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FCGR2A Human
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CD32a Human Recombinant
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PRO-029
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Catalogue number
PRO-029
Synonyms
CD32, CD32A, CDw32, FcGR, IGFR2, MGC23887, MGC30032, Low affinity immunoglobulin gamma Fc region receptor II-a, IgG Fc receptor II-a, Fc-gamma-RIIa, FcRII-a, FCG2, FCGR2A1.
Introduction
CD32a, also known as FCGR2A, belongs to a family of immunoglobulin Fc receptor genes located on the surface of various immune response cells. FCGR2A which is a cell surface receptor found on phagocytic cells like macrophages and neutrophils, takes part in the process of phagocytosis and clearing of immune complexes. FCGR2A initiates cellular responses against pathogens and soluble antigens by binding to IgG. FCGR2A, which is a low affinity receptor, binds to the Fc region of immunoglobulins gamma.
CD32a，又称FCGR2A，属于免疫球蛋白Fc受体基因家族，位于各种免疫反应细胞表面。 FCGR2A 是一种在巨噬细胞和中性粒细胞等吞噬细胞上发现的细胞表面受体，参与吞噬和清除免疫复合物的过程。 FCGR2A 通过与 IgG 结合启动针对病原体和可溶性抗原的细胞反应。 FCGR2A 是一种低亲和力受体，与免疫球蛋白 γ 的 Fc 区结合。
Description
FCGR2A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 208 amino acids and having a molecular mass of 23.0kDa. FCGR2A is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
在大肠杆菌中产生的 FCGR2A 人重组体是一条单一的、非糖基化的多肽链，包含 208 个氨基酸，分子量为 23.0kDa。 FCGR2A 在 N 端与 25 个氨基酸的 His-tag 融合，并通过专有色谱技术进行纯化。
Source
E.coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
FCGR2A protein solution containing 20mM Tris-HCl buffer , 0.1M NaCl, 50% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
For long term storage it is recommended to add a carrier protein .
Avoid multiple freeze-thaw cycles.
如果整个小瓶将在 2-4 周内使用，请在 4°C 下储存。 储存，在 -20°C 下冷冻更长时间。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。
对于长期储存，建议添加载体蛋白。
避免多次冻融循环。
Purity
Greater than 90% as determined by -PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSHMQAAPP KAVLKLEPPW INVLQEDSVT LTCQGARSPE IQWFHNG NLIPTHTQPS YRFKANNNDS GEYTCQTGQT SLSDPVHLTV LSEWLVLQTP HLEFQEGETI MLRCHSWKDK PLVKVTFFQN GKSQKFSRLD PTFSIPQANH SHSGDYHCTG NIGYTLFSSK PVTITVQVPS MGSSSPMG.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.