产品英文名称: BMP-4,human
产品中文名称:人骨形态发生蛋白4
BMP-4,human产品介绍:
属于TGF-β超家族的骨形态发生蛋白4(bone morphogenetic protein 4, BMP4)具有促进肿瘤发生及侵袭转移的作用,在多种恶性肿瘤组织中表达增加。近年来许多研究表明BMPs不仅能诱导成骨,而且对靶细胞的生长、分化以及 凋亡具有调控作用,BMP4是BMPs中诱导成骨等生物学活性zui强的分子之一,人们发现其在多种肿瘤中表达异常,虽然将其应用于临床中还存在一些需要解决 的问题,但随着研究的深入,BMP4在发病机理、识别治疗靶点、预测疗效等方面应用前景将更加广阔。
» 生物活性在人源293细胞经过SMAD实验鉴定The EC50为 1.0–5.0 ng/ml
» BMP-4产品经过SDS-PAGE 和HPLC双层鉴定纯度大于95%
» BMP-4活性经过人源细胞鉴定,纯度高
» 只限于科学研究,非人体使用
BMP-4,human产品英文简述:
Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-family of structurally related signaling proteins. BMP-4 is involved in the development and maintenance of bone and cartilage. Recombinant human BMP-4, expressed in mammalian cells, is a 32-38 kDa homodimeric glycoprotein. StemRD’s BMP-4 is made in human 293 cells, which renders human-specific post-translational modifications. We purified this product through a series of chromatography including HPLC.
Purity: Greater than 95% by SDS-PAGE and HPLC analysis
Biological Activity: The activity was determined by using a BMP response element (BRE) reporter gene assay. The EC50 ranges from 1 – 5 ng/ml.
For Research Use Only. Not for Use in Humans.
StemRD MGro-500 MSC medium,chemically-defined,间充质干细胞培养基 500mL/瓶
LONZA 04-418Q X-VIVO 15 无血清培养基 1L/瓶
Life Technology 087-0112DK AIM-V? CTS? 无血清细胞培养基(细胞治疗级) 1000mL/瓶
Pall 15950-017 Ultroser Serum Substitute 血清替代品 20mL/瓶
LONZA 12-725F UltraCULTURE Serum-free Medium无血清培养基 500mL/瓶
BD 762165 PAXgene Blood RNA Tube RNA样本收集管 100管/盒
LONZA 50150 SeaKem? Gold Agarose 金琼脂糖粉 125g/瓶
LONZA CC-3162 EGM-2 BulletKit( CC-3156 & CC-4176 )套装 Kit/套
Nunc 159910 175cm2易用培养瓶,PS,已灭菌,瓶盖:过滤盖 30个/箱
LONZA LT07-318 MycoAlert? Mycoplasma Detection Kit支原体检测试剂盒 100Tests/盒
LONZA LT07-418 MycoAlert? Mycoplasma Detection Kit支原体检测试剂盒 50Tests/盒
Lonza 50-650U Kinetic-QCL 192 Test Kit内毒素检测试剂盒 192T/盒
Corning 431080 175cm⒉细胞培养瓶,Angled颈,透气盖 50个/箱
Corning 8388 125mL储液瓶 Storage Bottles,PS,45mm瓶颈,带盖,灭菌,独立包装 24个/箱
Corning 430659 2ml冻存管, 聚丙烯,外旋盖, 可自立圆底 500个/箱
Corning 3290 75cm2 CellBIND Surface培养瓶,已灭菌,透气盖 100个/箱
Corning 3292 175cm2 CellBIND Surface培养瓶,已灭菌,透气盖 50个/箱
BD-Falcon 352360 Cell Strainer, 100μm, Yellow 100um细胞滤网 50个/箱
BD Falcon 352070 50mL锥形离心管,高透明度聚丙烯,袋装 500支/箱
BD Falcon 352096 15mL锥形离心管,高透明度聚丙烯,袋装 500支/箱
BD BioCoat 354234 Matrigel Basement Membrane Matrix(标准型) 10mL/瓶
Cygnus F550 CHO HCP ELISA Kit,3G宿主蛋白检测试剂盒 96T/盒
Cygnus F410 E.coli HCP ELISA Kit 大肠杆菌 96T/盒
Nalgene 5100-0001 Cryo 1℃ Freezing Container梯度降温冻存盒 1个/箱
Nalgene 5026-0909 CryoBoxes 冻存盒 9X9 阵列,管瓶1.2/2.0mL 24个/箱
Nalgene 2250-0130 50L 可高温高压操作的细口大瓶(带手柄) 1个/箱
Nalgene 2319-0050 20L 可高温高压灭菌的细口大瓶(带放水口) 1个/箱
Hyclone SH30084.03 FBS 优等澳洲胎牛血清 500mL/瓶
PeproTech 100-18B-500 Recombinant Human FGF-basic (154 a.a.)因子 500ug/支
Parafilm PM-996 Parafilm? M Laboratory Film 封口膜 12卷/箱