Alkyne hydrazide

Alkyne hydrazide,炔烃酰肼双功能接头试剂是一种衔接分子,可用于将末端炔基连接到醛和酮的羰基上。 在遭受氧化应激的蛋白质中会遇到羰基。 许多小的天然分子也是羰基化合物。 大多数糖类以及 RNA 都含有 1,2-二醇片段,这些片段可以被高碘酸盐氧化成醛类,醛类又与酰肼反应。

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Alkyne hydrazide

标签:Alkynes, Hydrazides,Click chemistry
货号 规格 价格 货期
41770 25 mg 95.00$ in stock
51770 50 mg 195.00$ in stock
61770 100 mg 290.00$ in stock

Alkyne hydrazide bifunctional linker reagent is an adapter molecule which is useful to attach terminal alkyne group to a carbonyl group of aldehydes and ketones. Carbonyl groups are encountered in proteins subjected to oxidative stress. Many small natural molecules are also carbonyl compounds. Most saccharides, as well as RNAs contain 1,2-diol fragments which can be oxidized with periodate to aldehydes, which in turn react with hydrazides.

炔烃酰肼双功能接头试剂是一种衔接分子,可用于将末端炔基连接到醛和酮的羰基上。 在遭受氧化应激的蛋白质中会遇到羰基。 许多小的天然分子也是羰基化合物。 大多数糖类以及 RNA 都含有 1,2-二醇片段,这些片段可以被高碘酸盐氧化成醛类,醛类又与酰肼反应。

Alkyne hydrazide相关产品

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性花青5琥珀酰亚胺酯。

FAM alkyne, 6-isomer

Fluorescein dye alkyne for Click Chemistry, pure 6-isomer.

用于 Click Chemistry 的荧光素染料炔烃,纯 6 异构体。

Cyanine2 NHS ester minimal dye

Cyanine2 NHS ester minimal dye for protein labeling

用于蛋白质标记的 Cy2 NHS 酯最小染料

General properties

Appearance: colorless solid 无色固体
Mass spec M+ increment: 108.1
Molecular weight: 162.62
Molecular formula: C6H11ClN2O
Solubility: good in water, DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

TAMRA hydrazide, 6-isomer

TAMRA hydrazide, 6-isomer,染料酰肼可用于标记醛和酮等羰基化合物。 许多糖可以通过高碘酸氧化转化为羰基化合物。

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  • TAMRA hydrazide, 6-isomer

TAMRA hydrazide, 6-isomer

标签:Hydrazides, TAMRA (TMR  tetramethylrhodamine)
货号 规格 价格 货期
18170 1 mg 110.00$ in stock
28170 5 mg 210.00$ in stock
48170 25 mg 410.00$ in stock
58170 50 mg 695.00$ in stock
68170 100 mg 1190.00$ in stock

Dye hydrazides are useful for the labeling of carbonyl compounds like aldehydes and ketones. Many sugars can be converted to carbonyl compounds by periodate oxidation.

Tetramethylrhodamine (TAMRA) is a xanthene fluorophore. This derivative is a pure 5-isomer of TAMRA bearing hydrazide group for the coupling with carbonyl compounds.

染料酰肼可用于标记醛和酮等羰基化合物。 许多糖可以通过高碘酸氧化转化为羰基化合物。

四甲基罗丹明 (TAMRA) 是一种呫吨荧光团。 该衍生物是 TAMRA 的纯 5-异构体,带有用于与羰基化合物偶联的酰肼基团。

Absorption and emission spectra of 6-TAMRA

TAMRA hydrazide, 6-isomer

TAMRA hydrazide, 6-isomer相关产品

TAMRA NHS ester, 5-isomer

Amine-reactive, activated N-hydroxysuccinimidyl ester of TAMRA dye for the labeling of amine groups of proteins, peptides, and amino-oligonucleotides.

TAMRA 染料的胺反应活性 N-羟基琥珀酰亚胺酯,用于标记蛋白质、肽和氨基寡核苷酸的胺基。

Sulfo-Cyanine5.5 azide

Sulfo-Cyanine5.5 azide is a derivative of water soluble far red emitting fluorescent cyanine dye. The azide group can be conjugated by either copper-catalyzed or copper free Click chemistry. The reagent possesses high aqueous solubility and hydrophilicity, and recommended for the labeling of biomolecules in aqueous environment.

Sulfo-Cy5.5 azide 是水溶性远红荧光花青染料的衍生物。 叠氮基可以通过铜催化或无铜点击化学进行缀合。 该试剂具有高水溶性和亲水性,推荐用于水环境中生物分子的标记。

FAM maleimide, 6-isomer

Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.

荧光素 (FAM) 马来酰亚胺是一种衍生自异构纯 6-FAM 的硫醇活性染料。 荧光素是一种与各种荧光测量仪器兼容的明亮染料。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 426.2
Molecular weight: 480.94
Molecular formula: C25H25N4ClO4
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 541
ε, L⋅mol−1⋅cm−1: 84000
Emission maximum, nm: 567
Fluorescence quantum yield: 0.1
CF260: 0.32
CF280: 0.19

Sulfo-Cyanine3 hydrazide

Sulfo-Cyanine3 hydrazide,Sulfo-Cy3 是 Cy3 染料的硫酸化衍生物,由于其结构中有两个带负电荷的磺基,因此可很好地溶于水。根据其光谱特性,这种橙黄色荧光染料是 Cy™3 的类似物。

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Sulfo-Cyanine3 hydrazide

标签:Hydrazides, Microscopy, sulfo-Cyanine3,Cy3
货号 规格 价格 货期
11370 1 mg 110.00$ in stock
21370 5 mg 290.00$ in stock
41370 25 mg 690.00$ in stock
51370 50 mg 1270.00$ in stock
61370 100 mg 1990.00$ in stock

Sulfo-Cyanine3 is a sulfated derivative of Cyanine3 dye, well soluble in water because of two negatively charged sulfo groups in its structure. By its spectral characteristics, this yellow-orange fluorescent dye is an analog of Cy™3.

Hydrazides efficiently react with aldehydes and ketones resulting in hydrazones, so this compound can be used for conjugation with carbonyl derivatives of biomolecules.

The reaction runs in aqueous conditions, which is important when working with antibodies and proteins. Cys-diol groups in sugars in glycosylated proteins and antibodies can be oxidized into dialdehydes, and cysteine in proteins can be converted with enzymes to formyl glycerol (i. e. reactive groups for conjugation with Sulfo-Cyanine3 hydrazide). Carboxyl groups of aspartic and glutamic acids in proteins and peptides can be also conjugated with Sulfo-Cyanine3 hydrazide in the presence of activating agents: carbodiimide (EDAC) or methyl morpholine (DMTMM) derivatives.

Sulfo-Cy3 是 Cy3 染料的硫酸化衍生物,由于其结构中有两个带负电荷的磺基,因此可很好地溶于水。根据其光谱特性,这种橙黄色荧光染料是 Cy™3 的类似物。

酰肼有效地与醛和酮反应生成腙,因此该化合物可用于与生物分子的羰基衍生物缀合。

反应在水性条件下进行,这在处理抗体和蛋白质时很重要。糖基化蛋白质和抗体中的糖中的 Cys-二醇基团可被氧化成二醛,蛋白质中的半胱氨酸可被酶转化为甲酰基甘油(即与磺基花青 3 酰肼结合的反应基团)。蛋白质和肽中的天冬氨酸和谷氨酸的羧基也可以在活化剂存在的情况下与磺基花青 3 酰肼结合:碳二亚胺 (EDAC) 或甲基吗啉 (DMTMM) 衍生物。

Absorption and emission spectra of sulfo-Cyanine3

Sulfo-Cyanine3 hydrazide

Sulfo-Cyanine3 hydrazide相关产品

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

用于氨基生物分子标记的水溶性磺基-Cy3 SE 活化酯。

Cyanine3 hydrazide

Cyanine3 hydrazide is a carbonyl-reactive dye for Cy3 channel.

Cy3 hydrazide 是 Cy3 通道的羰基反应性染料。

General properties

Appearance: dark red solid 暗红色固体
Molecular weight: 630.78
CAS number: 2144762-62-7
Molecular formula: C30H38N4O7S2
IUPAC name: 3H-​Indolium, 2-​[3-​[1-​(6-​hydrazinyl-​6-​oxohexyl)​-​1,​3-​dihydro-​3,​3-​dimethyl-​5-​sulfo-​2H-​indol-​2-​ylidene]​-​1-​propen-​1-​yl]​-​1,​3,​3-​trimethyl-​5-​sulfo-​, inner salt
Solubility: soluble in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (90%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06
Cy™ is a registered trademark of Cytiva in some countries.

Pyrene hydrazide

Pyrene hydrazide,Pyrene hydrazide是一种羰基活性染料,用于将Pyrene多环芳烃残基连接到醛和酮上。

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Pyrene hydrazide

标签:Hydrazides, Pyrene
货号 规格 价格 货期
13570 1 mg 110.00$ in stock
23570 5 mg 210.00$ in stock
43570 25 mg 410.00$ in stock
53570 50 mg 695.00$ in stock
63570 100 mg 1190.00$ in stock

Pyrene hydrazide is a carbonyl reactive dye for the attachment of pyrene polycyclic aromatic hydrocarbon residues to aldehydes and ketones.

Pyrene is a blue-emitting fluorescent label which is especially useful as a proximity probe. When two pyrene residues are located close to each other, a longer-wavelength excimer fluorescence can be detected. Pyrene can also be FRET donor to other fluorophores. Its excited state possesses an unusually long lifetime of more than 100 ns, which allows to use this fluorophore in time-gated experiments.

Pyrene hydrazide是一种羰基活性染料,用于将Pyrene多环芳烃残基连接到醛和酮上。

Pyrene是一种蓝色荧光标记,特别适合用作邻近探针。 当两个Pyrene残基彼此靠近时,可以检测到更长波长的准分子荧光。Pyrene也可以是其他荧光团的 FRET 供体。 它的激发态具有超过 100 ns 的异常长的寿命,这允许在时间门控实验中使用这种荧光团。

Absorption and emission spectra of pyrene fluorophore

Pyrene hydrazide

Pyrene hydrazide相关产品

Pyrene azide 1

Reagent for fluorescent labeling with pyrene polycyclic aromatic hydrocarbon via Click Chemistry.

通过 Click Chemistry 用Reagent 多环芳烃进行荧光标记的试剂。

Pyrenebutyric acid NHS ester

Pyrene NHS ester for the labeling of biomolecules with pyrene residue. Pyrene is a fluorescent proximity probe which forms excimers, and it is also an anchor group for graphite immobilization.

Pyrene NHS 酯,用于用芘残基标记生物分子。 芘是一种形成准分子的荧光邻近探针,也是石墨固定的锚定基团。

Pyrene maleimide

Pyrene maleimide derivative for the labeling of thiol groups. Pyrene is a useful excimer-forming proximity probe.

用于标记硫醇基团的芘马来酰亚胺衍生物。 芘是一种有用的准分子形成邻近探针。

General properties

Appearance: off white solid 灰白色固体
Mass spec M+ increment: 284.1
Molecular weight: 338.83
Molecular formula: C20H19ClN2O
IUPAC name: 4-(1-pyrenyl)butyric acid hydrazide hydrochloride
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 343; 326; 313; 276; 265; 242; 234
Emission maximum, nm: 377; 397

FAM hydrazide, 6-isomer

FAM hydrazide, 6-isomer,荧光素 (FAM) 是一种呫吨染料,是荧光素染料系列的母体。 这是一种酰肼衍生物,用于标记羰基化合物、醛和酮。

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FAM hydrazide, 6-isomer

标签:FAM (Fluorescein), Hydrazides
货号 规格 价格 货期
15170 1 mg 110.00$ in stock
25170 5 mg 210.00$ in stock
45170 25 mg 410.00$ in stock
55170 50 mg 695.00$ in stock
65170 100 mg 1190.00$ in stock

Fluorescein (FAM) is a xanthene dye, a parent of fluorescein dye series. This is a hydrazide derivative for the labeling of carbonyl compounds, aldehydes, and ketones.

Fluorescein is a bright dye that is compatible with a great number of instruments.

Carbohydrates are also often labeled with hydrazides by a protocol involving their oxidation with periodate first, and reacting with dye hydrazide after it.

荧光素 (FAM) 是一种呫吨染料,是荧光素染料系列的母体。 这是一种酰肼衍生物,用于标记羰基化合物、醛和酮。

荧光素是一种与许多仪器兼容的明亮染料。

碳水化合物也经常用酰肼标记,方法是先用高碘酸盐氧化,然后再与染料酰肼反应。

FAM hydrazide, 6-isomer相关产品

BDP FL hydrazide

Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.

用于 FAM 通道的明亮且光稳定的羰基活性硼二吡咯亚甲基染料。

FAM maleimide, 6-isomer

Fluorescein (FAM) maleimide is a thiol reactive dye derived from isomerically pure 6-FAM. Fluorescein is a bright dye that is compatible with various fluorescence measurement instruments.

荧光素 (FAM) 马来酰亚胺是一种衍生自异构纯 6-FAM 的硫醇活性染料。 荧光素是一种与各种荧光测量仪器兼容的明亮染料。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

General properties

Appearance: yellow/orange solid 黄色/橙色固体
Mass spec M+ increment: 371.1
Molecular weight: 426.81
CAS number: 2183440-65-3 (hydrochloride); 151890-73-2
Molecular formula: C21H15N2ClO6
IUPAC name: Spiro[isobenzofuran-​1(3H)​,​9′-​[9H]​xanthene]​-​6-​carboxylic acid, 3′,​6′-​dihydroxy-​3-​oxo-​, hydrazide, hydrochloride
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

FAM hydrazide, 5-isomer

FAM hydrazide, 5-isomer,FAM (Fluorescein), Hydrazides许多天然和合成分子含有醛或酮羰基。 这些羰基与酰肼反应形成腙。 该反应在中性附近的 pH 值下是自发的,生成的腙非常稳定。

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  • FAM hydrazide, 5-isomer

FAM hydrazide, 5-isomer

标签:FAM (Fluorescein), Hydrazides
货号 规格 价格 货期
14170 1 mg 110.00$ in stock
24170 5 mg 210.00$ in stock
44170 25 mg 410.00$ in stock
54170 50 mg 695.00$ in stock
64170 100 mg 1190.00$ in stock

Many natural and synthetic molecules contain aldehyde or ketone carbonyl groups. These carbonyls react with hydrazides with the formation of hydrazones. The reaction is spontaneous at pH values around neutral, and the resulting hydrazones are very stable.

Compounds containing 1,2-diol function, like sugars, can be oxidized with sodium periodate with the formation of carbonyl compounds for the subsequent modification with hydrazides. This is an efficient method for the labeling of glycoproteins (like antibodies), and polysaccharides.

FAM hydrazide is a hydrazide label for the attachment of fluorescein, a bright dye for 488 nm channel, to carbonyl compounds.

许多天然和合成分子含有醛或酮羰基。 这些羰基与酰肼反应形成腙。 该反应在中性附近的 pH 值下是自发的,生成的腙非常稳定。

含有 1,2-二醇官能团的化合物,如糖,可以用高碘酸钠氧化,形成羰基化合物,然后用酰肼修饰。 这是标记糖蛋白(如抗体)和多糖的有效方法。

FAM hydrazide 是一种酰肼标记物,用于将荧光素(一种 488 nm 通道的明亮染料)连接到羰基化合物上。

Absorption and emission spectra of FAM

FAM hydrazide, 5-isomer

FAM hydrazide, 5-isomer

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃,5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

Alkyne NHS ester (hexynoic acid NHS ester)

Alkyne NHS ester for the labeling of biomolecules with alkyne group for Copper catalyzed Click chemistry.

炔烃 NHS 酯,用于标记具有炔烃基团的生物分子,用于铜催化的点击化学。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

General properties

Appearance: yellow solid 黄色固体
Mass spec M+ increment: 372.07
Molecular weight: 426.81
CAS number: 2183440-64-2
Molecular formula: C21H15N2ClO6
IUPAC name: Spiro[isobenzofuran-​1(3H)​,​9′-​[9H]​xanthene]​-​5-​carboxylic acid, 3′,​6′-​dihydroxy-​3-​oxo-​, hydrazide, hydrochloride
Solubility: good in ethanol, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

Cyanine7.5 hydrazide

Cyanine7.5 hydrazide,Cy7.5 近红外 (NIR) 荧光团的羰基反应性酰肼衍生物。 这种染料具有与 ICG(吲哚菁绿)相似的光谱特性,但具有更高的荧光量子产率。 因此,这种荧光团是体内成像的理想选择。

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  • Cyanine7.5 hydrazide

Cyanine7.5 hydrazide

标签:Cyanine7.5,Cy7.5, Hydrazides, Near infrared (NIR) imaging
货号 规格 价格 货期
16070 1 mg 110.00$ in stock
26070 5 mg 210.00$ in stock
46070 25 mg 410.00$ in stock
56070 50 mg 695.00$ in stock
66070 100 mg 1190.00$ in stock

A carbonyl-reactive hydrazide derivative of Cyanine7.5 near infrared (NIR) fluorophore. This dye has similar spectral properties with ICG (indocyanine green), but has a higher quantum yield of fluorescence. Hence, this fluorophore is ideal for in vivo imaging.

This is a carbonyl-reactive dye which is particularly useful for the labeling of antibodies after periodate oxidation. It also labels other carbonyl compounds (aldehydes and ketones), for example, many saccharides.

Cy7.5 近红外 (NIR) 荧光团的羰基反应性酰肼衍生物。 这种染料具有与 ICG(吲哚菁绿)相似的光谱特性,但具有更高的荧光量子产率。 因此,这种荧光团是体内成像的理想选择。

这是一种羰基反应性染料,特别适用于高碘酸氧化后的抗体标记。 它还标记其他羰基化合物(醛和酮),例如许多糖类。

Cyanine7.5 absorbance and emission spectra

Cyanine7.5 hydrazide

Cyanine7.5 hydrazide相关产品

Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Cy5 hydrazide是醛和酮的活性染料。 它可用于糖部分高碘酸氧化后的糖蛋白的标记。

Cyanine5.5 DBCO

Cyanine5.5 is a far-red / NIR emitting dye that is useful for bioimaging studies. Cyanine5.5 DBCO is a derivative of the dye with a cycloalkyne moiety for Copper free Click chemistry.

Cy5.5 是一种远红/近红外发射染料,可用于生物成像研究。 Cy5.5 DBCO 是具有环炔部分的染料衍生物,用于无铜点击化学。

TAMRA hydrazide, 6-isomer

6-TAMRA azide is a carbonyl reactive hydrazide derivative of tetramethylrhodamine (TAMRA) fluorophore.

6-TAMRA azide 是四甲基罗丹明 (TAMRA) 荧光团的羰基反应性酰肼衍生物。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 644.4
Molecular weight: 735.82
Molecular formula: C45H52Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 788
ε, L⋅mol−1⋅cm−1: 223000
Emission maximum, nm: 808
Fluorescence quantum yield: 0.10

相关文献:

  1. Liu, S.; Dozois, M.D.; Chang, C.N.; Ahmad, A.; Ng, D.L.T.; Hileeto, D.; Liang, H.; Reyad, M.-M.; Boyd, S.; Jones, L.W.; Gu, F.X. Prolonged Ocular Retention of Mucoadhesive Nanoparticle Eye Drop Formulation Enables Treatment of Eye Diseases Using Significantly Reduced Dosage. Molecular Pharmaceutics, 2016, 13(9), 2897–2905. doi: 10.1021/acs.molpharmaceut.6b00445
Cy® is a trademark of GE Healthcare.

Cyanine7 hydrazide

Cyanine7 hydrazide,Cy7 的酰肼衍生物,一种 NIR 荧光染料,是 Cy7® 的类似物。这种七次甲基荧光团包含一个六元环,使聚次甲基链刚性化,与母体结构相比,量子产率提高了 20%。

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  • Reactive dyes
  • Dye hydrazides
  • Cyanine7 hydrazide

Cyanine7 hydrazide

标签:Cyanine7,Cy7, Hydrazides, Near infrared (NIR) imaging
货号 规格 价格 货期
15070 1 mg 110.00$ in stock
25070 5 mg 210.00$ in stock
45070 25 mg 410.00$ in stock
55070 50 mg 695.00$ in stock
65070 100 mg 1190.00$ in stock

Hydrazide derivative of Cyanine7, a NIR fluorescent dye, an analog of Cy7®.

This variety of heptamethine fluorophore contains a six-membered ring rigidizing the polymethine chain which allows to increase quantum yield by 20% compared to parent structure.

Hydrazide reacts quickly and smoothly with aldehydes and ketones yielding stable hydrazone products. This reaction is also good for the labeling of glycoproteins after periodate oxidation.

Cy7 的酰肼衍生物,一种 NIR 荧光染料,是 Cy7® 的类似物。

这种七次甲基荧光团包含一个六元环,使聚次甲基链刚性化,与母体结构相比,量子产率提高了 20%。

酰肼与醛类和酮类反应迅速而平稳,产生稳定的腙产物。 该反应也有利于高碘酸氧化后糖蛋白的标记。

Cyanine7 absorbance and emission spectra

Cyanine7 hydrazide

Cyanine7 hydrazide相关产品

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cy3羧酸。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

Cyanine5.5 maleimide

Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.

Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 544.8
Molecular weight: 635.70
CAS number: 2183440-61-9 (without anion)
Molecular formula: C37H48Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献:

  1. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
Cy® is a trademark of GE Healthcare.

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide,Cy5.5 hydrazide 是一种羰基反应性近红外染料。酰肼与醛和酮等羰基化合物快速反应,形成稳定的腙。该反应可用于制备标记的偶联物。

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  • Cyanine5.5 hydrazide

Cyanine5.5 hydrazide

标签:Cyanine5.5, Cy5.5,Hydrazides, Microscopy
货号 规格 价格 货期
17070 1 mg 110.00$ in stock
27070 5 mg 210.00$ in stock
47070 25 mg 410.00$ in stock
57070 50 mg 695.00$ in stock
67070 100 mg 1190.00$ in stock

Cyanine5.5 hydrazide is a carbonyl-reactive near infrared dye. Hydrazides quickly react with carbonyl compounds, such as aldehydes and ketones, and form stable hydrazones. This reaction is useful for the preparation of labeled conjugates.

Carbonyl groups in biomolecules can form spontaneously after oxidative stress or deamination of proteins. Alternatively, aldehyde groups can be specifically generated by periodate oxidation of sugar residues of glycoproteins, for example antibodies. Antibodies can be oxidized by sodium periodate and labeled with Cyanine5.5 hydrazide to form Cyanine5.5 labeled antibodies. Since sugar residues in antibodies are located far from variable, epitope-binding site, this method is particularly good for the labeling of antibodies.

Cyanine5.5 is a near infrared fluorophore, an analog of Cy5.5®. It is particularly suitable for the applications which require low fluorescence background. The absorption and emission wavelength of the dye exhibit significant tissue penetration, so Cyanine5.5 is suitable for in vivo NIR imaging applications.

Cy5.5 hydrazide 是一种羰基反应性近红外染料。酰肼与醛和酮等羰基化合物快速反应,形成稳定的腙。该反应可用于制备标记的偶联物。

生物分子中的羰基可以在氧化应激或蛋白质脱氨基后自发形成。或者,醛基可以通过糖蛋白(例如抗体)的糖残基的高碘酸氧化特异性地产生。抗体可被高碘酸钠氧化,并用Cyanine5.5酰肼标记,形成Cyanine5.5标记的抗体。由于抗体中的糖残基远离可变的表位结合位点,因此该方法特别适用于标记抗体。

Cy5.5 是一种近红外荧光团,是 Cy5.5® 的类似物。它特别适用于需要低荧光背景的应用。染料的吸收和发射波长表现出显着的组织穿透性,因此 Cy5.5 适用于体内近红外成像应用。

Cyanine5.5 absorbance and emission spectra

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide相关产品

Cyanine7 azide

Near-infrared fluorescent dye for Click Chemistry.

用于点击化学的近红外荧光染料。

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FAM azide, 5-isomer

FAM (fluorescein) azide for Click chemistry, pure 5-isomer.

用于点击化学的 FAM(荧光素)叠氮化物,纯 5 异构体。

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Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cy5.5 是一种远红/近红外荧光团,具有高亲水性和水溶性。 由于出色的摩尔消光系数,该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

Cyanine5.5 hydrazide Add this product to your cart and
get free express delivery

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 669.73
Molecular formula: C40H46Cl2N4O
Solubility: practically insoluble in water (< 2 uM), good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献:

  1. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  2. Zhao, Y.; Wang, Y.; Ran, F.; Cui, Y.; Liu, C.; Zhao, Q.; Gao, Y.; Wang, D.; Wang, S. A comparison between sphere and rod nanoparticles regarding their in vivo biological behavior and pharmacokinetics. Scientific Reports, 2017, 7, 4131. doi: 10.1038/s41598-017-03834-2
Cy® is a trademark of GE Healthcare.

Cyanine5 hydrazide

Cyanine5 hydrazide,Cy5 hydrazide 是一种用于标记醛和酮的活性染料,是 Cy5® 酰肼的类似物。这种染料可以与生物分子中遇到的各种羰基进行平稳且几乎定量的反应。 例子是经受氧化应激的蛋白质、通过高碘酸氧化预活化的糖基化蛋白质(包括抗体)和具有醛部分的寡核苷酸。

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  • Cyanine5 hydrazide

Cyanine5 hydrazide

标签: Cyanine5, Cy5,Hydrazides, Microscopy
货号 规格 价格 货期
13070 1 mg 110.00$ in stock
23070 5 mg 210.00$ in stock
43070 25 mg 410.00$ in stock
53070 50 mg 695.00$ in stock
63070 100 mg 1190.00$ in stock

Cyanine5 hydrazide is a reactive dye for the labeling of aldehydes and ketones, an analog of Cy5® hydrazide.

This dye reacts smoothly and nearly quantitatively with various carbonyl groups encountered in biomolecules. Examples are proteins subjected to oxidative stress, glycosylated proteins pre-activated by periodate oxidation (including antobodies), and oligonucleotides with aldehyde moieties.

Cyanine5 hydrazide replaces carbonyl-reactive Cy5®, DyLight 649 dyes.

Cy5 hydrazide 是一种用于标记醛和酮的活性染料,是 Cy5® 酰肼的类似物。

这种染料可以与生物分子中遇到的各种羰基进行平稳且几乎定量的反应。 例子是经受氧化应激的蛋白质、通过高碘酸氧化预活化的糖基化蛋白质(包括抗体)和具有醛部分的寡核苷酸。

Cyanine5 酰肼替代羰基反应性 Cy5®、DyLight 649 染料。

Cy5 absorbance and emission spectra

Cyanine5 hydrazide

Cyanine5 hydrazide相关产品

ROX reference dye for qPCR

ROX is a passive reference dye for qPCR amplification. The dye can be used to normalize fluorescence intensity of reporter dye in qPCR.

ROX 是用于 qPCR 扩增的被动参考染料。 该染料可用于标准化 qPCR 中报告染料的荧光强度。

FAM DBCO, 6-isomer

Cyclooctyne derivative of fluorescein (FAM) for copper free Click chemistry reaction with azides. Contains pure 6-isomer of fluorescein.

荧光素 (FAM) 的环辛炔衍生物,用于与叠氮化物的无铜点击化学反应。 含有纯6-异构体的荧光素。

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cy5 azide 是一种用 Cyanine5(一种流行的荧光染料)进行 Click Chemistry 标记的试剂。

General properties

Appearance: dark blue powder 深蓝色粉末
Molecular weight: 569.61
CAS number: 1427705-31-4
Molecular formula: C32H42Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献:

  1. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
  2. Imlimthan, S.; Correia, A.; Figueiredo, P.; Lintinen, K.; Balasubramanian, V.; Airaksinen, A.J.; Kostiainen, M.A.; Santos, H.A.; Sarparanta, M. Systematic In Vitro Biocompatibility Studies of Multimodal Cellulose Nanocrystal and Lignin Nanoparticles. Journal of Biomedical Materials Research. Part A, 2020, 108(3), 770–783. doi: 10.1002/jbm.a.36856
  3. Wang, J.; Johnson, A.G.; Lapointe, C.P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A.N.; Puglisi, J.D. eIF5B gates the transition from translation initiation to elongation. Nature, 2019, 573, 605–608. doi: 10.1038/s41586-019-1561-0
  4. Boone, C.; Grove, R.; Adamcova, D.; Braga, C.; Adamec, J. Revealing oxidative damage to enzymes of carbohydrate metabolism in yeast: An integration of 2D DIGE, quantitative proteomics and bioinformatics. Proteomics, 2016, 16(13), 1889–1903. doi: 10.1002/pmic.201500546
Cy® is a trademark of Cytiva.

Cyanine3 hydrazide

Cyanine3 hydrazide,Cy3 hydrazide 是一种羰基活性染料,是 Cy3® 酰肼的类似物。

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  • Cyanine3 hydrazide

Cyanine3 hydrazide

标签:Cyanine3,Cy3, Hydrazides, Microscopy
货号 规格 价格 货期
11070 1 mg 110.00$ in stock
21070 5 mg 210.00$ in stock
41070 25 mg 410.00$ in stock
51070 50 mg 695.00$ in stock
61070 100 mg 1190.00$ in stock

Cyanine3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide.

This reagent allows to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone oxidative stress or deamination, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.

Cyanine3 hydrazide 是一种羰基活性染料,是 Cy3® 酰肼的类似物。

该试剂可以标记各种含羰基分子,例如高碘酸氧化后的抗体和其他糖蛋白、经历氧化应激或脱氨基作用的蛋白质或还原糖。 Cyanine3 与许多荧光仪器兼容。

Cyanine3 absorbance and emission spectra

Cyanine3 hydrazide

Cyanine3 hydrazide相关产品

BDP TR hydrazide

BDP TR hydrazide for the labeling of carbonyl compounds with BDP TR, a borondipyrromethene matching ROX channel.

BDP TR 酰肼,用于用 BDP TR 标记羰基化合物,BDP TR 是一种匹配 ROX 通道的硼二吡咯亚甲基。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cy3 荧光染料的叠氮化物衍生物。

General properties

Appearance: red powder 红色粉末
Molecular weight: 543.57
Molecular formula: C30H40Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H and HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献:

  1. Zhao, Meng and Börner, Richard and Sigel, Roland K. O. and Freisinger, Eva. Site-Specific Dual-Color Labeling of Long RNAs. Methods in Molecular Biology, 2020, 2106, 253–270. doi: 10.1007/978-1-0716-0231-7_16
  2. Zhang, J.; Chetnani, B.; Cormack, E.D.; Alonso, D.; Liu, W.; Mondragon, A.; Fei, J. Specific structural elements of the T-box riboswitch drive the two-step binding of the tRNA ligand. eLife, 2018, 7, e39518. doi: 10.7554/eLife.39518
  3. Cui, Z.; Wu, Y.; Mureev, S.; Alexandrov, K. Oligonucleotide-mediated tRNA sequestration enables one-pot sense codon reassignment in vitro. Nucleic Acids Research, 2018, 46(12), 6387–6400. doi: 10.1093/nar/gky365
  4. Porciani, D.; Cardwell, L.N.; Tawiah, K.d.; Alam, K.K.; Lange, M.J.; Daniels, M.A.; Burke, D.H. Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Nature Communications, 2018, 9(1), 2283. doi: 10.1038/s41467-018-04691-x
Cy® is a trademark of GE Healthcare.

BDP TR hydrazide

BDP TR hydrazide,Hydrazides, BDP TR,BDP TR 是一种用于 ROX 通道的硼二吡咯 (BODIPY®) 染料。 该化合物是一种酰肼反应性衍生物,可用于用 BDP TR 标记醛和酮。

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  • Dye hydrazides
  • BDP TR hydrazide

BDP TR hydrazide

标签:Hydrazides, BDP TR
货号 规格 价格 货期
13470 1 mg 110.00$ in stock
23470 5 mg 210.00$ in stock
43470 25 mg 410.00$ in stock
53470 50 mg 695.00$ in stock
63470 100 mg 1190.00$ in stock

BDP TR is a borondipyrromethene (BODIPY®) dye for ROX channel. This compound is a hydrazide reactive derivative, that can be used for the labeling of aldehydes and ketones with BDP TR.

BDP TR 是一种用于 ROX 通道的硼二吡咯 (BODIPY®) 染料。 该化合物是一种酰肼反应性衍生物,可用于用 BDP TR 标记醛和酮。

Absorption and emission spectra of BDP TR

BDP TR hydrazide

BDP TR hydrazide相关产品

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

香豆素 343 是一种蓝色发射染料,可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性,以及染料和官能团之间的空间分离。

Cyanine7.5 hydrazide

Near infrared fluorophore functionalized with hydrazide moiety. Reactive against carbonyl compounds, useful for the labeling of saccharides, and antibodies after periodate oxidation.

用酰肼部分功能化的近红外荧光团。 对羰基化合物具有反应性,可用于标记糖类和高碘酸盐氧化后的抗体。

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide is a carbonyl reactive NIR dye which is particularly suitable for the labeling of periodate oxidized glycoproteins, i.e. antibodies.

Cy5.5 hydrazide 是一种羰基反应性 NIR 染料,特别适用于标记高碘酸盐氧化糖蛋白,即抗体。

General properties

Appearance: violet powder 紫罗兰粉
Mass spec M+ increment: 419.1
Molecular weight: 474.72
Molecular formula: C21H18N4BClF2O2S
Solubility: good in DMF, DMSO, moderate in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 589
ε, L⋅mol−1⋅cm−1: 69000
Emission maximum, nm: 616
Fluorescence quantum yield: 0.9
CF260: 0.15
CF280: 0.19
BODIPY® is a trademark of Life Technologies in some countries.

BDP R6G hydrazide

BDP R6G hydrazide,BDP R6G 是一种硼二吡咯亚甲基染料,其吸收和发射光谱类似于 R6G(罗丹明 6G)。 这种酰肼是一种羰基反应性化合物,可用于标记醛、酮和大多数碳水化合物(用高碘酸盐氧化)。

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  • BDP R6G hydrazide

BDP R6G hydrazide

标签:Hydrazides, BDP R6G,Reactive dyes,Dye hydrazides
货号 规格 价格 货期
14470 1 mg 110.00$ in stock
24470 5 mg 210.00$ in stock
44470 25 mg 410.00$ in stock
54470 50 mg 695.00$ in stock
64470 100 mg 1190.00$ in stock

BDP R6G is a borondipyrromethene dye whose absorption and emission spectra resemble those of R6G (rhodamine 6G). This hydrazide is a carbonyl-reactive compound that is useful for the labeling of aldehydes, ketones, and most carbohydrates (oxidized with periodate).

BDP R6G 是一种硼二吡咯亚甲基染料,其吸收和发射光谱类似于 R6G(罗丹明 6G)。 这种酰肼是一种羰基反应性化合物,可用于标记醛、酮和大多数碳水化合物(用高碘酸盐氧化)。

Absorption and emission spectra of BDP R6G

BDP R6G hydrazide

BDP R6G hydrazide相关产品

BDP R6G tetrazine

BDP R6G tetrazine is a borondipyrromethene dye with absorption and emission wavelengths similar to rhodamine 6G. It contains tetrazine fragment for iedDA ligation.

BDP R6G 四嗪是一种硼二吡咯亚甲基染料,其吸收和发射波长与罗丹明 6G 相似。 它包含用于 iedDA 连接的四嗪片段。

BDP R6G maleimide

BDP R6G is a borondipyrromethene dye tuned to R6G (rhodamine 6G) channel. This is a thiol reactive maleimide for the labeling of protein cysteine residues, and other thiols.

BDP R6G 是一种调谐到 R6G(罗丹明 6G)通道的硼二吡咯亚甲基染料。 这是一种硫醇反应性马来酰亚胺,用于标记蛋白质半胱氨酸残基和其他硫醇。

BDP R6G NHS ester

BDP R6G is a borondipyrromethene dye which has absorption and emission spectra similar to R6G.

BDP R6G 是一种硼二吡咯亚甲基染料,其吸收和发射光谱与 R6G 相似。

General properties

Appearance: brown powder 棕色粉末
Mass spec M+ increment: 336.1
Molecular weight: 390.62
Molecular formula: C18H18N4BClF2O
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 530
Emission maximum, nm: 548
Fluorescence quantum yield: 0.96
CF260: 0.17
CF280: 0.18

BDP FL hydrazide

BDP FL hydrazide,BDPFL 是一种用于 FAM 通道的明亮且光稳定的染料。 它具有很好的光稳定性,量子产率接近统一。 这种染料非常适合显微镜和荧光偏振测定。

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  • BDP FL hydrazide

BDP FL hydrazide

标签:BDP FL, Hydrazides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
11470 1 mg 110.00$ in stock
21470 5 mg 210.00$ in stock
41470 25 mg 410.00$ in stock
51470 50 mg 695.00$ in stock
61470 100 mg 1190.00$ in stock
BDPFL is a bright and photostable dye for FAM channel. It possesses great photostability, quantum yield approaching unity. This dye is well-suited for microscopy and fluorescence polarization assays.

Hydrazide group provides easy conjugation with carbonyl compounds (aldehydes, and ketones).

BDPFL 是一种用于 FAM 通道的明亮且光稳定的染料。 它具有很好的光稳定性,量子产率接近统一。 这种染料非常适合显微镜和荧光偏振测定。

酰肼基团易于与羰基化合物(醛和酮)结合。

Absorption and emission spectra of BDP FL

BDP FL hydrazide

BDP FL hydrazide相关产品

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能,用于将环辛炔连接到各种分子上。

General properties

Appearance: brown to orange solid 棕色至橙色固体
Molecular weight: 342.58
CAS number: 2183473-45-0
Molecular formula: C14H18BClF2N4O
Solubility: poorly soluble in water (20.2 mM = 6.94 g/L), soluble in polar (DMSO, DMF) organic solvents, methanol, moderately soluble in acetonitrile, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receipt at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献:

  1. Roloff, A.; Nirmalananthan-Budau, N.; Rühle, B.; Borcherding, H.; Thiele, T.; Schedler, U.; Resch-Genger, U. Quantification of Aldehydes on Polymeric Microbead Surfaces via Catch and Release of Reporter Chromophores. Analytical Chemistry, 2019, 91(14), 8827–8834. doi: 10.1021/acs.analchem.8b05515
  2. Liu, R.; Vairaprakash, P.; Lindsey, J.S. Self-assembly with fluorescence readout in a free base dipyrrin–polymer triggered by metal ion binding in aqueous solution. New Journal of Chemistry, 2019, 43(24), 9711–9724. doi: 10.1039/c9nj01787a

BDP 630/650 hydrazide

BDP 630/650 hydrazide,BDP 630/650 是一种基于硼二吡咯亚甲基支架的红色发射染料。 这是一种羰基活性染料,可用于标记醛和酮,包括糖。

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  • BDP 630/650 hydrazide

BDP 630/650 hydrazide

标签:Hydrazides, Fluorescence polarization, BDP 630/650
货号 规格 价格 货期
15470 1 mg 110.00$ in stock
25470 5 mg 210.00$ in stock
45470 25 mg 410.00$ in stock
55470 50 mg 695.00$ in stock
65470 100 mg 1190.00$ in stock

BDP 630/650 is a red emitting dye which is based on the borodipyrromethene scaffold. This is a carbonyl reactive dye that is useful for the labeling of aldehydes and ketones, including sugars.

BDP 630/650 fluorophore is particularly useful for fluorescence polarization assays.

BDP 630/650 是一种基于硼二吡咯亚甲基支架的红色发射染料。 这是一种羰基活性染料,可用于标记醛和酮,包括糖。

BDP 630/650 荧光团特别适用于荧光偏振测定。

Absorption and emission spectra of BDP 630/650

BDP 630/650 hydrazide

BDP 630/650 hydrazide相关产品

BDP 581/591 hydrazide

BDP 581/591 is a multi-purpose dye with bright emission. This is a hydrazide dye for the conjugation with aldehydes and ketones.

BDP 581/591 是一种具有明亮发射的多用途染料。 这是一种用于与醛和酮结合的酰肼染料。

BDP 558/568 NHS ester

BDP 558/568 is a fluorophore for the yellow region of the spectrum. Like other BDP dyes, this fluorophore has high fluorescence quantum yield, brightness, and photostability.

BDP 558/568 是光谱黄色区域的荧光团。 与其他 BDP 染料一样,这种荧光团具有高荧光量子产率、亮度和光稳定性。

BDP 558/568 hydrazide

BDP 558/568 hydrazide is a carbonyl reactive dye with emission in orange/yellow part of the spectrum.

BDP 558/568 酰肼是一种羰基活性染料,在光谱的橙色/黄色部分发射。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 446.1
Molecular weight: 500.76
Molecular formula: C23H20N4BClF2O2S
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

BDP 581/591 hydrazide

BDP 581/591 hydrazide,BDP 581/591 酰肼是一种羰基活性染料。 BDP 581/591 是一种具有明亮发射和出色光稳定性的硼二吡咯亚甲基荧光团。

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  • BDP 581/591 hydrazide

BDP 581/591 hydrazide

标签:Hydrazides, BDP 581/591
货号 规格 价格 货期
16470 1 mg 110.00$ in stock
26470 5 mg 210.00$ in stock
46470 25 mg 410.00$ in stock
56470 50 mg 695.00$ in stock
66470 100 mg 1190.00$ in stock

BDP 581/591 hydrazide is a carbonyl reactive dye. BDP 581/591 is a borondipyrromethene fluorophore with bright emission, and oustanding photostability.

Aldehyde and ketone groups that can be labeled can be obtained by oxidation of 1,2-diol groups in sugars; they are also present in proteins after oxidative stress, and in many small molecules.

BDP 581/591 酰肼是一种羰基活性染料。 BDP 581/591 是一种具有明亮发射和出色光稳定性的硼二吡咯亚甲基荧光团。

可以标记的醛基和酮基可以通过糖中的1,2-二醇基团氧化得到; 它们还存在于氧化应激后的蛋白质中,以及许多小分子中。

Absorption and emission spectra of BDP 581/591

BDP 581/591 hydrazide

BDP 581/591 hydrazide相关产品

BDP FL hydrazide

Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.

用于 FAM 通道的明亮且光稳定的羰基活性硼二吡咯亚甲基染料。

DMSO, labeling grade

Pure dimethyl sulfoxide (DMSO) solvent with quality optimised for Click and other cojugation reactions

纯二甲亚砜 (DMSO) 溶剂,其质量针对 Click 和其他共轭反应进行了优化

Sulfo-Cyanine7 bis-NHS ester

Sulfo-Cyanine7 bis-NHS ester is a bifunctional derivative of water soluble near infrared sulfo-Cyanine7. It contains two activated ester functional groups.

Sulfo-Cy7 双-NHS 酯是水溶性近红外磺基-Cy7 的双功能衍生物。 它含有两个活化的酯官能团。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 388.2
Molecular weight: 442.7
Molecular formula: C22H22N4BClF2O
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04

BDP 558/568 hydrazide

BDP 558/568 hydrazide,醛/酮类型的羰基在天然和合成分子中很常见。 醛和酮可以用酰肼有效标记,形成稳定的腙。该化合物是 BDP 558/568 染料的羰基反应性酰肼衍生物,在黄色光谱范围内发射。

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  • BDP 558/568 hydrazide

BDP 558/568 hydrazide

标签:Hydrazides,BDP 558/568
货号 规格 价格 货期
17470 1 mg 110.00$ in stock
27470 5 mg 210.00$ in stock
47470 25 mg 410.00$ in stock
57470 50 mg 695.00$ in stock
67470 100 mg 1190.00$ in stock

Carbonyl groups of aldehyde/ketone type are very often found in natural and synthetic molecules. Aldehydes and ketones can be efficiently labeled with hydrazides with the formation of stable hydrazones.

This compound is a carbonyl reactive hydrazide derivative of BDP 558/568 dye which has its emission in yellow range of the spectrum.

醛/酮类型的羰基在天然和合成分子中很常见。 醛和酮可以用酰肼有效标记,形成稳定的腙。

该化合物是 BDP 558/568 染料的羰基反应性酰肼衍生物,在黄色光谱范围内发射。

Absorption and emission spectra of BDP 558/568

BDP 558/568 hydrazide

BDP 558/568 hydrazide相关产品

DMF (dimethylformamide), labeling grade

Dry high purity amine free solvent for NHS ester labeling.

用于 NHS 酯标记的干燥高纯度无胺溶剂。

BDP 630/650 hydrazide

A carbonyl reactive borondipyrromethene based dye for the red channel (Cyanine5).

用于红色通道 (Cy5) 的羰基活性硼二吡咯亚甲基染料。

Cyanine3 hydrazide

Cyanine3 hydrazide is a carbonyl-reactive dye for Cy3 channel.

Cyanine3 hydrazide 是 Cy3 通道的羰基反应性染料。

General properties

Appearance: dark colored solid 深色固体
Molecular weight: 396.65
Molecular formula: C16H16N4BClF2OS
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 561
ε, L⋅mol−1⋅cm−1: 84400
Emission maximum, nm: 569
Fluorescence quantum yield: 0.68
CF260: 0.00
CF280: 0.07