BDP TMR azide,BDP TMR 叠氮化物

BDP TMR azide,BDP TMR 叠氮化物,BDP TMR 是一种硼二吡咯亚甲基荧光团(类似于 BODIPY® TMR),其激发和发射波长与 TAMRA 染料通道相匹配。 该染料具有较长的荧光寿命。

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  • Reactive dyes
  • Dye azides
  • BDP TMR azide

BDP TMR azide

标签:Azides, Fluorescence polarization, Microscopy, BDP TMR
货号 规格 价格 货期
12430 1 mg 110.00$ in stock
22430 5 mg 210.00$ in stock
32430 10 mg 310.00$ in stock
42430 25 mg 410.00$ in stock
52430 50 mg 695.00$ in stock
62430 100 mg 1190.00$ in stock

BDP TMR is a borondipyrromethene fluorophore (analog of BODIPY® TMR) with excitation and emission wavelengths matching TAMRA dye channels. The dye has a long fluorescence lifetime.

This derivative is an azide for Click chemistry labeling.

BDP TMR 是一种硼二吡咯亚甲基荧光团(类似于 BODIPY® TMR),其激发和发射波长与 TAMRA 染料通道相匹配。 该染料具有较长的荧光寿命。

该衍生物是用于点击化学标记的叠氮化物。

Absorption and emission spectra of BODIPY TMR

BDP TMR azide

BDP TMR azide,BDP TMR 叠氮化物相关产品

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

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Coumarin 343 X azide

Coumarin 343 is a blue emitting fluorophore that can serve as a FRET donor for fluorescein (FAM). This azide derivative can be conjugated with alkynes by Click chemistry. An extended linker arm between the fluorophore and the azide group enhances solubility, and provides spatial separation between the dye and the biomolecule.

香豆素 343 是一种蓝色荧光团,可作为荧光素 (FAM) 的 FRET 供体。 这种叠氮化物衍生物可以通过点击化学与炔烃结合。 荧光团和叠氮化物基团之间的延伸连接臂增强了溶解度,并提供了染料和生物分子之间的空间分离。

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Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.

香豆素 343 是一种蓝色发射染料,可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性,以及染料和官能团之间的空间分离。

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General properties

Appearance: orange to brown solid 橙色至棕色固体
Mass spec M+ increment: 480.2
Molecular weight: 480.32
CAS number: 2183473-25-6; 2373346-19-9
Molecular formula: C24H27BF2N6O2
Solubility: good in most organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16

相关文献:

  1. Koch, P.D.; Quintana, J.; Ahmed, M.S.; Kohler, R.H.; Weissleder, R. Small Molecule Imaging Agent for Mutant KRAS G12C. Advanced Therapeutics, 2021, 4(5), 2000290. doi: 10.1002/adtp.202000290
BODIPY® is a trademark of Life Technologies.

BDP FL azide

BDP FL azide,BDP FL azide 是 BODIPY® FL azide 的类似物,BODIPY® FL azide 是一种适用于 FAM 通道的可点击化学的明亮且光稳定染料。这种发绿光的荧光团与所有类型的 FAM(荧光素)荧光测量仪器兼容。荧光团是硼二吡咯亚甲基类荧光染料的代表,它在水性环境中具有高量子产率,并且对光漂白具有高稳定性。

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  • Reactive dyes
  • Dye azides
  • BDP FL azide

BDP FL azide

标签:BDP FL,Azides,Fluorescence polarization,Microscopy
货号 规格 价格 货期
11430 1 mg 110.00$ in stock
21430 5 mg 210.00$ in stock
31430 10 mg 310.00$ in stock
41430 25 mg 410.00$ in stock
51430 50 mg 695.00$ in stock
61430 100 mg 1190.00$ in stock

BDP FL azide is an analog of BODIPY® FL azide, a Click-chemistry capable bright and photostable dye for FAM channel.

This green-emitting fluorophore is compatible with all types of fluorescence measuring instruments for FAM (fluorescein).

The fluorophore is a representative of borondipyrromethene class of fluorescent dyes, which possess high quantum yields in aqueous environments, and high stability towards photobleaching.

BDP FL azide 是 BODIPY® FL azide 的类似物,BODIPY® FL azide 是一种适用于 FAM 通道的可点击化学的明亮且光稳定染料。

这种发绿光的荧光团与所有类型的 FAM(荧光素)荧光测量仪器兼容。

荧光团是硼二吡咯亚甲基类荧光染料的代表,它在水性环境中具有高量子产率,并且对光漂白具有高稳定性。

BDP FL azide BDP FL azide BDP FL azide BDP FL azide

Absorption and emission spectra of BDP FL

BDP FL azide

BDP FL azide相关产品

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪(甲基四嗪)用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cy3 染料 NHS 酯。

General properties一般属性

Appearance: orange solid
Molecular weight: 374.20
CAS number: 1379771-95-5, 2243566-18-7
Molecular formula: C17H21BF2N6O
Solubility: soluble in organic solvents (alcohols, DMF, DMSO)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties光谱特性

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献:

  1. Koch, P.D.; Quintana, J.; Ahmed, M.S.; Kohler, R.H.; Weissleder, R. Small Molecule Imaging Agent for Mutant KRAS G12C. Advanced Therapeutics, 2021, 4(5), 2000290. doi: 10.1002/adtp.202000290
  2. Rodríguez-Hakim, M.; Anand, S.; Tajuelo, J.; Yao, Z.; Kannan, A.; Fuller, G.G. Asphaltene-induced spontaneous emulsification: Effects of interfacial co-adsorption and viscoelasticity. Journal of Rheology, 2020, 64(4), 799–816. doi: 10.1122/1.5145307
  3. Antonov, S.A.; Novosadova, E.V.; Kobylansky, A.G.; Tarantul, V.Z.; Grivennikov, I.A. A Hybrid Detection Method Based on Peroxidase-mediated Signal Amplification and Click Chemistry for Highly Sensitive Background-free Immunofluorescent Staining. Journal of Histochemistry & Cytochemistry, 2019, 67(10), 771–782. doi: 10.1369/0022155419864113
  4. Nuhn, L.; Boli, E.; Massa, S.; Vandenberghe, I.; Movahedi, K.; Devreese, B.; Van Ginderachter, J.; De Geest, B.G. Targeting protumoral tumor-associated macrophages with nanobody-functionalized nanogels through SPAAC ligation. Bioconjugate Chemistry, 2018, 29(7), 2394–2405. doi: 10.1021/acs.bioconjchem.8b00319
BODIPY® is a trademark of Life Technologies.

BDP 630/650 azide

BDP 630/650 azide,BDP 630/650 叠氮化物是一种明亮且光稳定的染料叠氮化物,适用于光谱的远红色区域,用于使用 Click 化学进行标记。该染料具有较长的激发态寿命,因此可用于荧光偏振实验。

  • Products
  • Reactive dyes
  • Dye azides
  • BDP 630/650 azide

BDP 630/650 azide

标签:Azides,Fluorescence polarization,Microscopy,BDP 630/650
货号 规格 价格 货期
15430 1 mg 110.00$ in stock
25430 5 mg 210.00$ in stock
35430 10 mg 310.00$ in stock
45430 25 mg 410.00$ in stock
55430 50 mg 695.00$ in stock

BDP 630/650 azide is a bright and photostable dye azide for the far red region of the spectrum, for labeling using Click chemistry.

This dye possesses a relatively long lifetime of the excited state, and can therefore be used for fluorescence polarization experiments.

BDP 630/650 叠氮化物是一种明亮且光稳定的染料叠氮化物,适用于光谱的远红色区域,用于使用 Click 化学进行标记。

该染料具有较长的激发态寿命,因此可用于荧光偏振实验。

BDP 630/650 azide BDP 630/650 azide BDP 630/650 azide BDP 630/650 azide

Absorption and emission spectra of BDP 630/650

BDP 630/650 azide

BDP 630/650 azide相关产品

Cy5.5 maleimide

Cy5.5 maleimide is a thiol reactive dye for protein labeling.
Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

TAMRA azide, 5-isomer

TAMRA fluorescent dye azide for Click chemistry.
用于点击化学的 TAMRA 荧光染料叠氮化物。

BDP 630/650 maleimide

BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.
BDP 630/650 马来酰亚胺是一种硫醇反应性、基于硼二吡咯亚甲基的染料,经过调整以匹配 Cyanine5 荧光团的远红通道。

General properties

Appearance: dark colored powder
Mass spec M+ increment: 532.2
Molecular weight: 532.37
CAS number: 2183473-22-3
Molecular formula: C26H23N6BF2O2S
IUPAC name: Boron, [N-​(3-​azidopropyl)​-​2-​[4-​[2-​[5-​[[5-​(2-​thienyl)​-​2H-​pyrrol-​2-​ylidene-​κN]​methyl]​-​1H-​pyrrol-​2-​yl-​κN]​ethenyl]​phenoxy]​acetamidato]​difluoro-​, (T-​4)​- Coordination Compound
Solubility: good in DMSO, DMF, acetonitrile, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

BDP 581/591 azide

BDP 581/591 azide,BDP 581/591 是一种明亮的多功能荧光团,具有相对疏水性。 它具有高亮度、显着的两个光子截面和相对较长的荧光寿命。

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  • Reactive dyes
  • Dye azides
  • BDP 581/591 azide

BDP 581/591 azide

标签:Azides,Fluorescence polarization,Microscopy,BDP 581/591
货号 规格 价格 货期
16430 1 mg 110.00$ in stock
26430 5 mg 210.00$ in stock
36430 10 mg 310.00$ in stock
46430 25 mg 410.00$ in stock
56430 50 mg 695.00$ in stock

BDP 581/591 is a bright and versatile fluorophore that is relatively hydrophobic. It has a high brightness, significant two photon cross-section, and relatively long fluorescence lifetime.

The dye reacts with reactive oxygen species (ROS) with the change of its fluorescence. It can be therefore used for intracellular monitoring of ROS.

This is an azide derivative that can be used for the conjugation with both small molecules and biomolecules to construct tracers for fluorescence polarization assays and microscopy probes.

BDP 581/591 是一种明亮的多功能荧光团,具有相对疏水性。 它具有高亮度、显着的两个光子截面和相对较长的荧光寿命。

染料与活性氧 (ROS) 发生反应并改变其荧光。 因此,它可用于细胞内 ROS 的监测。

这是一种叠氮化物衍生物,可用于与小分子和生物分子结合,以构建荧光偏振测定和显微探针的示踪剂。

BDP 581/591 azide BDP 581/591 azide BDP 581/591 azide BDP 581/591 azide

Absorption and emission spectra of BDP 581/591

BDP 581/591 azide

BDP 581/591 azide相关产品

BDP 630/650 alkyne

Alkyne dye for copper catalyzed Click chemistry, containing borondipyrromethene fluorophore BDP 630/650 for red channel.

用于铜催化点击化学的炔烃染料,含有用于红色通道的硼二吡咯亚甲基荧光团 BDP 630/650。

BDP 581/591 NHS ester

NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.

BDP 581/591 硼二吡咯亚甲基荧光团的 NHS 酯衍生物,用于标记蛋白质、肽和其他生物分子。 该染料可用于荧光偏振和双光子实验,并可用作 ROS 探针。

Cy7 NHS ester

Amine reactive NHS ester of near infrared dye Cy7.

近红外染料 Cy7 的胺活性 NHS 酯。

General properties

Appearance: dark solid
Molecular weight: 474.31
Molecular formula: C25H25N6BF2O
Solubility: good in DCM, alcohols, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04

BDP 630/650 X NHS ester

BDP 630/650 X NHS ester,BDP 630/650 是一种硼二吡咯亚甲基荧光团,具有高摩尔消光系数、出色的量子产率和相对较长的激发态寿命。 因此,这种荧光团可用于荧光偏振测定,以检测分子之间的结合。

  • Products
  • Reactive dyes
  • Dye NHS esters
  • BDP 630/650 X NHS ester

BDP 630/650 X NHS ester

标签:NHS esters Fluorescence polarization Microscopy BDP 630/650 Protein labeling
货号 规格 价格 货期
15420 1 mg 110.00$ in stock
25420 5 mg 210.00$ in stock
45420 25 mg 410.00$ in stock
55420 50 mg 695.00$ in stock
65420 100 mg 1190.00$ in stock

BDP 630/650 is a borondipyrromethene fluorophore that has a high molar extinction coefficient, excellent quantum yield, and a relatively long lifetime of the excited state. Due to it, this fluorophore is useful for fluorescence polarization assays that allow to detect binding between molecules.

This is an amine reactive NHS ester. It contains an aminohexanoyl linker between the fluorophore and the reactive group.

BDP 630/650 是一种硼二吡咯亚甲基荧光团,具有高摩尔消光系数、出色的量子产率和相对较长的激发态寿命。 因此,这种荧光团可用于荧光偏振测定,以检测分子之间的结合。

这是一种胺反应性 NHS 酯。 它在荧光团和反应基团之间包含一个氨基己酰基接头。

BDP 630/650 X NHS ester BDP 630/650 X NHS ester BDP 630/650 X NHS ester BDP 630/650 X NHS ester

Absorption and emission spectra of BDP 630/650

BDP 630/650 X NHS ester

BDP 630/650 X NHS ester相关产品

BDP TR X NHS ester

BDP TR X NHS ester is a derivative of BDP TR containing a long linker based on aminohexanoic acid (C6). The dye has absorption and emission close to ROX. The NHS ester function can be used for the conjugation with proteins and peptides.

BDP TR X NHS 酯是 BDP TR 的衍生物,含有一个基于氨基己酸 (C6) 的长接头。 该染料具有接近ROX的吸收和发射。 NHS 酯功能可用于与蛋白质和肽的结合。

FAM tetrazine, 5-isomer

FAM tetrazine (methyltetrazine) for the conjugation with trans-cyclooctenes and cyclopropenes. Pure 5-isomer of fluorescein.

FAM 四嗪(甲基四嗪)用于与反式环辛烯和环丙烯共轭。 荧光素的纯 5-异构体。

dsGreen for Real-Time PCR, 100×

Stock solution of dsGreen for Real-Time PCR, 100×

用于实时 PCR 的 dsGreen 储备溶液,100×

General properties

Appearance: dark colored solid
Mass spec M+ increment: 545.2
Molecular weight: 660.5
CAS number: 2213445-35-1; 380367-48-6
Molecular formula: C33H31N4BF2O6S
IUPAC name: Succinimidyl-6-[2-(p-{(E)-2-[4,4-difluoro-5-(2-thienyl)-3a,4a-diaza-4-bora-s-indacen-3-yl]ethenyl}phenoxy)acetylamino]hexanoate
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

相关文献:

  1. Grätz, L.; Tropmann, K.; Bresinsky, M.; Müller, C.; Bernhardt, G.; Pockes, S. NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells. Scientific Reports, 2020, 10, 13288. doi: 10.1038/s41598-020-70332-3
  2. Gruber, C.G.; Pegoli, A.; Müller, C.; Grätz, L.; She, X.; Keller, M. Differently fluorescence-labelled dibenzodiazepinone-type muscarinic acetylcholine receptor ligands with high M2R affinity. RSC Medicinal Chemistry, 2020, 11(7), 823–832. doi: 10.1039/D0MD00137F
  3. Zhong, X.; Shtukenberg, A.G.; Liu, M.; Olson, I.A.; Weck, M.; Ward, M.D.; Kahr, B. Dislocation Generation by Microparticle Inclusions. Crystal Growth & Design, 2019, 19(11), 6649–6655. doi: 10.1021/acs.cgd.9b01041

BDP 630/650 X NHS ester

BDP 581/591 NHS ester

BDP 581/591 NHS ester,BDP 581/591 是一种硼二吡咯亚甲基染料,具有相对较长的荧光寿命和两个光子激发截面。 它可用于荧光偏振测定。 由于二烯系统的存在,它可以与活性氧(ROS)发生反应并产生荧光变化。

  • Products
  • Reactive dyes
  • Dye NHS esters
  • BDP 581/591 NHS ester

BDP 581/591 NHS ester

标签:NHS esters Fluorescence polarization BDP 581/591 Protein labeling
货号 规格 价格 货期
16420 1 mg 110.00$ in stock
26420 5 mg 210.00$ in stock
46420 25 mg 410.00$ in stock
56420 50 mg 695.00$ in stock
66420 100 mg 1190.00$ in stock

BDP 581/591 is a borondipyrromethene dye that has relatively long fluorescence lifetime and two photon excitation cross section. It is useful for fluorescence polarization assays. Due to the presence of a diene system, it can react with reactive oxygen species (ROS) with a change of fluorescence.

This is the NHS ester derivative for the conjugation with primary and secondary amine groups of proteins, peptides, and other molecules.

BDP 581/591 是一种硼二吡咯亚甲基染料,具有相对较长的荧光寿命和两个光子激发截面。 它可用于荧光偏振测定。 由于二烯系统的存在,它可以与活性氧(ROS)发生反应并产生荧光变化。

这是用于与蛋白质、肽和其他分子的伯胺和仲胺基团结合的 NHS 酯衍生物。

BDP 581/591 NHS ester BDP 581/591 NHS ester BDP 581/591 NHS ester BDP 581/591 NHS ester

Absorption and emission spectra of BDP 581/591

BDP 581/591 NHS ester

BDP 581/591 NHS ester相关产品

BDP TMR NHS ester

Amine reactive NHS ester of BDP TMR, bright borondipyrromethene dye for TAMRA channel especially suitable for fluorescence polarization assays.

BDP TMR 的胺活性 NHS 酯,用于 TAMRA 通道的明亮硼二吡咯亚甲基染料,特别适用于荧光偏振测定。

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.

Cy5.5 未活化的游离酸性花青染料。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cyanine7的胺活性NHS酯。

General properties

Appearance: dark colored solid
Mass spec M+ increment: 374.1
Molecular weight: 489.28
CAS number: 150152-70-8
Molecular formula: C26H22N3BF2O4
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04

相关文献:

  1. Brachi, G.; Ruiz-Ramírez, J.; Dogra, P.; Wang, Z.; Cristini, V.; Ciardelli, G.; Rostomily, R.C.; Ferrari, M.; Mikheev, A.M.; Blanco, E.; Mattu, C. Intratumoral injection of hydrogel-embedded nanoparticles enhances retention in glioblastoma. Nanoscale, 2020, 12(46), 23838–23850. doi: 10.1039/d0nr05053a
  2. Tabe, H.; Sukenobe, K.; Kondo, T.; Sakurai, A.; Maruo, M.; Shimauchi, A.; Hirano, M.; Uno, S.-N.; Kamiya, M.; Urano, Y.; Matsushita, M.; Fujiyoshi, S. Cryogenic Fluorescence Localization Microscopy of Spectrally Selected Individual FRET Pairs in a Water Matrix. The Journal of Physical Chemistry B, 2018, 122(27), 6906–6911. doi: 10.1021/acs.jpcb.8b03977

BDP 576/589 NHS ester

BDP 576/589 NHS ester,BDP 576/589(BODIPY™ 576/589 类似物)是一种硼二吡咯亚甲基染料。 这种疏水染料具有高量子产率和长激发态寿命(约 5 纳秒)。 它可用于测量荧光寿命和荧光偏振以及双光子激光扫描显微镜。

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  • BDP 576/589 NHS ester

BDP 576/589 NHS ester

标签:NHS esters Fluorescence polarization Microscopy BDP 576/589
Cat. # Quantity Price Lead time
1G420 1 mg 110.00$ in stock
2G420 5 mg 210.00$ in stock
4G420 25 mg 410.00$ in stock
5G420 50 mg 695.00$ in stock
6G420 100 mg 1190.00$ 7 days

BDP 576/589 (a BODIPY™ 576/589 analog) is a boron dipyrromethene dye. This hydrophobic dye has high quantum yield and long excited-state lifetime (about 5 nanoseconds). It can be used for measuring fluorescence lifetime and fluorescence polarization and in two-photon laser scanning microscopy.

This reagent is an activated N-hydroxysuccinimide ester of the dye with reactivity to primary and secondary amino groups.

BDP 576/589(BODIPY™ 576/589 类似物)是一种硼二吡咯亚甲基染料。 这种疏水染料具有高量子产率和长激发态寿命(约 5 纳秒)。 它可用于测量荧光寿命和荧光偏振以及双光子激光扫描显微镜。

该试剂是染料的活化 N-羟基琥珀酰亚胺酯,对伯氨基和仲氨基具有反应性。

BDP 576/589 NHS ester BDP 576/589 NHS ester BDP 576/589 NHS ester BDP 576/589 NHS ester

BDP 576/589 NHS ester相关产品

BDP TR X NHS ester

BDP TR X NHS ester is a derivative of BDP TR containing a long linker based on aminohexanoic acid (C6). The dye has absorption and emission close to ROX. The NHS ester function can be used for the conjugation with proteins and peptides.
BDP TR X NHS 酯是 BDP TR 的衍生物,含有一个基于氨基己酸 (C6) 的长接头。 该染料具有接近ROX的吸收和发射。 NHS 酯功能可用于与蛋白质和肽的结合。

Coumarin 343 X NHS ester

Coumarin 343 is a blue emitting dye that can serve as a FRET donor for fluorescein (FAM). This structure features a linker between Coumarin 343 fluorophore, and the functional group. It provides better solubility, and spatial separation between the dye, and the functional group.
香豆素 343 是一种蓝色发射染料,可用作荧光素 (FAM) 的 FRET 供体。 这种结构的特点是香豆素 343 荧光团和官能团之间有一个接头。 它提供了更好的溶解性,以及染料和官能团之间的空间分离。

FAM amine, 5-isomer

Amino derivative of fluorescein, pure 5-isomer. Contains a linker arm between the aliphatic amine group, and the fluorophore. Useful for the labeling via enzymatic transamination, for the reactions with electrophilic reagents, and for reductive amination.
荧光素的氨基衍生物,纯 5-异构体。 在脂肪胺基团和荧光团之间包含一个连接臂。 可用于通过酶促氨基转移进行标记、与亲电子试剂的反应以及还原胺化。

General properties

Appearance: dark colored crystals
Mass spec M+ increment: 328.1
Molecular weight: 426.18
CAS number: 201998-61-0
Molecular formula: C20H17N4BF2O4
Solubility: soluble in polar organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 580
ε, L⋅mol−1⋅cm−1: 98000
Emission maximum, nm: 592
Fluorescence quantum yield: 0.13

BDP TMR amine

BDP TMR amine,BDP TMR 是 TAMRA 通道的染料。 然而,与原始 TAMRA 不同,它具有非常好的量子产率,因此具有高亮度。

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  • BDP TMR amine

BDP TMR amine

标签:Amines, Fluorescence polarization, Microscopy, BDP TMR
货号 规格 价格 货期
124C0 1 mg 110.00$ in stock
224C0 5 mg 210.00$ in stock
424C0 25 mg 410.00$ in stock
524C0 50 mg 695.00$ in stock
624C0 100 mg 1190.00$ in stock

BDP TMR is a dye for TAMRA channel. Unlike original TAMRA, it however possesses very good quantum yield, and therefore high brightness.

This derivative contains a primary amine group that can be conjugated with various electrophiles. It can also participate in enzymatic transamination reaction.

BDP TMR 是 TAMRA 通道的染料。 然而,与原始 TAMRA 不同,它具有非常好的量子产率,因此具有高亮度。

该衍生物含有一个伯胺基团,可以与各种亲电子试剂共轭。 还可参与酶促转氨反应。

Absorption and emission spectra of BODIPY TMR

BDP TMR amine

BDP TMR amine相关产品

BDP 581/591 amine

BDP 581/591 fluorophore derivative with free amine group for the conjugation with electrophilic reagents, and enzymatic transamination.

BDP 581/591 具有游离胺基团的荧光团衍生物,用于与亲电试剂偶联和酶促转氨。

Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cyanine5.5 是一种远红/近红外荧光团,具有高亲水性和水溶性。 由于出色的摩尔消光系数,该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

Cyanine3 NHS ester

Amine-reactive Cyanine3 dye NHS ester.

胺反应性 Cyanine3 染料 NHS 酯。

General properties

Appearance: violet solid 紫罗兰色固体
Molecular weight: 532.86
CAS number: 2183473-08-5 (free base)
Molecular formula: C27H36BClF2N4O2
IUPAC name: 1,3-dimethyl-2(6-aminohexylaminocarbonyl)-4,4-difluoro-5-(4-methoxyphenyl)borondipyrromethene
Solubility: good in alcohols, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16

BDP 630/650 amine

BDP 630/650 amine,BDP 630/650 是一种远红光发射、基于硼二吡咯亚甲基的荧光团。 该染料经过调整以匹配标准 Cy5 通道,可用作 Cyanine5 和 sulfo-Cyanine5 的替代品。 与花青相比,BDP 630/650 具有更长的荧光寿命,这对于荧光各向异性测量很重要。

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  • BDP 630/650 amine

BDP 630/650 amine

标签:Amines, Fluorescence polarization, BDP 630/650
货号 规格 价格 货期
154C0 1 mg 110.00$ in stock
254C0 5 mg 210.00$ in stock
454C0 25 mg 410.00$ in stock
554C0 50 mg 695.00$ in stock
654C0 100 mg 1190.00$ in stock

BDP 630/650 is a far red emitting, borondipyrromethene based fluorophore. The dye is tuned to match the standard Cy5 channel, and can be used as an alternative to Cyanine5 and sulfo-Cyanine5. Compared to cyanines, BDP 630/650 possesses a longer fluorescence lifetime which is important for fluorescence anisotropy measurements.

BDP 630/650 has a brightness similar to cyanines, and an exceptional photostability.

This amine derivative is useful for the reaction with electrophiles, and for enzymatic transamination labeling.

BDP 630/650 是一种远红光发射、基于硼二吡咯亚甲基的荧光团。 该染料经过调整以匹配标准 Cy5 通道,可用作 Cyanine5 和 sulfo-Cyanine5 的替代品。 与花青相比,BDP 630/650 具有更长的荧光寿命,这对于荧光各向异性测量很重要。

BDP 630/650 具有与花青相似的亮度和出色的光稳定性。

该胺衍生物可用于与亲电试剂的反应以及酶促氨基转移标记。

Absorption and emission spectra of BDP 630/650

BDP 630/650 amine

BDP 630/650 amine相关产品

TAMRA amine, 5-isomer

TAMRA (tetramethylrhodamine) dye, pure 5-isomer, with an amine group for the conjugation with electrophilic reagents (NHS esters, epoxides, etc).

TAMRA(四甲基罗丹明)染料,纯 5-异构体,带有一个胺基,可与亲电子试剂(NHS 酯、环氧化物等)结合。

BDP TR amine

BDP TR borondipyrromethene dye with a free amine group for the conjugation with electrophilic reagents and enzymatic transamination reaction. BDP TR is a bright dye for ROX channel.

带有游离胺基的 BDP TR 硼二吡咯亚甲基染料,用于与亲电试剂偶联和酶促转氨反应。 BDP TR 是 ROX 通道的明亮染料。

BDP 650/665 X NHS ester

Amine reactive of BDP 650/665, a borondipyrromethene dye for Cy5 channel, possessing a high molar extinction coefficient, and a good emission quantum yield.

BDP 650/665 的胺反应物,一种用于 Cy5 通道的硼二吡咯亚甲基染料,具有高摩尔消光系数和良好的发射量子产率。

General properties

Appearance: dark violet solid 深紫色固体
Molecular weight: 584.92
Molecular formula: C29H32N4BClF2O2S
Solubility: moderately soluble in water (81 mM = 47.2 mg/mL), well soluble in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

相关文献:

  1. Zhang, Y.; Zhu, X.; Chen, X.; Chen, Q.; Zhou, W.; Guo, Q.; Lu, Y.; Li, C.; Zhang, Y.; Liang, D.; Sun, T.; Wei, X.; Jiang, C. Activated Platelets-Targeting Micelles with Controlled Drug Release for Effective Treatment of Primary and Metastatic Triple Negative Breast Cancer. Advanced Functional Materials, 2019, 29(13), 1806620. doi: 10.1002/adfm.201806620
  2. Zhang, Y.; Guo, Z.; Cao, Z.; Zhou, W.; Zhang, Y.; Chen, Q.; Lu, Y.; Chen, X.; Guo, Q.; Li, C.; Liang, D.; Sun, T.; Jiang, C. Endogenous albumin-mediated delivery of redox-responsive paclitaxel-loaded micelles for targeted cancer therapy. Biomaterials, 2018, 183, 243–257. doi: 10.1016/j.biomaterials.2018.06.002

BDP 630/650 carboxylic acid

BDP 630/650 carboxylic acid,BDP 630/650 是一种基于硼二吡咯亚甲基支架的亮远红色荧光团。 这是一种羧酸衍生物,可以被活化以与胺偶联。 它也可以用作阴性实验中的对照,或者当不需要染料的化学附着时。

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BDP 630/650 carboxylic acid

标签:Carboxylic acids, Fluorescence polarization, BDP 630/650
货号 规格 价格 货期
15490 1 mg 110.00$ in stock
25490 5 mg 210.00$ in stock
45490 25 mg 410.00$ in stock
55490 50 mg 695.00$ in stock
65490 100 mg 1190.00$ in stock

BDP 630/650 is a bright far red fluorophore based on borondipyrromethene scaffold. This is a carboxylic acid derivative that can be activated for the coupling with amines. It can also be used as a control in negative experiments, or when chemical attachment of the dye is not necessary.

BDP 630/650 是一种基于硼二吡咯亚甲基支架的亮远红色荧光团。 这是一种羧酸衍生物,可以被活化以与胺偶联。 它也可以用作阴性实验中的对照,或者当不需要染料的化学附着时。

Absorption and emission spectra of BDP 630/650

BDP 630/650 carboxylic acid

BDP 630/650 carboxylic acid相关产品

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

Sulfo-Cyanine5.5 amine

Sulfo-Cyanine5.5 is a far red/NIR fluorophore possessing high hydrophilicity and aqueous solubility. The dye displays good brightness in far red region due to outstanding molar extinction coefficient. This is amine derivative which is reactive towards electrophiles. It can also be used for enzymatic transamination labeling.

Sulfo-Cy5.5 是一种远红/近红外荧光团,具有高亲水性和水溶性。 由于出色的摩尔消光系数,该染料在远红色区域显示出良好的亮度。 这是对亲电试剂有反应性的胺衍生物。 它也可用于酶促转氨标记。

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer – an alkyne derivative of fluorescein dye for Click Chemistry.

FAM 炔烃,5 异构体 – 用于 Click Chemistry 的荧光素染料的炔烃衍生物。

General properties

Appearance: dark powder 黑粉
Molecular weight: 450.27
Molecular formula: C23H17N2BF2O3S
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

相关文献:

  1. Pfister, J.; Lichius, A.; Summer, D.; Haas, H.; Kanagasundaram, T.; Kopka, K.; Decristoforo, C. Live-cell imaging with Aspergillus fumigatus-specific fluorescent siderophore conjugates. Scientific Reports, 2020, 10, 15519. doi: 10.1038/s41598-020-72452-2
  2. Mitronova, G.Y.; Lukinavičius, G.; Butkevich, A.N.; Kohl, T.; Belov, V.N.; Lehnart, S.E.; Hell, S.W. High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors. Scientific Reports, 2017, 7, 12319. doi: 10.1038/s41598-017-12468-3

BDP FL hydrazide

BDP FL hydrazide,BDPFL 是一种用于 FAM 通道的明亮且光稳定的染料。 它具有很好的光稳定性,量子产率接近统一。 这种染料非常适合显微镜和荧光偏振测定。

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BDP FL hydrazide

标签:BDP FL, Hydrazides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
11470 1 mg 110.00$ in stock
21470 5 mg 210.00$ in stock
41470 25 mg 410.00$ in stock
51470 50 mg 695.00$ in stock
61470 100 mg 1190.00$ in stock
BDPFL is a bright and photostable dye for FAM channel. It possesses great photostability, quantum yield approaching unity. This dye is well-suited for microscopy and fluorescence polarization assays.

Hydrazide group provides easy conjugation with carbonyl compounds (aldehydes, and ketones).

BDPFL 是一种用于 FAM 通道的明亮且光稳定的染料。 它具有很好的光稳定性,量子产率接近统一。 这种染料非常适合显微镜和荧光偏振测定。

酰肼基团易于与羰基化合物(醛和酮)结合。

Absorption and emission spectra of BDP FL

BDP FL hydrazide

BDP FL hydrazide相关产品

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

Cyanine5 maleimide

Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

Cy5 马来酰亚胺与硫醇反应生成染料标记的偶联物。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能,用于将环辛炔连接到各种分子上。

General properties

Appearance: brown to orange solid 棕色至橙色固体
Molecular weight: 342.58
CAS number: 2183473-45-0
Molecular formula: C14H18BClF2N4O
Solubility: poorly soluble in water (20.2 mM = 6.94 g/L), soluble in polar (DMSO, DMF) organic solvents, methanol, moderately soluble in acetonitrile, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receipt at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献:

  1. Roloff, A.; Nirmalananthan-Budau, N.; Rühle, B.; Borcherding, H.; Thiele, T.; Schedler, U.; Resch-Genger, U. Quantification of Aldehydes on Polymeric Microbead Surfaces via Catch and Release of Reporter Chromophores. Analytical Chemistry, 2019, 91(14), 8827–8834. doi: 10.1021/acs.analchem.8b05515
  2. Liu, R.; Vairaprakash, P.; Lindsey, J.S. Self-assembly with fluorescence readout in a free base dipyrrin–polymer triggered by metal ion binding in aqueous solution. New Journal of Chemistry, 2019, 43(24), 9711–9724. doi: 10.1039/c9nj01787a

BDP 630/650 hydrazide

BDP 630/650 hydrazide,BDP 630/650 是一种基于硼二吡咯亚甲基支架的红色发射染料。 这是一种羰基活性染料,可用于标记醛和酮,包括糖。

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  • BDP 630/650 hydrazide

BDP 630/650 hydrazide

标签:Hydrazides, Fluorescence polarization, BDP 630/650
货号 规格 价格 货期
15470 1 mg 110.00$ in stock
25470 5 mg 210.00$ in stock
45470 25 mg 410.00$ in stock
55470 50 mg 695.00$ in stock
65470 100 mg 1190.00$ in stock

BDP 630/650 is a red emitting dye which is based on the borodipyrromethene scaffold. This is a carbonyl reactive dye that is useful for the labeling of aldehydes and ketones, including sugars.

BDP 630/650 fluorophore is particularly useful for fluorescence polarization assays.

BDP 630/650 是一种基于硼二吡咯亚甲基支架的红色发射染料。 这是一种羰基活性染料,可用于标记醛和酮,包括糖。

BDP 630/650 荧光团特别适用于荧光偏振测定。

Absorption and emission spectra of BDP 630/650

BDP 630/650 hydrazide

BDP 630/650 hydrazide相关产品

BDP 581/591 hydrazide

BDP 581/591 is a multi-purpose dye with bright emission. This is a hydrazide dye for the conjugation with aldehydes and ketones.

BDP 581/591 是一种具有明亮发射的多用途染料。 这是一种用于与醛和酮结合的酰肼染料。

BDP 558/568 NHS ester

BDP 558/568 is a fluorophore for the yellow region of the spectrum. Like other BDP dyes, this fluorophore has high fluorescence quantum yield, brightness, and photostability.

BDP 558/568 是光谱黄色区域的荧光团。 与其他 BDP 染料一样,这种荧光团具有高荧光量子产率、亮度和光稳定性。

BDP 558/568 hydrazide

BDP 558/568 hydrazide is a carbonyl reactive dye with emission in orange/yellow part of the spectrum.

BDP 558/568 酰肼是一种羰基活性染料,在光谱的橙色/黄色部分发射。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 446.1
Molecular weight: 500.76
Molecular formula: C23H20N4BClF2O2S
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

FAM maleimide, 6-isomer

FAM maleimide, 6-isomer,FAM(荧光素)是一种明亮的荧光团,可与各种荧光检测仪器兼容。 FAM 是一种通用染料,可用于显微镜检查、qPCR 和许多其他方法以及基于 FRET 和荧光偏振的结合测定。

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  • FAM maleimide, 6-isomer

FAM maleimide, 6-isomer

标签:FAM (Fluorescein), Maleimides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
24180 5 mg in stock
44180 25 mg 160.00$ in stock
54180 50 mg 270.00$ in stock
64180 100 mg 420.00$ in stock

FAM (fluorescein) is a bright fluorophore which is compatible with various fluorescence detection instruments. FAM is a universal dye that is useful for microscopy, qPCR and many other methods as well as for FRET-based and fluorescence polarization based binding assays.

FAM maleimide is a thiol reactive dye for the labeling of proteins, peptides, and other thiolated molecules.

FAM(荧光素)是一种明亮的荧光团,可与各种荧光检测仪器兼容。 FAM 是一种通用染料,可用于显微镜检查、qPCR 和许多其他方法以及基于 FRET 和荧光偏振的结合测定。

FAM 马来酰亚胺是一种硫醇活性染料,用于标记蛋白质、肽和其他硫醇化分子。

Fluorescein (FAM) absorbance and emission spectra

FAM maleimide, 6-isomer

FAM maleimide, 6-isomer相关产品

BDP FL amine

Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.

BDP FL 染料的氨基衍生物,用于 FAM(荧光素)488 nm 通道的硼二吡咯亚甲基染料。

Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Cy5 hydrazide是醛和酮的活性染料。 它可用于糖部分高碘酸氧化后的糖蛋白的标记。

Cyanine5.5 alkyne

Cyanine5.5 alkyne is a NIR (near infrared) dye azide for both copper-catalyzed, and copper-free Click Chemistry.

Cy5.5 炔烃是一种 NIR(近红外)染料叠氮化物,适用于铜催化和无铜点击化学。

General properties

Appearance: yellow solid 黄色固体
Mass spec M+ increment: 498.4
Molecular weight: 498.44
Molecular formula: C27H18N2O8
Solubility: good in DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献:

  1. Woodford, M.R.; Baker-Williams, A.J.; Sager, R.A.; Backe, S.J.; Blanden, A.R.; Hashmi, F.; Kancherla, P.; Gori, A.; Loiselle, D.R.; Castelli, M.; Serapian, S.A.; Colombo, G.; Haystead, T.A.; Jensen, S.M.; Stetler-Stevenson, W.G.; Loh, S.N.; Schmidt, L.S.; Linehan, W.M.; Bah, A.; Bourboulia, D.; Bratslavsky, G.; Mollapour, M. The tumor suppressor folliculin inhibits lactate dehydrogenase A and regulates the Warburg effect. Nature Structural & Molecular Biology, 2021, 28(8), 662–670. doi: 10.1038/s41594-021-00633-2
  2. Nojoumi, S.; Ma, Y.; Schwagerus, S.; Hackenberger, C.P.R.; Budisa, N. In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation. International Journal of Molecular Sciences, 2019, 20(9), 2299. doi: 10.3390/ijms20092299
  3. Sauer, F.; Klemm, T.; Kollampally, R.B.; Tessmer, I.; Nair, R.K.; Popov, N.; Kisker, C. Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities. Molecular Cell, 2019, 74(3), 421–435.e10. doi: 10.1016/j.molcel.2019.02.029
  4. Yu, C.; Tang, J.; Loredo, A.; Chen, Y.; Jung, S.Y.; Jain, A.; Gordon, A.; Xiao, H. Proximity-Induced Site-Specific Antibody Conjugation. Bioconjugate Chemistry, 2018, 29(11), 3522–3526. doi: 10.1021/acs.bioconjchem.8b00680

BDP TMR maleimide

BDP TMR maleimide,BDP TMR 是用于 TAMRA 通道的明亮硼二吡咯亚甲基荧光团。 这种马来酰亚胺衍生物适合与硫醇基团结合,例如 在蛋白质侧链中。

  • Products
  • Reactive dyes
  • Dye maleimides
  • BDP TMR maleimide

BDP TMR maleimide

标签:Maleimides, Fluorescence polarization, Microscopy, BDP TMR
货号 规格 价格 货期
12480 1 mg 110.00$ in stock
22480 5 mg 210.00$ in stock
42480 25 mg 410.00$ in stock
52480 50 mg 695.00$ in stock
62480 100 mg 1190.00$ in stock

BDP TMR is a bright borondipyrromethene fluorophore for the TAMRA channel. This maleimide derivative is suitable for conjuction with thiol groups as e.g. in protein side chains.

BDP TMR 是用于 TAMRA 通道的明亮硼二吡咯亚甲基荧光团。 这种马来酰亚胺衍生物适合与硫醇基团结合,例如 在蛋白质侧链中。

Absorption and emission spectra of BDP TMR

BDP TMR maleimide

BDP TMR maleimide相关产品

BDP FL hydrazide

Bright and photostable, carbonyl reactive borondipyrromethene dye for FAM channel.

用于 FAM 通道的明亮且光稳定的羰基活性硼二吡咯亚甲基染料。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯,一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

BDP TR NHS ester

BDP TR is a borondipyrromethene dye. A bright and photostable fluorophore with high quantum yield.

BDP TR 是一种硼二吡咯亚甲基染料。 具有高量子产率的明亮且光稳定的荧光团。

General properties

Appearance: purple powder  紫色粉末
Mass spec M+ increment: 520.2
Molecular weight: 520.34
CAS number: 2183473-34-7
Molecular formula: C27H27BF2N4O4
IUPAC name: 2-(2-(N-maleimidoethylaminocarbonylethyl))-1,3-dimethyl-5-(4-methoxyphenyl)-4,4-difluoroborondipyrromethene
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16

相关文献:

  1. Gusev, I.D.; Firsov, A.M.; Chertkova, R.V.; Kotova, E.A.; Dolgikh, D.A.; Kirpichnikov, M.P.; Antonenko, Y.N. Study of Interaction of Fluorescent Cytochrome C with Liposomes, Mitochondria, and Mitoplasts by Fluorescence Correlation Spectroscopy. Russian Journal of Bioorganic Chemistry, 2020, 46(6), 1162–1171. doi: 10.1134/S1068162020060084

BDP FL maleimide

BDP FL maleimide,硫醇活性 BDP FL 马来酰亚胺是一种用于蛋白质标记的活性染料,其结构与 BODIPY® FL 马来酰亚胺相同。

  • Products
  • Reactive dyes
  • Dye maleimides
  • BDP FL maleimide

BDP FL maleimide

标签:BDP FL, Maleimides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
11480 1 mg 110.00$ in stock
21480 5 mg 210.00$ in stock
41480 25 mg 410.00$ in stock
51480 50 mg 695.00$ in stock
61480 100 mg 1190.00$ in stock

Thiol reactive BDP FL maleimide is a reactive dye for protein labeling, which has identical structure with BODIPY® FL maleimide.

BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar to fluorescein (FAM). However, this dye exhibits very high photostability. It is non-charged, and has low molecular weight. Its brightness is similar to fluorescein, R110 and xanthene dye derivatives.

This fluorophore is ideal for fluorescent microscopy and many other applications. The fluorophore can substitute fluorescein for almost any application, and it is compatible with any FAM-capable fluorescent instrumentation.

硫醇活性 BDP FL 马来酰亚胺是一种用于蛋白质标记的活性染料,其结构与 BODIPY® FL 马来酰亚胺相同。

BDP FL 是一种硼二吡咯亚甲基染料,其吸收光谱和荧光光谱与荧光素 (FAM) 相似。 然而,这种染料表现出非常高的光稳定性。 它是不带电的,并且具有低分子量。 其亮度类似于荧光素、R110 和呫吨染料衍生物。

这种荧光团是荧光显微镜和许多其他应用的理想选择。 荧光团几乎可以在任何应用中替代荧光素,并且与任何支持 FAM 的荧光仪器兼容。

Absorption and emission spectra of BDP FL

BDP FL maleimide

BDP FL maleimide相关产品

Cyanine5.5 maleimide

Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.

Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

EDC, coupling grade

Water soluble carbodiimide for the coupling of carboxylic acids with amines.

用于羧酸与胺偶联的水溶性碳二亚胺。

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

General properties

Appearance: orange solid  橙色固体
Mass spec M+ increment: 414.1
Molecular weight: 414.21
CAS number: 773859-49-7
Molecular formula: C20H21BF2N4O3
Solubility: Good in organic solvents (DMF, DMSO), limited in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献:

  1. Koch, S.; Seinen, A.-B.; Kamel, M.; Kuckla, D.; Monzel, C.; Kedrov, A.; Driessen, A.J.M. Single-molecule analysis of dynamics and interactions: of the SecYEG translocon. FEBS Journal, 2021, 288(7), 2203–2221. doi: 10.1111/febs.15596
  2. São Pedro, M.N.; Azevedo, A.M.; Aires-Barros, M.R.; Soares, R.R.G. Minimizing the influence of fluorescent tags on IgG partition in PEG-salt aqueous two-phase systems for rapid screening applications. Biotechnology Journal, 2019, 14(8), 1800640. doi: 10.1002/biot.201800640
  3. Doh, J.K.; White, J.D.; Zane, H.K.; Chang, Y.H.; López, C.S.; Enns, C.A.; Beatty, K.E. VIPER is a genetically encoded peptide tag for fluorescence and electron microscopy. Proceedings of the National Academy of Sciences of the United States of America, 2018, 115, 12961–12966. doi: 10.1073/pnas.1808626115
  4. Buecheler, J.W.; Winzer, M.; Tonillo, J.; Weber, C.A.; Gieseler, H. Impact of Payload Hydrophobicity on Stability of Antibody-Drug-Conjugates. Molecular Pharmaceutics, 2018, 15(7), 2656–2664. doi: 10.1021/acs.molpharmaceut.8b00177
BODIPY® is a trademark of Life Technologies.

BDP 630/650 maleimide

BDP 630/650 maleimide,BDP 630/650 是一种用于 Cy5 通道的远红色发射硼二吡咯亚甲基荧光团。 由于其激发态的寿命相对较长,这种染料对于荧光寿命相关的测量特别有用。

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  • Reactive dyes
  • Dye maleimides
  • BDP 630/650 maleimide

BDP 630/650 maleimide

标签:Maleimides, Fluorescence polarization, BDP 630/650
货号 规格 价格 货期
15480 1 mg 110.00$ in stock
25480 5 mg 210.00$ in stock
45480 25 mg 410.00$ in stock
55480 50 mg 695.00$ in stock
65480 100 mg 1190.00$ in stock

BDP 630/650 is a far red emitting borondipyrromethene based fluorophore for the Cyanine5 channel. Because of its relatively long lifetime of the excited state, this dye is particularly useful for fluorescence lifetime related measurements.

The reactive maleimide moiety allows to attach the dye to thiol groups in biomolecules, especially proteins and peptides.

BDP 630/650 是一种用于 Cy5 通道的远红色发射硼二吡咯亚甲基荧光团。 由于其激发态的寿命相对较长,这种染料对于荧光寿命相关的测量特别有用。

反应性马来酰亚胺部分允许将染料连接到生物分子中的硫醇基团,尤其是蛋白质和肽。

Absorption and emission spectra of BDP 630/650

BDP 630/650 maleimide

BDP 630/650 maleimide相关产品

BDP 650/665 X NHS ester

Amine reactive of BDP 650/665, a borondipyrromethene dye for Cy5 channel, possessing a high molar extinction coefficient, and a good emission quantum yield.

BDP 650/665 的胺反应物,一种用于 Cy5 通道的硼二吡咯亚甲基染料,具有高摩尔消光系数和良好的发射量子产率。

Cyanine5.5 azide

Far red / near infrared fluorescent Cyanine5.5 dye derivative for Click Chemistry.

用于 Click Chemistry 的远红/近红外荧光 Cy5.5 染料衍生物。

Azidobutyric acid NHS ester

Activated ester for azido labeling of peptides and proteins.

用于肽和蛋白质的叠氮基标记的活化酯。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 572.2
Molecular weight: 572.39
CAS number: 2183473-31-4
Molecular formula: C29H23N4BF2O4S
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

BDP 581/591 maleimide

BDP 581/591 maleimide,BDP 581/591 马来酰亚胺是一种硫醇活性染料,用于标记蛋白质和肽的巯基。

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  • Dye maleimides
  • BDP 581/591 maleimide

BDP 581/591 maleimide

标签:Maleimides, Fluorescence polarization, BDP 581/591
货号 规格 价格 货期
16480 1 mg 110.00$ in stock
26480 5 mg 210.00$ in stock
46480 25 mg 410.00$ in stock
56480 50 mg 695.00$ in stock
66480 100 mg 1190.00$ in stock
BDP 581/591 maleimide is a thiol reactive dye for the labeling of sulfhydryl groups of proteins and peptides.

The dye is useful for a variety of applications, such as microscopy, fluorescence polarization experiments, and even ROS detection (upon reaction with ROS, the dye changes its fluorescence).

BDP 581/591 马来酰亚胺是一种硫醇活性染料,用于标记蛋白质和肽的巯基。

该染料可用于多种应用,例如显微镜检查、荧光偏振实验,甚至 ROS 检测(与 ROS 反应后,染料会改变其荧光)。

Absorption and emission spectra of BDP 581/591

BDP 581/591 maleimide

BDP 581/591 maleimide相关产品

BDP 581/591 NHS ester

NHS ester derivative of BDP 581/591 borondipyrromethene fluorophore for the labeling of proteins, peptides, and other biomolecules. The dye is useful for fluorescence polarization and two-photon experiments, and as a ROS probe.

BDP 581/591 硼二吡咯亚甲基荧光团的 NHS 酯衍生物,用于标记蛋白质、肽和其他生物分子。 该染料可用于荧光偏振和双光子实验,并可用作 ROS 探针。

Cyanine7 maleimide

Cyanine7 maleimide is a sulfhydryl-reactive NIR dye.

Cy7 马来酰亚胺是一种巯基反应性 NIR 染料。

Sulfo-Cyanine5.5 maleimide

Sulfo-Cyanine5.5 is a water-soluble far red emitting dye. This is a thiol reactive maleimide derivative of sulfo-Cyanine5.5. It is recommended for the labeling of sensitive proteins.

Sulfo-Cyanine5.5 是一种水溶性远红发射染料。 这是 sulfo-Cy5.5 的硫醇反应性马来酰亚胺衍生物。 推荐用于敏感蛋白的标记。

General properties

Appearance: dark colored solid 深色固体
Molecular weight: 514.33
Molecular formula: C28H25N4BF2O3
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04

FAM alkyne, 6-isomer

FAM alkyne, 6-isomer,用于 Click Chemistry 的 FAM(荧光素)荧光团的炔烃衍生物。 纯 (97+%) 单一 6 异构体。荧光素是一种明亮的荧光团,与许多不同的荧光仪器兼容。

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  • Dye alkynes
  • FAM alkyne, 6-isomer

FAM alkyne, 6-isomer

标签:FAM (Fluorescein), Alkynes, Fluorescence polarization, Microscopy
货号 规格 价格 货期
A51B0 1 mg 80.00$ in stock
B51B0 5 mg 100.00$ in stock
C51B0 10 mg 150.00$ in stock
D51B0 25 mg 295.00$ in stock
E51B0 50 mg 450.00$ in stock
F51B0 100 mg 780.00$ in stock

Alkyne derivative of FAM (fluorescein) fluorophore for Click Chemistry. Pure (97+%) single 6-isomer.

Fluorescein is a bright fluorophore which is compatible with a number of different fluorescent instruments.

用于 Click Chemistry 的 FAM(荧光素)荧光团的炔烃衍生物。 纯 (97+%) 单一 6 异构体。

荧光素是一种明亮的荧光团,与许多不同的荧光仪器兼容。

FAM absorbance and emission spectra

FAM alkyne, 6-isomer

FAM alkyne, 6-isomer相关产品

Sulfo-Cyanine3 alkyne

A water soluble dye alkyne for copper-catalyzed Click Chemistry. The fluorophore Sulfo-Cyanine3 is a bright and photostable dye for the Cy3® channel.

一种用于铜催化点击化学的水溶性染料炔烃。 荧光团 Sulfo-Cyanine3 是一种用于 Cy3® 通道的明亮且光稳定的染料。

BDP FL alkyne

Borondipyrromethene dye alkyne for Click Chemistry. Bright and photostable dye for FAM channel.

用于 Click Chemistry 的硼二吡咯亚甲基染料炔烃。 用于 FAM 通道的明亮和光稳定染料。

TAMRA azide, 5-isomer

TAMRA fluorescent dye azide for Click chemistry.

用于点击化学的 TAMRA 荧光染料叠氮化物。

General properties

Appearance: yellow solid 黄色固体
Molecular weight: 413.38
CAS number: 478801-49-9
Molecular formula: C25H15O6N
Solubility: good in aqueous buffers (pH > 8), alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 490
ε, L⋅mol−1⋅cm−1: 80000
Emission maximum, nm: 513
Fluorescence quantum yield: 0.93
CF260: 0.20
CF280: 0.17

相关文献:

  1. Machado, Y.; Duinkerken, S.; Hoepflinger, V.; Mayr, M.; Korotchenko, E.; Kurtaj, A.; Pablos, I.; Steiner, M.; Stoecklinger, A.; Lübbers, J.; Schmid, M.; Ritter, U.; Scheiblhofer, S.; Ablinger, M.; Wally, V.; Hochmann, S.; Raninger, A.M.; Strunk, D.; van Kooyk, Y.; Thalhamer, J.; Weiss, R. Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy. Journal of Controlled Release, 2017, 266, 87–99. doi: 10.1016/j.jconrel.2017.09.020
  2. Shi, P.; Ju, E.; Yan, Z.; Gao, N.; Wang, J.; Hou, J.; Zhang, Y.; Ren, J.; Qu, X. Spatiotemporal control of cell-cell reversible interactions using molecular engineering. Nature communications, 2016, 7, 13088. doi: 10.1038/ncomms13088

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer,用于铜催化点击化学的 FAM(荧光素)炔烃,高纯度 (97+%) 5-异构体。 该化合物具有显着的水溶性。

  • Products
  • Reactive dyes
  • Dye alkynes
  • FAM alkyne, 5-isomer

FAM alkyne, 5-isomer

标签:FAM (Fluorescein), Alkynes, Fluorescence polarization, Microscopy
货号 规格 价格 货期
A41B0 1 mg 80.00$ in stock
B41B0 5 mg 100.00$ in stock
C41B0 10 mg 150.00$ in stock
D41B0 25 mg 295.00$ in stock
E41B0 50 mg 450.00$ in stock
F41B0 100 mg 780.00$ in stock

FAM (fluorescein) alkyne for copper-catalyzed Click chemistry, high purity (97+%) 5-isomer. The compound possesses significant aqueous solubility.

用于铜催化点击化学的 FAM(荧光素)炔烃,高纯度 (97+%) 5-异构体。 该化合物具有显着的水溶性。

FAM absorbance and emission spectra

FAM alkyne, 5-isomer

FAM alkyne, 5-isomer

Sulfo-Cyanine3 NHS ester

Water soluble sulfo-Cyanine3 SE activated ester for amino-biomolecule labeling.

用于氨基生物分子标记的水溶性磺基-Cy3 SE 活化酯。

BDP 630/650 maleimide

BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.

BDP 630/650 马来酰亚胺是一种硫醇反应性、基于硼二吡咯亚甲基的染料,经过调整以匹配 Cyanine5 荧光团的远红通道。

Sulfo-Cyanine3 maleimide

Water soluble thiol-reactive derivative of Sulfo-Cyanine3, a Cy3 analog.

Sulfo-Cyanine3 的水溶性硫醇反应性衍生物,一种 Cy3 类似物。

General properties

Appearance: yellow solid 黄色固体
Molecular weight: 413.38
CAS number: 510758-19-7
Molecular formula: C25H15O6N
Solubility: good in aqueous buffers (pH > 8), alcohols, DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 490
ε, L⋅mol−1⋅cm−1: 80000
Emission maximum, nm: 513
Fluorescence quantum yield: 0.93
CF260: 0.20
CF280: 0.17

相关文献:

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Research Square, preprint. doi: 10.21203/rs.3.rs-237483/v1
  2. Kamzabek, D.; Le Dé, B.; Coche-Guérente, L.; Miomandre, F.; Dubacheva, G.V. Thermoresponsive Fluorescence Switches Based on Au@pNIPAM Nanoparticles. Langmuir, 2021, 37(37), 10971–10978. doi: 10.1021/acs.langmuir.1c01397
  3. Sokolova, V.; Mekky, G.; van der Meer, S.B.; Seeds, M.C.; Atala, A.J.; Epple, M. Transport of ultrasmall gold nanoparticles (2 nm) across the blood-brain barrier in a six-cell brain spheroid model. Scientific Reports, 2020, 10, 18033. doi: 10.1038/s41598-020-75125-2
  4. Warminski, M.; Kowalska, J.; Jemielity, J. Solid-Phase Synthesis of RNA 5′-Azides and Their Application for Labeling, Ligation, and Cyclization Via Click Chemistry. Current Protocols in Nucleic Acid Chemistry, 2020, 82(1), e112. doi: 10.1002/cpnc.112

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BDP TR alkyne,BDP TR炔烃

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  • Dye alkynes
  • BDP TR alkyne

BDP TR alkyne

标签:Alkynes, BDP TR, Fluorescence polarization,荧光偏振
货号 规格 价格 货期
A34B0 1 mg 110.00$ in stock
B34B0 5 mg 210.00$ in stock
C34B0 10 mg 310.00$ in stock
D34B0 25 mg 410.00$ in stock
E34B0 50 mg 695.00$ in stock
F34B0 100 mg 1190.00$ in stock

BDP TR is a borondipyrromethene fluorophore for ROX channel. This is a universal fluorophore that can be used for microscopy, fluorescence polarization assay, and other applications.

This derivative is a terminal alkyne for copper-catalyzed Click chemistry.

BDP TR 是一种用于 ROX 通道的硼二吡咯亚甲基荧光团。 这是一种通用荧光团,可用于显微镜检查、荧光偏振测定和其他应用。

该衍生物是铜催化点击化学的末端炔烃。

Absorption and emission spectra of BODIPY TR

BDP TR alkyne

BDP TR alkyne,BDP TR炔烃相关产品

BDP TR amine

BDP TR borondipyrromethene dye with a free amine group for the conjugation with electrophilic reagents and enzymatic transamination reaction. BDP TR is a bright dye for ROX channel.

带有游离胺基的 BDP TR 硼二吡咯亚甲基染料,用于与亲电试剂偶联和酶促转氨反应。 BDP TR 是 ROX 通道的明亮染料。

FAM alkyne, 6-isomer

Fluorescein dye alkyne for Click Chemistry, pure 6-isomer.

用于 Click Chemistry 的荧光素染料炔烃,纯 6 异构体。

TAMRA alkyne, 5-isomer

Alkyne derivative of TAMRA dye, pure 5-isomer for CuAAC.

TAMRA 染料的炔烃衍生物,CuAAC 的纯 5-异构体。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 461.1
Molecular weight: 461.29
CAS number: 2006345-35-1
Molecular formula: C24H18N3BF2O2S
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 589
ε, L⋅mol−1⋅cm−1: 69000
Emission maximum, nm: 616
Fluorescence quantum yield: 0.9
CF260: 0.15
CF280: 0.19

BDP TMR alkyne,BDP TMR 炔烃

BDP TMR alkyne,BDP TMR 炔烃,BDP TMR 是 TAMRA 通道的荧光团。 由于高量子产率,它比 TAMRA 亮得多。 这种炔烃染料可以通过铜催化的点击化学反应与叠氮化物结合。

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  • BDP TMR alkyne

BDP TMR alkyne

标签:Alkynes, Fluorescence polarization, Microscopy, 显微镜,BDP TMR
货号 规格 价格 货期
A24B0 1 mg 110.00$ in stock
B24B0 5 mg 210.00$ in stock
C24B0 10 mg 310.00$ in stock
D24B0 25 mg 410.00$ in stock
E24B0 50 mg 695.00$ in stock
F24B0 100 mg 1190.00$ 5 days

BDP TMR is a fluorophore for TAMRA channel. Due to high quantum yield, it is much brighter than TAMRA. This alkyne dye can be conjugated with azides by copper-catalyzed Click Chemistry reaction.

BDP TMR 是 TAMRA 通道的荧光团。 由于高量子产率,它比 TAMRA 亮得多。 这种炔烃染料可以通过铜催化的点击化学反应与叠氮化物结合。

Absorption and emission spectra of BODIPY TMR

BDP TMR alkyne

BDP TMR alkyne,BDP TMR 炔烃

FAM alkyne, 6-isomer

Fluorescein dye alkyne for Click Chemistry, pure 6-isomer.

用于 Click Chemistry 的荧光素染料炔烃,纯 6 异构体。

BDP TMR azide

Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.

具有叠氮基的硼二吡咯亚甲基染料。 光谱特性类似于 TAMRA 染料。 由于荧光寿命长,BDP TMR 特别适用于荧光偏振测量。

BDP 650/665 alkyne

BDP 650/665 alkyne is a red emitting BODIPY dye derivative carrying a terminal alkyne group for a copper catalyzed conjugation with azides. Absorption and emission spectra of BDP 650/665 are designed to fit Cy5 channel of various instruments.

BDP 650/665 炔烃是一种发红光的 BODIPY 染料衍生物,带有一个末端炔烃基团,用于铜催化与叠氮化物的共轭。 BDP 650/665 的吸收和发射光谱旨在适应各种仪器的 Cy5 通道。

General properties

Appearance: green-black crystals 绿黑色晶体
Mass spec M+ increment: 435.19
Molecular weight: 435.28
Molecular formula: C24H24BF2N3O2
Solubility: good in chlorinated organic solvents, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16
BODIPY® is a trademark of Life Technologies.

BDP FL alkyne,BDP FL 炔烃

BDP FL alkyne,BDP FL 炔烃,BDP FL 的炔烃衍生物,BODIPY® FL 炔烃的类似物。 BDP FL 是一种硼二吡咯亚甲基染料,一种明亮且光稳定的荧光团,在荧光素 (FAM) 通道中发射。 与 FAM 不同,BDP FL 非常耐光。 它的亮度类似于荧光素。

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  • BDP FL alkyne

BDP FL alkyne

标签:BDP FL, Alkynes, Fluorescence polarization, Microscopy,Dye alkynes,炔烃
货号 规格 价格 货期
A14B0 1 mg 110.00$ in stock
B14B0 5 mg 210.00$ in stock
C14B0 10 mg 310.00$ in stock
D14B0 25 mg 410.00$ in stock
E14B0 50 mg 695.00$ in stock
F14B0 100 mg 1190.00$ in stock

Alkyne derivative of BDP FL, an analog of BODIPY® FL alkyne. BDP FL is a borondipyrromethene dye, a bright and photostable fluorophore which emits in fluorescein (FAM) channel. Unlike FAM, BDP FL is very photostable. Its brightness is similar to fluorescein.

This alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.

BDP FL 的炔烃衍生物,BODIPY® FL 炔烃的类似物。 BDP FL 是一种硼二吡咯亚甲基染料,一种明亮且光稳定的荧光团,在荧光素 (FAM) 通道中发射。 与 FAM 不同,BDP FL 非常耐光。 它的亮度类似于荧光素。

这种炔烃可以通过铜催化的点击化学与许多含叠氮化物的分子结合。

BDP FL absorption and emission spectra

BDP FL alkyne

BDP FL alkyne,BDP FL 炔烃相关产品

Cyanine3 alkyne

Cyanine3 alkyne is a fluorescent dye alkyne for Click Chemistry.

Cy3 炔烃是一种用于 Click Chemistry 的荧光染料炔烃。

3-Ethynyl perylene

Alkyne derivative of ultra-bright and photostable perylene fluorophore.

超亮和光稳定苝荧光团的炔烃衍生物。

Cyanine3 azide

Azide derivative of Cyanine3 fluorescent dye for Click Chemistry.

用于 Click Chemistry 的 Cyanine3 荧光染料的叠氮化物衍生物。

General properties

Appearance: orange solid 橙色固体
Mass spec M+ increment: 329.1
Molecular weight: 329.15
CAS number: 302795-84-2, 2006345-30-6
Molecular formula: C17H18BF2N3O
IUPAC name:
Solubility: Good in organic solvents (DMF, DMSO, dichlromethane), limited in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献:

  1. Charoen-Rajapark, P.; Clarke, D.R. Confocal microscopy observations of electrical pre-breakdown of bi-layer elastomer dielectrics. Extreme Mechanics Letters, 2021, 49, 101473. doi: 10.1016/j.eml.2021.101473
  2. Abukar, T.; Rahmani, S.; Thompson, N.K.; Antonescu, C.N.; Wakarchuk, W.W. Development of BODIPY labelled sialic acids as sialyltransferase substrates for direct detection of terminal galactose on N- and O-linked glycans. Carbohydrate Research, 2021, 500, 108249. doi: 10.1016/j.carres.2021.108249
  3. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  4. Du, T.; Buenbrazo, N.; Kell, L.; Rahmani, S.; Sim, L.; Withers, S.G.; DeFrees, S.; Wakarchuk, W.;. A Bacterial Expression Platform for Production of Therapeutic Proteins Containing Human-like O-Linked Glycans. Cell Chemical Biology, 2019, 26(2), 203–212.e5. doi: 10.1016/j.chembiol.2018.10.017
BODIPY® is a trademark of Life Technologies

BDP 630/650 alkyne,BDP 630/650 炔烃

BDP 630/650 alkyne,BDP 630/650 炔烃,BDP 630/650 是一种与 Cy5 通道匹配的红色荧光团。 该染料可用于荧光偏振测定。 它也非常耐光。

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  • BDP 630/650 alkyne

BDP 630/650 alkyne

标签:Fluorescence polarization, Microscopy, BDP 630/650,炔烃
货号 规格 价格 货期
A54B0 1 mg 110.00$ in stock
B54B0 5 mg 210.00$ in stock
C54B0 10 mg 310.00$ in stock
D54B0 25 mg 410.00$ in stock
E54B0 50 mg 695.00$ in stock
F54B0 100 mg 1190.00$ in stock

BDP 630/650 is a red emitting fluorophore matching the Cyanine5 channel. The dye is useful for fluorescence polarization assays. It is also remarkably photostable.

The terminal alkyne group can be conjugated with various azides by copper catalyzed Click chemistry.

BDP 630/650 是一种与 Cy5 通道匹配的红色荧光团。 该染料可用于荧光偏振测定。 它也非常耐光。

末端炔基可以通过铜催化的点击化学与各种叠氮化物缀合。

Absorption and emission spectra of BDP 630/650

BDP 630/650 alkyne

BDP 630/650 alkyne,BDP 630/650 炔烃相关产品

BDP TMR azide

Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.

具有叠氮基的硼二吡咯亚甲基染料。 光谱特性类似于 TAMRA 染料。 由于荧光寿命长,BDP TMR 特别适用于荧光偏振测量。

Sulfo-Cyanine3 tetrazine

Water soluble sulfo-Cyanine3 dye tetrazine derivative for TCO ligation labeling with trans-cyclooctenes.

水溶性磺基-Cy3 染料四嗪衍生物,用于用反式环辛烯进行 TCO 连接标记。

EdU (5-ethynyl-2′-deoxyuridine)

EdU is a nucleoside which is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by Click chemistry reaction with fluorescent dye azides to reveal cell proliferation.

EdU 是一种核苷,可通过细胞酶掺入复制的 DNA 中。 之后,细胞中所含的 DNA 可以通过与荧光染料叠氮化物的 Click 化学反应进行显色,以揭示细胞增殖情况。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 487.1
Molecular weight: 487.33
CAS number: 2006345-38-4
Molecular formula: C26H20N3BF2O2S
Solubility: good in DMF, DMSO, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 628
ε, L⋅mol−1⋅cm−1: 97000
Emission maximum, nm: 642
Fluorescence quantum yield: 0.91
CF260: 0.029
CF280: 0.035

FAM azide, 6-isomer,FAM 叠氮化物,6-isomer

FAM azide, 6-isomer,FAM 叠氮化物,6-isomer,FAM(荧光素)叠氮化物。 固体和 10 mM DMSO 溶液,用于点击化学的标记试剂。

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  • FAM azide, 6-isomer

FAM azide, 6-isomer

标签:FAM (Fluorescein), Azides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
15130 100 uL, 10 mM/DMSO 80.00$ in stock
35130 500 uL, 10 mM/DMSO 100.00$ in stock
45130 1 mL, 10 mM/DMSO 150.00$ in stock
A5130 1 mg 80.00$ in stock
B5130 5 mg 100.00$ in stock
C5130 10 mg 150.00$ in stock
D5130 25 mg 295.00$ 5 days
E5130 50 mg 450.00$ in stock
F5130 100 mg 780.00$ in stock

FAM (fluorescein) azide. solid and 10 mM solution in DMSO, labeling reagent for Click chemistry.

Pure 6-isomer.

Can replace DyLight 488.

FAM(荧光素)叠氮化物。 固体和 10 mM DMSO 溶液,用于点击化学的标记试剂。

纯 6 异构体。

可替代 DyLight 488。

FAM azide, 6-isomer,FAM 叠氮化物,6-isomer相关产品

Alkyne NHS ester (hexynoic acid NHS ester)

Alkyne NHS ester for the labeling of biomolecules with alkyne group for Copper catalyzed Click chemistry.

炔烃 NHS 酯,用于标记具有炔烃基团的生物分子,用于铜催化的点击化学。

ROX reference dye for qPCR

ROX is a passive reference dye for qPCR amplification. The dye can be used to normalize fluorescence intensity of reporter dye in qPCR.

ROX 是用于 qPCR 扩增的被动参考染料。 该染料可用于标准化 qPCR 中报告染料的荧光强度。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

General properties

Appearance: yellowish crystals 淡黄色晶体
Molecular weight: 458.42
CAS number: 1386385-76-7
Molecular formula: C24H18N4O6
Solubility: soluble in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献:

  1. Haider, N.; Dutt, P.; van de Kooij, B.; Yaffe, M.B.; Stambolic, V. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. bioRxiv, preprint. doi: 10.1101/516971
  2. Lee, R.; Erstling, J.A.; Hinckley, J.A.; Chapman, D.V.; Wiesner, U.B. Addressing Particle Compositional Heterogeneities in Super-Resolution-Enhanced Live-Cell Ratiometric pH Sensing with Ultrasmall Fluorescent Core–Shell Aluminosilicate Nanoparticles. Advanced Functional Materials, 2021, 31(45), 2106144. doi: 10.1002/adfm.202106144
  3. Ramey-Ward, A.N.; Su, H.; Salaita, K. Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis. ACS Applied Materials & Interfaces, 2020, 12(32), 35903–35917. doi: 10.1021/acsami.0c08871
  4. Reed, S.A.; Brzovic, D.A.; Takasaki, S.S.; Boyko, K.V.; Antos, J.M. Efficient Sortase-Mediated Ligation Using a Common C-Terminal Fusion Tag. Bioconjugate Chemistry, 2020, 31(5), 1463–1473. doi: 10.1021/acs.bioconjchem.0c00156

FAM azide, 5-isomer,FAM 叠氮化物,5-isomer

FAM azide, 5-isomer,FAM 叠氮化物,5-isomer,FAM 叠氮化物既可作为固体化合物使用,也可作为 10 mM DMSO 溶液提供,可用于我们推荐的标记方案。 本品为纯5-异构体。 FAM 是 DyLight 488 的替代品。

  • Products
  • Reactive dyes
  • Dye azides
  • FAM azide, 5-isomer

FAM azide, 5-isomer

标签:FAM (Fluorescein), Azides, Fluorescence polarization, Microscopy
货号 规格 价格 货期
14130 100 uL, 10 mM/DMSO 80.00$ in stock
34130 500 uL, 10 mM/DMSO 100.00$ in stock
44130 1 mL, 10 mM/DMSO 150.00$ in stock
A4130 1 mg 80.00$ in stock
B4130 5 mg 100.00$ in stock
C4130 10 mg 150.00$ in stock
D4130 25 mg 295.00$ in stock
E4130 50 mg 450.00$ in stock
F4130 100 mg 780.00$ in stock

FAM azide for Click chemistry labeling. FAM remains one of the most popular fluorescent labels for various applications. Most instruments capable of fluorescence detection, ranging from plate readers to fluorescence microscopes, are able to work in FAM channel.

With versatility of Click chemistry and this reagent, it is possible to attach this popular fluorophore to nearly any alkyne bearing molecule.

FAM azide is available both as solid compound, and as 10 mM solution in DMSO ready to use in our recommended labeling protocol. This product is a pure 5-isomer. FAM is a replacement for DyLight 488.

用于点击化学标记的 FAM 叠氮化物。 FAM 仍然是各种应用中最受欢迎的荧光标记之一。 大多数能够进行荧光检测的仪器,从读板器到荧光显微镜,都能够在 FAM 通道中工作。

借助 Click 化学和该试剂的多功能性,可以将这种流行的荧光团连接到几乎任何带有炔烃的分子上。

FAM 叠氮化物既可作为固体化合物使用,也可作为 10 mM DMSO 溶液提供,可用于我们推荐的标记方案。 本品为纯5-异构体。 FAM 是 DyLight 488 的替代品。

FAM azide, 5-isomer,FAM 叠氮化物,5-isomer相关产品

BDP TMR NHS ester

Amine reactive NHS ester of BDP TMR, bright borondipyrromethene dye for TAMRA channel especially suitable for fluorescence polarization assays.

BDP TMR 的胺活性 NHS 酯,用于 TAMRA 通道的明亮硼二吡咯亚甲基染料,特别适用于荧光偏振测定。

HEX azide, 6-isomer

Azide of green-yellow emitting HEX dye is used for conjugation with oligonucleotides via [3+2]-dipolar cycloaddition.

绿黄色发射 HEX 染料的叠氮化物用于通过 [3+2]-偶极环加成与寡核苷酸缀合。

BDP TR azide

BDP TR is a red emitting fluorophore for ROX channel. This is an azide for copper catalyzed and copper free Click chemistry conjugation.

BDP TR 是一种用于 ROX 通道的红色发射荧光团。 这是一种用于铜催化和无铜点击化学偶联的叠氮化物。

General properties

Appearance: yellowish crystals 淡黄色晶体
Molecular weight: 458.42
CAS number: 510758-23-3
Molecular formula: C24H18N4O6
Solubility: soluble in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存:收到后 24 个月,在 -20°C 避光保存。 运输:在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。

MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

相关文献:

  1. Haider, N.; Dutt, P.; van de Kooij, B.; Yaffe, M.B.; Stambolic, V. NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity. bioRxiv, preprint. doi: 10.1101/516971
  2. Gueiderikh, A.; Maczkowiak-Chartois, F.; Rouvet, G.; Souquère-Besse, S.; Apcher, S.; Diaz, J.-J.; Rosselli, F. Fanconi anemia A protein participates in nucleolar homeostasis maintenance and ribosome biogenesis. Science Advances, 2021, 7(1), eabb5414. doi: 10.1126/sciadv.abb5414
  3. Ramey-Ward, A.N.; Su, H.; Salaita, K. Mechanical stimulation of adhesion receptors using light-responsive nanoparticle actuators enhances myogenesis. ACS Applied Materials & Interfaces, 2020, 12(32), 35903–35917. doi: 10.1021/acsami.0c08871
  4. Kim, D.; Singh, N.; Waldemer-Streyer, R.J.; Yoon, M.-S.; Chen, J. Muscle-derived TRAIL negatively regulates myogenic differentiation. Experimental Cell Research, 2020, 394(1), 112165. doi: 10.1016/j.yexcr.2020.112165