标签： Cycloalkyne

DBCO STP ester

DBCO STP ester,二苯并环辛炔磺基四氟苯酯（DBCO STP 酯）是一种水溶性试剂，可用于修饰含有 -NH2 基团的肽、抗体、蛋白质和其他分子。

  • Products
  • Click chemistry
  • Non-fluorescent alkynes
  • DBCO STP ester

DBCO STP ester

标签：Cycloalkyne,Non-fluorescent alkynes,Click chemistry
货号 规格 价格 货期
2584-5mg 5 mg – 10 days
2584-10mg 10 mg 90.00$ in stock
2584-25mg 25 mg 180.00$ in stock
2584-100mg 100 mg 450.00$ in stock
2584-500mg 500 mg 1700.00$ in stock
2584-1g 1 g 3000.00$ in stock
2584-5g 5 g please inquire 21 days

 

Dibenzocyclooctyne sulfotetrafluorophenyl ester (DBCO STP ester) is a water-soluble reagent that can be used for the modification of peptides, antibodies, proteins, and other molecules containing the -NH2 group.

STP esters are hydrolyzed much more slowly than NHS esters, thus allowing efficient biomolecule modification in the aqueous medium.

The dibenzocyclooctyne (DBCO) moiety, which is also known as ADIBO or DIBAC, is the most common substrate for copper-free Click Chemistry reactions that are promoted by ring strain. In this reaction in the presence of a Cu(I) catalyst, DBCO derivatives react with biomolecules functionalized by the azide group to result in stable triazoles.

二苯并环辛炔磺基四氟苯酯（DBCO STP 酯）是一种水溶性试剂，可用于修饰含有 -NH2 基团的肽、抗体、蛋白质和其他分子。

STP 酯的水解速度比 NHS 酯慢得多，因此可以在水性介质中进行有效的生物分子修饰。

二苯并环辛炔 (DBCO) 部分，也称为 ADIBO 或 DIBAC，是由环应变促进的无铜点击化学反应的最常见底物。 在该反应中，在 Cu(I) 催化剂的存在下，DBCO 衍生物与被叠氮基官能化的生物分子反应生成稳定的三唑。

DBCO STP ester相关产品

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

Hexynoic acid STP ester

Alkyne activated ester for the modification of amine groups. STP ester group is an excellent alternative to NHS ester functionality.

用于修饰胺基的炔烃活化酯。 STP 酯基是 NHS 酯官能团的绝佳替代品。

Pentynoic acid STP ester

An activated ester for the introduction of alkyne into peptides/proteins.

用于将炔烃引入肽/蛋白质的活化酯。

General properties

Appearance: beige powder
Molecular weight: 569.46
Molecular formula: C26H16NF4O6Sa
Solubility: good in water, DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.
MSDS: Download
Product specifications

DBCO NHS ester

DBCO NHS ester,二苯并环辛炔 (ADIBO, DBCO) 是对应变促进炔烃叠氮化物环加成 (spAAC) 反应性最强的环炔烃之一 – 一种无铜点击化学反应。

  • Products
  • Click chemistry
  • Non-fluorescent alkynes
  • DBCO NHS ester

DBCO NHS ester

标签：NHS esters, Alkynes, Copper free Click chemistry, Cycloalkyne, Protein labeling, Cross linking reagents
货号 规格 价格 货期
34720 10 mg 60.00$ in stock
44720 25 mg 95.00$ in stock
54720 50 mg 145.00$ in stock
64720 100 mg 210.00$ in stock
94720 1 g 1190.00$ in stock
K4720 5 g 3570.00$ in stock
N4720 25 g please inquire 21 days

Dibenzocyclooctyne (ADIBO, DBCO) is one of the most reactive cycloalkynes for strain promoted alkyne azide cycloaddition (spAAC) – a copper free Click chemistry reaction.

This is an amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.

DBCO reacts instantly with azides. The rate of the reaction is much higher than that of copper-catalyzed reaction, and reactions with many other cyclooctynes. Unlike some other cyclooctynes, DBCO does not react with tetrazines – this allows to carry out orthogonal conjugation of azides with DBCO, and trans-cyclooctenes with tetrazines.

二苯并环辛炔 (ADIBO, DBCO) 是对应变促进炔烃叠氮化物环加成 (spAAC) 反应性最强的环炔烃之一 – 一种无铜点击化学反应。

这是一种胺反应性 NHS 酯，可将反应性部分轻松连接到几乎任何伯胺或仲胺基团，例如蛋白质、肽或小分子胺的基团。

DBCO 立即与叠氮化物发生反应。 该反应的速率远高于铜催化的反应，以及与许多其他环辛炔的反应。 与其他一些环辛炔不同，DBCO 不与四嗪反应 – 这允许叠氮化物与 DBCO 以及反式环辛烯与四嗪的正交共轭。

DBCO NHS ester相关产品

FAM azide, 6-isomer

FAM (fluorescein) azide, 6-isomer is a commonly used fluorescent dye azide for Click Chemistry.

FAM（荧光素）叠氮化物，6 异构体是 Click Chemistry 中常用的荧光染料叠氮化物。

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cy5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

General properties

Appearance: off white solid
Mass spec M+ increment: 315.1
Molecular weight: 430.45
CAS number: 1384870-47-6
Molecular formula: C25H22N2O5
IUPAC name: 6-{2-Azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-6-oxohexanamide
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

相关文献：

  1. Adams, M.R.; Moody, C.T.; Sollinger, J.L.; Brudno, Y. Extracellular Matrix-Anchored Click Motifs for Specific Tissue Targeting. Molecular Pharmaceutics, 2020, 17(2), 392–403. doi: 10.1021/acs.molpharmaceut.9b00589
  2. Alshanski, I.; Blaszkiewicz, J.; Mervinetsky, E.; Rademann, J.; Yitzchaik, S.; Hurevich, M. Sulfation Patterns of Saccharides and Heavy Metal Ions Binding. Chemistry, 2019, 25(52), 12083–12090. doi: 10.1002/chem.201901538
  3. Andersen, V.L.; Vinther, M.; Kumar, R.; Ries, A.; Wengel, J.; Nielsen, J.S.; Kjems, J. A self-assembled, modular nucleic acid-based nanoscaffold for multivalent theranostic medicine. Theranostics, 2019, 9(9), 2662–2677. doi: 10.7150/thno.32060

sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 DBCO,Sulfo-Cy5.5 是一种具有接近 NIR 范围的远红发射的染料。 它已在非侵入性活体成像中得到应用。 这种特殊的磺基-Cy5.5 衍生物，即 DBCO（或 ADIBO）衍生物，含有环炔烃，用于无铜共轭这种荧光团与各种有机叠氮化物。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 DBCO

标签：Copper free Click chemistry, Cycloalkyne, sulfo-Cy5.5
货号 规格 价格 货期
173F0 1 mg 110.00$ in stock
273F0 5 mg 290.00$ in stock
473F0 25 mg 690.00$ in stock
573F0 50 mg 1270.00$ in stock
673F0 100 mg 1990.00$ in stock

Sulfo-Cyanine5.5 is a dye with far-red emission approaching NIR range. It has found application in non-invasive live-organism imaging. This particular derivative of sulfo-Cyanine5.5, the DBCO (or ADIBO) derivative, contains cycloalkyne for copper-free conjugation of this fluorophore with various organic azides.

The reaction between DBCO and azides is blazingly fast, orders of magnitude exceeding the rate of copper-catalyzed reaction between azides and terminal alkynes. It is also catalyst-free.

This reagent can be used to conjugate sulfo-Cyanine5.5 dye to a variety of azide-labeled molecules.

Sulfo-Cy5.5 是一种具有接近 NIR 范围的远红发射的染料。 它已在非侵入性活体成像中得到应用。 这种特殊的磺基-Cyanine5.5 衍生物，即 DBCO（或 ADIBO）衍生物，含有环炔烃，用于无铜共轭这种荧光团与各种有机叠氮化物。

DBCO 和叠氮化物之间的反应非常快，数量级超过了铜催化的叠氮化物和末端炔烃之间的反应速率。 它也不含催化剂。

该试剂可用于将磺基-Cyanine5.5 染料与多种叠氮化物标记的分子结合。

Absorption and emission spectra of sulfo-Cyanine5.5

sulfo-Cyanine5.5 DBCO

sulfo-Cyanine5.5 DBCO相关产品

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物，用于与反式环辛烯和其他应变烯烃的 TCO 连接。

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

Biotin-PEG3-Azide

Biotin azide is a reagent for click chemistry labeling with biotin, a well-known affinity probe.

Biotin azide 是一种用生物素（一种众所周知的亲和探针）进行点击化学标记的试剂。

General properties

Appearance: dark blue solid
Molecular weight: 1317.69
Molecular formula: C61H59N4K3O14S4
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 673
ε, L⋅mol−1⋅cm−1: 211000
Emission maximum, nm: 691
Fluorescence quantum yield: 0.21
CF260: 0.09
CF280: 0.11

sulfo-Cyanine5 DBCO

sulfo-Cyanine5 DBCO,Copper free Click chemistry reaction between strained cycloalkynes (cyclooctynes), and azides, is a very fast and robust reaction. It can be used for a fast labeling with fluorescent dyes. This reagent is a derivative of water soluble sulfo-Cyanine5 dye which emits in red channel. It is useful for the labeling of biomolecules in aqueous media.

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • sulfo-Cyanine5 DBCO

sulfo-Cyanine5 DBCO

标签：sulfo-Cy5, Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
133F0 1 mg 110.00$ in stock
233F0 5 mg 290.00$ in stock
433F0 25 mg 690.00$ in stock
533F0 50 mg 1270.00$ in stock
633F0 100 mg 1990.00$ in stock

Copper free Click chemistry reaction between strained cycloalkynes (cyclooctynes), and azides, is a very fast and robust reaction. It can be used for a fast labeling with fluorescent dyes. This reagent is a derivative of water soluble sulfo-Cyanine5 dye which emits in red channel. It is useful for the labeling of biomolecules in aqueous media.

紧张的环炔烃（环辛炔）和叠氮化物之间的无铜点击化学反应是一种非常快速且稳定的反应。 它可用于荧光染料的快速标记。 该试剂是水溶性磺基-Cyanine5染料的衍生物，在红色通道中发射。 它可用于标记水性介质中的生物分子。

Absorption and emission spectra of sulfo-Cyanine5

sulfo-Cyanine5 DBCO

sulfo-Cyanine5 DBCO相关产品

TMRE, Tetramethylrhodamine ethyl ester, perchlorate

Orange-red fluorescent dye for staining active mitochondria and quantitate mitochondrial membrane potential in live cells.

橙红色荧光染料，用于染色活性线粒体和定量活细胞中的线粒体膜电位。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

Cyanine5.5 amine

Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.

Cy5.5 的氨基衍生物，一种发射远红色荧光的花青染料。

General properties

Appearance: dark colored solid
Molecular weight: 981.27
Molecular formula: C53H57N4KO8S2
Solubility: good in water, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 271000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.28
CF260: 0.04
CF280: 0.04

相关产品

  1. Mamot, A.; Sikorski, P.J.; Siekierska, A.; de Witte, P.; Kowalska, J.; Jemielity, J. Ethylenediamine derivatives efficiently react with oxidized RNA 3′ ends providing access to mono and dually labelled RNA probes for enzymatic assays and in vivo translation. Nucleic Acids Research, 2022, 50(1), e3. doi: 10.1093/nar/gkab867
  2. Lim, S.; Kim, W.; Song, S.; Shim, M.K.; Yoon, H.Y.; Kim, B.-S.; Kwon, I.C.; Kim, K. Intracellular Uptake Mechanism of Bioorthogonally Conjugated Nanoparticles on Metabolically Engineered Mesenchymal Stem Cells. Bioconjugate Chemistry, 2021, 32(1), 199–214. doi: 10.1021/acs.bioconjchem.0c00640
  3. Desai, B.J.; Gonzalez, R.L. Multiplexed genomic encoding of non-canonical amino acids for labeling large complexes. Nature Chemical Biology, 2020, 16, 1129–1135. doi: 10.1038/s41589-020-0599-5

sulfo-Cyanine3 DBCO

sulfo-Cyanine3 DBCO,储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。Sulfo-Cyanine3 DBCO 是一种具有环炔基团的水溶性荧光染料，用于无铜点击化学。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • sulfo-Cyanine3 DBCO

sulfo-Cyanine3 DBCO

标签：Copper free Click chemistry, Cycloalkyne, sulfo-Cyanine3
货号 规格 价格 货期
113F0 1 mg 110.00$ in stock
213F0 5 mg 290.00$ in stock
413F0 25 mg 690.00$ in stock
513F0 50 mg 1270.00$ in stock
613F0 100 mg 1990.00$ in stock

Sulfo-Cyanine3 DBCO is a water soluble fluorescent dye with cycloalkyne group for copper free Click chemistry.

DBCO (dibenzocyclooctyne) is a cyclooctyne with very high reactivity towards azides, still possessing good stability.

Sulfo-Cyanine3 DBCO 是一种具有环炔基团的水溶性荧光染料，用于无铜点击化学。

DBCO（二苯并环辛炔）是一种环辛炔，对叠氮化物具有非常高的反应性，但仍具有良好的稳定性。

Absorption and emission spectra of sulfo-Cyanine3

sulfo-Cyanine3 DBCO

sulfo-Cyanine3 DBCO相关产品

Sulfo-Cyanine3 azide

Water-soluble sulfo-Cyanine3 dye azide for Click Chemistry.

用于 Click Chemistry 的水溶性磺基-Cy3 染料叠氮化物。

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

Sulfo-Cyanine5.5 NHS ester

Water soluble, sulfonated, far-red sulfo-Cyanine5.5 dye in the form of NHS ester.

NHS 酯形式的水溶性磺化远红色磺基-Cy5.5 染料。

General properties

Appearance: red solid 红色固体
Mass spec M+ increment: 916.4
Molecular weight: 955.23
Molecular formula: C51H55N4KO8S2
Solubility: soluble in water (0.11 M = 11 g/L), DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

相关产品

  1. Tugel, U.; Casas, M.G.; Wiltschi, B. Site-Specific Incorporation of Non-canonical Amino Acids by Amber Stop Codon Suppression in Escherichia coli. Peptide and Protein Engineering (Springer Protocols Handbooks), 2020, 267–281. doi: 10.1007/978-1-0716-0720-6_14
  2. Desai, B.J.; Gonzalez, R.L. Multiplexed genomic encoding of non-canonical amino acids for labeling large complexes. Nature Chemical Biology, 2020, 16, 1129–1135. doi: 10.1038/s41589-020-0599-5

ROX DBCO, 5-isomer

ROX DBCO, 5-isomer,ROX DBCO 是明亮的罗丹明染料罗丹明 X 和 DBCO（二苯并环辛炔）的共轭物，DBCO（二苯并环辛炔）是一种反应性基团，包含用于与叠氮化物共轭的应变炔键。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • ROX DBCO, 5-isomer

ROX DBCO, 5-isomer

标签：ROX (Rhodamine X, Rhodamine 101), Copper free Click chemistry, Cycloalkyne
112F0 1 mg 110.00$ in stock
212F0 5 mg 290.00$ in stock
412F0 25 mg 690.00$ in stock
512F0 50 mg 1270.00$ in stock
612F0 100 mg 1990.00$ in stock

ROX DBCO is a conjugate of bright rhodamine dye rhodamine X, and DBCO (dibenzocyclooctyne) – a reactive group that contains a strained alkyne bond for the conjugation with azides.

This reagent is useful for the labeling of various azides with ROX dye.

This derivative contains pure 5-isomer of ROX.

ROX DBCO 是明亮的罗丹明染料罗丹明 X 和 DBCO（二苯并环辛炔）的共轭物，DBCO（二苯并环辛炔）是一种反应性基团，包含用于与叠氮化物共轭的应变炔键。

该试剂可用于用 ROX 染料标记各种叠氮化物。

该衍生物含有纯的 ROX 5-异构体。

Absorption and emission spectra of ROX

ROX DBCO, 5-isomer

ROX DBCO, 5-isomer相关产品

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

水溶性 NIR 染料胺，Cyanine7 染料的磺化衍生物，用于通过酶促氨基转移进行修饰。

ROX azide, 5- isomer

ROX (aka rhodamine X or rhodamine 101) azide for biomolecule labeling through Click Chemistry.

ROX（又名罗丹明 X 或罗丹明 101）叠氮化物，用于通过 Click Chemistry 进行生物分子标记。

BDP 630/650 tetrazine

BDP 630/650 is a borondipyrromethene dye for Cyanine5 channel. This is a tetrazine derivative for the coupling with strained cycloalkenes.

BDP 630/650 是用于 Cyanine5 通道的硼二吡咯亚甲基染料。 这是一种用于与应变环烯烃偶联的四嗪衍生物。

General properties

Appearance: red solid 红色固体
Mass spec M+ increment: 834.4
Molecular weight: 835.00
Molecular formula: C54H50N4O5
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 570
ε, L⋅mol−1⋅cm−1: 93000
Emission maximum, nm: 591
Fluorescence quantum yield: 1.00

FAM DBCO, 6-isomer

FAM DBCO, 6-isomer,荧光素 (FAM) 是最古老但众所周知的荧光染料之一。 FAM 的这种衍生物含有环辛炔基团（二苯并环辛炔，缩写为 DBCO 或 ADIBO），用于通过无铜、应变促进的叠氮化物炔烃环加成 (spAAc) 与叠氮化物结合。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • FAM DBCO, 6-isomer

FAM DBCO, 6-isomer

标签：FAM (Fluorescein), Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
151F0 1 mg 110.00$ in stock
251F0 5 mg 210.00$ in stock
451F0 25 mg 160.00$ in stock
551F0 50 mg 270.00$ in stock
651F0 100 mg 420.00$ in stock
Fluorescein (FAM) is one of the oldest yet well known fluorescent dyes. This derivative of FAM contains cyclooctyne group (dibenzocyclooctyne, abbreviated as DBCO or ADIBO) for the conjugation with azides via copper-free, strain-promoted azide alkyne cycloaddition (spAAc).

FAM DBCO can be used for the labeling of proteins, peptides, nucleic acids, and other molecules containing azide groups. Azides react with DBCO spontaneously upon simple mixing. The reaction does not require any catalysts, and it is very efficient.

Fluorescein can be detected using a variety of different instruments.

荧光素 (FAM) 是最古老但众所周知的荧光染料之一。 FAM 的这种衍生物含有环辛炔基团（二苯并环辛炔，缩写为 DBCO 或 ADIBO），用于通过无铜、应变促进的叠氮化物炔烃环加成 (spAAc) 与叠氮化物结合。

FAM DBCO 可用于标记蛋白质、肽、核酸和其他含有叠氮基的分子。 叠氮化物在简单混合后会与 DBCO 自发反应。 该反应不需要任何催化剂，而且非常有效。

可以使用多种不同的仪器检测荧光素。

FAM DBCO, 6-isomer相关产品

Cyanine7 DBCO

NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.

用环辛炔部分功能化的 NIR 荧光染料，用于与叠氮化物的无铜点击化学缀合。

BDP FL amine

Amino derivative of BDP FL dye, borondipyrromethene dye for FAM (fluorescein) 488 nm channel.

BDP FL 染料的氨基衍生物，用于 FAM（荧光素）488 nm 通道的硼二吡咯亚甲基染料。

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

General properties

Appearance: orange solid 橙色固体
Molecular weight: 676.71
Molecular formula: C42H32N2O7
Solubility: good in DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 494
ε, L⋅mol−1⋅cm−1: 75000
Emission maximum, nm: 520
Fluorescence quantum yield: 0.9
CF260: 0.20
CF280: 0.17

Cyanine7 DBCO

Cyanine7 DBCO,Cy7 DBCO 是一种具有环炔部分的 NIR 荧光染料，用于通过无铜、应变促进的炔烃叠氮化物环加成 (spAAC) 与叠氮化物结合。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • Cyanine7 DBCO

Cyanine7 DBCO

标签：Cyanine7, Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
A50F0 1 mg 110.00$ in stock
B50F0 5 mg 210.00$ in stock
C50F0 10 mg 310.00$ in stock
D50F0 25 mg 410.00$ in stock
E50F0 50 mg 695.00$ in stock
F50F0 100 mg 1190.00$ in stock

Cyanine7 DBCO is a NIR fluorescent dye with cycloalkyne moiety for the conjugation with azides by means of copper-free, strain promoted alkyne azide cycloaddition (spAAC).

Azodibenzocyclooctyne (DBCO or ADIBO) fragment is a stable but active cycloalkyne that reacts very rapidly with azides.

Cy7 DBCO 是一种具有环炔部分的 NIR 荧光染料，用于通过无铜、应变促进的炔烃叠氮化物环加成 (spAAC) 与叠氮化物结合。

偶氮二苯并环辛炔（DBCO 或 ADIBO）片段是一种稳定但具有活性的环炔烃，可与叠氮化物快速反应。

Absorption and emission spectra of Cyanine7 fluorophore

Cyanine7 DBCO

Cyanine7 DBCO相关产品

BDP 630/650 maleimide

BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.

BDP 630/650 马来酰亚胺是一种硫醇反应性、基于硼二吡咯亚甲基的染料，经过调整以匹配 Cy5 荧光团的远红通道。

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cy5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

EdU (5-ethynyl-2′-deoxyuridine)

EdU is a nucleoside which is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by Click chemistry reaction with fluorescent dye azides to reveal cell proliferation.

EdU 是一种核苷，可通过细胞酶掺入复制的 DNA 中。 之后，细胞中所含的 DNA 可以通过与荧光染料叠氮化物的 Click 化学反应进行显色，以揭示细胞增殖情况。

General properties

Appearance: dark green solid 深绿色固体
Mass spec M+ increment: 849.5
Molecular weight: 885.62
CAS number: 2692677-77-1
Molecular formula: C58H65N4ClO2
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  2. Alberg, I.; Kramer, S.; Schinnerer, M.; Hu, Q.; Seidl, C.; Leps, C.; Drude, N.; Möckel, D.; Rijcken, C.; Lammers, T.; Diken, M.; Maskos, M.; Morsbach, S.; Landfester, K.; Tenzer, S.; Barz, M.; Zentel, R. Polymeric Nanoparticles with Neglectable Protein Corona. Small, 2020, 16(18), 1907574. doi: 10.1002/smll.201907574

Cyanine5.5 DBCO

Cyanine5.5 DBCO,应变环炔烃和叠氮化物之间的应变促进炔烃叠氮化物环加成 (spAAc) 是一种有用的生物共轭方法，它消除了对经典 CuAAc Click 化学所需的铜催化剂的需求。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • Cyanine5.5 DBCO

Cyanine5.5 DBCO

标签：Cy5.5, Cycloalkyne
货号 规格 价格 货期
A70F0 1 mg 110.00$ in stock
B70F0 5 mg 210.00$ in stock
C70F0 10 mg 310.00$ in stock
D70F0 25 mg 410.00$ in stock
E70F0 50 mg 695.00$ in stock
F70F0 100 mg 1190.00$ in stock

Strain promoted alkyne azide cycloaddition (spAAc) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAc Click chemistry.

Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.

Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.

应变环炔烃和叠氮化物之间的应变促进炔烃叠氮化物环加成 (spAAc) 是一种有用的生物共轭方法，它消除了对经典 CuAAc Click 化学所需的铜催化剂的需求。

Cyanine5.5 DBCO 是一种含有 Cyanine5.5 荧光染料的环辛炔产品。 这种荧光团用于生物成像、生物分布研究和显微镜检查。

Cyanine5.5 DBCO 可用于将荧光团与各种叠氮化物结合。

Absorption and emission spectra of Cyanine5.5

Cyanine5.5 DBCO

Cyanine5.5 DBCO相关产品

Sulfo-Cyanine5 maleimide

Thiol reactive, water soluble cyanine dye for Cy5® channel.

用于 Cy5® 的硫醇活性水溶性花青染料 渠道。

Biotin alkyne

Biotin alkyne is a reactive affinity label which can be attached to biomolecules via Click Chemistry.

生物素炔烃是一种反应性亲和标记，可以通过点击化学连接到生物分子上。

dsGreen Gel Staining Solution, 10000×

dsGreen for staining dsDNA in gels.

dsGreen 用于在凝胶中染色 dsDNA。

General properties

Appearance: dark colored solid 深色固体
Mass spec M+ increment: 882.5
Molecular weight: 1029.14
CAS number: 2643308-61-4
Molecular formula: C61H63N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 684
ε, L⋅mol−1⋅cm−1: 198000
Emission maximum, nm: 710
Fluorescence quantum yield: 0.2
CF260: 0.07
CF280: 0.03

相关文献：

  1. Fornasier, M.; Porcheddu, A.; Casu, A.; Raghavan, S.R.; Jönsson, P.; Schillén, K.; Murgia, S. Surface-modified nanoerythrosomes for potential optical imaging diagnostics. Journal of Colloid and Interface Science, 2021, 582, 246–253. doi: 10.1016/j.jcis.2020.08.032
  2. Lim, Y.G.; Kim, H.J.; Kim, J.W.; Park, K. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry, 2020, 89, 442–447. doi: 10.1016/j.jiec.2020.06.018

Cyanine5 DBCO

Cyanine5 DBCO,一种具有 DBCO（二苯并环辛炔，也称为 ADIBO，偶氮二苯并环辛炔）基团的 Cyanine5 发红光荧光团的衍生物，用于无铜点击化学。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • Cyanine5 DBCO

Cyanine5 DBCO

标签：Cyanine5, Copper free Click chemistry, Cycloalkyne,Cy5
货号 规格 价格 货期
A30F0 1 mg 110.00$ in stock
B30F0 5 mg 210.00$ in stock
C30F0 10 mg 310.00$ in stock
D30F0 25 mg 410.00$ in stock
E30F0 50 mg 695.00$ in stock
F30F0 100 mg 1190.00$ in stock

A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free Click chemistry.

Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain promoted alkyne azide cycloaddition (spAAC). This reaction is very fast, mild, and biocompatible.

Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.

一种具有 DBCO（二苯并环辛炔，也称为 ADIBO，偶氮二苯并环辛炔）基团的 Cyanine5 发红光荧光团的衍生物，用于无铜点击化学。

在不存在铜催化剂的情况下，在应变促进的炔烃叠氮化物环加成 (spAAC) 中，应变的环炔烃，例如环辛炔，与叠氮化物反应非常迅速。 该反应非常快速、温和且具有生物相容性。

与其他环炔烃相比，DBCO 提供了最快的反应动力学，但仍具有良好的稳定性。

Absorption and emission spectra of Cyanine5

Cyanine5 DBCO

Cyanine5 DBCO相关产品

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cyanine7.5的胺反应性NHS酯。

Cyanine5.5 amine

Amino derivative of Cyanine5.5, a far red emitting fluorescent cyanine dye.

Cyanine5.5 的氨基衍生物，一种发射远红色荧光的花青染料。

Sulfo-Cyanine5 tetrazine

Water soluble Cyanine dye tetrazine derivative for TCO ligation with trans-cyclooctenes and other strained olefines.

水溶性花青染料四嗪衍生物，用于与反式环辛烯和其他应变烯烃的 TCO 连接。

General properties

Appearance: dark blue solid 深蓝色固体
Mass spec M+ increment: 928.4
Molecular weight: 929.03
Molecular formula: C53H59N4F6O2P
Solubility: good in DMF, DMSO, chlorinated organic solvents, practically insoluble in water (<1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 646
ε, L⋅mol−1⋅cm−1: 250000
Emission maximum, nm: 662
Fluorescence quantum yield: 0.2
CF260: 0.03
CF280: 0.04

相关文献：

  1. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  2. Qiu, C.-X.; Bai, X.-F.; Shen, Y.; Zhou, Z.; Pan, L.-Q.; Xu, Y.-C.; Zhao, W.-B.; Chen, S.-Q. Specific Inhibition of Tumor Growth by T Cell Receptor-Drug Conjugates Targeting Intracellular Cancer-Testis Antigen NY-ESO-1/LAGE-1. Bioconjugate Chemistry, 2020, 31(12), 2767–2778. doi: 10.1021/acs.bioconjchem.0c00548
  3. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  4. Liu, W.; Zhao, W.; Bai, X.; Jin, S.; Li, Y.; Qiu, C.; Pan, L.; Ding, D.; Xu, Y.; Zhou, Z.; Chen, S. High antitumor activity of Sortase A-generated anti-CD20 antibody fragment drug conjugates. European Journal of Pharmaceutical Sciences, 2019, 134, 81–92. doi: 10.1016/j.ejps.2019.04.015
Cy® is a trademark of GE Healthcare.

Cyanine3.5 DBCO

Cyanine3.5 DBCO,Cy3.5 是一种明亮且光稳定的荧光团，其光谱特性与 Cy3.5™ 染料相似。 Cyanine3.5 DBCO 荧光最大值在 604 nm 处，在橙红色光谱范围内。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • Cyanine3.5 DBCO

Cyanine3.5 DBCO

标签：Cyanine3.5, Cycloalkyne,Cy3.5
货号 规格 价格 货期
A20F0 1 mg 110.00$ in stock
B20F0 5 mg 210.00$ in stock
C20F0 10 mg 310.00$ in stock
D20F0 25 mg 410.00$ in stock
E20F0 50 mg 695.00$ in stock
F20F0 100 mg 1190.00$ in stock

Cyanine3.5 is a bright and photostable fluorophore, which is similar in its spectral characteristics to Cy3.5™ dye. Cyanine3.5 DBCO fluorescence maximum is at 604 nm and in the orange-red spectrum range.

Cyanine3.5 fluorescence is pH insensitive in the range from 4 to 10 and can be detected in the spectrum range with a low level of autofluorescence of biological samples.

Cyanine3.5 DBCO (dibenzocyclooctyne) easily forms conjugates with azide derivatives of biomolecules in copper-free Click Chemistry. The process runs without catalysts or increased temperature, resulting in stable triazoles.

Conjugates of biomolecules with Cyanine3.5 can be used for various microscopy assays, including FRET-microscopy, and in proteomics.

Cyanine3.5 是一种明亮且光稳定的荧光团，其光谱特性与 Cy3.5™ 染料相似。 Cyanine3.5 DBCO 荧光最大值在 604 nm 处，在橙红色光谱范围内。

Cyanine3.5 荧光在 4 到 10 的范围内对 pH 不敏感，并且可以在生物样品的低水平自发荧光的光谱范围内检测到。

Cyanine3.5 DBCO（二苯并环辛炔）在无铜点击化学中很容易与生物分子的叠氮化物衍生物形成共轭物。 该过程在没有催化剂或升高温度的情况下运行，从而产生稳定的三唑。

生物分子与 Cyanine3.5 的偶联物可用于各种显微镜分析，包括 FRET 显微镜和蛋白质组学。

Absorption and emission spectra of Cyanine3.5

Cyanine3.5 DBCO

Cyanine3.5 DBCO相关产品

Cyanine5 DBCO

Cyanine5 dye with dibenzocyclooctyne (DBCO) functional group for copper free Click chemistry.

用于无铜点击化学的具有二苯并环辛炔 (DBCO) 官能团的 Cy5 染料。

Cyanine3 DBCO

Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper free Click chemistry.

Cy3 dibenzocyclooctyne (DBCO, or ADIBO) 是一种用于无铜点击化学的环炔烃染料衍生物。

sulfo-Cyanine5.5 DBCO

Sulfo-Cyanine5.5 DBCO is a far-red, water-soluble reagent for copper-free reaction with azides.

Sulfo-Cy5.5 DBCO 是一种远红色的水溶性试剂，用于与叠氮化物的无铜反应。

General properties

Appearance: dark violet solid 深紫色固体
Molecular weight: 944.95
Molecular formula: C59H61N4BF4O2
Solubility: soluble in organic solvents (DMF, DMSO, dichloromethane), insoluble in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 591
ε, L⋅mol−1⋅cm−1: 116000
Emission maximum, nm: 604
Fluorescence quantum yield: 0.35
CF260: 0.29
CF280: 0.22
Cy™ is a registered trademark of Cytiva in some countries.

Cyanine3 DBCO

Cyanine3 DBCO,偶氮二苯并环辛炔（DBCO 或 ADIBO）是一种稳定但非常活泼的环炔烃，适用于无铜点击化学。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • Cyanine3 DBCO

Cyanine3 DBCO

标签：Cy3, Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
A10F0 1 mg 110.00$ in stock
B10F0 5 mg 210.00$ in stock
C10F0 10 mg 310.00$ in stock
D10F0 25 mg 410.00$ 5 days
E10F0 50 mg 695.00$ in stock
F10F0 100 mg 1190.00$ in stock

Azodibenzocyclooctyne (DBCO or ADIBO) is a stable but very reactive cycloalkyne for copper free Click chemistry.

This reagent is a conjugate of DBCO with Cyanine3 fluorophore for the non-catalyzed, strain promoted reaction with azides.

偶氮二苯并环辛炔（DBCO 或 ADIBO）是一种稳定但非常活泼的环炔烃，适用于无铜点击化学。

该试剂是 DBCO 与 Cyanine3 荧光团的结合物，用于与叠氮化物的非催化、应变促进反应。

Absorption and emission spectra of Cyanine3 fluorophore

Cyanine3 DBCO

Cyanine3 DBCO相关产品

Cyanine5 tetrazine

Cyanine5 is a universal red emitting dye with a very high extinction coefficient, and good quantum yield. This tetrazine derivative reacts very quickly with trans-cyclooctenes and cyclopropenes with the formation of stable conjugates.

Cyanine5 是一种通用的红色发光染料，具有非常高的消光系数和良好的量子产率。 这种四嗪衍生物与反式环辛烯和环丙烯反应非常迅速，形成稳定的共轭物。

sulfo-Cyanine3 DBCO

Sulfo-Cyanine3 DBCO is a cycloalkyne derivative of water soluble, general purpose fluorophore sulfo-Cyanine3 for Click Chemistry.

Sulfo-Cyanine3 DBCO 是用于 Click Chemistry 的水溶性通用荧光团 sulfo-Cyanine3 的环炔衍生物。

Cyanine7.5 NHS ester

Amine reactive NHS ester of NIR fluorescent dye Cyanine7.5.

NIR荧光染料Cy7.5的胺反应性NHS酯。

General properties

Appearance: dark red powder 暗红色粉末
Molecular weight: 902.99
CAS number: 2692677-79-3
Molecular formula: C51H57N4O2PF6
Solubility: good in DMF, DMSO, DCM, alcohols, practically insoluble in water (< 1 uM, < 1 mg/L)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 555
ε, L⋅mol−1⋅cm−1: 150000
Emission maximum, nm: 570
Fluorescence quantum yield: 0.31
CF260: 0.04
CF280: 0.09

相关文献：

  1. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Azide-Terminated RAFT Polymers for Biological Applications. Current Protocols in Chemical Biology, 2020, 12(4), e85. doi: 10.1002/cpch.85
  2. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  3. Jiang, Z.; He, H.; Liu, H.; Thayumanavan, S. Cellular Uptake Evaluation of Amphiphilic Polymer Assemblies: Importance of Interplay between Pharmacological and Genetic Approaches. Biomacromolecules, 2019, 20(12), 4407–4418. doi: 10.1021/acs.biomac.9b01073

BDP TR DBCO

BDP TR DBCO,BDP TR 是一种明亮且光稳定的红色荧光染料。 由于其疏水特性，BDP TR 可以很容易地渗透细胞膜，并且是用于染色各种亲脂性化合物的出色荧光团。 这种染料是 BODIPY™ TR 的类似物，其光谱特性与 ROX 相似。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • BDP TR DBCO

BDP TR DBCO

标签：BDP TR, Cycloalkyne
货号 规格 价格 货期
1D4F0 1 mg 110.00$ in stock
2D4F0 5 mg 210.00$ in stock
4D4F0 25 mg 410.00$ in stock
5D4F0 50 mg 695.00$ in stock
6D4F0 100 mg 1190.00$ in stock

BDP TR is a bright and photostable red-fluorescent dye. Because of its hydrophobic properties, BDP TR can readily permeate cell membranes and is an excellent fluorophore for staining various lipophilic compounds. This dye is an analog of BODIPY™ TR and similar to  ROX by its spectral characteristics.

BDP TR has a long excitation lifetime; besides conventional fluorescence microscopy, it can be used in various fluorescence anisotropy assays.

Being an alternative to alkynes, dibenzocyclooctyne (DBCO) readily reacts with azides in copper-free Click Chemistry reactions, which result in BDP TR-biomolecule conjugates.

BDP TR 是一种明亮且光稳定的红色荧光染料。 由于其疏水特性，BDP TR 可以很容易地渗透细胞膜，并且是用于染色各种亲脂性化合物的出色荧光团。 这种染料是 BODIPY™ TR 的类似物，其光谱特性与 ROX 相似。

BDP TR 具有较长的激发寿命； 除了传统的荧光显微镜外，它还可用于各种荧光各向异性测定。

作为炔烃的替代品，二苯并环辛炔 (DBCO) 在无铜点击化学反应中很容易与叠氮化物反应，从而产生 BDP TR-生物分子偶联物。

BDP TR DBCO相关产品

BDP 650/665 DBCO

This red-fluorescent dye contains a substituting group for copper-free Click Chemistry.

这种红色荧光染料含有一个无铜 Click Chemistry 的取代基。

FAM DBCO, 6-isomer

Cyclooctyne derivative of fluorescein (FAM) for copper free Click chemistry reaction with azides. Contains pure 6-isomer of fluorescein.

荧光素 (FAM) 的环辛炔衍生物，用于与叠氮化物的无铜点击化学反应。 含有纯6-异构体的荧光素。

Cyanine5.5 carboxylic acid

Cy5.5 unactivated free acid cyanine dye.

Cy5.5 未活化的游离酸性花青染料。

General properties

Appearance: copper-violet foam 紫铜泡沫
Molecular weight: 724.63
Molecular formula: C42H35N4BF2O3S
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 589
ε, L⋅mol−1⋅cm−1: 60000
Emission maximum, nm: 616
Fluorescence quantum yield: 0.9
CF260: 0.15
CF280: 0.19
BODIPY™ is registered trademark of Thermo Fisher Scientific in some countries.

BDP TMR DBCO

BDP TMR DBCO,BDP TMR 是一种明亮的高量子产率荧光团，用于 TAMRA 通道，类似于 BODIPY™ TMR。 BDP TMR 对 4 到 10 范围内的 pH 变化不敏感，并且由于其疏水特性可用于对亲脂性化合物进行染色。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • BDP TMR DBCO

BDP TMR DBCO

标签：Cycloalkyne, BDP TMR
货号 规格 价格 货期
124F0 1 mg 110.00$ in stock
224F0 5 mg 210.00$ in stock
424F0 25 mg 410.00$ in stock
524F0 50 mg 695.00$ in stock
624F0 100 mg 1190.00$ in stock

BDP TMR is a bright high quantum yield fluorophore for the TAMRA channel similar to BODIPY™ TMR. BDP TMR is not sensitive to pH changes within the range from 4 to 10 and can be used for staining lipophilic compounds due to its hydrophobic properties.

BDP TMR DBCO enters into bioorthogonal Click Chemistry reactions with molecules that contain an azide fragment. The reaction is promoted by ring strain and undergoes without toxic Cu (I) catalysts.

BDP TMR 是一种明亮的高量子产率荧光团，用于 TAMRA 通道，类似于 BODIPY™ TMR。 BDP TMR 对 4 到 10 范围内的 pH 变化不敏感，并且由于其疏水特性可用于对亲脂性化合物进行染色。

BDP TMR DBCO 与包含叠氮化物片段的分子进行生物正交点击化学反应。 该反应由环应变促进并且在没有有毒的 Cu (I) 催化剂的情况下进行。

Absorption and emission spectra of BDP TMR

BDP TMR DBCO

BDP TMR DBCO相关产品

BDP TMR carboxylic acid

Borondipyrromethene dye for TMR channel with a non-activated carboxylic acid group.

用于 TMR 通道的硼二吡咯亚甲基染料，具有未活化的羧酸基团。

BDP TMR alkyne

Borondipyrromethene dye for TAMRA channel, with alkyne group for copper-catalyzed Click Chemistry.

用于 TAMRA 通道的硼二吡咯亚甲基染料，带有用于铜催化点击化学的炔基。

BDP TMR azide

Borondipyrromethene dye with azido group. Spectral properties are similar to TAMRA dye. Due to long fluorescence lifetime, BDP TMR is especially useful for fluorescence polarization measurements.

具有叠氮基的硼二吡咯亚甲基染料。 光谱特性类似于 TAMRA 染料。 由于荧光寿命长，BDP TMR 特别适用于荧光偏振测量。

General properties

Appearance: red powder with luster 有光泽的红色粉末
Molecular weight: 698.61
Molecular formula: C42H41N4BF2O3
Solubility: good in alcohols, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 542
ε, L⋅mol−1⋅cm−1: 55000
Emission maximum, nm: 574
Fluorescence quantum yield: 0.64
CF260: 0.16
CF280: 0.16
BODIPY™ is a registered trademark of Thermo Fisher Scientific in some countries.

BDP R6G DBCO

BDP R6G DBCO,BDP R6G 是罗丹明 6G (R6G) 的明亮且耐光的替代品。 BDP 代表硼二吡咯亚甲基，一种多功能荧光团支架，在该分子中经过特殊调整以匹配 R6G 的吸收和发射。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • BDP R6G DBCO

BDP R6G DBCO

标签：BDP R6G, Cycloalkyne
货号 规格 价格 货期
A44F0 1 mg 110.00$ in stock
B44F0 5 mg 210.00$ in stock
C44F0 10 mg 310.00$ in stock
D44F0 25 mg 410.00$ in stock
E44F0 50 mg 695.00$ in stock
F44F0 100 mg 1190.00$ in stock

BDP R6G is a bright and photostable substitute for Rhodamine 6G (R6G). BDP stands for borondipyrromethene, a versatile fluorophore scaffold that is specially tuned in this molecule to match absorption and emission of R6G.

DBCO (azodibenzocyclooctyne) is a strained cyclic alkyne that reacts rapidly with azides giving rise to stable triazoles. The reaction does not require to use any catalyst; it is tolerant to most biologically important functional groups.

BDP R6G DBCO is useful for the synthesis of fluorescent conjugates and visualization of azide groups bound to biomolecules and surfaces.

BDP R6G 是罗丹明 6G (R6G) 的明亮且耐光的替代品。 BDP 代表硼二吡咯亚甲基，一种多功能荧光团支架，在该分子中经过特殊调整以匹配 R6G 的吸收和发射。

DBCO（偶氮二苯并环辛炔）是一种应变环状炔烃，可与叠氮化物快速反应生成稳定的三唑。 该反应不需要使用任何催化剂； 它对大多数生物学上重要的官能团具有耐受性。

BDP R6G DBCO 可用于合成荧光偶联物和观察与生物分子和表面结合的叠氮基团。

Absorption and emission spectra of BDP R6G

BDP R6G DBCO

BDP R6G DBCO相关产品

BDP 558/568 alkyne

BDP 558/568 is a borondipyrromethene dye for Cyanine3 channel. This is a terminal alkyne derivative.

BDP 558/568 是一种用于 Cyanine3 通道的硼二吡咯亚甲基染料。 这是一种末端炔烃衍生物。

Azidobutyric acid NHS ester

Activated ester for azido labeling of peptides and proteins.

用于肽和蛋白质的叠氮基标记的活化酯。

BDP R6G azide

BDP R6G is a high performance borondipyrromethene fluorophore which is tuned to match excitation and emission channels of R6G dye.

BDP R6G 是一种高性能硼二吡咯亚甲基荧光团，经过调整以匹配 R6G 染料的激发和发射通道。

General properties

Appearance: red to brown solid 红色至棕色固体
Mass spec M+ increment: 640.3
Molecular weight: 640.53
Molecular formula: C39H35N4BF2O2
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 530
Emission maximum, nm: 548
Fluorescence quantum yield: 0.19
CF260: 0.17
CF280: 0.18

BDP FL DBCO

BDP FL DBCO,BDP FL 是一种用于 FAM（荧光素）通道的光稳定硼二吡咯亚甲基。 该染料与荧光素滤光片组兼容。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • BDP FL DBCO

BDP FL DBCO

标签：BDP FL, Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
A14F0 1 mg 110.00$ in stock
B14F0 5 mg 210.00$ in stock
C14F0 10 mg 310.00$ in stock
D14F0 25 mg 410.00$ in stock
E14F0 50 mg 695.00$ in stock
F14F0 100 mg 1190.00$ in stock

BDP FL DBCO

BDP FL is a photostable borondipyrromethene for FAM (fluorescein) channel. The dye is compatible with filter sets for fluorescein.

This is DBCO (azadibenzocyclooctyne) derivative for copper free Click chemistry reaction with azides.

BDP FL 是一种用于 FAM（荧光素）通道的光稳定硼二吡咯亚甲基。 该染料与荧光素滤光片组兼容。

这是用于与叠氮化物的无铜点击化学反应的 DBCO（氮杂二苯并环辛炔）衍生物。

Absorption and emission spectra of BDP FL

BDP FL DBCO

BDP FL DBCO相关产品

dsGreen Gel Staining Solution, 10000×

dsGreen for staining dsDNA in gels.

dsGreen 用于在凝胶中染色 dsDNA。

Sulfo-Cyanine5-PEG3-Biotin

Conjugate of biotin with sulfo-Cyanine5 emitting in the far-red region of the spectrum.

生物素与在光谱的远红色区域发射的 sulfo-Cyanine5 的结合物。

BDP 650/665 alkyne

BDP 650/665 alkyne is a red emitting BODIPY dye derivative carrying a terminal alkyne group for a copper catalyzed conjugation with azides. Absorption and emission spectra of BDP 650/665 are designed to fit Cy5 channel of various instruments.

BDP 650/665 炔烃是一种发红光的 BODIPY 染料衍生物，带有一个末端炔烃基团，用于铜催化与叠氮化物的共轭。 BDP 650/665 的吸收和发射光谱旨在适应各种仪器的 Cy5 通道。

General properties

Appearance: orange solid 橙色固体
Mass spec M+ increment: 592.3
Molecular weight: 592.49
CAS number: 2360493-46-3
Molecular formula: C35H35N4BF2O2
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 503
ε, L⋅mol−1⋅cm−1: 92000
Emission maximum, nm: 509
Fluorescence quantum yield: 0.97
CF260: 0.015
CF280: 0.027

相关文献：

  1. Merlo, R.; Caprioglio, D.; Cillo, M.; Valenti, A.; Mattossovich, R.; Morrone, C.; Massarotti, A.; Rossi, F.; Miggiano, R.; Leonardi, A.; Minassi, A.; Perugino, G. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36(1), 85–97. doi: 10.1080/14756366.2020.1841182
  2. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156

BDP 650/665 DBCO

BDP 650/665 DBCO,BDP 650/665 是一种明亮的远红荧光染料，其光谱特性类似于 BODIPY™ 650/665 和 Cy™5。 这种高量子产率染料对溶剂极性和 pH 变化相对不敏感。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • BDP 650/665 DBCO

BDP 650/665 DBCO

标签：Cycloalkyne, BDP 650/665
AE4F0 1 mg 110.00$ in stock
BE4F0 5 mg 210.00$ in stock
CE4F0 10 mg 310.00$ in stock
DE4F0 25 mg 410.00$ in stock
EE4F0 50 mg 695.00$ in stock
FE4F0 100 mg 1190.00$ in stock

BDP 650/665 is a bright far-red-fluorescent dye that is similar to BODIPY™ 650/665 and Cy™5 by its spectral characteristics. This high quantum yield dye is relatively non-sensitive to solvent polarity and pH changes.

Due to its significant hydrophobic properties, BDP 650/665 can be used for staining membranes, lipids, and other lipophilic compounds.

DBCO, a substituting group introduced in this molecule, is a dibenzocyclooctyne that is commonly used in copper-free Click Chemistry reactions. BDP 650/665 DBCO can react with various functionalized azides (rapidly and without specialized Cu(I) catalysts) resulting in stable dye-biomolecule conjugates.

BDP 650/665 是一种明亮的远红荧光染料，其光谱特性类似于 BODIPY™ 650/665 和 Cy™5。 这种高量子产率染料对溶剂极性和 pH 变化相对不敏感。

由于其显着的疏水特性，BDP 650/665 可用于染色膜、脂质和其他亲脂性化合物。

DBCO 是该分子中引入的取代基，是一种二苯并环辛炔，常用于无铜点击化学反应。 BDP 650/665 DBCO 可以与各种功能化叠氮化物反应（快速且无需专门的 Cu(I) 催化剂），从而产生稳定的染料-生物分子偶联物。

Absorption and emission spectra of BDP 650/665

BDP 650/665 DBCO

BDP 650/665 DBCO相关产品

Iodo-PEG3-Azide

Iodo-PEG3-Azide is a bifunctional linker with a highly reactive alkylative halogen functional group, and an azido group for Click chemistry / Staudinger ligation.

Iodo-PEG3-Azide 是一种双功能接头，具有高反应性烷基化卤素官能团和用于 Click chemistry / Staudinger ligation 的叠氮基。

DBCO NHS ester

Azodibenzocyclooctyne (DBCO, ADIBO) reagent for strain promoted copper free Click chemistry (spAAC). The reagent contains an NHS ester function for the attachment of the cyclooctyne to various molecules.

用于应变促进无铜点击化学 (spAAC) 的偶氮二苯并环辛炔 (DBCO, ADIBO) 试剂。 该试剂含有 NHS 酯功能，用于将环辛炔连接到各种分子上。

BDP 650/665 alkyne

BDP 650/665 alkyne is a red emitting BODIPY dye derivative carrying a terminal alkyne group for a copper catalyzed conjugation with azides. Absorption and emission spectra of BDP 650/665 are designed to fit Cy5 channel of various instruments.

BDP 650/665 炔烃是一种发红光的 BODIPY 染料衍生物，带有一个末端炔烃基团，用于铜催化与叠氮化物的共轭。 BDP 650/665 的吸收和发射光谱旨在适应各种仪器的 Cy5 通道。

General properties

Appearance: dark blue crystals 深蓝色晶体
Molecular weight: 733.61
Molecular formula: C44H38N5BF2O3
Solubility: good in DMF, DMSO, dichloromethane
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 649
ε, L⋅mol−1⋅cm−1: 94000
Emission maximum, nm: 667
Fluorescence quantum yield: 0.52
CF260: 0.04
CF280: 0.04
BODIPY™ is a registered trademark of Thermo Fisher Scientific in some countries. Cy™ is a registered trademark of Cytiva in some countries.

BDP 581/591 DBCO

BDP 581/591 DBCO,BDP 581/591 是一种具有共轭烯烃体系的硼二吡咯亚甲基染料。 它既可以用作常规荧光团，也可以用作检测活性氧 (ROS) 的探针； 氧化后，其荧光移至光谱的绿色部分。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • BDP 581/591 DBCO

BDP 581/591 DBCO

标签：BDP 581/591, Cycloalkyne
货号 规格 价格 货期
A64F0 1 mg 110.00$ in stock
B64F0 5 mg 210.00$ in stock
C64F0 10 mg 310.00$ in stock
D64F0 25 mg 410.00$ in stock
E64F0 50 mg 695.00$ in stock
F64F0 100 mg 1190.00$ in stock

BDP 581/591 is a borondipyrromethene dye with a conjugated olefinic system. It can be used either as a regular fluorophore, or as a probe for the detection of reactive oxygen species (ROS); after oxidation, its fluorescence moves to the green part of the spectrum.

This is a version of the dye containing cyclooctyne. The DBCO (azodibenzocyclooctyne) moiety can be conjugated with azides yielding stable triazole conjugates.

BDP 581/591 是一种具有共轭烯烃体系的硼二吡咯亚甲基染料。 它既可以用作常规荧光团，也可以用作检测活性氧 (ROS) 的探针； 氧化后，其荧光移至光谱的绿色部分。

这是一种含有环辛炔的染料。 DBCO（偶氮二苯并环辛炔）部分可以与叠氮化物缀合，产生稳定的三唑缀合物。

Absorption and emission spectra of BDP 581/591

BDP 581/591 DBCO

BDP 581/591 DBCO相关产品

BDP 581/591 tetrazine

BDP 581/591 is a borondipyrromethene dye with tetrazine group for the inverse electron demand Diels-Alder (IEDDA) ligation.

BDP 581/591 是一种带有四嗪基团的硼二吡咯亚甲基染料，用于逆电子需求 Diels-Alder (IEDDA) 连接。

Sulfo-Cyanine5 NHS ester

Water-soluble Cyanine 5 succinimide ester.

水溶性Cy5琥珀酰亚胺酯。

BDP 630/650 alkyne

Alkyne dye for copper catalyzed Click chemistry, containing borondipyrromethene fluorophore BDP 630/650 for red channel.

用于铜催化点击化学的炔烃染料，含有用于红色通道的硼二吡咯亚甲基荧光团 BDP 630/650。

General properties

Appearance: dark purple solid 深紫色固体
Mass spec M+ increment: 692.3
Molecular weight: 692.60
Molecular formula: C43H39N4BF2O2
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 585
ε, L⋅mol−1⋅cm−1: 104000
Emission maximum, nm: 594
Fluorescence quantum yield: 0.83
CF260: 0.06
CF280: 0.04

BDP 558/568 DBCO

BDP 558/568 DBCO,BDP 558/568 荧光最大值在黄色光谱范围 (569 nm) 内。 这种染料的光谱特性类似于 BODIPY™ 558/568、Cy3™、DyLight™ 549 等荧光团。 它可溶于极性有机溶剂，具有良好的光稳定性和高量子产率。

  • Products
  • Reactive dyes
  • Cycloalkyne dyes
  • BDP 558/568 DBCO

BDP 558/568 DBCO

标签：Cycloalkyne, BDP 558/568
货号 规格 价格 货期
174F0 1 mg 110.00$ in stock
274F0 5 mg 210.00$ in stock
374F0 10 mg 310.00$ in stock
474F0 25 mg 410.00$ in stock
574F0 50 mg 695.00$ in stock
674F0 100 mg 1190.00$ in stock

BDP 558/568 fluorescence maximum is in the yellow spectrum range (569 nm). This dye is an analog of such fluorophores as BODIPY™ 558/568, Cy3™, DyLight™ 549 by its spectral characteristics. It is soluble in polar organic solvents and has good photostability and high quantum yield.

BDP 558/568 has hydrophobic properties and can be used for staining lipids, membranes, and other lipophilic compounds.

Introduced in the BDP 558/568 molecule, the cyclooctyne functional group allows entering into reactions of 1,3-dipolar cycloaddition with various substituted azides. Such reactions are promoted by ring strain and do not require copper catalysis. Thus, this method can be used for investigating various processes in living cells.

BDP 558/568 DBCO can be used for the detection of target molecules, proteins, or nucleic acids that contain azide groups by microscopy and flow cytometry.

BDP 558/568 荧光最大值在黄色光谱范围 (569 nm) 内。 这种染料的光谱特性类似于 BODIPY™ 558/568、Cy3™、DyLight™ 549 等荧光团。 它可溶于极性有机溶剂，具有良好的光稳定性和高量子产率。

BDP 558/568 具有疏水性，可用于染色脂质、膜和其他亲脂性化合物。

在 BDP 558/568 分子中引入的环辛炔官能团允许与各种取代的叠氮化物进行 1,3-偶极环加成反应。 这种反应由环应变促进，不需要铜催化。 因此，该方法可用于研究活细胞中的各种过程。

BDP 558/568 DBCO 可用于通过显微镜和流式细胞术检测含有叠氮基的靶分子、蛋白质或核酸。

Absorption and emission spectra of BDP 558/568

BDP 558/568 DBCO

BDP 558/568 DBCO相关产品

BDP 558/568 azide

BDP 558/568 is a borondipyrromethene fluorophore with absorption and emission spectra close to Cyanine3. This is an azide derivative for Click chemistry.

BDP 558/568 是一种硼二吡咯亚甲基荧光团，其吸收和发射光谱接近于 Cy3。 这是一种用于点击化学的叠氮化物衍生物。

BDP 558/568 alkyne

BDP 558/568 is a borondipyrromethene dye for Cyanine3 channel. This is a terminal alkyne derivative.

BDP 558/568 是一种用于 Cy3 通道的硼二吡咯亚甲基染料。 这是一种末端炔烃衍生物。

Cyanine3 DBCO

Cyanine3 dibenzocyclooctyne (DBCO, or ADIBO) is a cycloalkyne dye derivative for copper free Click chemistry.

Cy3 dibenzocyclooctyne (DBCO, or ADIBO) 是一种用于无铜点击化学的环炔烃染料衍生物。

General properties

Appearance: brown powder with luster 有光泽的棕色粉末
Molecular weight: 646.56
Molecular formula: C37H33N4BF2O2S
Solubility: very soluble in DMF, DMSO, dichloromethane
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 561
ε, L⋅mol−1⋅cm−1: 84400
Emission maximum, nm: 569
Fluorescence quantum yield: 0.68
CF260: 0.00
CF280: 0.07
BODIPY™, DyLight™ are registered trademarks of Thermo Fisher Scientific in some countries. Cy™ is a registered trademark of Cytiva in some countries.