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Eotaxin 2 Rat
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Eotaxin-2 Rat Recombinant
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CHM-282
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Catalogue number
CHM-282
Synonyms
C-C motif chemokine 24, Small-inducible cytokine A24, Myeloid progenitor inhibitory factor 2, CK-beta-6, Eosinophil chemotactic protein 2, Eotaxin-2, CCL24, Ckb-6, MPIF2, MPIF-2, SCYA24, Eotaxin2, CCL-24.
Introduction
Eotaxin-2,也称为 MPIF2 和 Ckb6,是一种由活化的单核细胞和 T 淋巴细胞产生的新型 CC 趋化因子。 Eotaxin-2 选择性地趋化表达 CCR3 的细胞,包括嗜酸性粒细胞、嗜碱性粒细胞、Th2 T 细胞、肥大细胞和某些树突状细胞亚群。 此外,Eotaxin-2 抑制多能造血祖细胞的增殖。 包含 C 末端截短的成熟蛋白质包含 78 个氨基酸。
CCL24 用作静息 t 淋巴细胞和嗜酸性粒细胞的趋化因子。 CCL24 对中性粒细胞具有较低的趋化活性,但对单核细胞和活化的淋巴细胞则没有。 CCL24 是多能造血祖细胞系形成集落的强抑制因子,并与 CCR3 结合。
CCL24 用作静息 t 淋巴细胞和嗜酸性粒细胞的趋化因子。 CCL24 对中性粒细胞具有较低的趋化活性,但对单核细胞和活化的淋巴细胞则没有。 CCL24 是多能造血祖细胞系形成集落的强抑制因子,并与 CCR3 结合。
Description
CCL24 Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 93 amino acids and having a molecular mass of 10.2kDa.
The CCL24 is purified by proprietary chromatographic techniques.
The CCL24 is purified by proprietary chromatographic techniques.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized powder.
Formulation
Lyophilized from a 0.2µm filtered concentrated solution in 1×PBS, pH 7.4.
Solubility
It is recommended to reconstitute the lyophilized CCL24 Rat Recombinant in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability
Lyophilized Eotaxin-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL24 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.
Please prevent freeze-thaw cycles.
Purity
Greater than 97.0% as determined by:
Analysis by RP-HPLC.
Analysis by -PAGE.
Analysis by RP-HPLC.
Analysis by -PAGE.
Amino acid sequence
VTIPSSCCVT FISKKIPVNR VISYQLANGS ICPKAGVIFI TKKGHKICTD PKLPWVQKHI KNLDAKRNQP SEGAKALGPK FVIQKLRGNS TKV.
Biological Activity
Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10-100ng/ml corresponding to a Specific Activity of 10,000-100,000IU/mg.
Usage
ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Related Products
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Eotaxin 2 Human
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Eotaxin 2 Mouse