标签： Eotaxin-2 人重组体

C-C motif chemokine 24, Small-inducible cytokine A24, Myeloid progenitor inhibitory factor 2, CK-beta-6, Eosinophil chemotactic protein 2, Eotaxin-2, CCL24, Ckb-6, MPIF2, MPIF-2, SCYA24, Eotaxin2, CCL-24.

Eotaxin-2，也称为 MPIF2 和 Ckb6，是一种由活化的单核细胞和 T 淋巴细胞产生的新型 CC 趋化因子。 Eotaxin-2 选择性地趋化表达 CCR3 的细胞，包括嗜酸性粒细胞、嗜碱性粒细胞、Th2 T 细胞、肥大细胞和某些树突状细胞亚群。 此外，Eotaxin-2 抑制多能造血祖细胞的增殖。 包含 C 末端截短的成熟蛋白质包含 78 个氨基酸。
CCL24 用作静息 t 淋巴细胞和嗜酸性粒细胞的趋化因子。 CCL24 对中性粒细胞具有较低的趋化活性，但对单核细胞和活化的淋巴细胞则没有。 CCL24 是多能造血祖细胞系形成集落的强抑制因子，并与 CCR3 结合。

CCL24 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 78 amino acids and having a molecular mass of 8.8 kDa.
The CCL24 is purified by proprietary chromatographic techniques.

Escherichia Coli.

Sterile Filtered White lyophilized powder.

The CCL24 protein was lyophilized from a concentrated sterile solution containing 20mM PBS pH-7.4 and 0.15M sodium chloride.

It is recommended to reconstitute the lyophilized CCL24 Human Recombinant in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Lyophilized Eotaxin-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL24 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein .
Please prevent freeze-thaw cycles.

Greater than 97.0% as determined by Analysis by RP-HPLC.
Analysis by -PAGE.

VVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKGGVIFTTKKGQQFCG
DPKQEWV QRYMKNLDAKQKKASPRARAVA.

The activity is determined by the chemoattract of human PBE at a concentration between 50-100 ng/ml corresponding to a Specific Activity of 10,000-20,000IU/mg.

ProSpec’s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.