标签： Cyanine7

Cyanine7 DBCO

Cyanine7 DBCO,Cy7 DBCO 是一种具有环炔部分的 NIR 荧光染料，用于通过无铜、应变促进的炔烃叠氮化物环加成 (spAAC) 与叠氮化物结合。

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  • Cyanine7 DBCO

Cyanine7 DBCO

标签：Cyanine7, Copper free Click chemistry, Cycloalkyne
货号 规格 价格 货期
A50F0 1 mg 110.00$ in stock
B50F0 5 mg 210.00$ in stock
C50F0 10 mg 310.00$ in stock
D50F0 25 mg 410.00$ in stock
E50F0 50 mg 695.00$ in stock
F50F0 100 mg 1190.00$ in stock

Cyanine7 DBCO is a NIR fluorescent dye with cycloalkyne moiety for the conjugation with azides by means of copper-free, strain promoted alkyne azide cycloaddition (spAAC).

Azodibenzocyclooctyne (DBCO or ADIBO) fragment is a stable but active cycloalkyne that reacts very rapidly with azides.

Cy7 DBCO 是一种具有环炔部分的 NIR 荧光染料，用于通过无铜、应变促进的炔烃叠氮化物环加成 (spAAC) 与叠氮化物结合。

偶氮二苯并环辛炔（DBCO 或 ADIBO）片段是一种稳定但具有活性的环炔烃，可与叠氮化物快速反应。

Absorption and emission spectra of Cyanine7 fluorophore

Cyanine7 DBCO

Cyanine7 DBCO相关产品

BDP 630/650 maleimide

BDP 630/650 maleimide is a thiol reactive, borondipyrromethene based dye tuned to match the far red channel of Cyanine5 fluorophore.

BDP 630/650 马来酰亚胺是一种硫醇反应性、基于硼二吡咯亚甲基的染料，经过调整以匹配 Cy5 荧光团的远红通道。

Sulfo-Cyanine5.5 carboxylic acid

Water soluble far red fluorescent dye sulfo-Cyanine5.5, free non-activated carboxylic acid. Useful for the calibration, and as a non-reactive control.

水溶性远红荧光染料sulfo-Cy5.5，游离非活化羧酸。 用于校准，并作为非反应控制。

EdU (5-ethynyl-2′-deoxyuridine)

EdU is a nucleoside which is incorporated into replicated DNA by cellular enzymes. After it, DNA contained in the cells can be developed by Click chemistry reaction with fluorescent dye azides to reveal cell proliferation.

EdU 是一种核苷，可通过细胞酶掺入复制的 DNA 中。 之后，细胞中所含的 DNA 可以通过与荧光染料叠氮化物的 Click 化学反应进行显色，以揭示细胞增殖情况。

General properties

Appearance: dark green solid 深绿色固体
Mass spec M+ increment: 849.5
Molecular weight: 885.62
CAS number: 2692677-77-1
Molecular formula: C58H65N4ClO2
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 12 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 12 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Islam, M.R.; Nguy, C.; Pandit, S.; Lyon, L.A. Design and Synthesis of Core–Shell Microgels with One‐Step Clickable Crosslinked Cores and Ultralow Crosslinked Shells. Macromolecular Chemistry and Physics, 2020, 221(19), 2000156. doi: 10.1002/macp.202000156
  2. Alberg, I.; Kramer, S.; Schinnerer, M.; Hu, Q.; Seidl, C.; Leps, C.; Drude, N.; Möckel, D.; Rijcken, C.; Lammers, T.; Diken, M.; Maskos, M.; Morsbach, S.; Landfester, K.; Tenzer, S.; Barz, M.; Zentel, R. Polymeric Nanoparticles with Neglectable Protein Corona. Small, 2020, 16(18), 1907574. doi: 10.1002/smll.201907574

Cyanine7 tetrazine

Cyanine7 tetrazine,TCO 连接是在四嗪和应变烯烃（例如反式-环辛烯）之间发生的反应。这种四嗪带有一个近红外染料的片段，Cyanine7。 这种 NIR 荧光团对于体内成像特别有用。

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Cyanine7 tetrazine

标签：Cyanine7,Cy7, Tetrazine, Copper free Click chemistry
货号 规格 价格 货期
150E0 1 mg 110.00$ in stock
250E0 5 mg 290.00$ in stock
450E0 25 mg 690.00$ in stock
550E0 50 mg 1270.00$ in stock
650E0 100 mg 1990.00$ in stock

TCO ligation is a reaction that takes place between a tetrazine and a strained olefin, such as trans-cyclooctene.

This tetrazine bears a fragment of near infrared dye, Cyanine7. This NIR fluorophore is especially useful for in vivo imaging.

TCO 连接是在四嗪和应变烯烃（例如反式-环辛烯）之间发生的反应。

这种四嗪带有一个近红外染料的片段，Cyanine7。 这种 NIR 荧光团对于体内成像特别有用。

Absorption and emission spectra of Cyanine7

Cyanine7 tetrazine

Cyanine7 tetrazine相关产品

Cyanine5.5 tetrazine

A compound containing Cyanine5.5 fluorophore, a far red emitting dye, and tetrazine fragment for the conjugation with trans-cyclooctenes / cyclopropenes via TCO ligation.

一种含有 Cy5.5 荧光团、一种远红光发射染料和四嗪片段的化合物，用于通过 TCO 连接与反式环辛烯/环丙烯共轭。

Cyanine7.5 tetrazine

Cyanine7.5 is a NIR fluorescent dye with absorption and emission spectra similar to ICG (indocyanine green), but possessing a higher fluorescence quantum yield. This derivative is a tetrazine derivative for the TCO ligation reaction.

Cy7.5 是一种近红外荧光染料，其吸收和发射光谱类似于 ICG（吲哚菁绿），但具有更高的荧光量子产率。 该衍生物是用于 TCO 连接反应的四嗪衍生物。

Cyanine7 DBCO

NIR fluorescent dye functionalized with cyclooctyne moiety for copper free Click chemistry conjugation with azides.

用环辛炔部分功能化的 NIR 荧光染料，用于与叠氮化物的无铜点击化学缀合。

General properties

Appearance: dark colored solid  深色固体
Mass spec M+ increment: 703.4
Molecular weight: 877.94
Molecular formula: C47H54N7F6OP
Solubility: good in DMF, DMSO, DCM
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
CF260: 0.022
CF280: 0.029

Cyanine7 amine

Cyanine7 amine,具有游离胺基的近红外染料，用于与活化酯和其他反应性分子结合。Cyanine7 是一种近红外染料，是 Cy7® 的类似物，特别适用于活体生物成像和要求低背景的应用。

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Cyanine7 amine

标签：Cyanine7, Cy7, Amines, Near infrared (NIR) imaging
货号 规格 价格 货期
150C0 1 mg 110.00$ in stock
250C0 5 mg 210.00$ in stock
450C0 25 mg 410.00$ in stock
550C0 50 mg 695.00$ in stock
650C0 100 mg 1190.00$ in stock

Near infrared dye with free amine group for the conjugation with activated esters and other reactive molecules.

Cyanine7 is a near infrared dye, an analog of Cy7® which is especially suitable for live organism imaging, and demanding low-background applications.

具有游离胺基的近红外染料，用于与活化酯和其他反应性分子结合。

Cyanine7 是一种近红外染料，是 Cy7® 的类似物，特别适用于活体生物成像和要求低背景的应用。

Cy7 absorbance and emission spectra

Cyanine7 amine

Cyanine7 amine相关产品

Cyanine5 hydrazide

Cy5 hydrazide is a reactive dye for aldehydes and ketones. It can be used for the labeling of glycoproteins after periodate oxidation of sugar moieties.

Cy5 酰肼是醛和酮的活性染料。 它可用于糖部分高碘酸氧化后的糖蛋白的标记。

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AF488 azide

AF488 azide is a fluorophore with emission in the green spectrum range. It reacts with alkynes in copper-catalyzed cycloaddition reactions.

AF488 azide 是一种在绿色光谱范围内发射的荧光团。 它在铜催化的环加成反应中与炔烃反应。

Cyanine7 carboxylic acid

Non-reactive, near-infrared fluorescent dye.

非反应性近红外荧光染料。

General properties

Appearance: green powder 绿色粉末
Molecular weight: 719.87
CAS number: 1650635-41-8, 1650559-73-1 [Cl-]
Molecular formula: C43H60Cl2N4O
Solubility: soluble in water (72 mM = 51 g/L), well soluble in DMSO, DMF, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Ford, C.A.; Spoonmore, T.J.; Gupta, M.K.; Duvall, C.L.; Guelcher, S.A.; Cassat, J.E. Diflunisal-loaded poly(propylene sulfide) nanoparticles decrease S. aureus-mediated bone destruction during osteomyelitis. Journal of Orthopaedic Research, 2021, 39(2), 426–437. doi: 10.1002/jor.24948
  2. Shao, Z.; Flynn, R.A.; Crowe, J.L.; Zhu, Y.; Liang, J.; Jiang, W.; Aryan, F.; Aoude, P.; Bertozzi, C.R.; Estes, V.M.; Lee, B.J.; Bhagat, G.; Zha, S.; Calo, E. DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis. Nature, 2020, 579, 291–296. doi: 10.1038/s41586-020-2041-2
  3. de Oliveira, J.K.; Ueda-Nakamura, T.; Corrêa, A.G.; Petrilli, R.; Lopez, R.F.V.; Nakamura, C.V.; Auzely-Velty, R. Liposome-based nanocarrier loaded with a new quinoxaline derivative for the treatment of cutaneous leishmaniasis. Materials Science and Engineering: C, 2020, 110, 110720. doi: 10.1016/j.msec.2020.110720
  4. Pola, R.; Böhmová, E.; Filipová, M.; Pechar, M.; Pankrác, J.; Větvička, D.; Olejár, T.; Kabešová, M.; Poučková, P.; Šefc, L.; Zábrodský, M.; Janoušková, O.; Bouček, J.; Etrych, T. Targeted Polymer-Based Probes for Fluorescence Guided Visualization and Potential Surgery of EGFR-Positive Head-and-Neck Tumors. Pharmaceutics, 2020, 12, 31. doi: 10.3390/pharmaceutics12010031
Cy® is a trademark of GE Healthcare.

Cyanine7 dicarboxylic acid

Cyanine7 dicarboxylic acid,Cy7 二羧酸是一种带有两个羧基的双功能染料分子。 Cy7 具有近红外荧光。

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Cyanine7 dicarboxylic acid

标签：Cyanine7, Cy7, Carboxylic acids
货号 规格 价格 货期
1512-1mg 1 mg 110.00$ in stock
1512-5mg 5 mg 210.00$ in stock
1512-25mg 25 mg 410.00$ in stock
1512-50mg 50 mg 695.00$ in stock
1512-100mg 100 mg 1190.00$ in stock

Cyanine7 dicarboxylic acid is a bifunctional dye molecule bearing two carboxylic groups. Cyanine7 possesses near infrared fluorescence.

Cyanine7 二羧酸是一种带有两个羧基的双功能染料分子。 Cyanine7 具有近红外荧光。

Absorption and emission spectra of Cyanine7 fluorophore

Cyanine7 dicarboxylic acid

Cyanine7 dicarboxylic acid相关产品

sulfo-Cyanine7 dicarboxylic acid

Sulfo-Cyanine7 dicarboxylic acid is a bifunctional dye with two carboxyl groups.

Sulfo-Cy7 二羧酸是一种具有两个羧基的双功能染料。

Sulfo-Cyanine5 bis-NHS ester

Water soluble amine reactive Cyanine5 dye with two NHS ester groups.

具有两个 NHS 酯基团的水溶性胺活性 Cyanine5 染料。

General properties

Appearance: dark green solid 深绿色固体
Molecular weight: 685.33
Molecular formula: C42H53N2ClO4
Solubility: good in DCM, DMF, DMSO
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

Cyanine7 carboxylic acid

Cyanine7 carboxylic acid,游离未活化的Cy7染料羧酸。 近红外荧光染料。对于偶联和标记反应，还可以考虑使用预活化的 Cy7 NHS 酯或水溶性磺基-Cyanine7 NHS 酯。

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  • Cyanine7 carboxylic acid

Cyanine7 carboxylic acid

标签：Cyanine7,Cy7, Carboxylic acids, Near infrared (NIR) imaging
货号 规格 价格 货期
15090 1 mg 110.00$ in stock
25090 5 mg 210.00$ in stock
45090 25 mg 410.00$ in stock
55090 50 mg 695.00$ in stock
65090 100 mg 1190.00$ in stock

Free unactivated Cyanine7 dye carboxylic acid. Near-infrared fluorescent dye.

For coupling and labeling reactions also consider using pre-activated Cyanine7 NHS ester, or water-soluble sulfo-Cyanine7 NHS ester.

游离未活化的Cy7染料羧酸。 近红外荧光染料。

对于偶联和标记反应，还可以考虑使用预活化的 Cy7 NHS 酯或水溶性磺基-Cyanine7 NHS 酯。

Cyanine7 absorbance and emission spectra

Cyanine7 carboxylic acid

Cyanine7 carboxylic acid相关产品

Alkyne Phosphoramidite, 5′-terminal

Alkyne phosphoramidite for the synthesis of oligonucleotides ready for Click chemistry.

用于合成寡核苷酸的炔亚磷酰胺，可用于点击化学。

FAM amine, 5-isomer

Amino derivative of fluorescein, pure 5-isomer. Contains a linker arm between the aliphatic amine group, and the fluorophore. Useful for the labeling via enzymatic transamination, for the reactions with electrophilic reagents, and for reductive amination.

荧光素的氨基衍生物，纯 5-异构体。 在脂肪胺基团和荧光团之间包含一个连接臂。 可用于通过酶促氨基转移进行标记、与亲电子试剂的反应以及还原胺化。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

General properties

Appearance: green powder 绿色粉末
Molecular weight: 585.22
CAS number: 1628790-40-8 (chloride), 1628897-82-4 (without anion), 2241083-63-4 (inner salt)
Molecular formula: C37H45ClN2O2
IUPAC name: 3H-​Indolium, 2-​[2-​[3-​[2-​[1-​(5-​carboxypentyl)​-​1,​3-​dihydro-​3,​3-​dimethyl-​2H-​indol-​2-​ylidene]​ethylidene]​-​1-​cyclohexen-​1-​yl]​ethenyl]​-​1,​3,​3-​trimethyl-​, chloride
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
CF260: 0.022
CF280: 0.029

相关文献：

  1. Matoori, S.; Mooney, D.J. Near-Infrared Fluorescence Hydrogen Peroxide Assay for Versatile Metabolite Biosensing in Whole Blood. Small, 2020, 16(20), 2000369. doi: 10.1002/smll.202000369
  2. Svenskaya, Y.I.; Genina, E.A.; Parakhonskiy, B.V.; Lengert, E.; Talnikova, E.E.; Terentyuk, G.S.; Utz, S.R.; Gorin, D.A.; Tuchin, V.V.; Sukhorukov, G. A simple non-invasive approach towards efficient transdermal drug delivery based on biodegradable particulate system. ACS Applied Materials & Interfaces, 2019, 11(19), 17270–17282. doi: 10.1021/acsami.9b04305
  3. Yang, C.; Liu, D.; Renny, A.; Kuttipillai, P.S.; Lunt, R.R. Integration of near-infrared harvesting transparent luminescent solar concentrators onto arbitrary surfaces. Journal of Luminescence, 2019, 210, 239–246. doi: 10.1016/j.jlumin.2019.02.042
  4. Luthman, A.S. Wide-Field fHSI with a Linescan SRDA. In: Spectrally Resolved Detector Arrays for Multiplexed Biomedical Fluorescence Imaging (Springer Thesis), 2018, 51–85. doi: 10.1007/978-3-319-98255-7_3
Cy® is a trademark of GE Healthcare.

Cyanine7 hydrazide

Cyanine7 hydrazide,Cy7 的酰肼衍生物，一种 NIR 荧光染料，是 Cy7® 的类似物。这种七次甲基荧光团包含一个六元环，使聚次甲基链刚性化，与母体结构相比，量子产率提高了 20%。

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  • Cyanine7 hydrazide

Cyanine7 hydrazide

标签：Cyanine7,Cy7, Hydrazides, Near infrared (NIR) imaging
货号 规格 价格 货期
15070 1 mg 110.00$ in stock
25070 5 mg 210.00$ in stock
45070 25 mg 410.00$ in stock
55070 50 mg 695.00$ in stock
65070 100 mg 1190.00$ in stock

Hydrazide derivative of Cyanine7, a NIR fluorescent dye, an analog of Cy7®.

This variety of heptamethine fluorophore contains a six-membered ring rigidizing the polymethine chain which allows to increase quantum yield by 20% compared to parent structure.

Hydrazide reacts quickly and smoothly with aldehydes and ketones yielding stable hydrazone products. This reaction is also good for the labeling of glycoproteins after periodate oxidation.

Cy7 的酰肼衍生物，一种 NIR 荧光染料，是 Cy7® 的类似物。

这种七次甲基荧光团包含一个六元环，使聚次甲基链刚性化，与母体结构相比，量子产率提高了 20%。

酰肼与醛类和酮类反应迅速而平稳，产生稳定的腙产物。 该反应也有利于高碘酸氧化后糖蛋白的标记。

Cyanine7 absorbance and emission spectra

Cyanine7 hydrazide

Cyanine7 hydrazide相关产品

Cyanine3 carboxylic acid

Free Cyanine3 carboxylic acid.

游离Cy3羧酸。

Cyanine5.5 NHS ester

Cyanine5.5 NHS is far-red / near-infrared amine-reactive dye.

Cy5.5 NHS 是远红/近红外胺活性染料。

Cyanine5.5 maleimide

Cyanine5.5 maleimide is a thiol reactive dye for protein labeling.

Cy5.5 马来酰亚胺是一种用于蛋白质标记的硫醇活性染料。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 544.8
Molecular weight: 635.70
CAS number: 2183440-61-9 (without anion)
Molecular formula: C37H48Cl2N4O
Solubility: moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Lix, K.; Krause, K.D.; Kim, H.; Algar, W.R. Investigation of the Energy Transfer Mechanism Between Semiconducting Polymer Dots and Organic Dyes. Journal of Physical Chemistry C, 2020, 124(31), 17387–17400. doi: 10.1021/acs.jpcc.0c04983
Cy® is a trademark of GE Healthcare.

Cyanine7 maleimide

Cyanine7 maleimide,近红外、巯基反应性 Cy7 染料，Cy7® 马来酰亚胺的类似物。该试剂允许将近红外 Cyanine7 染料连接到具有游离巯基的蛋白质上。 由此获得的标记蛋白质用于近红外生物成像应用。 NIR 成像系统可用于可视化标记蛋白质在组织中的分布，甚至在活生物体中。

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  • Cyanine7 maleimide

Cyanine7 maleimide

标签：Cyanine7,Cy7, Maleimides, Near infrared (NIR) imaging
货号 规格 价格 货期
15080 1 mg 110.00$ in stock
25080 5 mg 210.00$ in stock
45080 25 mg 410.00$ in stock
55080 50 mg 695.00$ in stock
65080 100 mg 1190.00$ in stock

Near-infrared, sulfhydryl reactive Cyanine7 dye, an analog of Cy7® maleimide.

This reagent allows to attach near infrared Cyanine7 dye to proteins with free sulfhydryl groups. Labeled proteins thus obtained are used in NIR bioimaging applications. NIR imaging systems can be used to visualize distribution of labeled proteins in tissues even in live organism.

近红外、巯基反应性 Cy7 染料，Cy7® 马来酰亚胺的类似物。

该试剂允许将近红外 Cyanine7 染料连接到具有游离巯基的蛋白质上。 由此获得的标记蛋白质用于近红外生物成像应用。 NIR 成像系统可用于可视化标记蛋白质在组织中的分布，甚至在活生物体中。

Cyanine7 absorbance and emission spectra

Cyanine7 maleimide

Cyanine7 maleimide相关产品

Cyanine7 NHS ester

Amine reactive NHS ester of near infrared dye Cyanine7.

近红外染料Cy7的胺活性NHS酯。

Cyanine7 tetrazine

Near infrared Cyanine7 dye derivative containing tetrazine group for TCO ligation.

用于 TCO 连接的含有四嗪基团的近红外 Cy7 染料衍生物。

AF488 NHS ester

AF488 NHS ester, a bright, photostable and hydrophilic fluorescent dye for green channel.

AF488 NHS 酯，一种用于绿色通道的明亮、光稳定性和亲水性荧光染料。

General properties

Appearance: green powder 绿色粉末
Molecular weight: 707.34
CAS number: 2120392-49-4 (without anion)
Molecular formula: C43H51ClN4O3
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Liu, Y.; Fens, M.H.A.M.; Lou, B.; van Kronenburg, N.C.H.; Maas-Bakker, R.F.M.; Kok, R.J.; Oliveira, S.; Hennink, W.E.; van Nostrum, C.F. π-π-Stacked Poly(ε-caprolactone)-b-poly(ethylene glycol) Micelles Loaded with a Photosensitizer for Photodynamic Therapy. Pharmaceutics, 2020, 12(4), 338. doi: 10.3390/pharmaceutics12040338
  2. Liu, Y.; Scrivano, L.; Peterson, J.D.; Fens, M.H.A.M.; Beltrán Hernández, I.; Mesquita, B.; Sastre Torano, J.; Hennink, W.E.; van Nostrum, C.F.; Oliveira, S. EGFR targeted nanobody functionalized polymeric micelles loaded with mTHPC for selective photodynamic therapy. Molecular Pharmaceutics, 2020, 17(4), 1276–1292. doi: 10.1021/acs.molpharmaceut.9b01280
  3. Melgar-Asensio, I.; Kandela, I.; Aird, F.; Darjatmoko, S.R.; de Los Rios, C.; Sorenson, C.M.; Albert, D.M.; Sheibani, N.; Henkin, J. Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Investigative Ophthalmology & Visual Science, 2018, 59(10), 4071–4081. doi: 10.1167/iovs.18-24087
  4. Matsuoka, D.; Watanabe, H.; Shimizu, Y.; Kimura, H.; Yagi, Y.; Kawai, R.; Ono, M.; Saji, H. Structure–activity relationships of succinimidyl-Cys-C (O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorganic & Medicinal Chemistry, 2018, 26(9), 2291–2301. doi: 10.1016/j.bmc.2018.03.015
Cy® is a trademark of GE Healthcare.

Cyanine7 alkyne

Cyanine7 alkyne,Cyanine7 的炔烃衍生物，一种近红外荧光团，Cy7® 的类似物。 炔烃可以通过铜催化的点击化学与多种叠氮化物结合。该染料在水中的溶解度有限，但可以在添加 DMSO 或 DMF 的水性缓冲液中成功偶联。

  • Products
  • Reactive dyes
  • Dye alkynes
  • Cyanine7 alkyne

Cyanine7 alkyne

标签：Cyanine7, Cy7,Alkynes, Near infrared (NIR) imaging
货号 规格 价格 货期
A50B0 1 mg 110.00$ in stock
B50B0 5 mg 210.00$ in stock
C50B0 10 mg 310.00$ in stock
D50B0 25 mg 410.00$ in stock
E50B0 50 mg 695.00$ in stock
F50B0 100 mg 1190.00$ in stock

Alkyne derivative of Cyanine7, a near infrared fluorophore, analog of Cy7®. The alkyne can be conjugated to a variety of azides via copper-catalyzed Click chemistry.

The dye has limited solubility in water, but it can be successfully conjugated in aqueous buffers with the addition of DMSO or DMF.

Cyanine7 的炔烃衍生物，一种近红外荧光团，Cy7® 的类似物。 炔烃可以通过铜催化的点击化学与多种叠氮化物结合。

该染料在水中的溶解度有限，但可以在添加 DMSO 或 DMF 的水性缓冲液中成功偶联。

Cyanine7 absorbance and emission spectra

Cyanine7 alkyne

Cyanine7 alkyne相关产品

Cyanine5 azide

Cyanine5 azide is a reagent for Click Chemistry labeling with Cyanine5, a popular fluorescent dye.

Cy5 azide 是一种用 Cy5（一种流行的荧光染料）进行 Click Chemistry 标记的试剂。

Cyanine7 maleimide

Cyanine7 maleimide is a sulfhydryl-reactive NIR dye.

Cy7 马来酰亚胺是一种巯基反应性 NIR 染料。

Cyanine3.5 NHS ester

Cyanine3.5 dye NHS ester derivative.

Cy3.5染料NHS酯衍生物。

General properties

Appearance: green powder 绿色粉末
Mass spec M+ increment: 586.4
Molecular weight: 622.28
CAS number: 1998119-13-3 (chloride), 1954687-62-7
Molecular formula: C40H48ClN3O
Solubility: good in DMSO, DMF, alcohols
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Kocere, A.; Resseguier, J.; Wohlmann, J.; Skjeldal, F.M.; Khan, S.; Speth, M.; Dal, N.-J.K.; Ng, M.Y.W.; Alonso-Rodriguez, N.; Scarpa, E.; Rizzello, L.; Battaglia, G.; Griffiths, G.; Fenaroli, F. Real-time imaging of polymersome nanoparticles in zebrafish embryos engrafted with melanoma cancer cells: Localization, toxicity and treatment analysis. EBioMedicine, 2020, 58, 102902. doi: 10.1016/j.ebiom.2020.102902
  2. Hwang, D.; Nilchan, N.; Nanna, A.R.; Li, X.; Cameron, M.D.; Roush, W.R.; Park, H.; Rader, C. Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues. Cell Chemical Biology, 2019, 26(9), 1229–1239. doi: 10.1016/j.chembiol.2019.05.010
  3. Conibear, A.C.; Thewes, K.; Groysbeck, N.; Becker, C.F.W. Multifunctional Scaffolds for Assembling Cancer-Targeting Immune Stimulators Using Chemoselective Ligations. Frontiers in Chemistry, 2019, 7, 113. doi: 10.3389/fchem.2019.00113
  4. Tang, H.; Zhang, J.; Tang, J.; Shen, Y.; Guo, W.; Zhou, M.; Wang, R.; Jiang, N.; Gan, Z.; Yu, Q. Tumor specific and renal excretable star-like tri-block polymer-doxorubicin conjugates for safe and efficient anticancer therapy. Biomacromolecules, 2018, 19(7), 2849–2862. doi: 10.1021/acs.biomac.8b00425
Cy® is a trademark of GE Healthcare.

Cy7 azide,Cy7 叠氮化物

Cy7 azide,Cy7 叠氮化物,Cyanine7 azide 是一种用于 Click Chemistry 标记的近红外荧光染料叠氮化物，是 Cy7® 叠氮化物的类似物。该产品可用于通过 Click Chemistry 将 Cy7 结合到各种炔基化生物分子中。 使用这种叠氮化物也可以对寡核苷酸进行合成后修饰。环己烷桥接的聚甲炔链允许量子产率增加 20%（与母体非桥接结构相比）。

  • Products
  • Reactive dyes
  • Dye azides
  • Cyanine7 azide

Cyanine7 azide

标签：Cyanine7,Cy7, Azides, Near infrared (NIR) imaging
货号 规格 价格 货期
15030 100 uL, 10 mM/DMSO 110.00$ in stock
35030 500 uL, 10 mM/DMSO 210.00$ in stock
45030 1 mL, 10 mM/DMSO 410.00$ in stock
A5030 1 mg 110.00$ in stock
B5030 5 mg 210.00$ in stock
C5030 10 mg 310.00$ in stock
D5030 25 mg 410.00$ in stock
E5030 50 mg 695.00$ in stock

Cyanine7 azide is a near-infrared fluorescent dye azide for Click Chemistry labeling, an analog of Cy7® azide.

This product can be used for the incorporation of Cyanine7 into various alkynylated biomolecules via Click Chemistry. Post-synthetic modification of oligonucleotides is also possible with this azide.

Cyclohexane-bridged polymethyne chain allows for 20% increase in quantum yield (compared to parent non-bridged structure).

Cyanine7 azide 是一种用于 Click Chemistry 标记的近红外荧光染料叠氮化物，是 Cy7® 叠氮化物的类似物。

该产品可用于通过 Click Chemistry 将 Cy7 结合到各种炔基化生物分子中。 使用这种叠氮化物也可以对寡核苷酸进行合成后修饰。

环己烷桥接的聚甲炔链允许量子产率增加 20%（与母体非桥接结构相比）。

Cyanine7 absorbance and emission spectra

Cyanine7 azide

Cy7 azide,Cy7 叠氮化物相关产品

Cyanine5 alkyne

Cyanine5 alkyne is an alkyne dye for Click Chemistry.

Cy5 炔烃是一种用于 Click Chemistry 的炔烃染料。

Sulfo-Cyanine7 amine

Water-soluble NIR dye amine, sulfonated derivative of Cyanine7 dye, for the modification via enzymatical transamination.

水溶性 NIR 染料胺，Cy7 染料的磺化衍生物，用于通过酶促氨基转移进行修饰。

Copper(II)-TBTA complex, 10 mM in 55% aq. DMSO

Catalyst for bioconjugate synthesis by Click Chemistry.

Click Chemistry 用于生物共轭合成的催化剂。

General properties

Appearance: green powder / solution
Molecular weight: 667.33
CAS number: 1557149-65-1 (chloride), 1557397-59-7
Molecular formula: C40H51ClN6O
Solubility: soluble in organic solvents (DMSO, DMF, dichloromethane), low solubility in water
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

储存：收到后 24 个月，在 -20°C 避光保存。 运输：在室温下长达 3 周。 避免长时间暴露在光线下。 干燥。
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 750
ε, L⋅mol−1⋅cm−1: 199000
Emission maximum, nm: 773
Fluorescence quantum yield: 0.3
CF260: 0.022
CF280: 0.029

相关文献：

  1. Roberts, S.; Khera, E.; Choi, C.; Navaratna, T.; Grimm, J.; Thurber, G.M.; Reiner, T. Optoacoustic imaging of Glucagon-like Peptide 1 Receptor with a near-infrared exendin-4 analog. Journal of Nuclear Medicine, 2021, 62(6), 839–848. doi: 10.2967/jnumed.120.252262
  2. Thauvin, C.; Maudens, P.; Allémann, E. Microwave-assisted synthesis of self-assembling bi-functionalizable amphiphilic diblock copolymers. Journal of Drug Delivery Science and Technology, 2021, 61, 102255. doi: 10.1016/j.jddst.2020.102255
  3. Meka, R.R.; Venkatesha, S.H.; Moudgil, K.D. Peptide-directed liposomal delivery improves the therapeutic index of an immunomodulatory cytokine in controlling autoimmune arthritis. Journal of Controlled Release, 2018, 286, 279–288. doi: 10.1016/j.jconrel.2018.08.007
  4. Lyu, Z.; Kang, L.; Buuh, Z.Y.; Jiang, D.; McGuth, J.C.; Du, J.; Wissler, H.L.; Cai, W.; Wang, R.E. A Switchable Site-Specific Antibody Conjugate. ACS Chemical Biology, 2018, 13(4), 958–964. doi: 10.1021/acschembio.8b00107
Cy® is a trademark of GE Healthcare.