from plate readers to fluorescence microscopes, are able to work in FAM channel.

With versatility of Click chemistry and this reagent, it is possible to attach this popular fluorophore to nearly any alkyne bearing molecule.

FAM azide is available both as solid compound, and as 10 mM solution in DMSO ready to use in our recommended labeling protocol. This product is a pure 5-isomer. FAM is a replacement for DyLight 488.

用于点击化学标记的 FAM 叠氮化物。 FAM 仍然是各种应用中最受欢迎的荧光标记之一。 大多数能够进行荧光检测的仪器，从读板器到荧光显微镜，都能够在 FAM 通道中工作。

借助 Click 化学和该试剂的多功能性，可以将这种流行的荧光团连接到几乎任何带有炔烃的分子上。

FAM 叠氮化物既可作为固体化合物使用，也可作为 10 mM DMSO 溶液提供，可用于我们推荐的标记方案。 本品为纯5-异构体。 FAM 是 DyLight 488 的替代品。

FAM azide, 5-isomer,FAM 叠氮化物，5-isomer相关产品

BDP TMR NHS ester

Amine reactive NHS ester of BDP TMR, bright borondipyrromethene dye for TAMRA channel especially suitable for fluorescence polarization assays.

BDP TMR 的胺活性 NHS 酯，用于 TAMRA 通道的明亮硼二吡咯亚甲基染料，特别适用于荧光偏振测定。

HEX azide, 6-isomer

Azide of green-yellow emitting HEX dye is used for conjugation with oligonucleotides via [3+2]-dipolar cycloaddition.

绿黄色发射 HEX 染料的叠氮化物用于通过 [3+2]-偶极环加成与寡核苷酸缀合。

BDP TR azide

BDP TR is a red emitting fluorophore for ROX channel. This is an azide for copper catalyzed and copper free Click chemistry conjugation.

BDP TR 是一种用于 ROX 通道的红色发射荧光团。 这是一种用于铜催化和无铜点击化学偶联的叠氮化物。

General properties

Appearance: yellowish crystals 淡黄色晶体
Molecular weight: 458.42
CAS number: 510758-23-3
Molecular formula: C24H18N4O6
Solubility: soluble in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献：

  1. Haider, N.; Dutt, P.; van de Kooij, B.; Yaffe, M.B.; Stambolic, V. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. bioRxiv, preprint. doi: 10.1101/516971
  2. Gueiderikh, A.; Maczkowiak-Chartois, F.; Rouvet, G.; Souquère-Besse, S.; Apcher, S.; Diaz, J.-J.; Rosselli, F. Fanconi anemia A protein participates in nucleolar homeostasis maintenance and ribosome biogenesis. Science Advances, 2021, 7(1), eabb5414. doi: 10.1126/sciadv.abb5414
  3. Ramey-Ward, A.N.; Su, H.; Salaita, K. Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis. ACS Applied Materials & Interfaces, 2020, 12(32), 35903–35917. doi: 10.1021/acsami.0c08871
  4. Kim, D.; Singh, N.; Waldemer-Streyer, R.J.; Yoon, M.-S.; Chen, J. Muscle-derived TRAIL negatively regulates myogenic differentiation. Experimental Cell Research, 2020, 394(1), 112165. doi: 10.1016/j.yexcr.2020.112165

Cy5.5 azide,Cy5.5 叠氮化物

Cy5.5 azide,Cy5.5 叠氮化物,这种 Cy5.5 标记试剂是一种用于 Click Chemistry 的染料叠氮化物，可作为 10 mM DMSO 溶液或固体形式提供。 该染料具有远红/近红外发射，可用于近红外活体生物成像。 Cy5.5 可以替代 Cy5.5® 和 DyLight 680。

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  • Cyanine5.5 azide

Cyanine5.5 azide

标签：Cyanine5.5,Cy5.5, Azides, Microscopy
货号 规格 价格 货期
14030 100 uL, 10 mM/DMSO 110.00$ in stock
34030 500 uL, 10 mM/DMSO 210.00$ in stock
44030 1 mL, 10 mM/DMSO 410.00$ in stock
A4030 1 mg 110.00$ in stock
B4030 5 mg 210.00$ in stock
C4030 10 mg 310.00$ in stock
D4030 25 mg 410.00$ in stock
E4030 50 mg 695.00$ in stock

This Cyanine5.5 labeling reagent is a dye azide for Click Chemistry, available as 10 mM solution in DMSO, or in solid form. The dye possesses far red / near infrared emission, which allows to use it for NIR live organism imaging. Cyanine5.5 can replace Cy5.5® and DyLight 680.

这种 Cy5.5 标记试剂是一种用于 Click Chemistry 的染料叠氮化物，可作为 10 mM DMSO 溶液或固体形式提供。 该染料具有远红/近红外发射，可用于近红外活体生物成像。 Cy5.5 可以替代 Cy5.5® 和 DyLight 680。

Cy5.5 absorbance and emission spectra

Cyanine5.5 azide

Cy5.5 azide,Cy5.5 叠氮化物相关产品

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.

Cy5.5 未活化的游离酸性花青染料。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cyanine7的胺活性NHS酯。

Cyanine7 hydrazide

Carbonyl reactive NIR fluorophore for the labeling of aldehydes, ketones, including glycoproteins subjected to periodate oxidation.

羰基反应性 NIR 荧光团，用于标记醛、酮，包括经过高碘酸盐氧化的糖蛋白。

General properties

Appearance: dark blue powder / solution 深蓝色粉末/溶液
Molecular weight: 701.34
Molecular formula: C43H49ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), practically insoluble in water (1.6 uM, 1.2 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Binkhathlan, Z.; Ali, R.; Qamar, W.; Al-Lawati, H.; Lavasanifar, A. Pharmacokinetic and Tissue Distribution of Orally Administered Cyclosporine A-Loaded poly(ethylene oxide)-block-Poly(ε-caprolactone) Micelles versus Sandimmune® in Rats. Pharmaceutical Research, 2021, 38(1), 51–65. doi: 10.1007/s11095-021-02990-5
  2. Bobrin, V.A.; Lin, Y.; He, J.; Qi, Y.; Gu, W.; Monteiro, M.J. Therapeutic Delivery of Polymeric Tadpole Nanostructures with High Selectivity to Triple Negative Breast Cancer Cells. Biomacromolecules, 2020, 21(11), 4457–4468. doi: 10.1021/acs.biomac.0c00302
  3. Yuan, M.; Chen, X.; Sun, Y.; Jiang, L.; Xia, Z:; Ye, K.; Jiang, H.; Yang, B.; Ying, M.; Cao, J.; He, Q. ZDHHC12-mediated claudin-3 S-palmitoylation determines ovarian cancer progression. Acta Pharmaceutica Sinica B, 2020, 10(8), 1426–1439. doi: 10.1016/j.apsb.2020.03.008
  4. Hellyer, S.D.; Aggarwal, S.; Chen, A.N.; Leach, K.; Lapinsky, D.J.; Gregory, K.J. Development of Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 2 Based on Two Positive Allosteric Modulator Chemotypes. ACS Chemical Neuroscience, 2020, 11(11), 1597–1609. doi: 10.1021/acschemneuro.0c00009
Cy® is a trademark of Cytiva.

Cy5 azide,Cy5 叠氮化物

Cy5 azide,Cy5 叠氮化物,用于 Click Chemistry 的 Cy5 叠氮化物标记试剂，以 10 mM DMSO 溶液和固体形式提供。这种叠氮化物可溶于有机溶剂（例如 DMSO、DMF），因此标记反应应使用少量有机助溶剂进行。 这种叠氮化物可用于在水与有机溶剂的混合物中标记炔烃修饰的生物分子。 DMSO 中的溶液可用于生物偶联。 该试剂的水溶性磺化版本也可用。

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  • Reactive dyes
  • Dye azides
  • Cyanine5 azide

Cyanine5 azide

标签：Cyanine5, Cy5,Azides, Microscopy
货号 规格 价格 货期
13030 100 uL, 10 mM/DMSO 110.00$ in stock
33030 500 uL, 10 mM/DMSO 210.00$ in stock
43030 1 mL, 10 mM/DMSO 410.00$ in stock
A3030 1 mg 110.00$ in stock
B3030 5 mg 210.00$ in stock
C3030 10 mg 310.00$ in stock
D3030 25 mg 410.00$ in stock
E3030 50 mg 695.00$ in stock
F3030 100 mg 1190.00$ in stock

Cyanine5 azide labeling reagent for Click Chemistry, available as 10 mM solution in DMSO, and in solid form.

This azide is soluble in organic solvents (e.g. DMSO, DMF), therefore the labeling reaction should be carried out with a small amount of an organic co-solvent. This azide can be used for the labeling of alkyne-modified biomolecules in mixtures of water with organic solvents. The solution in DMSO is ready for use in bioconjugation. A water-soluble sulfonated version of this reagent is also available.

Cyanine5 is an analog of Cy5®, one of the most commonly used fluorophores which is compatible with various instruments. Cyanine5 can also be used as a replacement for DyLight® 649.

用于 Click Chemistry 的 Cyanine5 叠氮化物标记试剂，以 10 mM DMSO 溶液和固体形式提供。

这种叠氮化物可溶于有机溶剂（例如 DMSO、DMF），因此标记反应应使用少量有机助溶剂进行。 这种叠氮化物可用于在水与有机溶剂的混合物中标记炔烃修饰的生物分子。 DMSO 中的溶液可用于生物偶联。 该试剂的水溶性磺化版本也可用。

Cyanine5 是 Cy5® 的类似物，Cy5® 是最常用的荧光团之一，可与各种仪器兼容。 Cyanine5 也可用作 DyLight® 649 的替代品。

Cyanine5 absorbance and emission spectra

Cyanine5 azide

Cy5 azide,Cy5 叠氮化物相关产品

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.

BDP 581/591 是一种硼二吡咯亚甲基荧光团，可用于荧光偏振测定、显微镜检查和两个光子实验。 该炔烃是铜催化点击化学的衍生物。

Ascorbic acid

Ascorbic acid for the reduction of Cu(II)-TBTA complex.

抗坏血酸用于还原 Cu(II)-TBTA 配合物。

General properties

Appearance: dark blue powder / solution
Molecular weight: 601.22
CAS number: 1267539-32-1 (chloride)
Molecular formula: C35H45ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), very poorly soluble in water (0.63 mM, 110 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
  2. Boersma, S.; Rabouw, H.H.; Bruurs, L.J.M.; Pavlovič, T.; van Vliet, A.L.W.; Beumer, J.; Clevers, H.; van Kuppeveld, F.J.M.; Tanenbaum, M.E. Translation and Replication Dynamics of Single RNA Viruses. Cell, 2020, 183(7), 1930–1945.e23. doi: 10.1016/j.cell.2020.10.019
  3. Kim, S.M.; Park, J.; Kim, M.S.; Song, H.; Jo, A.; Park, H.; Kim, T.S.; Choi, S.H.; Park, S.B. Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR. ACS Infectious Diseases, 2020, 6(11), 3076–3082. doi: 10.1021/acsinfecdis.0c00587
  4. von Döhren, J.; Kuhl, S. A simple method for long-term vital-staining of ciliated epidermal cells in aquatic larvae. Journal of Biological Methods, 2020, 7(2), e132. doi: 10.14440/jbm.2020.320
Cy® is a trademark of Cytiva.

Cy3 azide,Cy3 叠氮化物

Cy3 azide,Cy3 叠氮化物,用于 Click Chemistry 的 Cyanine3 染料叠氮化物，是 Cy3® 叠氮化物的类似物。 Cy3® 是使用最广泛的荧光团之一，可以通过各种荧光计、成像仪和显微镜进行检测。 由于固有的高消光系数，Cyanine3 也很容易通过肉眼在凝胶上和溶液中检测到。 这是一种非磺化染料，需要有机助溶剂（DMF、DMSO 或其他）在水中进行有效标记。 该试剂的水溶性版本也可用。

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  • Dye azides
  • Cyanine3 azide

Cyanine3 azide

标签：Cyanine3, Cy3,Azides, Microscopy
货号 规格 价格 货期
11030 100 uL, 10 mM/DMSO 110.00$ in stock
31030 500 uL, 10 mM/DMSO 210.00$ in stock
41030 1 mL, 10 mM/DMSO 410.00$ in stock
A1030 1 mg 110.00$ in stock
B1030 5 mg 210.00$ in stock
C1030 10 mg 310.00$ in stock
D1030 25 mg 410.00$ in stock
E1030 50 mg 695.00$ in stock
F1030 100 mg 1190.00$ in stock

Cyanine3 dye azide for Click Chemistry, an analog of Cy3® azide. Cy3® is one of the most broadly used fluorophores which can be detected by various fluorometers, imagers, and microscopes. Due to inherently high extinction coefficient, Cyanine3 is also easily detected by naked eye on gels, and in solution. This is non-sulfonated dye which requires organic co-solvent (DMF, DMSO, or other) for efficient labeling in water. Water-soluble version of this reagent is also available.

Product is available both as solid compound, and as 10 mM solution in DMSO which is ready to use in our recommended protocol.

Cyanine3 fluorescent properties are identical to Cy3®, and similar to DyLight 549.

用于 Click Chemistry 的 Cyanine3 染料叠氮化物，是 Cy3® 叠氮化物的类似物。 Cy3® 是使用最广泛的荧光团之一，可以通过各种荧光计、成像仪和显微镜进行检测。 由于固有的高消光系数，Cyanine3 也很容易通过肉眼在凝胶上和溶液中检测到。 这是一种非磺化染料，需要有机助溶剂（DMF、DMSO 或其他）在水中进行有效标记。 该试剂的水溶性版本也可用。

产品既可以作为固体化合物提供，也可以作为 10 mM DMSO 溶液提供，可在我们推荐的方案中使用。

Cyanine3 荧光特性与 Cy3® 相同，与 DyLight 549 相似。

Cy3 absorbance and emission spectra

Cyanine3 azide

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PEP azide

PEP (phenylethynylpyrene), polyaromatic hydrocarbon fluorescent dye for Click-Chemistry labeling.

PEP（苯乙炔基芘），用于 Click-Chemistry 标记的多环芳烃荧光染料。

Cyanine3 amine

Cyanine3 is an fluorophore with free amino group (amino-dye). It can be conjugated with NHS esters, carboxy groups (after activation), and epoxides.

Cy3 是一种带有游离氨基的荧光团（氨基染料）。 它可以与 NHS 酯、羧基（活化后）和环氧化物结合。

BDP 581/591 alkyne

BDP 581/591 is a borondipyrromethene fluorophore which is useful for fluorescence polarization assays, microscopy, and two photon experiments. This alkyne is a derivative for copper-catalyzed Click chemistry.

BDP 581/591 是一种硼二吡咯亚甲基荧光团，可用于荧光偏振测定、显微镜检查和两个光子实验。 该炔烃是铜催化点击化学的衍生物。

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General properties

Appearance: red powder / solution 红粉/溶液
Molecular weight: 575.19
CAS number: 1167421-28-4 (chloride)
Molecular formula: C33H43N6OCl
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), practically insoluble in water (40 mg/L = 60 uM)
Quality control: NMR 1H and HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Kim, S.M.; Park, J.; Kim, M.S.; Song, H.; Jo, A.; Park, H.; Kim, T.S.; Choi, S.H.; Park, S.B. Phenotypic Discovery of an Antivirulence Agent against Vibrio vulnificus via Modulation of Quorum-Sensing Regulator SmcR. ACS Infectious Diseases, 2020, 6(11), 3076–3082. doi: 10.1021/acsinfecdis.0c00587
  2. Tan, M.S.Y.; Davison, D.; Sanchez, M.I.; Anderson, B.M.; Howell, S.; Snijders, A.; Edgington-Mitchell, L.E.; Deu, E. Novel broad-spectrum activity-based probes to profile malarial cysteine proteases. PLoS One, 2020, 15(1), e0227341. doi: 10.1371/journal.pone.0227341
  3. Saqr, A.; Vakili, M.R.; Huang, Y.-H.; Lai, R.; Lavasanifar, A. Development of Traceable Rituximab-Modified PEO-Polyester Micelles by Postinsertion of PEG-phospholipids for Targeting of B-cell Lymphoma. ACS Omega, 2019, 4(20), 18867–18879. doi: 10.1021/acsomega.9b02910
  4. Morimoto, K.; Cole, K.S.; Kourelis, J.; Witt, C.H.; Brown, D.; Krahn, D.; Stegmann, M.; Kaschani, F.; Kaiser, M.; Burton, J.; Mohammed, S.; Yamaguchi-Shinozaki, K.; Weerapana, E.; van der Hoorn, R.A.L. Triazine Probes Target Ascorbate Peroxidases in Plants. Plant Physiology, 2019, 180(4), 1848–1859. doi: 10.1104/pp.19.00481
Cy® is a trademark of Cytiva.

BDP TMR azide,BDP TMR 叠氮化物

BDP TMR azide,BDP TMR 叠氮化物,BDP TMR 是一种硼二吡咯亚甲基荧光团（类似于 BODIPY® TMR），其激发和发射波长与 TAMRA 染料通道相匹配。 该染料具有较长的荧光寿命。

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  • BDP TMR azide

BDP TMR azide

标签：Azides, Fluorescence polarization, Microscopy, BDP TMR
货号 规格 价格 货期
12430 1 mg 110.00$ in stock
22430 5 mg 210.00$ in stock
32430 10 mg 310.00$ in stock
42430 25 mg 410.00$ in stock
52430 50 mg 695.00$ in stock
62430 100 mg 1190.00$ in stock

BDP TMR is a borondipyrromethene fluorophore (analog of BODIPY® TMR) with excitation and emission wavelengths matching TAMRA dye channels. The dye has a long fluorescence lifetime.

This derivative is an azide for Click chemistry labeling.

BDP TMR 是一种硼二吡咯亚甲基荧光团（类似于 BODIPY® TMR），其激发和发射波长与 TAMRA 染料通道相匹配。 该染料具有较长的荧光寿命。

该衍生物是用于点击化学标记的叠氮化物。

Absorption and emission spectra of BODIPY TMR

BDP TMR azide

BDP TMR azide,BDP TMR 叠氮化物相关产品

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

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Coumarin 343 X azide

Coumarin 343 is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by Click chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility, and provides spatial separation between the dye and the biomolecule.

香豆素 343 是一种蓝色荧光团，可作为荧光素 (FAM) 的 FRET 供体。 这种叠氮化物衍生物可以通过点击化学与炔烃结合。 荧光团和叠氮化物基团之间的延伸连接臂增强了溶解度，并提供了染料和生物分子之间的空间分离。

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Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

香豆素 343 是一种蓝色发射染料，可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性，以及染料和官能团之间的空间分离。

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General properties

Appearance: orange to brown solid 橙色至棕色固体
Mass spec M+ increment: 480.2
Molecular weight: 480.32
CAS number: 2183473-25-6; 2373346-19-9
Molecular formula: C24H27BF2N6O2
Solubility: good in most organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16

相关文献：

  1. Koch, P.D.; Quintana, J.; Ahmed, M.S.; Kohler, R.H.; Weissleder, R. Small Molecule Imaging Agent for Mutant KRAS G12C. Advanced Therapeutics, 2021, 4(5), 2000290. doi: 10.1002/adtp.202000290
BODIPY® is a trademark of Life Technologies.

BDP FL azide

BDP FL azide,BDP FL azide 是 BODIPY® FL azide 的类似物，BODIPY® FL azide 是一种适用于 FAM 通道的可点击化学的明亮且光稳定染料。这种发绿光的荧光团与所有类型的 FAM（荧光素）荧光测量仪器兼容。荧光团是硼二吡咯亚甲基类荧光染料的代表，它在水性环境中具有高量子产率，并且对光漂白具有高稳定性。

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  • BDP FL azide

BDP FL azide

标签：BDP FL,Azides,Fluorescence polarization,Microscopy
货号 规格 价格 货期
11430 1 mg 110.00$ in stock
21430 5 mg 210.00$ in stock
31430 10 mg 310.00$ in stock
41430 25 mg 410.00$ in stock
51430 50 mg 695.00$ in stock
61430 100 mg 1190.00$ in stock

BDP FL azide is an analog of BODIPY® FL azide, a Click-chemistry capable bright and photostable dye for FAM channel.

This green-emitting fluorophore is compatible with all types of fluorescence measuring instruments for FAM (fluorescein).

The fluorophore is a representative of borondipyrromethene class of fluorescent dyes, which possess high quantum yields in aqueous environments, and high stability towards photobleaching.

BDP FL azide 是 BODIPY® FL azide 的类似物，BODIPY® FL azide 是一种适用于 FAM 通道的可点击化学的明亮且光稳定染料。

这种发绿光的荧光团与所有类型的 FAM（荧光素）荧光测量仪器兼容。

荧光团是硼二吡咯亚甲基类荧光染料的代表，它在水性环境中具有高量子产率，并且对光漂白具有高稳定性。

BDP FL azide BDP FL azide BDP FL azide BDP FL azide

Absorption and emission spectra of BDP FL

BDP FL azide

BDP FL azide相关产品

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪（甲基四嗪）用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

General properties一般属性

Appearance: orange solid
Molecular weight: 374.20
CAS number: 1379771-95-5, 2243566-18-7
Molecular formula: C17H21BF2N6O
Solubility: soluble in organic solvents (alcohols, DMF, DMSO)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties光谱特性

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Koch, P.D.; Quintana, J.; Ahmed, M.S.; Kohler, R.H.; Weissleder, R. Small Molecule Imaging Agent for Mutant KRAS G12C. Advanced Therapeutics, 2021, 4(5), 2000290. doi: 10.1002/adtp.202000290
  2. Rodríguez-Hakim, M.; Anand, S.; Tajuelo, J.; Yao, Z.; Kannan, A.; Fuller, G.G. Asphaltene-induced spontaneous emulsification: Effects of interfacial co-adsorption and viscoelasticity. Journal of Rheology, 2020, 64(4), 799–816. doi: 10.1122/1.5145307
  3. Antonov, S.A.; Novosadova, E.V.; Kobylansky, A.G.; Tarantul, V.Z.; Grivennikov, I.A. A Hybrid Detection Method Based on Peroxidase-mediated Signal Amplification and Click Chemistry for Highly Sensitive Background-free Immunofluorescent Staining. Journal of Histochemistry & Cytochemistry, 2019, 67(10), 771–782. doi: 10.1369/0022155419864113
  4. Nuhn, L.; Boli, E.; Massa, S.; Vandenberghe, I.; Movahedi, K.; Devreese, B.; Van Ginderachter, J.; De Geest, B.G. Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through SPAAC ligation. Bioconjugate Chemistry, 2018, 29(7), 2394–2405. doi: 10.1021/acs.bioconjchem.8b00319
BODIPY® is a trademark of Life Technologies.

BDP 630/650 azide

BDP 630/650 azide,BDP 630/650 叠氮化物是一种明亮且光稳定的染料叠氮化物，适用于光谱的远红色区域，用于使用 Click 化学进行标记。该染料具有较长的激发态寿命，因此可用于荧光偏振实验。

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  • BDP 630/650 azide

BDP 630/650 azide

标签：Azides,Fluorescence polarization,Microscopy,BDP 630/650
货号 规格 价格 货期
15430 1 mg 110.00$ in stock
25430 5 mg 210.00$ in stock
35430 10 mg 310.00$ in stock
45430 25 mg 410.00$ in stock
55430 50 mg 695.00$ in stock

BDP 630/650 azide is a bright and photostable dye azide for the far red region of the spectrum, for labeling using Click chemistry.

This dye possesses a relatively long lifetime of the excited state, and can therefore be used for fluorescence polarization experiments.

BDP 630/650 叠氮化物是一种明亮且光稳定的染料叠氮化物，适用于光谱的远红色区域，用于使用 Click 化学进行标记。

该染料具有较长的激发态寿命，因此可用于荧光偏振实验。

BDP 630/650 azide BDP 630/650 azide BDP 630/650 azide BDP 630/650 azide

Absorption and emission spectra of BDP 630/650

BDP 630/650 azide

BDP 630/650 azide相关产品

Cy5.5 maleimide

Cy5.5 maleimide is a thiol reactive dye for protein labeling.
Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

TAMRA azide, 5-isomer

TAMRA fluorescent dye azide for Click chemistry.
用于点击化学的 TAMRA 荧光染料叠氮化物。

BDP 630/650 maleimide

BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.
BDP 630/650 马来酰亚胺是一种硫醇反应性、基于硼二吡咯亚甲基的染料，经过调整以匹配 Cyanine5 荧光团的远红通道。

General properties

Appearance: dark colored powder
Mass spec M+ increment: 532.2
Molecular weight: 532.37
CAS number: 2183473-22-3
Molecular formula: C26H23N6BF2O2S
IUPAC name: Boron, [N-​(3-​azidopropyl)​-​2-​[4-​[2-​[5-​[[5-​(2-​thienyl)​-​2H-​pyrrol-​2-​ylidene-​κN]​methyl]​-​1H-​pyrrol-​2-​yl-​κN]​ethenyl]​phenoxy]​acetamidato]​difluoro-​, (T-​4)​- Coordination Compound
Solubility: good in DMSO, DMF, acetonitrile, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

BDP 581/591 azide

BDP 581/591 azide,BDP 581/591 是一种明亮的多功能荧光团，具有相对疏水性。 它具有高亮度、显着的两个光子截面和相对较长的荧光寿命。

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  • Reactive dyes
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  • BDP 581/591 azide

BDP 581/591 azide

标签：Azides,Fluorescence polarization,Microscopy,BDP 581/591
货号 规格 价格 货期
16430 1 mg 110.00$ in stock
26430 5 mg 210.00$ in stock
36430 10 mg 310.00$ in stock
46430 25 mg 410.00$ in stock
56430 50 mg 695.00$ in stock

BDP 581/591 is a bright and versatile fluorophore that is relatively hydrophobic. It has a high brightness, significant two photon cross-section, and relatively long fluorescence lifetime.

The dye reacts with reactive oxygen species (ROS) with the change of its fluorescence. It can be therefore used for intracellular monitoring of ROS.

This is an azide derivative that can be used for the conjugation with both small molecules and biomolecules to construct tracers for fluorescence polarization assays and microscopy probes.

BDP 581/591 是一种明亮的多功能荧光团，具有相对疏水性。 它具有高亮度、显着的两个光子截面和相对较长的荧光寿命。

染料与活性氧 (ROS) 发生反应并改变其荧光。 因此，它可用于细胞内 ROS 的监测。

这是一种叠氮化物衍生物，可用于与小分子和生物分子结合，以构建荧光偏振测定和显微探针的示踪剂。

BDP 581/591 azide BDP 581/591 azide BDP 581/591 azide BDP 581/591 azide

Absorption and emission spectra of BDP 581/591

BDP 581/591 azide

BDP 581/591 azide相关产品

BDP 630/650 alkyne

Alkyne dye for copper catalyzed Click chemistry, containing borondipyrromethene fluorophore BDP 630/650 for red channel.

用于铜催化点击化学的炔烃染料，含有用于红色通道的硼二吡咯亚甲基荧光团 BDP 630/650。

BDP 581/591 NHS ester

NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.

BDP 581/591 硼二吡咯亚甲基荧光团的 NHS 酯衍生物，用于标记蛋白质、肽和其他生物分子。 该染料可用于荧光偏振和双光子实验，并可用作 ROS 探针。

Cy7 NHS ester

Amine reactive NHS ester of near infrared dye Cy7.

近红外染料 Cy7 的胺活性 NHS 酯。

General properties

Appearance: dark solid
Molecular weight: 474.31
Molecular formula: C25H25N6BF2O
Solubility: good in DCM, alcohols, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04