标签： FCGR2B Human

CD32, CD32B, FCG2, FCGR2, IGFR2, Low affinity immunoglobulin gamma Fc region receptor II-b, CDw32, Fc-gamma-RIIb, FcRII-b.

FCGR2B is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. FCGR2B participates in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. FCGR2B Expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, Langerhans cells, B-cells, platelets cells and placenta . Variants in FCGR2B may increase susceptibilty to systemic lupus erythematosus .

FCGR2B 是免疫球蛋白 γ 复合物 Fc 区的低亲和力受体。 FCGR2B 参与免疫复合物的吞噬作用和 B 细胞产生抗体的调节。 FCGR2B 在单核细胞、中性粒细胞、巨噬细胞、嗜碱性粒细胞、嗜酸性粒细胞、朗格汉斯细胞、B 细胞、血小板细胞和胎盘中表达。 FCGR2B 的变异体可能会增加对系统性红斑狼疮的易感性。

FCGR2B Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 197 amino acids and having a molecular mass of 22.0kDa. FCGR2Bis fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

在大肠杆菌中产生的 FCGR2B Human Recombinant 是一条单一的、非糖基化的多肽链，包含 197 个氨基酸，分子量为 22.0kDa。 FCGR2Bis 在 N 末端与 25 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。

Escherichia Coli.

Sterile Filtered clear solution.

FCGR2B protein solution contains 20mM Tris-HCl buffer , 0.15M NaCl, 30% glycerol and 1mM DTT.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.

Greater than 95.0% as determined by -PAGE.

MGSSHHHHHH SSGLVPRGSH MGSHMAPPKA VLKLEPQWIN VLQEDSVTLT CRGTHSPESD SIQWFHNGNL IPTHTQPSYR FKANNNDSGE YTCQTGQTSL SDPVHLTVLS EWLVLQTPHL EFQEGETIVL RCHSWKDKPL VKVTFFQNGK SKKFSRSDPN FSIPQANHSH SGDYHCTGNI GYTLYSSKPV TITVQAP.

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