标签： Fractalkine 大鼠重组 CHM-005

Fractalkine, CX3CL1, Neurotactin, CX3C membrane-anchored chemokine, Small inducible cytokine D1, NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine.

Fractalkine 可溶形式对 t 细胞和单核细胞具有趋化性，但对中性粒细胞不具有趋化性。 Fractalkine 膜结合形式促进这些白细胞与内皮细胞的粘附。 Fractalkine 调节内皮的白细胞粘附和迁移过程并与 CX3CR1 结合。 Natural Human Fractalkine 是一种长蛋白，具有延伸的粘蛋白样茎和顶部的趋化因子结构域。 粘蛋白样茎允许它与细胞表面结合。 Fractalkine 基因与一些称为 CCL17 和 CCL22 的 CC 趋化因子一起位于人类第 16 号染色体上。

Fractalkine Rat Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 76 amino acids and having a molecular mass of 8.7kDa.
The Fractalkine is purified by proprietary chromatographic techniques.

Escherichia Coli.

Sterile Filtered White lyophilized powder.

Lyophilized from a 0.2µm filtered concentrated solution in PBS, pH 7.4.

It is recommended to reconstitute the lyophilized Fractalkine in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Greater than 97.0% as determined by -PAGE.

Lyophilized FractalkineRat although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Fractalkine should be stored at 4°C between 2-7 days and for future use below -18°C.
Please prevent freeze-thaw cycles.

QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG

Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-10.0 ng/ml, corresponding to a specific activity of 100,000-200,000units/mg.

Prospec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.